JPS5639085A - Chromone derivative and its preparation - Google Patents
Chromone derivative and its preparationInfo
- Publication number
- JPS5639085A JPS5639085A JP11476879A JP11476879A JPS5639085A JP S5639085 A JPS5639085 A JP S5639085A JP 11476879 A JP11476879 A JP 11476879A JP 11476879 A JP11476879 A JP 11476879A JP S5639085 A JPS5639085 A JP S5639085A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- chromone derivative
- preparation
- remedy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A chromone derivative of formula I (R1 is alkyl or optionally esterified COOH; X1, X2, X3, X4, X5 and X5 are H, halogen, NO2, OH or alkoxyl), and a salt thereof.
EXAMPLE: 2-(p-Hydroxyphenoxy)-5,7-dihydroxychromone.
USE: A hypotensive agent, a remedy for thrombosis, anti-inflammatory agent, or a remedy for cataract, and a synthetic intermediate therefor.
PROCESS: A compound of formula II [R2 is H; R3 is a group of formula III (R4 is alkyl, aryl, etc.), or R2 and R3 may form=P(R5)3 (R5 is alkyl, aryl, etc.)] is subjected to ring closure, preferably in a solvent, e.g. THF, in the presence of a base at 60W140°C, to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11476879A JPS5639085A (en) | 1979-09-06 | 1979-09-06 | Chromone derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11476879A JPS5639085A (en) | 1979-09-06 | 1979-09-06 | Chromone derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5639085A true JPS5639085A (en) | 1981-04-14 |
JPS6331470B2 JPS6331470B2 (en) | 1988-06-23 |
Family
ID=14646197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11476879A Granted JPS5639085A (en) | 1979-09-06 | 1979-09-06 | Chromone derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5639085A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992009594A1 (en) * | 1990-11-30 | 1992-06-11 | Tsumura & Co. | Chromone derivative and aldose reductase inhibitor containing the same as active ingredient |
JPH04249907A (en) * | 1990-12-27 | 1992-09-04 | Murata Mfg Co Ltd | Surface acoustic wave filter |
JPH04249906A (en) * | 1990-12-27 | 1992-09-04 | Murata Mfg Co Ltd | Surface acoustic wave filter |
JPH05327401A (en) * | 1992-05-21 | 1993-12-10 | Murata Mfg Co Ltd | Ceramic filter |
-
1979
- 1979-09-06 JP JP11476879A patent/JPS5639085A/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992009594A1 (en) * | 1990-11-30 | 1992-06-11 | Tsumura & Co. | Chromone derivative and aldose reductase inhibitor containing the same as active ingredient |
JPH04249907A (en) * | 1990-12-27 | 1992-09-04 | Murata Mfg Co Ltd | Surface acoustic wave filter |
JPH04249906A (en) * | 1990-12-27 | 1992-09-04 | Murata Mfg Co Ltd | Surface acoustic wave filter |
JPH05327401A (en) * | 1992-05-21 | 1993-12-10 | Murata Mfg Co Ltd | Ceramic filter |
Also Published As
Publication number | Publication date |
---|---|
JPS6331470B2 (en) | 1988-06-23 |
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