KR920700289A - 허피스바이러스 재조합 천연두바이러스 백신 - Google Patents
허피스바이러스 재조합 천연두바이러스 백신Info
- Publication number
- KR920700289A KR920700289A KR1019900702630A KR900702630A KR920700289A KR 920700289 A KR920700289 A KR 920700289A KR 1019900702630 A KR1019900702630 A KR 1019900702630A KR 900702630 A KR900702630 A KR 900702630A KR 920700289 A KR920700289 A KR 920700289A
- Authority
- KR
- South Korea
- Prior art keywords
- virus
- herpes
- equine
- smallpox
- glycoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 241001529453 unidentified herpesvirus Species 0.000 title claims 31
- 229940124860 Smallpox virus vaccine Drugs 0.000 title 1
- 241000700605 Viruses Species 0.000 claims description 31
- 101710099276 Probable metalloendopeptidase Proteins 0.000 claims description 11
- 241000700647 Variola virus Species 0.000 claims 47
- 241000230501 Equine herpesvirus sp. Species 0.000 claims 43
- 102000003886 Glycoproteins Human genes 0.000 claims 36
- 108090000288 Glycoproteins Proteins 0.000 claims 36
- 229960005486 vaccine Drugs 0.000 claims 22
- 241000701044 Human gammaherpesvirus 4 Species 0.000 claims 14
- 230000002496 gastric effect Effects 0.000 claims 14
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 claims 13
- 241000711798 Rabies lyssavirus Species 0.000 claims 12
- 101700012268 Holin Proteins 0.000 claims 9
- 101710124413 Portal protein Proteins 0.000 claims 9
- 101710112672 Probable tape measure protein Proteins 0.000 claims 9
- 101710194975 Uncharacterized protein gp14 Proteins 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 241000283690 Bos taurus Species 0.000 claims 5
- 241000283073 Equus caballus Species 0.000 claims 5
- 241000701087 Felid alphaherpesvirus 1 Species 0.000 claims 5
- 241000701024 Human betaherpesvirus 5 Species 0.000 claims 5
- 230000028993 immune response Effects 0.000 claims 4
- 244000052769 pathogen Species 0.000 claims 4
- 230000001717 pathogenic effect Effects 0.000 claims 4
- 238000005215 recombination Methods 0.000 claims 4
- 230000006798 recombination Effects 0.000 claims 4
- 101000686824 Enterobacteria phage N4 Virion DNA-directed RNA polymerase Proteins 0.000 claims 3
- 101001095863 Enterobacteria phage T4 RNA ligase 1 Proteins 0.000 claims 3
- 101000644628 Escherichia phage Mu Tail fiber assembly protein U Proteins 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 241000178270 Canarypox virus Species 0.000 claims 2
- 241000282465 Canis Species 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 206010037742 Rabies Diseases 0.000 claims 2
- 241000700618 Vaccinia virus Species 0.000 claims 2
- 230000036039 immunity Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 230000008774 maternal effect Effects 0.000 claims 2
- 201000006082 Chickenpox Diseases 0.000 claims 1
- 241000700662 Fowlpox virus Species 0.000 claims 1
- 206010046980 Varicella Diseases 0.000 claims 1
- 230000000890 antigenic effect Effects 0.000 claims 1
- 238000007788 roughening Methods 0.000 claims 1
- 241000701081 Equid alphaherpesvirus 1 Species 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
- C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33900489A | 1989-04-17 | 1989-04-17 | |
| US339,004 | 1989-04-17 | ||
| US39448889A | 1989-08-16 | 1989-08-16 | |
| US394,488 | 1989-08-16 | ||
| US07/502,834 US5338683A (en) | 1981-12-24 | 1990-04-04 | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| US502,834 | 1990-04-04 | ||
| PCT/US1990/002094 WO1990012882A1 (en) | 1989-04-17 | 1990-04-16 | Herpes virus recombinant poxvirus vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR920700289A true KR920700289A (ko) | 1992-02-19 |
Family
ID=27407304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900702630A Withdrawn KR920700289A (ko) | 1989-04-17 | 1990-04-16 | 허피스바이러스 재조합 천연두바이러스 백신 |
Country Status (17)
Families Citing this family (163)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5505941A (en) * | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US4603112A (en) * | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US7767449B1 (en) | 1981-12-24 | 2010-08-03 | Health Research Incorporated | Methods using modified vaccinia virus |
| US7045313B1 (en) | 1982-11-30 | 2006-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA |
| US5674735A (en) * | 1990-07-06 | 1997-10-07 | University Court Of The University Of Glasgow | DNA encoding the EHV-4 gH or gC glycoprotein |
| GB9014950D0 (en) * | 1990-07-06 | 1990-08-29 | Univ Glasgow | Ehv-4 glycoprotein vaccine |
| US7374768B1 (en) * | 1990-09-25 | 2008-05-20 | Xenova Research Limited | Viral vaccines |
| EP0550553B1 (en) * | 1990-09-25 | 2000-07-12 | Cantab Pharmaceuticals Research Limited | Viral defective vaccine produced by transcomplementing cell line |
| US5997878A (en) | 1991-03-07 | 1999-12-07 | Connaught Laboratories | Recombinant poxvirus-cytomegalovirus, compositions and uses |
| US5759552A (en) * | 1991-03-07 | 1998-06-02 | Virogenetics Corporation | Marek's disease virus recombinant poxvirus vaccine |
| GB9105383D0 (en) * | 1991-03-14 | 1991-05-01 | Immunology Ltd | An immunotherapeutic for cervical cancer |
| ATE181108T1 (de) * | 1991-08-26 | 1999-06-15 | Immuno Ag | Direkt molekuläre klonierung eines modifizierten genoms eines chordopocken-virus |
| ATE253123T1 (de) * | 1991-08-26 | 2003-11-15 | Baxter Healthcare Sa | Ein intaktes fpv-tk-gen enthaltender rekombinanter virus der vogelpocken |
| US5869312A (en) * | 1992-01-13 | 1999-02-09 | Syntro Corporation | Recombinant swinepox virus |
| US6136318A (en) * | 1993-02-26 | 2000-10-24 | Cochran; Mark D. | Recombinant fowlpox viruses and uses thereof |
| CA2156423A1 (en) * | 1993-02-26 | 1994-09-01 | Mark D. Cochran | Recombinant fowlpox viruses and uses thereof |
| US5925358A (en) * | 1993-02-26 | 1999-07-20 | Syntro Corporation | Recombinant fowlpox viruses and uses thereof |
| US6010703A (en) * | 1993-07-26 | 2000-01-04 | Board Of Trustees Operating Michigan State University | Recombinant poxvirus vaccine against feline rhinotracheitis |
| AU683557B2 (en) * | 1994-03-30 | 1997-11-13 | Virogenetics Corporation | Nucleotide and amino acid sequences of canine herpesvirus GB, GC and GD and uses therefor |
| ES2243937T3 (es) * | 1994-04-29 | 2005-12-01 | Baxter Healthcare S.A. | Poxvirus recombinados en regiones esenciales con la ayuda de polinucleotidos extraños. |
| WO1998000166A1 (en) | 1996-07-03 | 1998-01-08 | Merial, Inc. | Recombinant canine adenovirus (cav) containing exogenous dna |
| US6183752B1 (en) * | 1997-02-05 | 2001-02-06 | Pasteur Merieux Serums Et Vaccins | Restenosis/atherosclerosis diagnosis, prophylaxis and therapy |
| US6517843B1 (en) | 1999-08-31 | 2003-02-11 | Merial | Reduction of porcine circovirus-2 viral load with inactivated PCV-2 |
| US6224882B1 (en) | 1997-11-07 | 2001-05-01 | Protein Science Corp. | Insect cells or fractions as adjuvant for antigens |
| AP1261A (en) | 1998-02-24 | 2004-03-19 | Sisters Of Providence In Oregon | Composition containing an OX-40 receptor binding agent or a nucleic acid encoding the same and methods for enhancing antigen-specific immune response. |
| CA2322160C (en) | 1998-02-27 | 2013-01-29 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
| AU3498200A (en) | 1999-02-19 | 2000-09-04 | Michigan State University | An antigen test to detect equine protozoal myeloencephalitis in horse serum and cerebrospinal fluid |
| BR0008645A (pt) | 1999-03-03 | 2002-01-22 | Univ Pennsylvania | Métodos de induzir uma resposta imunológica contra um imunógeno em um indivìduo, de reduzir rejeição de células, tecido ou órgão doadores nã0-assemelhados em um indivìduo e uma resposta imunológica dominante em um indivìduo e de expandir uma subpopulação de células t associadas com uma resposta imunológica especìfica, plasmìdeo, e, composição |
| AU779395B2 (en) * | 1999-04-30 | 2005-01-20 | Institut De Recherche Cliniques De Montreal (Ircm) | Mutant human CD80 and compositions for and methods of making and using the same |
| PL210451B1 (pl) * | 1999-06-10 | 2012-01-31 | Merial Sas | Szczepionka DNA przeciwko wirusowi nosówki psów (CDV) |
| WO2000076538A1 (en) | 1999-06-10 | 2000-12-21 | Michigan State University | Feline calicivirus isolated from cat urine and vaccines thereof |
| US7419668B1 (en) | 1999-09-02 | 2008-09-02 | Board Of Trustees Of Michigan State University | Vaccine to control equine protozoal myeloencephalitis in horses |
| WO2001015708A1 (en) | 1999-09-02 | 2001-03-08 | Michigan State University | Vaccine to control equine protozoal myeloencephalitis in horses |
| CA2394648C (en) * | 1999-12-21 | 2010-07-20 | Merial | Compositions and vaccines containing antigen(s) of cryptosporidium parvum and of another enteric pathogen |
| ES2307640T3 (es) * | 2000-07-14 | 2008-12-01 | The Trustees Of The University Of Pennsylvania | Vacunad de adn codificantes de proteinas accesorias del vih. |
| US6733994B2 (en) * | 2000-10-04 | 2004-05-11 | The Trustees Of The University Of Pennsylvania | Highly expressible genes |
| US7628980B2 (en) * | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| MXPA03002513A (es) * | 2000-11-23 | 2004-09-10 | Bavarian Nordic As | Variante modificada de virus vaccinia ankara. |
| US7097842B2 (en) * | 2000-11-23 | 2006-08-29 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| US20020108132A1 (en) * | 2001-02-02 | 2002-08-08 | Avigenics Inc. | Production of a monoclonal antibody by a transgenic chicken |
| US7176300B2 (en) * | 2001-03-30 | 2007-02-13 | Avigenics, Inc. | Avian lysozyme promoter |
| AU2002255995A1 (en) * | 2001-03-30 | 2002-10-15 | Avigenics, Inc. | Avian lysozyme promoter |
| US7541512B2 (en) * | 2001-03-30 | 2009-06-02 | Synageva Biopharma Corp. | Avians containing a lysozyme promoter transgene |
| US20040037848A1 (en) * | 2001-04-06 | 2004-02-26 | Audonnet Jean-Christophe Francis | Recombinant vaccine against West Nile Virus |
| FR2823222B1 (fr) | 2001-04-06 | 2004-02-06 | Merial Sas | Vaccin contre le virus de la fievre du nil |
| US7740863B2 (en) * | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| AU2002329176A1 (en) | 2001-05-25 | 2002-12-23 | The Trustees Of The University Of Pennsylvania | Targeted particles and methods of using the same |
| US7550650B2 (en) * | 2001-09-18 | 2009-06-23 | Synageva Biopharma Corp. | Production of a transgenic avian by cytoplasmic injection |
| US6875588B2 (en) | 2001-11-30 | 2005-04-05 | Avigenics, Inc. | Ovomucoid promoter and methods of use |
| US20100333219A1 (en) * | 2001-11-30 | 2010-12-30 | Synageva Biopharma Corp. | Methods of protein production using ovomucoid regulatory regions |
| US7335761B2 (en) * | 2001-11-30 | 2008-02-26 | Avigenics, Inc. | Avian gene expression controlling regions |
| US7294507B2 (en) * | 2001-11-30 | 2007-11-13 | Avigenics, Inc. | Ovomucoid promoters and methods of use |
| US7135562B2 (en) * | 2002-03-14 | 2006-11-14 | University Of Cincinnati | Avian iFABP gene expression controlling region |
| US20040241723A1 (en) * | 2002-03-18 | 2004-12-02 | Marquess Foley Leigh Shaw | Systems and methods for improving protein and milk production of dairy herds |
| KR20110017904A (ko) * | 2002-04-19 | 2011-02-22 | 버베리안 노딕 에이/에스 | 신생아의 백신접종용 변형 백시니아 바이러스 안카라 |
| EA012160B1 (ru) * | 2002-05-16 | 2009-08-28 | Бавариан Нордик А/С | Рекомбинантный поксвирус, экспрессирующий гомологичные гены, встроенные в поксвирусный геном, и его применение |
| JP2005537793A (ja) * | 2002-09-05 | 2005-12-15 | バヴァリアン・ノルディック・アクティーゼルスカブ | 無血清条件下で初代細胞を培養する方法及びウイルスを増幅させる方法 |
| AU2003296974A1 (en) * | 2002-12-13 | 2004-07-14 | Aventis Pasteur, Inc. | Production of alvac on avian embryonic stem cells |
| CN1980571A (zh) * | 2003-01-24 | 2007-06-13 | 阿维季尼克斯股份有限公司 | 禽类及禽蛋中表达的外源蛋白质 |
| US7262027B2 (en) * | 2003-03-14 | 2007-08-28 | Medical College Of Ohio | Polypeptide and DNA immunization against Coccidioides spp. infections |
| EP2390352A1 (en) | 2003-03-18 | 2011-11-30 | Quantum Genetics Ireland Limited | Systems and methods for improving protein and milk production of dairy herds |
| US7468273B2 (en) | 2003-05-01 | 2008-12-23 | Meial Limited | Canine GHRH gene, polypeptides and methods of use |
| JP2007502868A (ja) | 2003-06-13 | 2007-02-15 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | ワクチン、免疫治療剤及び使用方法 |
| NZ570709A (en) * | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
| CA2545886A1 (en) | 2003-11-13 | 2005-06-02 | University Of Georgia Research Foundation, Inc. | Methods of characterizing infectious bursal disease virus |
| MXPA06009452A (es) | 2004-02-19 | 2007-03-15 | Univ Alberta | Polimorfismos del promotor de leptin y sus usos. |
| WO2007050095A2 (en) | 2004-11-19 | 2007-05-03 | The Trustees Of The University Of Pennsylvania | Improved vaccines and methods for using the same |
| JP5022906B2 (ja) * | 2004-11-24 | 2012-09-12 | テラプトシス エス アー | カスパーゼ−2/−6二重阻害剤として有用な新規ペプチドおよびそれらの生物学的適用 |
| RS51324B (sr) | 2005-04-25 | 2010-12-31 | Merial Ltd. | Vakcine protiv nipah virusa |
| EP2292250A1 (en) * | 2005-07-28 | 2011-03-09 | Pfizer Products Inc. | Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline parvovirus and feline herpes virus |
| US20080241184A1 (en) | 2005-08-25 | 2008-10-02 | Jules Maarten Minke | Canine influenza vaccines |
| US7771995B2 (en) | 2005-11-14 | 2010-08-10 | Merial Limited | Plasmid encoding human BMP-7 |
| EP1951751B1 (en) | 2005-11-14 | 2017-11-01 | Merial, Inc. | Gene therapy for renal failure |
| US7745158B2 (en) * | 2005-12-14 | 2010-06-29 | Kimberly-Clark Worldwide, Inc. | Detection of secreted aspartyl proteases from Candida species |
| KR101421745B1 (ko) | 2006-01-13 | 2014-07-22 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 코돈 최적화된 il―15를 사용하는 백신 및 면역치료제, 및 그의 사용 방법 |
| WO2007082105A2 (en) | 2006-01-16 | 2007-07-19 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chlamydia vaccine |
| WO2007115059A2 (en) | 2006-03-29 | 2007-10-11 | Merial Limited | Vaccine against streptococci |
| EP2023954B1 (en) * | 2006-05-19 | 2013-07-17 | Sanofi Pasteur, Inc. | Immunological composition |
| US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
| CN105132439A (zh) | 2006-07-28 | 2015-12-09 | 宾夕法尼亚大学托管会 | 改进的疫苗及其使用方法 |
| US8202967B2 (en) | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| WO2008091311A1 (en) | 2007-01-26 | 2008-07-31 | Synageva Biopharma Corp | Transgene expression in avians |
| CA2684923C (en) | 2007-05-02 | 2015-01-06 | Merial Limited | Dna plasmids having improved expression and stability |
| TW200907058A (en) * | 2007-05-30 | 2009-02-16 | Wyeth Corp | Raccoon poxvirus expressing rabies glycoproteins |
| US20090246226A1 (en) * | 2008-03-28 | 2009-10-01 | Zeon Corporation | Avian vaccines possessing a positive marker gene |
| EP2265715B1 (en) | 2008-04-04 | 2016-12-28 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same |
| EP2274442B1 (en) * | 2008-04-04 | 2016-06-29 | The Trustees Of The University Of Pennsylvania | Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same |
| CN102066411A (zh) | 2008-05-08 | 2011-05-18 | 梅里亚有限公司 | 使用白蛉唾液免疫原的利什曼原虫疫苗 |
| JP5753090B2 (ja) | 2008-10-29 | 2015-07-22 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 改良型hcvワクチンおよびその使用方法 |
| US8921536B2 (en) | 2008-10-29 | 2014-12-30 | The Trustees Of The University Of Pennsylvania | HCV vaccines and methods for using the same |
| CA2653478A1 (en) | 2009-01-23 | 2010-07-23 | Gregg Martin | Automated wash system for industrial vehicles |
| US9050287B2 (en) | 2009-01-23 | 2015-06-09 | The Trustees Of The University Of Pennsylvania | Vaccines for human papilloma virus and methods for using the same |
| US20100192236A1 (en) * | 2009-01-28 | 2010-07-29 | University Of South Carolina | Modulation of Delta Opioid Receptor Expression |
| CA2757030C (en) | 2009-04-03 | 2019-01-15 | Merial Limited | Vectors comprising newcastle disease viruses and compositions thereof |
| US20100284977A1 (en) * | 2009-04-28 | 2010-11-11 | University Of South Carolina | Expression of Anti-Nociceptive Compounds from Endogenously Regulated Promoters |
| US9670506B2 (en) | 2009-04-30 | 2017-06-06 | Consejo Superior De Investigaciones Cientificas | Modified immunization vectors |
| AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
| CA2771334A1 (en) | 2009-09-14 | 2011-03-17 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics comprising il-15 receptor alpha and/or nucleic acid molecules encoding the same, and methods for using the same |
| CA3030893C (en) | 2009-11-02 | 2022-11-29 | The Trustees Of The University Of Pennsylvania | Foot and mouth disease virus (fmdv) consensus proteins, coding sequences therefor and vaccines made therefrom |
| US8298820B2 (en) | 2010-01-26 | 2012-10-30 | The Trustees Of The University Of Pennsylvania | Influenza nucleic acid molecules and vaccines made therefrom |
| AU2011213559B2 (en) | 2010-02-08 | 2015-05-07 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding RANTES, and compositions comprising and methods of using the same |
| WO2012023033A2 (en) | 2010-08-18 | 2012-02-23 | Purdue Pharma L.P. | Improved peptide immunogens |
| CA2809127C (en) | 2010-08-31 | 2019-04-02 | Merial Limited | Newcastle disease virus vectored herpesvirus vaccines |
| AR083533A1 (es) | 2010-10-22 | 2013-03-06 | Boehringer Ingelheim Vetmed | Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe |
| KR102557275B1 (ko) | 2010-11-12 | 2023-07-19 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 공통 전립선 항원, 이것을 암호화하는 핵산 분자, 그리고 이것을 포함하는 백신 및 용도 |
| WO2012090073A2 (en) | 2010-12-30 | 2012-07-05 | The Netherlands Cancer Institute | Methods and compositions for predicting chemotherapy sensitivity |
| CN107090463A (zh) | 2011-01-31 | 2017-08-25 | 宾夕法尼亚大学托管会 | 编码新型疱疹抗原的核酸分子、包含所述核酸分子的疫苗及其使用方法 |
| US9238679B2 (en) | 2011-02-11 | 2016-01-19 | The Trustees Of The University Of Pennslyvania | Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same |
| HUE049669T2 (hu) | 2011-02-11 | 2020-10-28 | Univ Pennsylvania | Hepatitis B vírus magfehérjéjét kódoló nukleinsav-molekula és azt tartalmazó oltóanyag |
| EP2694677A2 (en) | 2011-04-04 | 2014-02-12 | Netherland Cancer Institute | Methods and compositions for predicting resistance to anticancer treatment with protein kinase inhibitors |
| AU2012240246A1 (en) | 2011-04-04 | 2013-05-09 | Netherlands Cancer Institute | Methods and compositions for predicting resistance to anticancer treatment with protein kinase inhibitors |
| WO2012145577A1 (en) | 2011-04-20 | 2012-10-26 | Merial Limited | Adjuvanted rabies vaccine with improved viscosity profile |
| JP6407714B2 (ja) | 2011-04-25 | 2018-10-17 | アドヴァンスド バイオサイエンス ラボラトリーズ インコーポレイテッド | 短縮型hivエンベロープタンパク質(env)、前記に関連する方法及び組成物 |
| US9669085B2 (en) | 2011-06-01 | 2017-06-06 | Merial Inc. | Needle-free administration of PRRSV vaccines |
| JP6117781B2 (ja) | 2011-07-11 | 2017-04-19 | イノビオ ファーマシューティカルズ,インコーポレイティド | 交差防御性アレナウイルスワクチンおよびそれらの使用方法 |
| RU2591817C2 (ru) | 2011-07-20 | 2016-07-20 | Мериал Лимитед | Рекомбинантная вакцина вируса лейкемии кошек, содержащая оптимизированный ген оболочки вируса лейкемии кошек |
| ES2626297T3 (es) | 2011-08-12 | 2017-07-24 | Merial, Inc. | Preservación asistida por vacío de productos biológicos, en particular de vacunas |
| AR088028A1 (es) | 2011-08-15 | 2014-05-07 | Boehringer Ingelheim Vetmed | Proteinas h5, de h5n1 para un uso medicinal |
| WO2013033092A2 (en) | 2011-09-03 | 2013-03-07 | Boehringer Ingelheim Vetmedica Gmbh | Streptococcus suis pilus antigens |
| AU2011378812B2 (en) | 2011-10-12 | 2017-08-24 | The Trustees Of The University Of Pennsylvania | Vaccines for human papilloma virus and methods for using the same |
| EP2771035B1 (en) | 2011-10-24 | 2018-04-11 | The Trustees Of The University Of Pennsylvania | Improved hcv vaccines and methods for using the same |
| AU2012352455B2 (en) | 2011-12-12 | 2016-01-21 | The Trustees Of The University Of Pennsylvania | Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections |
| CA2858893A1 (en) | 2011-12-12 | 2013-06-20 | The Trustees Of The University Of Pennsylvania | Compositions, comprising improved il-12 genetic constructs and vaccines, immunotherapeutics and methods of using the same |
| WO2013093629A2 (en) | 2011-12-20 | 2013-06-27 | Netherlands Cancer Institute | Modular vaccines, methods and compositions related thereto |
| WO2013138776A1 (en) | 2012-03-16 | 2013-09-19 | Merial Limited | Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g |
| HUE042396T2 (hu) * | 2012-03-20 | 2019-06-28 | Merial Inc | Mutáns C glikoproteint tartalmazó, rekombináns ló herpeszvírus-1 oltóanyag és alkalmazásai |
| MX363667B (es) | 2012-04-10 | 2019-03-29 | Univ Pennsylvania | Antigenos de consenso del virus sincitial respiratorio humano, constructos de acido nucleico y vacunas hechas de estos, y metodos para utilizarlas. |
| ES2689878T3 (es) | 2013-02-21 | 2018-11-16 | Boehringer Ingelheim Vetmedica Gmbh | Proteínas H5 del virus de la gripe H5N1 para su uso como un medicamento |
| EP2968527A4 (en) | 2013-03-12 | 2016-08-17 | Univ Pennsylvania | IMPROVED VACCINES AGAINST HUMAN PAPILLOMA VIRUS AND METHOD FOR USE THEREOF |
| WO2014164697A1 (en) | 2013-03-12 | 2014-10-09 | Merial Limited | Reverse genetics schmallenberg virus vaccine compositions, and methods of use thereof |
| MX369709B (es) | 2013-03-15 | 2019-11-19 | Univ Pennsylvania | Vacunación mejorada contra tirosinasa. |
| ES2817903T3 (es) | 2013-03-15 | 2021-04-08 | Univ Pennsylvania | Proteínas de consenso del virus de la Fiebre Aftosa (VFA), secuencias codificantes y vacunas preparadas a partir de las mismas |
| EP3125932A1 (en) | 2014-04-03 | 2017-02-08 | Boehringer Ingelheim Vetmedica, Inc. | Porcine epidemic diarrhea virus vaccine |
| EP3215188A1 (en) | 2014-11-03 | 2017-09-13 | Merial, Inc. | Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus |
| AR105482A1 (es) | 2015-06-23 | 2017-10-11 | Merial Inc | Vectores virales recombinantes que contienen la proteína menor del virus del síndrome reproductor y respiratorio porcino (prrsv) y sus métodos de elaboración y uso |
| US9920302B2 (en) | 2015-08-31 | 2018-03-20 | Boehringer Ingelheim Vetmedica Gmbh | Pestivirus vaccines for congenital tremors |
| MX2018003173A (es) | 2015-09-16 | 2018-05-17 | Boehringer Ingelheim Vetmedica Inc | Vacunas de salmonella choleraesuis-salmonella typhimurium. |
| AU2017329672B2 (en) | 2016-09-20 | 2023-07-27 | Boehringer Ingelheim Vetmedica Gmbh | New promoters |
| CA3036310A1 (en) | 2016-09-20 | 2018-03-29 | Boehringer Ingelheim Vetmedica Gmbh | New swine influenza vaccine |
| CN109715204B (zh) | 2016-09-20 | 2023-08-22 | 勃林格殷格翰动物保健有限公司 | 新的ehv插入位点orf70 |
| EA201990718A1 (ru) | 2016-09-20 | 2019-10-31 | Векторы аденовируса собачьих | |
| CN109803678B (zh) | 2016-11-03 | 2023-08-22 | 勃林格殷格翰动物保健有限公司 | 抗猪细小病毒的疫苗 |
| JP6941171B2 (ja) | 2016-11-03 | 2021-09-29 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | ブタパルボウイルスおよびブタ繁殖呼吸障害症候群ウイルスに対するワクチン、ならびにこれらを作製する方法 |
| EP3573655A2 (en) | 2017-01-30 | 2019-12-04 | Boehringer Ingelheim Animal Health USA Inc. | Porcine coronavirus vaccines |
| JP7083362B2 (ja) | 2017-07-12 | 2022-06-10 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | セネカウイルスa免疫原性組成物およびその方法 |
| TW201923084A (zh) | 2017-09-23 | 2019-06-16 | 德商百靈佳殷格翰維美迪加股份有限公司 | 副黏液病毒科(paramyxoviridae)表現系統 |
| WO2019092027A1 (en) | 2017-11-09 | 2019-05-16 | Boehringer Ingelheim Vetmedica Gmbh | Sapelovirus immunogenic compositions and uses thereof |
| MX2020006218A (es) | 2017-12-13 | 2020-08-31 | Inovio Pharmaceuticals Inc | Vacunas contra el cancer dirigidas a boris y sus usos. |
| AU2018383662C1 (en) | 2017-12-13 | 2023-02-09 | Inovio Pharmaceuticals, Inc. | Cancer vaccines targeting MUC16 and uses thereof |
| KR20240024366A (ko) | 2017-12-13 | 2024-02-23 | 이노비오 파마수티컬즈, 인크. | 메소텔린을 표적으로 하는 암 백신 및 이의 용도 |
| CN117264963A (zh) | 2017-12-13 | 2023-12-22 | 艾诺奥医药品有限公司 | 靶向prame的癌症疫苗和其用途 |
| RU2711907C2 (ru) * | 2017-12-22 | 2020-01-23 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова) | Рекомбинантный белок, содержащий антигенно-значимые фрагменты белков вируса гепатита Е, используемый в тест-системах для серодиагностики гепатита Е (варианты) |
| JP2021514196A (ja) | 2018-02-23 | 2021-06-10 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | 外因性ネコパラミクソウイルス遺伝子を発現する組換えウイルスベクター系およびそれらから製作されるワクチン |
| US11384365B2 (en) | 2018-03-19 | 2022-07-12 | Boehringer Ingelheim Vetmedica Gmbh | EHV with inactivated UL18 and/or UL8 |
| CA3091960A1 (en) | 2018-03-19 | 2019-09-26 | Boehringer Ingelheim Vetmedica Gmbh | New ehv insertion site ul43 |
| CN119488586A (zh) | 2018-03-26 | 2025-02-21 | 勃林格殷格翰动物保健美国有限公司 | 制备免疫原性组合物的方法 |
| WO2020058327A1 (en) | 2018-09-20 | 2020-03-26 | Boehringer Ingelheim Vetmedica Gmbh | Modified pedv spike protein |
| TW202026010A (zh) | 2018-09-20 | 2020-07-16 | 德商百靈佳殷格翰維美迪加股份有限公司 | 抗豬流行性下痢之鼻內載體疫苗 |
| EP4100420A1 (en) | 2020-02-06 | 2022-12-14 | Boehringer Ingelheim Vetmedica GmbH | Polypeptides useful for detecting anti-rhabdovirus antibodies |
| EP4225776A1 (en) | 2020-10-05 | 2023-08-16 | Boehringer Ingelheim Vetmedica GmbH | Fusion protein useful for vaccination against rotavirus |
| CN116438202A (zh) | 2020-10-05 | 2023-07-14 | 勃林格殷格翰动物保健美国有限公司 | 包含圆环病毒科衣壳蛋白的融合蛋白及其构成的嵌合病毒样颗粒 |
| EP4504251A1 (en) | 2022-04-05 | 2025-02-12 | Boehringer Ingelheim Vetmedica GmbH | Immunogenic composition useful for vaccination against rotavirus |
| WO2025184411A1 (en) | 2024-02-27 | 2025-09-04 | Calidi Biotherapeutics (Nevada), Inc. | Serum-resistant eev viruses and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1061898A (en) | 1963-03-07 | 1967-03-15 | Philips Electronic Pharma | Method for protecting dogs against canine distemper |
| US4769330A (en) * | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
| US4722848A (en) * | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4603112A (en) * | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| JPH0795954B2 (ja) * | 1982-11-30 | 1995-10-18 | アメリカ合衆国 | 外来性遺伝子発現のためのポックスウイルス組換え体の製造方法 |
| EP0162738A1 (en) | 1984-04-09 | 1985-11-27 | MOLECULAR GENETICS RESEARCH & DEVELOPMENT LIMITED PARTNERSHIP | Production of pseudorabies virus subunit vaccines |
| EP0261940A3 (en) * | 1986-09-23 | 1989-07-05 | Applied Biotechnology, Inc. | Pseudorabies vaccines and dna vectors for recombination with pox viruses |
| US5242829A (en) * | 1986-09-23 | 1993-09-07 | Therion Biologics Corporation | Recombinant pseudorabies virus |
| AU605567B2 (en) * | 1987-03-11 | 1991-01-17 | Nippon Zeon Co., Ltd. | Recombinant avipoxvirus |
| EP0297924A3 (en) * | 1987-07-01 | 1990-07-11 | City Of Hope | Recombinant vaccinia virus expressing hsv 1 gb |
| DE10399032I1 (de) * | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
| WO1990001546A1 (en) * | 1988-08-05 | 1990-02-22 | Applied Biotechnology, Inc. | Equine herpesvirus-1 vaccine |
| IE71643B1 (en) | 1990-11-20 | 1997-02-26 | Virogenetics Corp | A recombinant poxviral vaccine for canine distemper |
-
1990
- 1990-04-04 US US07/502,834 patent/US5338683A/en not_active Expired - Lifetime
- 1990-04-12 CA CA002014465A patent/CA2014465C/en not_active Expired - Lifetime
- 1990-04-16 WO PCT/US1990/002094 patent/WO1990012882A1/en active Application Filing
- 1990-04-16 AU AU55520/90A patent/AU625623B2/en not_active Expired
- 1990-04-16 KR KR1019900702630A patent/KR920700289A/ko not_active Withdrawn
- 1990-04-16 NL NL9020677A patent/NL195016C/nl not_active IP Right Cessation
- 1990-04-16 JP JP02507078A patent/JP3083839B2/ja not_active Expired - Lifetime
- 1990-04-16 CH CH3982/90A patent/CH682671A5/fr not_active IP Right Cessation
- 1990-04-16 DE DE4090565A patent/DE4090565C2/de not_active Expired - Lifetime
- 1990-04-16 AT AT0902590A patent/AT405184B/de active
- 1990-04-16 DE DE19904090565 patent/DE4090565T/de active Pending
- 1990-04-17 BE BE9000425A patent/BE1004369A5/fr not_active IP Right Cessation
- 1990-04-17 IT IT20063A patent/IT1241119B/it active IP Right Grant
- 1990-04-17 FR FR9004910A patent/FR2647808B1/fr not_active Expired - Lifetime
- 1990-04-18 IE IE138090A patent/IE61098B1/en not_active IP Right Cessation
-
1991
- 1991-09-27 GB GB9120655A patent/GB2246784B/en not_active Expired - Lifetime
- 1991-10-15 DK DK199101743A patent/DK176464B1/da not_active IP Right Cessation
- 1991-10-16 LU LU88018A patent/LU88018A1/fr unknown
-
1993
- 1993-09-21 US US08/124,668 patent/US5482713A/en not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/476,500 patent/US6183750B1/en not_active Expired - Lifetime
-
1999
- 1999-12-28 JP JP37276499A patent/JP3246735B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR920700289A (ko) | 허피스바이러스 재조합 천연두바이러스 백신 | |
| Zuckermann et al. | Complex between glycoproteins gI and gp63 of pseudorabies virus: its effect on virus replication | |
| Fuchs et al. | Molecular biology of avian infectious laryngotracheitis virus | |
| CA2031164A1 (en) | Recombinant herpesvirus of turkeys and live vector vaccines derived thereof | |
| KR890701757A (ko) | 재조합 아비폭스 바이러스 | |
| GEP20084431B (en) | Papilloma virus vaccine | |
| Osborn | Cytomegalovirus and other herpesviruses | |
| Haslam et al. | The structural proteins of Newcastle disease virus | |
| EP0261940A3 (en) | Pseudorabies vaccines and dna vectors for recombination with pox viruses | |
| Plummer et al. | Equine herpesviruses: antigenic relationships and deoxyribonucleic acid densities | |
| Pay et al. | Production of rabies vaccine by an industrial scale BHK 21 suspension cell culture process | |
| DE3775321D1 (de) | Verfahren zur kultur des virus der rhinotracheitis des truthahnes und daraus hergestelltes vakzin. | |
| ATE73349T1 (de) | Hepatitisoberflaechenantigenpartikelvakzin. | |
| BR9303226A (pt) | Processo e vacina para produzir anticorpos ou imundade mediada por celulas e adenovirus recombinante | |
| DE3888290D1 (de) | Mutanten des infektiösen bovinen Rhinotracheitisvirus, Vakzine die sie enthalten, Verfahren zu ihrer Herstellung und ihrer Verwendung. | |
| Cook et al. | Protection against lethal equine herpes virus type 1 (subtype 1) infection in hamsters by immune stimulating complexes (ISCOMs) containing the major viral glycoproteins | |
| IL110560A0 (en) | Recombinant adenovirus vaccines | |
| VIROLOGY | DEVELOPMENTS IN VETERINARY VIROLOGY | |
| Love et al. | Characterization of the glycoprotein D gene products of equine herpesvirus 1 using a prokaryotic cell expression vector | |
| ATE173760T1 (de) | Verfahren zur herstellung von lebenden zellkulturen, die durch einen multiple sklerose assoziierten virus infiziert sind | |
| Sheppard | Viral vectors for veterinary vaccines | |
| DK0606452T3 (da) | Vektorvacciner fra rekombinant katteherpesvirus | |
| Blue et al. | Antigenic relationships among four herpesviruses | |
| ZA874434B (en) | Varicella-zoster virus as a live recombinant vaccine | |
| KR20230050444A (ko) | 공동-자극 분자를 발현하는 재조합 폭스비리대 벡터 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19901217 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |