KR102012113B1 - 항-pd-1 항체 및 그의 사용 방법 - Google Patents

항-pd-1 항체 및 그의 사용 방법 Download PDF

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KR102012113B1
KR102012113B1 KR1020177018639A KR20177018639A KR102012113B1 KR 102012113 B1 KR102012113 B1 KR 102012113B1 KR 1020177018639 A KR1020177018639 A KR 1020177018639A KR 20177018639 A KR20177018639 A KR 20177018639A KR 102012113 B1 KR102012113 B1 KR 102012113B1
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seq
amino acid
acid sequence
antibody
cancer
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KR20170086662A (ko
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야스미나 노우비아 아브디체
헬렌 킴 조
웨이셴 호
카린 우테 주스
아르빈드 라즈팔
소산 유세프
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리나트 뉴로사이언스 코프.
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K2039/507—Comprising a combination of two or more separate antibodies
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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KR1020177018639A 2014-12-09 2015-12-02 항-pd-1 항체 및 그의 사용 방법 Active KR102012113B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462089658P 2014-12-09 2014-12-09
US62/089,658 2014-12-09
US201562242750P 2015-10-16 2015-10-16
US62/242,750 2015-10-16
US201562251973P 2015-11-06 2015-11-06
US62/251,973 2015-11-06
PCT/IB2015/059268 WO2016092419A1 (en) 2014-12-09 2015-12-02 Anti-pd-1 antibodies and methods of use thereof

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KR20170086662A KR20170086662A (ko) 2017-07-26
KR102012113B1 true KR102012113B1 (ko) 2019-08-19

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US (4) US10155037B2 (enExample)
EP (2) EP3230319B8 (enExample)
JP (1) JP6552621B2 (enExample)
KR (1) KR102012113B1 (enExample)
CN (1) CN107207593B (enExample)
AU (2) AU2015359003B2 (enExample)
CA (1) CA2914087C (enExample)
CO (1) CO2017005738A2 (enExample)
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ES (1) ES2929721T3 (enExample)
HR (1) HRP20221226T1 (enExample)
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