JPS5788159A - 1,1,2,5-substituted isobiuret compound - Google Patents

1,1,2,5-substituted isobiuret compound

Info

Publication number
JPS5788159A
JPS5788159A JP16312280A JP16312280A JPS5788159A JP S5788159 A JPS5788159 A JP S5788159A JP 16312280 A JP16312280 A JP 16312280A JP 16312280 A JP16312280 A JP 16312280A JP S5788159 A JPS5788159 A JP S5788159A
Authority
JP
Japan
Prior art keywords
phenyl
expressed
isobiuret
compound
formulai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16312280A
Other languages
Japanese (ja)
Other versions
JPS6154784B2 (en
Inventor
Hajime Fujimura
Yasuzo Hiramatsu
Takahiro Yabuuchi
Masakatsu Kuki
Katsuo Takigawa
Takatsugu Honna
Hidekazu Miyake
Akira Kajitani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TAIHOU YAKUHIN KOGYO KK
Taiho Pharmaceutical Co Ltd
Original Assignee
TAIHOU YAKUHIN KOGYO KK
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TAIHOU YAKUHIN KOGYO KK, Taiho Pharmaceutical Co Ltd filed Critical TAIHOU YAKUHIN KOGYO KK
Priority to JP16312280A priority Critical patent/JPS5788159A/en
Publication of JPS5788159A publication Critical patent/JPS5788159A/en
Publication of JPS6154784B2 publication Critical patent/JPS6154784B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound expressed by formulaI(R1, R2 and R3 are lower alkyl; R4 is phenyl or phenyl having a halogen, lower alkyl, lower alkoxyl or trifluoromethyl as a substituent group).
EXAMPLE: 1,1,2-Trimethyl-5-phenyl-2-isobiuret.
USE: An medicine having anti-inflammatory, analgesic, antiallergic, diuretic, antimicrobial and anticonvulsant actions.
PROCESS: An isourea expressed by formula II is reacted with an isocyanate expressed by formula III in a solvent, e.g. ether, banzene or chloroform, or under solventless conditions at a temperature in the range of -20°C to the boiling point of the solvent to be used to afford the compound expressed by formulaI. The molar ratio of the isourea to the isocyanate is preferably about 1:1.
COPYRIGHT: (C)1982,JPO&Japio
JP16312280A 1980-11-18 1980-11-18 1,1,2,5-substituted isobiuret compound Granted JPS5788159A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16312280A JPS5788159A (en) 1980-11-18 1980-11-18 1,1,2,5-substituted isobiuret compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16312280A JPS5788159A (en) 1980-11-18 1980-11-18 1,1,2,5-substituted isobiuret compound

Publications (2)

Publication Number Publication Date
JPS5788159A true JPS5788159A (en) 1982-06-01
JPS6154784B2 JPS6154784B2 (en) 1986-11-25

Family

ID=15767591

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16312280A Granted JPS5788159A (en) 1980-11-18 1980-11-18 1,1,2,5-substituted isobiuret compound

Country Status (1)

Country Link
JP (1) JPS5788159A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4844428A (en) * 1971-09-16 1973-06-26

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4844428A (en) * 1971-09-16 1973-06-26

Also Published As

Publication number Publication date
JPS6154784B2 (en) 1986-11-25

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