JPS5639085A - Chromone derivative and its preparation - Google Patents

Chromone derivative and its preparation

Info

Publication number
JPS5639085A
JPS5639085A JP11476879A JP11476879A JPS5639085A JP S5639085 A JPS5639085 A JP S5639085A JP 11476879 A JP11476879 A JP 11476879A JP 11476879 A JP11476879 A JP 11476879A JP S5639085 A JPS5639085 A JP S5639085A
Authority
JP
Japan
Prior art keywords
formula
alkyl
chromone derivative
preparation
remedy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11476879A
Other languages
Japanese (ja)
Other versions
JPS6331470B2 (en
Inventor
Yoshiyasu Koma
Haruo Horiai
Hiroyuki Kikuchi
Shuichi Takeno
Shinji Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP11476879A priority Critical patent/JPS5639085A/en
Publication of JPS5639085A publication Critical patent/JPS5639085A/en
Publication of JPS6331470B2 publication Critical patent/JPS6331470B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A chromone derivative of formula I (R1 is alkyl or optionally esterified COOH; X1, X2, X3, X4, X5 and X5 are H, halogen, NO2, OH or alkoxyl), and a salt thereof.
EXAMPLE: 2-(p-Hydroxyphenoxy)-5,7-dihydroxychromone.
USE: A hypotensive agent, a remedy for thrombosis, anti-inflammatory agent, or a remedy for cataract, and a synthetic intermediate therefor.
PROCESS: A compound of formula II [R2 is H; R3 is a group of formula III (R4 is alkyl, aryl, etc.), or R2 and R3 may form=P(R5)3 (R5 is alkyl, aryl, etc.)] is subjected to ring closure, preferably in a solvent, e.g. THF, in the presence of a base at 60W140°C, to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP11476879A 1979-09-06 1979-09-06 Chromone derivative and its preparation Granted JPS5639085A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11476879A JPS5639085A (en) 1979-09-06 1979-09-06 Chromone derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11476879A JPS5639085A (en) 1979-09-06 1979-09-06 Chromone derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5639085A true JPS5639085A (en) 1981-04-14
JPS6331470B2 JPS6331470B2 (en) 1988-06-23

Family

ID=14646197

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11476879A Granted JPS5639085A (en) 1979-09-06 1979-09-06 Chromone derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5639085A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992009594A1 (en) * 1990-11-30 1992-06-11 Tsumura & Co. Chromone derivative and aldose reductase inhibitor containing the same as active ingredient
JPH04249907A (en) * 1990-12-27 1992-09-04 Murata Mfg Co Ltd Surface acoustic wave filter
JPH04249906A (en) * 1990-12-27 1992-09-04 Murata Mfg Co Ltd Surface acoustic wave filter
JPH05327401A (en) * 1992-05-21 1993-12-10 Murata Mfg Co Ltd Ceramic filter

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992009594A1 (en) * 1990-11-30 1992-06-11 Tsumura & Co. Chromone derivative and aldose reductase inhibitor containing the same as active ingredient
JPH04249907A (en) * 1990-12-27 1992-09-04 Murata Mfg Co Ltd Surface acoustic wave filter
JPH04249906A (en) * 1990-12-27 1992-09-04 Murata Mfg Co Ltd Surface acoustic wave filter
JPH05327401A (en) * 1992-05-21 1993-12-10 Murata Mfg Co Ltd Ceramic filter

Also Published As

Publication number Publication date
JPS6331470B2 (en) 1988-06-23

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