MX2023008041A - Composiciones de acido nucleico-polipeptido y sus aplicaciones. - Google Patents

Composiciones de acido nucleico-polipeptido y sus aplicaciones.

Info

Publication number
MX2023008041A
MX2023008041A MX2023008041A MX2023008041A MX2023008041A MX 2023008041 A MX2023008041 A MX 2023008041A MX 2023008041 A MX2023008041 A MX 2023008041A MX 2023008041 A MX2023008041 A MX 2023008041A MX 2023008041 A MX2023008041 A MX 2023008041A
Authority
MX
Mexico
Prior art keywords
nucleic acid
polypeptide compositions
polymer
acid molecule
binding moiety
Prior art date
Application number
MX2023008041A
Other languages
English (en)
Spanish (es)
Inventor
Andrew John Geall
Venkata Ramana Doppalapudi
Michael Caramian COCHRAN
Rachel Elizabeth Johns
Palani Balu
Rob Burke
Beatrice Diana Darimont
David Sai-Ho Chu
Original Assignee
Avidity Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avidity Biosciences Inc filed Critical Avidity Biosciences Inc
Publication of MX2023008041A publication Critical patent/MX2023008041A/es

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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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