LV5749B4 - Farmaceitiska kompozicija kas satur ciklosporinus - Google Patents

Farmaceitiska kompozicija kas satur ciklosporinus

Info

Publication number
LV5749B4
LV5749B4 LV960265A LV960265A LV5749B4 LV 5749 B4 LV5749 B4 LV 5749B4 LV 960265 A LV960265 A LV 960265A LV 960265 A LV960265 A LV 960265A LV 5749 B4 LV5749 B4 LV 5749B4
Authority
LV
Latvia
Prior art keywords
pharmaceutical composition
composition containing
containing cyclosporins
cyclosporins
pharmaceutical
Prior art date
Application number
LV960265A
Other languages
English (en)
Latvian (lv)
Other versions
LV5749A4 (lv
Inventor
Birgit Hauer
Armin Meinzer
Ulrich Posanski
Friedrich Richter
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27264085&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV5749(B4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB888821754A external-priority patent/GB8821754D0/en
Priority claimed from GB898902903A external-priority patent/GB8902903D0/en
Priority claimed from GB898902900A external-priority patent/GB8902900D0/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of LV5749A4 publication Critical patent/LV5749A4/xx
Publication of LV5749B4 publication Critical patent/LV5749B4/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
LV960265A 1988-09-16 1996-07-18 Farmaceitiska kompozicija kas satur ciklosporinus LV5749B4 (lv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888821754A GB8821754D0 (en) 1988-09-16 1988-09-16 Improvements in/relating to organic compounds
GB898902903A GB8902903D0 (en) 1989-02-09 1989-02-09 Improvements in or relating to organic compounds
GB898902900A GB8902900D0 (en) 1989-02-09 1989-02-09 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
LV5749A4 LV5749A4 (lv) 1996-12-20
LV5749B4 true LV5749B4 (lv) 1997-04-20

Family

ID=27264085

Family Applications (1)

Application Number Title Priority Date Filing Date
LV960265A LV5749B4 (lv) 1988-09-16 1996-07-18 Farmaceitiska kompozicija kas satur ciklosporinus

Country Status (32)

Country Link
US (7) US5741512A (fr)
JP (1) JPH0725690B2 (fr)
KR (3) KR0148748B1 (fr)
AT (1) AT403435B (fr)
AU (1) AU627220B2 (fr)
BE (1) BE1003105A5 (fr)
BG (1) BG60525B2 (fr)
CA (1) CA1332150C (fr)
CH (1) CH679118A5 (fr)
DE (1) DE3930928C2 (fr)
DK (1) DK171433B1 (fr)
ES (1) ES2020738A6 (fr)
FI (1) FI98046C (fr)
FR (1) FR2636534B1 (fr)
GB (1) GB2222770B (fr)
GR (1) GR1000456B (fr)
HK (1) HK86593A (fr)
HU (1) HU211685A9 (fr)
ID (1) ID17863A (fr)
IE (1) IE60764B1 (fr)
IL (1) IL91642A (fr)
IT (1) IT1232243B (fr)
LU (1) LU87586A1 (fr)
LV (1) LV5749B4 (fr)
MY (1) MY107381A (fr)
NL (1) NL194781C (fr)
NO (1) NO180362C (fr)
NZ (1) NZ230660A (fr)
PH (1) PH31059A (fr)
PT (1) PT91731B (fr)
SE (2) SE8903042L (fr)
SG (1) SG50793G (fr)

Families Citing this family (182)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
GR1000466B (el) * 1989-01-28 1992-07-30 Sandoz Ag Μεθοδος παρασκευης νεων φαρμακευτικων μορφων κυκλοσπορινης.
BE1003009A5 (fr) * 1989-02-09 1991-10-22 Sandoz Sa Nouvelles compositions pharmaceutiques a base de cyclosporines.
US7081445B2 (en) * 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
HU208491B (en) * 1990-11-27 1993-11-29 Gyogyszerkutato Intezet Process for producing oral pharmaceutical composition containing cyclosporin
DE69229779T2 (de) * 1991-04-19 1999-12-23 Lds Technologies, Inc. Konvertierbare mikroemulsionsverbindungen
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
AU688920B2 (en) * 1991-06-27 1998-03-19 Novartis Ag Transesterified corn oil products
IL102236A0 (en) * 1991-06-27 1993-01-14 Ltt Inst Co Ltd Topical preparations containing cyclosporin
GB9208712D0 (en) * 1992-04-22 1992-06-10 Sandoz Ltd Pharmaceutical compositions containing cyclosporin derivates
WO1993023010A1 (fr) * 1992-05-13 1993-11-25 Sandoz Ltd. Compositions ophtalmiques contenant une cyclosporine
ES2168271T3 (es) * 1992-09-25 2002-06-16 Novartis Ag Composiciones farmaceuticas que contienen ciclosporinas.
PT697881E (pt) † 1993-04-20 2002-10-31 Novartis Ag Novas composicoes farmaceuticas contendo ciclosporina para administracao oral
NZ247516A (en) * 1993-04-28 1995-02-24 Bernard Charles Sherman Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
CH686761A5 (de) * 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
DE4447972B4 (de) * 1993-05-27 2007-12-27 Novartis Ag Galenische Formulierungen
AT408520B (de) * 1993-05-27 2001-12-27 Novartis Erfind Verwalt Gmbh Galenische formulierungen
DE4322826A1 (de) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmazeutisches Präparat
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
DK1033128T4 (da) * 1993-09-28 2012-03-19 Scherer Gmbh R P Blød gelatinekapselfremstilling
GB2315216B (en) * 1993-10-05 1998-10-14 Ciba Geigy Ag Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
DE4340781C3 (de) * 1993-11-30 2000-01-27 Novartis Ag Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung
KR0146671B1 (ko) * 1994-02-25 1998-08-17 김충환 사이클로스포린-함유 분말 조성물
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
US5474979A (en) * 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
FI100692B (fi) * 1994-05-24 1998-02-13 Leiras Oy Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä
GB2308545B (en) * 1994-10-26 1999-06-02 Novartis Ag Pharmaceutical microemulsion preconcentrates
IL115742A (en) * 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
EP0789580B1 (fr) 1994-11-03 2002-06-05 Novartis AG Nouvelles formes de preparations de cycylosporines pour administration par voie orale, de composition simple et haute biodisponibilite, et leur procede de production
US5603951A (en) * 1994-11-09 1997-02-18 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
KR0167613B1 (ko) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 사이클로스포린-함유 연질캅셀제 조성물
WO1996036316A1 (fr) * 1995-05-19 1996-11-21 Abbott Laboratories Formulations auto-emulsifiantes de medicaments lipophiles
US6696413B2 (en) * 1995-06-16 2004-02-24 Hexal Ag Pharmaceutical preparation with cyclosporin A
EP0760237A1 (fr) * 1995-08-30 1997-03-05 Cipla Limited Microémulsions huile-dans-l'eau
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
NZ280689A (en) * 1995-12-15 1997-08-22 Bernard Charles Sherma Sherman Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
CZ288631B6 (cs) * 1996-01-18 2001-08-15 Galena, A. S. Léčivé přípravky s obsahem cyklosporinu
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US6245349B1 (en) * 1996-02-23 2001-06-12 éLAN CORPORATION PLC Drug delivery compositions suitable for intravenous injection
KR970064620A (ko) * 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물
SE511313C2 (sv) 1997-01-13 1999-09-06 Gs Dev Ab Komposition med reglerad frisättning innefattande fettsyraester av diacylglycerol
ES2229473T3 (es) 1997-01-30 2005-04-16 Novartis Ag Composiciones farmaceuticas sin aceite que contienen ciclosporina a.
US6426078B1 (en) 1997-03-17 2002-07-30 Roche Vitamins Inc. Oil in water microemulsion
ATE215370T1 (de) * 1997-07-29 2002-04-15 Upjohn Co Selbstemulgierende formulierung enthaltend lipophile verbindungen
DE69808463T2 (de) 1997-07-29 2003-06-26 Pharmacia & Upjohn Co., Kalamazoo Selbstemulgierende formulierung enthaltend saure lipophile verbindungen
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
ATE314388T1 (de) 1997-10-08 2006-01-15 Isotechnika Inc Deuterierte und undeuterierte cyclosporin-analoga und ihre verwendung als immunmodulierende agentien
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
WO1999029335A1 (fr) * 1997-12-05 1999-06-17 Chong Kun Dang Corp. Composition pharmaceutique contenant de la ciclosporine
GB2380673B (en) * 1998-03-06 2003-05-28 Novartis Ag Emulsion preconcentrates containing cyclosporin or a macrolide
ID25908A (id) * 1998-03-06 2000-11-09 Novartis Ag Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
EP1091975B1 (fr) 1998-07-01 2005-12-14 Debiopharm S.A. Nouvelle cyclosporine ayant un profil d'activite ameliore
EP0977180B1 (fr) * 1998-07-30 2005-02-09 STMicroelectronics S.r.l. Méthode pour l'assemblage d'un actuateur pour disque dur, comprenant un transducteur pour lire et enregistrer, un microactuateur et une suspension et l'actuateur ainsi obtenu
PT982035E (pt) * 1998-08-18 2004-08-31 Panacea Biotec Ltd Composicao de ciclosporina compreendendo um veiculo hidrofilo
SE9804192D0 (sv) * 1998-12-03 1998-12-03 Scotia Lipidteknik Ab New formulation
GB2344520A (en) * 1998-12-08 2000-06-14 Phares Pharm Res Nv Pharmaceutical carriers comprising lipids and polymers
PL348193A1 (en) 1998-12-11 2002-05-06 Pharmasolutions Self-emulsifying compositions for drugs poorly soluble in water
NZ512599A (en) * 1998-12-30 2003-10-31 Dexcel Ltd Formulation for cyclosporin administration featuring a hydrophilic solvent and a surfactant with a HLB of less than 5
GB9903547D0 (en) 1999-02-16 1999-04-07 Novartis Ag Organic compounds
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6057289A (en) * 1999-04-30 2000-05-02 Pharmasolutions, Inc. Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system
GB9912476D0 (en) 1999-05-28 1999-07-28 Novartis Ag Organic compounds
DE19925001A1 (de) * 1999-05-31 2000-12-07 Pharma Concepts Gmbh & Co Kg Flüssiges Konzentrat
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
GB2355656B (en) * 1999-08-17 2004-04-07 Galena As Pharmaceutical compositions for oral and topical administration
JP2001122779A (ja) * 1999-10-26 2001-05-08 Toyo Capsule Kk 経口投与用シクロスポリン含有ミクロエマルジョン濃縮液
WO2001032142A1 (fr) * 1999-11-02 2001-05-10 Cipla Limited Formulation de cyclosporine
GB2362573A (en) * 2000-05-25 2001-11-28 Cipla Ltd Cyclosporin formulation
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US7919113B2 (en) * 1999-12-30 2011-04-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dispersible concentrate lipospheres for delivery of active agents
JP2003522578A (ja) 2000-02-18 2003-07-29 アーゴス インク 不均質組織における空間的に平均された励起−発光マップの生成
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
DE10029404B4 (de) * 2000-06-15 2009-10-29 Jagotec Ag Arzneiformulierung enthaltend Ciclosporin und deren Verwendung
US6623765B1 (en) * 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
AU2001225459B2 (en) * 2000-09-18 2005-12-22 Rpg Life Sciences Limited Selfemulsifiable formulation having enhanced bioabsorption and immunosuppression activities
US6960563B2 (en) * 2001-08-31 2005-11-01 Morton Grove Pharmaceuticals, Inc. Spontaneous emulsions containing cyclosporine
JP2005506990A (ja) * 2001-10-19 2005-03-10 アイソテクニカ インコーポレーテッド 新規のシクロスポリン類似体のマイクロエマルションプレコンセントレート
ES2326040T3 (es) * 2001-10-19 2009-09-29 Isotechnika Inc. Sintesis de analogos de ciclosporina.
AU2002231703B2 (en) 2001-12-14 2007-03-29 Jagotec Ag Pharmaceutical formulation comprising cyclosporin and use thereof
BR0215187A (pt) * 2001-12-20 2004-11-16 Bernard Charles Sherman Composições farmacêuticas que compreendem uma ciclosporina, um tensoativo hidrofìlico e um tensoativo lipofìlico
DE60222803T2 (de) * 2001-12-21 2008-07-17 Supernus Pharmaceuticals, Inc. Orale kapselformulierung mit verbesserter physikalischer stabilität
KR100441167B1 (ko) * 2001-12-27 2004-07-21 씨제이 주식회사 마이크로에멀젼 예비 농축액 조성물
US20040005339A1 (en) * 2002-06-28 2004-01-08 Shojaei Amir H. Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability
KR20040047056A (ko) * 2002-11-29 2004-06-05 한미약품 주식회사 비페닐디메틸디카복실레이트의 경구용 마이크로에멀젼조성물
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
KR100525234B1 (ko) * 2003-02-19 2005-10-28 한국유나이티드제약 주식회사 사이클로스포린 함유 연질캅셀제 및 그 제조방법
US20050196370A1 (en) * 2003-03-18 2005-09-08 Zhi-Jian Yu Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
US7181219B2 (en) 2003-05-22 2007-02-20 Lucent Technologies Inc. Wireless handover using anchor termination
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
US20060003002A1 (en) * 2003-11-03 2006-01-05 Lipocine, Inc. Pharmaceutical compositions with synchronized solubilizer release
CA2546347A1 (fr) 2003-11-21 2005-06-09 Combinatorx, Incorporated Procedes et reactifs destines au traitement de troubles inflammatoires
PE20050596A1 (es) * 2003-12-19 2005-10-18 Novartis Ag Microemulsion que comprende un inhibidor renina
IL159729A0 (en) * 2004-01-06 2004-06-20 Doron I Friedman Non-aqueous composition for oral delivery of insoluble bioactive agents
BRPI0506764A (pt) * 2004-01-09 2007-05-22 Wyeth Corp microemulsões para composições farmacêuticas
US20080249147A1 (en) * 2004-03-24 2008-10-09 Takeda Pharmaceutical Company Limited Emulsion-Stabilized Preparation
JPWO2005089716A1 (ja) * 2004-03-24 2008-01-31 武田薬品工業株式会社 高含量化製剤
CN101065139A (zh) * 2004-10-09 2007-10-31 扶瑞药业股份有限公司 眼用药剂递送系统
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) * 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
EP1848541A4 (fr) * 2005-02-07 2013-01-16 Pharmalight Inc Procede et dispositif d'administration ophtalmique d'ingredients pharmaceutiquement actifs
GB0504950D0 (en) * 2005-03-10 2005-04-20 Novartis Ag Organic compositions
AU2006259348B2 (en) 2005-06-17 2010-07-22 Novartis Ag Use of sanglifehrin in HCV
US7276476B2 (en) * 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
US7297679B2 (en) * 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US7288520B2 (en) 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7202209B2 (en) * 2005-07-13 2007-04-10 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) * 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
GT200600411A (es) * 2005-09-13 2007-05-21 Novartis Ag Combinaciones que comprenden un inhibidor del receptor del factor de crecimiento endotelial vascular
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
EP2218442A1 (fr) 2005-11-09 2010-08-18 CombinatoRx, Inc. Procédés, compositions et kits pour le traitement des maladies ophthalmiques
US11311477B2 (en) 2006-03-07 2022-04-26 Sgn Nanopharma Inc. Ophthalmic preparations
US10137083B2 (en) 2006-03-07 2018-11-27 SGN Nanopharma Inc Ophthalmic preparations
CA2645080A1 (fr) * 2006-03-07 2007-09-13 Novavax,Inc. Compositions nano-structurees et leurs procedes de fabrication et d'utilisation
US20070221693A1 (en) * 2006-03-24 2007-09-27 Moore Howard L Multi-purpose insulating and protective cover for containers
ITMI20060618A1 (it) * 2006-03-31 2007-10-01 Enitecnologie Spa Procedimento per la preparazione di nanoemulsioni acqua ion olio e olio in acqua
RU2448976C2 (ru) 2006-04-11 2012-04-27 Новартис Аг Ингибиторы hcv/вич и их применение
CN101573109A (zh) * 2006-12-28 2009-11-04 利默里克生物制药公司 用于治疗的方法和组合物
CA2674296C (fr) 2007-01-04 2015-11-24 Debiopharm Sa Cyclosporine non immunosuppressive pour le traitement de la dystrophie musculaire congenitale d'ullrich
WO2008122967A2 (fr) 2007-04-04 2008-10-16 Sigmoid Pharma Limited Composition pharmaceutique orale
WO2008132707A1 (fr) 2007-04-26 2008-11-06 Sigmoid Pharma Limited Fabrication de minicapsules multiples
EP2164466A1 (fr) * 2007-06-01 2010-03-24 Novo Nordisk A/S Préconcentrés spontanément dispersibles comprenant un médicament peptidique dans un excipient solide ou semi-solide
BRPI0814876A2 (pt) * 2007-07-31 2014-09-30 Limerick Biopharma Inc Análogos de pirona fosforilados e métodos
GB2451811A (en) 2007-08-09 2009-02-18 Ems Sa Delivery composition for solubilising water-insoluble pharmaceutical active ingredients
JP5668476B2 (ja) * 2007-10-08 2015-02-12 オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物
BRPI0705564B8 (pt) * 2007-10-10 2021-05-25 Embrapa Pesquisa Agropecuaria sistema do tipo cristal líquido contínuo contendo co-solvente portador de substâncias fracamente solúveis em água, seu processo de obtenção e seus usos
TW200932240A (en) * 2007-10-25 2009-08-01 Astellas Pharma Inc Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production
BRPI0907805A2 (pt) * 2008-02-28 2015-07-14 Novartis Ag Combinações para tratar dor associada à hiv
US8861813B2 (en) * 2008-03-13 2014-10-14 Mallinckrodt Llc Multi-function, foot-activated controller for imaging system
DE102008015299A1 (de) 2008-03-18 2009-09-24 Pkh Gmbh Halle Kolloidales Trägersystem
JP5749155B2 (ja) 2008-03-18 2015-07-15 ノボ・ノルデイスク・エー／エス プロテアーゼ安定化アシル化インスリンアナログ
WO2010080915A1 (fr) 2009-01-08 2010-07-15 Allergan, Inc. Compositions pour renforcer la croissance des ongles
US11304960B2 (en) * 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
US9278070B2 (en) 2009-05-18 2016-03-08 Sigmoid Pharma Limited Composition comprising oil drops
CN102458370A (zh) * 2009-06-09 2012-05-16 卢克斯生物科技公司 用于眼科用途的表面药物递送系统
EP2464341B1 (fr) 2009-08-12 2022-07-06 Sublimity Therapeutics Limited Compositions immunomodulatrices comprenant une matrice polymère et une phase huileuse
EP2308468A1 (fr) * 2009-10-08 2011-04-13 Novaliq GmbH Nouvelle composition pharmaceutique comportant un médicament contre l'immunosuppression macrolide
AR082453A1 (es) 2010-04-21 2012-12-12 Novartis Ag Compuestos de furopiridina, composiciones farmaceuticas que los contienen y usos de los mismos
US20120077778A1 (en) * 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EA201390532A1 (ru) 2010-10-08 2013-09-30 Новартис Аг Композиции сульфамидых ингибиторов ns3, содержащие витамин е
GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JO3337B1 (ar) * 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
FR2971941B1 (fr) 2011-02-24 2013-08-02 Physica Pharma Compositions pharmaceutiques administrables par voie cutanee et destinees au traitement local de la dermatite atopique canine
KR101510764B1 (ko) * 2011-10-10 2015-04-10 김용남 사이클로스포린 함유 안약 조성물 및 그 제조방법
MX2014012096A (es) 2012-04-11 2014-11-21 Novo Nordisk As Formulaciones de insulina.
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
US20140243300A1 (en) * 2013-02-28 2014-08-28 Precision Dermatology, Inc. Controlling the Bioavailability of Active Ingredients in Topical Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
WO2016033556A1 (fr) 2014-08-28 2016-03-03 Lipocine Inc. Esters de (17-β)-hydroxy-4-androstène-3-one biodisponibles à l'état solide
WO2016033549A2 (fr) 2014-08-28 2016-03-03 Lipocine Inc. Compositions de (17-ss)-3-oxoandrost-4-èn-17-yl tridécanoate et leurs procédés de préparation et d'utilisation
EA036036B1 (ru) 2014-11-07 2020-09-16 Сигмойд Фарма Лимитед Композиции, содержащие циклоспорин
EP3187172A1 (fr) * 2016-01-04 2017-07-05 Spherium Biomed S.L. Compositions topiques de cyclosporine a
JP2020503269A (ja) 2016-11-28 2020-01-30 リポカイン インコーポレーテッド 経口ウンデカン酸テストステロン療法
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
WO2019002362A1 (fr) * 2017-06-28 2019-01-03 Spherium Biomed, S.L. Compositions topiques de cyclosporine a
KR102146704B1 (ko) 2018-04-13 2020-08-21 가천대학교 산학협력단 사이클로스포린 A (CsA) 경피 및 피내 약물전달용 마이크로구조체
MX2021006010A (es) * 2018-11-26 2021-09-21 Hepion Pharmaceuticals Inc Formulaciones farmaceuticas para analogos de ciclosporina.

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH246178A (de) * 1942-01-28 1946-12-15 Reichstein Tadeus Dr Prof Verfahren zur Herstellung einer neuen Verbindung der Cyclopentano-polyhydrophenanthrenreihe.
FR1274354A (fr) * 1956-03-10 1961-10-27 Agents tensio-actifs obtenus à partir de triglycérides et polyéthylène glycol
GB1171125A (en) * 1966-06-08 1969-11-19 Glaxo Lab Ltd Improvements in or relating to Injectable Preparations
JPS5114746B1 (fr) * 1970-12-31 1976-05-12
US3813345A (en) * 1971-08-05 1974-05-28 Vanguard Chem Co Inc Method of producing microcolloidal aqueous emulsions of unsaturated organic compounds
US3954967A (en) * 1971-08-05 1976-05-04 Vanguard Chemical Company, Inc. Method of producing microcolloidal aqueous emulsions of unsaturated organic insecticidal compounds
US4073943A (en) * 1974-09-11 1978-02-14 Apoteksvarucentralen Vitrum Ab Method of enhancing the administration of pharmalogically active agents
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
CH636013A5 (en) * 1978-03-07 1983-05-13 Sandoz Ag More readily absorbable pharmaceutical composition
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
CH641356A5 (en) * 1979-02-27 1984-02-29 Sandoz Ag Pharmaceutical compositions containing cyclosporin
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
AU558155B2 (en) * 1982-02-01 1987-01-22 Sandoz Ltd. Treating multiple sclerosis with dihydro-cyclosporin d
DE3225706C2 (de) * 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
DE3235612A1 (de) * 1982-09-25 1984-03-29 Bayer Ag, 5090 Leverkusen Mikroemulsionen
DE3237814A1 (de) * 1982-10-12 1984-04-12 Warner-Lambert Co., 07950 Morris Plains, N.J. Wasserfreie emulsionen und verwendung derselben
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
JPS6024776A (ja) * 1983-07-19 1985-02-07 Fujitsu Ltd 中間調画像圧縮方式
JPS6061535A (ja) * 1983-08-24 1985-04-09 エフ・ホフマン・ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト 製薬学的組成物
FR2553661B1 (fr) * 1983-10-19 1985-12-20 Rhone Poulenc Sante Nouvelles microemulsions pharmaceutiquement acceptables
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
US4605422A (en) 1984-03-30 1986-08-12 Union Carbide Corporation Oil-in-alcohol microemulsion
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4794000A (en) * 1987-01-08 1988-12-27 Synthetic Blood Corporation Coacervate-based oral delivery system for medically useful compositions
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
DE3580717D1 (de) * 1984-08-02 1991-01-10 Sandoz Ag Pharmazeutische anwendung von (nva)2-cyclosporine.
CH662944A5 (it) * 1984-10-18 1987-11-13 Pier Luigi Prof Dr Luisi Procedimento per la preparazione di biocompatibili di micelle inverse di biocompatibili e loro utilizzazione.
JPS61280435A (ja) * 1985-04-04 1986-12-11 Kanji Takada サイクロスポリン類のリンパ指向性製剤
JPS61249918A (ja) * 1985-04-26 1986-11-07 Yutaka Mizushima 点眼剤
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
US4797272A (en) * 1985-11-15 1989-01-10 Eli Lilly And Company Water-in-oil microemulsions for cosmetic uses
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
SE457693B (sv) * 1986-07-01 1989-01-23 Drilletten Ab Komposition med reglerad frigoering vari ett biologiskt material aer loest eller dispergerat i en l2-fas
EP0256856A3 (fr) * 1986-08-14 1989-01-11 Synthetic Blood Corporation Composition pour l'administration parentérale
DE3629386A1 (de) * 1986-08-29 1988-03-03 Scherer Gmbh R P Gelatinekapseln und verfahren zu ihrer herstellung
HU205861B (en) * 1986-12-19 1992-07-28 Sandoz Ag Process for producing hydrosole of pharmaceutically effective material
DE3707711A1 (de) * 1987-03-11 1988-09-22 Hoechst Ag Oel-in-wasser-emulsionen, verfahren zu deren herstellung und deren verwendung
CA1301642C (fr) * 1987-03-30 1992-05-26 Howard Bernard Dawson Formulations chimiques
US4798823A (en) * 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
DE3884470T2 (de) * 1987-06-17 1994-03-10 Sandoz Ag Cyclosporine und deren Benutzung als Arzneimittel.
GB2206119B (en) * 1987-06-22 1990-10-31 Merck & Co Inc A new cyclosporin derivative with modified "8-amino acid"
US4835002A (en) * 1987-07-10 1989-05-30 Wolf Peter A Microemulsions of oil in water and alcohol
DK483587D0 (da) * 1987-09-15 1987-09-15 Riemann & Co Aps Claus Antiperspirant praeparat
HU205010B (en) * 1987-09-15 1992-03-30 Sandoz Ag Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
US4914188A (en) * 1987-11-16 1990-04-03 Merck & Co., Inc. Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin
HU203564B (en) * 1987-12-21 1991-08-28 Sandoz Ag Process for producing new orthorombos cyclosporin without solvatation
ES2033086T3 (es) * 1988-01-29 1993-03-01 Sankyo Company Limited Un procedimiento para la preparacion de una composicion farmaceutica.
JPH01249918A (ja) * 1988-03-30 1989-10-05 Kubota Ltd 強制送風式エンジンの放熱器の防塵装置
CH679119A5 (fr) * 1988-05-13 1991-12-31 Sandoz Ag
HU201567B (en) * 1988-07-21 1990-11-28 Gyogyszerkutato Intezet Process for production of intravenous medical compositions containing cyclosphorin
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
BE1003578A4 (fr) * 1988-10-26 1992-04-28 Sandoz Sa Nouvelles compositions ophtalmiques a base d'une cyclosporine.
BE1003009A5 (fr) * 1989-02-09 1991-10-22 Sandoz Sa Nouvelles compositions pharmaceutiques a base de cyclosporines.
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
GB9208712D0 (en) * 1992-04-22 1992-06-10 Sandoz Ltd Pharmaceutical compositions containing cyclosporin derivates

Also Published As

Publication number Publication date
FI894342A0 (fi) 1989-09-14
GB2222770A (en) 1990-03-21
GR1000456B (el) 1992-07-30
CH679118A5 (fr) 1991-12-31
GR890100583A (en) 1990-10-31
IT1232243B (it) 1992-01-28
HU211685A9 (en) 1995-12-28
AT403435B (de) 1998-02-25
US20030143250A1 (en) 2003-07-31
FR2636534A1 (fr) 1990-03-23
FI894342A (fi) 1990-03-17
ES2020738A6 (es) 1991-09-16
KR900004348A (ko) 1990-04-12
KR100446170B1 (ko) 2004-11-20
SE514303C2 (sv) 2001-02-05
US6024978A (en) 2000-02-15
US5866159A (en) 1999-02-02
ID17863A (id) 1998-01-29
MY107381A (en) 1995-11-30
PT91731A (pt) 1990-03-30
BE1003105A5 (fr) 1991-11-26
FI98046B (fi) 1996-12-31
NL194781B (nl) 2002-11-01
DK455989D0 (da) 1989-09-15
SE8903042L (sv) 1990-05-11
KR100894130B1 (ko) 2009-04-20
SG50793G (en) 1993-06-25
NL8902315A (nl) 1990-04-17
GB2222770B (en) 1992-07-29
NO893678D0 (no) 1989-09-14
NZ230660A (en) 1992-06-25
US5741512A (en) 1998-04-21
NO180362C (no) 1997-04-09
BG60525B2 (bg) 1995-07-28
JPH0725690B2 (ja) 1995-03-22
IE892939L (en) 1990-03-16
LU87586A1 (fr) 1991-05-07
IE60764B1 (en) 1994-08-10
IT8948369A0 (it) 1989-09-15
IL91642A (en) 1994-04-12
PT91731B (pt) 1995-08-09
US5916589A (en) 1999-06-29
DK455989A (da) 1990-03-17
LV5749A4 (lv) 1996-12-20
AU627220B2 (en) 1992-08-20
JPH02121929A (ja) 1990-05-09
DE3930928A1 (de) 1990-03-22
NL194781C (nl) 2003-03-04
KR0148748B1 (ko) 1998-08-17
GB8920597D0 (en) 1989-10-25
SE8903042D0 (sv) 1989-09-15
FR2636534B1 (fr) 1994-09-09
DK171433B1 (da) 1996-10-28
AU4140089A (en) 1990-03-22
PH31059A (en) 1998-02-05
IL91642A0 (en) 1990-04-29
ATA214289A (de) 1997-07-15
US5962017A (en) 1999-10-05
US5962014A (en) 1999-10-05
HK86593A (en) 1993-08-27
FI98046C (fi) 1997-04-10
NO180362B (no) 1996-12-30
CA1332150C (fr) 1994-09-27
DE3930928C2 (de) 1994-06-01
US7235248B2 (en) 2007-06-26
NO893678L (no) 1990-03-19
KR20070108289A (ko) 2007-11-09

Similar Documents

Publication Publication Date Title
LV5749A4 (lv) Farmaceitiska kompozicija kas satur ciklosporinus
DE10199066I1 (de) Pharmazeutische Zusammensetzung
DE122004000023I2 (de) Pharmazeutische Zusammensetzung
IT1232677B (it) Composizione farmaceutica contenente ranitidina
BR8905204A (pt) Composicao colutoria
DK481989D0 (da) Farmaceutiske formuleringer
DK229489D0 (da) Laegemiddeladsorbater
ATA165489A (de) Nitroglycerinhaltige spray-präparate
KR890701101A (ko) 제약학적 조성물
IT8820386A0 (it) Composizioni farmaceutiche orosolubili contenti acetilcisteina.
BR8906787A (pt) Composicao
FI893643A (fi) Farmaceutiska kompositioner.
DK548689D0 (da) Farmaceutisk oploesning
BR8902491A (pt) Composicao
TR26099A (tr) Islah edilmis pestisid terkip
BR8907528A (pt) Composicao crio-protetora
IT8819731A0 (it) Composizioni farmaceutiche contenenti timosina alfa 1.
ATA133288A (de) Pharmazeutische zusammensetzung
DE68902056D1 (de) 4-aroylimidazol-2-on enthaltende pharmazeutische zusammensetzung.
DE68907609D1 (de) Arzneimittelzusammensetzung.
DK205590A (da) Farmaceutisk nifedipinholdigt praeparat
BR8900587A (pt) Composicoes
IT1224244B (it) Composizione farmaceutica anoressizzante comprendente 5-idrossitrpofano
ATA246089A (de) Pharmazeutische zusammensetzung enthaltend phenylcarbamate
DE68928589D1 (de) Speicheranordnung