KR20150061041A - 인간 ｏｘ４０ 수용체에 대한 결합 분자 - Google Patents

인간 ｏｘ４０ 수용체에 대한 결합 분자 Download PDF

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Publication number
KR20150061041A
KR20150061041A KR1020157013715A KR20157013715A KR20150061041A KR 20150061041 A KR20150061041 A KR 20150061041A KR 1020157013715 A KR1020157013715 A KR 1020157013715A KR 20157013715 A KR20157013715 A KR 20157013715A KR 20150061041 A KR20150061041 A KR 20150061041A
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antibody
ox40r
human
ser
cells
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Ceased
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English (en)
Korean (ko)
Inventor
징 민
얀리 유
로리 프란시스 핀
바레트 리차드 틸
웨이 리아오
로날드 폴 글레이듀
아빈드 라즈펄
티모시 조세프 파라디스
페터 브람스
브리지트 드벅스
이 유
크리스토퍼 토이
하이디 엔. 레블란크
하이춘 후앙
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브리스톨-마이어스 스큅 컴퍼니
화이자 인코포레이티드
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Application filed by 브리스톨-마이어스 스큅 컴퍼니, 화이자 인코포레이티드 filed Critical 브리스톨-마이어스 스큅 컴퍼니
Publication of KR20150061041A publication Critical patent/KR20150061041A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020157013715A 2007-12-14 2008-12-11 인간 ｏｘ４０ 수용체에 대한 결합 분자 Ceased KR20150061041A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1394707P 2007-12-14 2007-12-14
US61/013,947 2007-12-14
PCT/US2008/086417 WO2009079335A1 (en) 2007-12-14 2008-12-11 Binding molecules to the human ox40 receptor

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020107015527A Division KR101577843B1 (ko) 2007-12-14 2008-12-11 인간 ｏｘ４０ 수용체에 대한 결합 분자

Publications (1)

Publication Number Publication Date
KR20150061041A true KR20150061041A (ko) 2015-06-03

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ID=40552119

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KR1020157013715A Ceased KR20150061041A (ko) 2007-12-14 2008-12-11 인간 ｏｘ４０ 수용체에 대한 결합 분자
KR1020107015527A Expired - Fee Related KR101577843B1 (ko) 2007-12-14 2008-12-11 인간 ｏｘ４０ 수용체에 대한 결합 분자

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KR1020107015527A Expired - Fee Related KR101577843B1 (ko) 2007-12-14 2008-12-11 인간 ｏｘ４０ 수용체에 대한 결합 분자

Country Status (29)

Country Link
US (7) US7960515B2 (https=)
EP (4) EP3239178A1 (https=)
JP (4) JP5761997B2 (https=)
KR (2) KR20150061041A (https=)
CN (1) CN101918447B (https=)
AR (2) AR069681A1 (https=)
AU (1) AU2008338591B8 (https=)
BR (1) BRPI0820875B1 (https=)
CA (2) CA2707773C (https=)
CL (1) CL2008003706A1 (https=)
CO (1) CO6280541A2 (https=)
DK (3) DK2851374T3 (https=)
ES (3) ES2425269T3 (https=)
HR (1) HRP20141188T8 (https=)
HU (1) HUE032735T2 (https=)
IL (3) IL206297A (https=)
MX (1) MX2010006466A (https=)
PA (1) PA8807601A1 (https=)
PE (1) PE20091269A1 (https=)
PH (1) PH12015500806B1 (https=)
PL (2) PL2242771T3 (https=)
PT (3) PT2594590E (https=)
RU (1) RU2010129045A (https=)
SG (2) SG10201604770VA (https=)
SI (3) SI2851374T1 (https=)
TW (1) TW200932268A (https=)
UY (1) UY31533A1 (https=)
WO (1) WO2009079335A1 (https=)
ZA (1) ZA201003579B (https=)

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