JPS6210512B2 - - Google Patents

Info

Publication number
JPS6210512B2
JPS6210512B2 JP55132253A JP13225380A JPS6210512B2 JP S6210512 B2 JPS6210512 B2 JP S6210512B2 JP 55132253 A JP55132253 A JP 55132253A JP 13225380 A JP13225380 A JP 13225380A JP S6210512 B2 JPS6210512 B2 JP S6210512B2
Authority
JP
Japan
Prior art keywords
acid
group
amino
methyl
carboxyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP55132253A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5758689A (en
Inventor
Hiroshi Sadaki
Hirokazu Narita
Hiroyuki Imaizumi
Yoshinori Konishi
Takihiro Inaba
Tatsuo Hirakawa
Hideo Taki
Masaru Tai
Yasuo Watanabe
Isamu Saikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP55132253A priority Critical patent/JPS5758689A/ja
Priority to NZ198350A priority patent/NZ198350A/en
Priority to CA000386066A priority patent/CA1204735A/en
Priority to PH26215A priority patent/PH18072A/en
Priority to GB8128011A priority patent/GB2089339B/en
Priority to AU75438/81A priority patent/AU550330B2/en
Priority to IN1045/CAL/81A priority patent/IN155375B/en
Priority to IL74415A priority patent/IL74415A/xx
Priority to ZA816576A priority patent/ZA816576B/xx
Priority to DE3152931A priority patent/DE3152931C2/de
Priority to US06/304,912 priority patent/US4489072A/en
Priority to DE3152934A priority patent/DE3152934C2/de
Priority to PL1981238228A priority patent/PL137674B1/pl
Priority to IT49348/81A priority patent/IT1172201B/it
Priority to DE3152932A priority patent/DE3152932C2/de
Priority to NL8104386A priority patent/NL8104386A/xx
Priority to DE3152935A priority patent/DE3152935C2/de
Priority to DE19813137854 priority patent/DE3137854A1/de
Priority to DK421881A priority patent/DK163877C/da
Priority to SE8105658A priority patent/SE453090B/sv
Priority to FI812980A priority patent/FI75575C/fi
Priority to MX7609A priority patent/MX155025A/es
Priority to ES505760A priority patent/ES8301998A1/es
Priority to HU831798A priority patent/HU188021B/hu
Priority to AT0410981A priority patent/AT375082B/de
Priority to LU83650A priority patent/LU83650A1/fr
Priority to NO813252A priority patent/NO161117C/no
Priority to HU812759A priority patent/HU185850B/hu
Priority to KR1019810003579A priority patent/KR860000487B1/ko
Priority to PT73727A priority patent/PT73727B/pt
Priority to RO112112A priority patent/RO86824B/ro
Priority to RO112113A priority patent/RO86825B/ro
Priority to RO112111A priority patent/RO86823B/ro
Priority to BE0/206067A priority patent/BE890499A/fr
Priority to CH4521/84A priority patent/CH652128A5/de
Priority to CH6202/81A priority patent/CH652129A5/de
Priority to CH4520/84A priority patent/CH652130A5/de
Priority to FR8118156A priority patent/FR2509310B1/fr
Priority to DD81247292A priority patent/DD208351A5/de
Priority to RO81105405A priority patent/RO82689A/ro
Priority to DD81233599A priority patent/DD202436A5/de
Priority to CH4519/84A priority patent/CH651837A5/de
Priority to EG543/81A priority patent/EG17373A/xx
Publication of JPS5758689A publication Critical patent/JPS5758689A/ja
Priority to ES514669A priority patent/ES8306155A1/es
Priority to ES514670A priority patent/ES514670A0/es
Priority to ES514671A priority patent/ES514671A0/es
Priority to FR8215992A priority patent/FR2511377B1/fr
Priority to FR8215995A priority patent/FR2511374B1/fr
Priority to FR8215994A priority patent/FR2511373B1/fr
Priority to CS827531A priority patent/CS236493B2/cs
Priority to SU823520352A priority patent/SU1308198A3/ru
Priority to SU823521951A priority patent/SU1318144A3/ru
Priority to AR29180883A priority patent/AR240645A1/es
Priority to AT0055483A priority patent/AT378961B/de
Priority to AT0055583A priority patent/AT378962B/de
Priority to AT0055683A priority patent/AT378193B/de
Priority to PH29075A priority patent/PH19251A/en
Priority to PH29077A priority patent/PH20221A/en
Priority to PH29076A priority patent/PH19147A/en
Priority to PH29078A priority patent/PH18484A/en
Priority to SU833635254A priority patent/SU1350166A1/ru
Priority to CA000435930A priority patent/CA1200541A/en
Priority to GB838333402A priority patent/GB8333402D0/en
Priority to GB838333401A priority patent/GB8333401D0/en
Priority to GB08402249A priority patent/GB2135304B/en
Priority to GB08402250A priority patent/GB2136420B/en
Priority to IN601/CAL/84A priority patent/IN158589B/en
Priority to IN602/CAL/84A priority patent/IN158590B/en
Priority to IN603/CAL/84A priority patent/IN159126B/en
Priority to US06/654,681 priority patent/US4673738A/en
Priority to IL74415A priority patent/IL74415A0/xx
Priority to IL76348A priority patent/IL76348A0/xx
Priority to AU49861/85A priority patent/AU568033B2/en
Priority to AU49860/85A priority patent/AU558586B2/en
Priority to AU49862/85A priority patent/AU558649B2/en
Priority to AU49863/85A priority patent/AU558669B2/en
Priority to SE8600193A priority patent/SE468479B/sv
Priority to SE8600194A priority patent/SE468476B/sv
Priority to SE8600192A priority patent/SE468478B/sv
Priority to SE8600195A priority patent/SE468477B/sv
Priority to MX904686A priority patent/MX9046A/es
Priority to KR1019860002383A priority patent/KR860000932B1/ko
Priority to FI870153A priority patent/FI80041C/fi
Priority to US07/022,433 priority patent/US4879381A/en
Publication of JPS6210512B2 publication Critical patent/JPS6210512B2/ja
Priority to US07/707,221 priority patent/US5144027A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP55132253A 1980-09-25 1980-09-25 Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids Granted JPS5758689A (en)

Priority Applications (85)

Application Number Priority Date Filing Date Title
JP55132253A JPS5758689A (en) 1980-09-25 1980-09-25 Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids
NZ198350A NZ198350A (en) 1980-09-25 1981-09-14 Cephalosporins and intermediates;pharmaceutical compositions
CA000386066A CA1204735A (en) 1980-09-25 1981-09-16 Cephalosporins, processes for producing the same, intermediates thereof and process for producing the intermediates
PH26215A PH18072A (en) 1980-09-25 1981-09-16 Cephalosporins
GB8128011A GB2089339B (en) 1980-09-25 1981-09-16 Novel cephalosporins processes for producing the same intermediates thereof and process for producing the intermediates
AU75438/81A AU550330B2 (en) 1980-09-25 1981-09-17 Cephalosporin derivatives with a broad antibacterial spectrum 276
IN1045/CAL/81A IN155375B (pt) 1980-09-25 1981-09-19
IL74415A IL74415A (en) 1980-09-25 1981-09-20 7-(substituted or unsubstituted amino)-3-substituted methyl-delta3-cephem-4-carboxylic acids
ZA816576A ZA816576B (en) 1980-09-25 1981-09-22 Cephalosporins,processes for producing same,intermediates thereof and process for producing the intermediates
DE3152931A DE3152931C2 (pt) 1980-09-25 1981-09-23
US06/304,912 US4489072A (en) 1980-09-25 1981-09-23 Cephalosporins
DE3152934A DE3152934C2 (pt) 1980-09-25 1981-09-23
PL1981238228A PL137674B1 (en) 1980-09-25 1981-09-23 Method of obtaining derivatives of delta 3-cephemocarboxylic acid
IT49348/81A IT1172201B (it) 1980-09-25 1981-09-23 Cefalosporine e loro intermedi relativo procentimento di poduzione e composizioni farmaceutiche che le contengono
DE3152932A DE3152932C2 (pt) 1980-09-25 1981-09-23
NL8104386A NL8104386A (nl) 1980-09-25 1981-09-23 Cefalosporinen, werkwijzen ter bereiding daarvan, tussenproducten daarvan, werkwijze ter bereiding van de tussenproducten, alsmede farmaceutische preparaten die de cefalosporinen als actieve component bevatten.
DE3152935A DE3152935C2 (pt) 1980-09-25 1981-09-23
DE19813137854 DE3137854A1 (de) 1980-09-25 1981-09-23 Neue cephalosporine, verfahren zur herstellung derselben, zwischenstufen derselben und verfahren zur herstellung der zwischenstufen
DK421881A DK163877C (da) 1980-09-25 1981-09-24 Analogifremgangsmaade til fremstilling af hidtil ukendte cephalosporiner
SE8105658A SE453090B (sv) 1980-09-25 1981-09-24 Nya cefalosporinderivat, forfarande for framstellning derav samt farmaceutisk komposition derav
FI812980A FI75575C (fi) 1980-09-25 1981-09-24 Foerfarande foer framstaellning av nya cefalosporiner.
MX7609A MX155025A (es) 1980-09-25 1981-09-24 Procedimiento para producir cefalosporinas
ES505760A ES8301998A1 (es) 1980-09-25 1981-09-24 Un procedimiento para la produccion de nuevas cefalosporinas.
HU831798A HU188021B (en) 1980-09-25 1981-09-24 Process for preparing 7-amino-3-substituted methyl-cef-3-em-carboxylic acids
AT0410981A AT375082B (de) 1980-09-25 1981-09-24 Verfahren zur herstellung von neuen cephalosporinen
LU83650A LU83650A1 (fr) 1980-09-25 1981-09-24 Nouvelles cephalosporines,leur procede de preparation et leur application en therapeutique
NO813252A NO161117C (no) 1980-09-25 1981-09-24 Analogifremgangsmaate for fremstilling av terapeutisk aktive cefalosporinderivater.
HU812759A HU185850B (en) 1980-09-25 1981-09-24 Process for preparing 7-/ /thiazol-4-yl/-acetamido- or hydroxy-imino- or alkoxy-imino-acetamido/ -delta up 3 -cefem-4-carboxylic acid derivatives
KR1019810003579A KR860000487B1 (ko) 1980-09-25 1981-09-24 세팔로스포린의 제조방법
PT73727A PT73727B (en) 1980-09-25 1981-09-24 Novel cephalosporins processes for producing the same intermediates thereof and process for producing the inter- mediates
RO112112A RO86824B (ro) 1980-09-25 1981-09-25 Procedeu pentru prepararea unor cefalosporine
RO112113A RO86825B (ro) 1980-09-25 1981-09-25 Procedeu pentru prepararea unor acizi 7-amino-3-metil-substituit-delta3-cefem-4-carboxilici
RO112111A RO86823B (ro) 1980-09-25 1981-09-25 Procedeu pentru prepararea unor cefalosporine
BE0/206067A BE890499A (fr) 1980-09-25 1981-09-25 Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
CH4521/84A CH652128A5 (de) 1980-09-25 1981-09-25 Zwischenprodukte zur herstellung von neuen cephalosporinen und verfahren zur herstellung derselben.
CH6202/81A CH652129A5 (de) 1980-09-25 1981-09-25 Neue cephalosporine, verfahren zur herstellung derselben.
CH4520/84A CH652130A5 (de) 1980-09-25 1981-09-25 Zwischenprodukte zur herstellung von neuen cephalosporinen.
FR8118156A FR2509310B1 (fr) 1980-09-25 1981-09-25 Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
DD81247292A DD208351A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung eines 7-(subst.-oder unsubst.-amiono)-3-(subst.-methyl)-delta hoch 3-cephem-4-carbonsaeure
RO81105405A RO82689A (ro) 1980-09-25 1981-09-25 Procedeu pentru prepararea unor cefalosporine
DD81233599A DD202436A5 (de) 1980-09-25 1981-09-25 Verfahren zur herstellung von neuen cephalosporinen
CH4519/84A CH651837A5 (de) 1980-09-25 1981-09-25 Zwischenprodukte zur herstellung von neuen cephalosporinen.
EG543/81A EG17373A (en) 1980-09-25 1981-09-26 Novel cephalosporins process for production the same intermediates thereof and process for producting the intermediates
ES514669A ES8306155A1 (es) 1980-09-25 1982-08-02 Un procedimiento para la produccion de nuevas cefalosporinas.
ES514670A ES514670A0 (es) 1980-09-25 1982-08-02 Un procedimiento para la produccion de nuevas cefalosporinas.
ES514671A ES514671A0 (es) 1980-09-25 1982-08-02 Un procedimiento para la produccion de un acido 7-(amino sustituido o no sustituido)-3-metil sustituido-a3-cefem-4-carboxilico.
FR8215992A FR2511377B1 (fr) 1980-09-25 1982-09-22 Nouvelles cephalosporines, et leurs sels
FR8215995A FR2511374B1 (fr) 1980-09-25 1982-09-22 Procede de preparation des acides 7-(amino substitue ou non)-3-methyl substitue-3-cepheme-4 carboxyliques
FR8215994A FR2511373B1 (fr) 1980-09-25 1982-09-22 Acides 7-(amino substitue ou non)-3-methyl substitue-3-cepheme-4-carboxyliques
CS827531A CS236493B2 (en) 1980-09-25 1982-10-22 Method of 7-amino-3-substituted methyl-delta 3-cephem-4-carboxyl acid's preparation
SU823520352A SU1308198A3 (ru) 1980-09-25 1982-12-09 Способ получени 7-амино-3-замещенной метил- @ -цефем-4-карбоновой кислоты или ее кислотно-аддитивных солей
SU823521951A SU1318144A3 (ru) 1980-09-25 1982-12-09 Способ получени производных цефалоспорина или их солей
AR29180883A AR240645A1 (es) 1980-09-25 1983-01-07 Un procedimiento para producir novedosas cefalospirinas
AT0055483A AT378961B (de) 1980-09-25 1983-02-18 Verfahren zur herstellung von neuen cephalosporinen
AT0055583A AT378962B (de) 1980-09-25 1983-02-18 Verfahren zur herstellung von neuen cephalosporinen
AT0055683A AT378193B (de) 1980-09-25 1983-02-18 Verfahren zur herstellung von 7-(substituierten oder unsubstituierten amino)-3-(substituierten methyl)-delta3-cephem-4-carbonsaeuren
PH29075A PH19251A (en) 1980-09-25 1983-06-17 Process for producing novel cephalosporin
PH29077A PH20221A (en) 1980-09-25 1983-06-17 Process for producing novel cephalosporins
PH29076A PH19147A (en) 1980-09-25 1983-06-17 Process for producing novel cephalosporin
PH29078A PH18484A (en) 1980-09-25 1983-06-17 Process for producing novel cephalosporins
SU833635254A SU1350166A1 (ru) 1980-09-25 1983-08-24 7-Амино-3-замещенный метил- @ -цефем-4-карбонова кислота в качестве промежуточных продуктов в синтезе 7-ациламидоцефалоспоринов,про вл ющих антибактериальные свойства
CA000435930A CA1200541A (en) 1980-09-25 1983-09-01 Cephalosporins, processes for producing the same, intermediates thereof and process for producing the intermediates
GB838333402A GB8333402D0 (en) 1980-09-25 1983-12-15 Cephalosporins intermediates
GB838333401A GB8333401D0 (en) 1980-09-25 1983-12-15 Cephalosporins intermediates
GB08402249A GB2135304B (en) 1980-09-25 1984-01-27 7-amino-3-(triazolyl or tetrazolyl)methyl-.3-cephem-4-carboxylic acidss
GB08402250A GB2136420B (en) 1980-09-25 1984-01-27 Cephalosporin derivatives
IN601/CAL/84A IN158589B (pt) 1980-09-25 1984-08-29
IN602/CAL/84A IN158590B (pt) 1980-09-25 1984-08-29
IN603/CAL/84A IN159126B (pt) 1980-09-25 1984-08-29
US06/654,681 US4673738A (en) 1980-09-25 1984-09-26 Novel intermediates of cephalosporins and process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl-Δ3 -cephem-4-carboxylic acids
IL74415A IL74415A0 (en) 1980-09-25 1985-02-21 7-(substituted or unsubstituted amino)-3-substituted methyl-delta3-cephem-4-carboxylic acids and a process for producing the same
IL76348A IL76348A0 (en) 1980-09-25 1985-09-10 Process for producing 7-(substituted or unsubstituted amino)-3-substituted methyl delta3-cephem-4-carboxylic acids
AU49861/85A AU568033B2 (en) 1980-09-25 1985-11-13 3-((1,2,4-triazolyl or 2 (1,2,3,4-tetrazolyl) methyl) cephalosporins
AU49860/85A AU558586B2 (en) 1980-09-25 1985-11-13 Cephalosporin derivatives
AU49862/85A AU558649B2 (en) 1980-09-25 1985-11-13 Preparation of 7-amino-3-triazolyl or tetrazolylmethylcephem -4- carboxylic acid derivatives
AU49863/85A AU558669B2 (en) 1980-09-25 1985-11-13 Cephalosporin derivatives
SE8600193A SE468479B (sv) 1980-09-25 1986-01-16 Nya cefalosporinderivat vilka aer anvaendbara som intermediat
SE8600194A SE468476B (sv) 1980-09-25 1986-01-16 Nya 7-(substituerade eller osubstituerade amino)-3- substituerad metyl- -cefem-4-karboxylsyror
SE8600192A SE468478B (sv) 1980-09-25 1986-01-16 Nya cefalosporinderivat vilka aer anvaendbara som intermediat
SE8600195A SE468477B (sv) 1980-09-25 1986-01-16 Foerfarande foer framstaellning av 7-amino-3-substituerad cefalosporinsyra
MX904686A MX9046A (es) 1980-09-25 1986-03-19 Metodo para producir cefalosporinas.
KR1019860002383A KR860000932B1 (ko) 1980-09-25 1986-03-29 7-아미노-3-치환된 메틸-△³-세펨-4-카복실산의 제조방법
FI870153A FI80041C (fi) 1980-09-25 1987-01-15 Foerfarande foer framstaellning av 7-amino-3-(substituerad metyl)- 3 -cefem-4-karboxylsyror.
US07/022,433 US4879381A (en) 1980-09-25 1987-03-06 7-(substituted or unsubstituted amino) 3-substituted methyl-3 cephem-4-carboxylic acid
US07/707,221 US5144027A (en) 1980-09-25 1991-05-24 Cephalosporins, process for producing the same, intermediates thereof and process for producing the intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55132253A JPS5758689A (en) 1980-09-25 1980-09-25 Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids

Publications (2)

Publication Number Publication Date
JPS5758689A JPS5758689A (en) 1982-04-08
JPS6210512B2 true JPS6210512B2 (pt) 1987-03-06

Family

ID=15076944

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55132253A Granted JPS5758689A (en) 1980-09-25 1980-09-25 Novel preparation of 7-substituted or unsubstituted amino-3-substituted methylcephem carboxylic acids

Country Status (10)

Country Link
JP (1) JPS5758689A (pt)
AU (2) AU558669B2 (pt)
BE (1) BE890499A (pt)
CS (1) CS236493B2 (pt)
GB (2) GB8333401D0 (pt)
HU (1) HU188021B (pt)
MX (1) MX9046A (pt)
PL (1) PL137674B1 (pt)
SU (3) SU1308198A3 (pt)
ZA (1) ZA816576B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0390112U (pt) * 1989-12-29 1991-09-13

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0390112U (pt) * 1989-12-29 1991-09-13

Also Published As

Publication number Publication date
AU558586B2 (en) 1987-02-05
SU1318144A3 (ru) 1987-06-15
CS236493B2 (en) 1985-05-15
AU4986085A (en) 1986-03-20
AU558669B2 (en) 1987-02-05
ZA816576B (en) 1982-09-29
BE890499A (fr) 1982-03-25
GB8333402D0 (en) 1984-01-25
MX9046A (es) 1994-02-28
PL238228A1 (en) 1983-05-23
JPS5758689A (en) 1982-04-08
HU188021B (en) 1986-03-28
AU4986385A (en) 1986-03-20
SU1308198A3 (ru) 1987-04-30
SU1350166A1 (ru) 1987-11-07
GB8333401D0 (en) 1984-01-25
PL137674B1 (en) 1986-07-31

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