JPS5877867A - ピリダジンのアミノ誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤 - Google Patents
ピリダジンのアミノ誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤Info
- Publication number
- JPS5877867A JPS5877867A JP57137832A JP13783282A JPS5877867A JP S5877867 A JPS5877867 A JP S5877867A JP 57137832 A JP57137832 A JP 57137832A JP 13783282 A JP13783282 A JP 13783282A JP S5877867 A JPS5877867 A JP S5877867A
- Authority
- JP
- Japan
- Prior art keywords
- group
- carbon atoms
- pyridazine
- general formula
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8115380A FR2510998B1 (fr) | 1981-08-07 | 1981-08-07 | Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent |
| FR8115380 | 1981-08-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5877867A true JPS5877867A (ja) | 1983-05-11 |
| JPH0459312B2 JPH0459312B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-09-21 |
Family
ID=9261294
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57137832A Granted JPS5877867A (ja) | 1981-08-07 | 1982-08-06 | ピリダジンのアミノ誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤 |
| JP57137833A Pending JPS5877868A (ja) | 1981-08-07 | 1982-08-06 | ピリダジン誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57137833A Pending JPS5877868A (ja) | 1981-08-07 | 1982-08-06 | ピリダジン誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤 |
Country Status (30)
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2540113A1 (fr) * | 1983-01-27 | 1984-08-03 | Sanofi Sa | Acides derives de la pyridazine actifs sur le systeme nerveux central |
| US4565814A (en) * | 1983-01-28 | 1986-01-21 | Sanofi | Pyridazine derivatives having a psychotropic action and compositions |
| US4628088A (en) * | 1984-07-17 | 1986-12-09 | Eli Lilly And Company | Preparation of substituted pyridazines |
| DE3664772D1 (en) * | 1985-01-14 | 1989-09-07 | Boehringer Ingelheim Kg | 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use |
| US5461053A (en) * | 1989-02-07 | 1995-10-24 | Sanofi | Pyridazine derivatives |
| US5656631A (en) * | 1989-02-07 | 1997-08-12 | Sanofi | Pyridazine derivatives |
| FR2642754B1 (fr) * | 1989-02-07 | 1991-05-24 | Sanofi Sa | Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant |
| FR2654727B1 (fr) * | 1989-11-17 | 1992-03-27 | Sanofi Sa | Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant. |
| FR2642648B1 (fr) * | 1989-02-07 | 1991-06-21 | Sanofi Sa | Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique |
| FR2665442B1 (fr) * | 1990-07-31 | 1992-12-04 | Sanofi Sa | Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant. |
| FR2663326B2 (fr) * | 1989-11-17 | 1992-10-16 | Sanofi Sa | Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant. |
| PT93060B (pt) | 1989-02-07 | 1995-12-29 | Sanofi Sa | Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem |
| FR2676444B1 (fr) * | 1991-05-16 | 1995-03-10 | Sanofi Elf | Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant. |
| US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
| WO2003018563A1 (en) * | 2001-08-31 | 2003-03-06 | Northwestern University | Anti-inflammatory and protein kinase inhibitor composition and method of use |
| ATE420867T1 (de) * | 2002-08-13 | 2009-01-15 | Merck Sharp & Dohme | Phenylpyridazin derivative als liganden für gaba- rezeptoren |
| US8367672B2 (en) | 2004-11-02 | 2013-02-05 | Universite De Strasbourg | Pyridazine compounds, compositions and methods |
| EP1812007B1 (en) * | 2004-11-02 | 2011-09-07 | Northwestern University | Pyridazine compounds and methods |
| US8158627B2 (en) * | 2006-04-28 | 2012-04-17 | Northwestern University | Compositions and treatments using pyridazine compounds and cholinesterase inhibitors |
| EP2015751A2 (en) * | 2006-04-28 | 2009-01-21 | Northwestern University | Salts of pyridazine compounds |
| EP2063894B1 (en) | 2006-04-28 | 2019-08-28 | Northwestern University | Formulations containing pyridazine compounds for treating neuroinflammatory diseases |
| RU2555969C1 (ru) * | 2014-07-09 | 2015-07-10 | Юлия Алексеевна Щепочкина | Керамическая масса для изготовления облицовочной плитки |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
-
1981
- 1981-08-07 FR FR8115380A patent/FR2510998B1/fr not_active Expired
-
1982
- 1982-07-21 NO NO822509A patent/NO157861C/no unknown
- 1982-07-21 NO NO822510A patent/NO157102C/no unknown
- 1982-07-23 IE IE1779/82A patent/IE53388B1/en not_active IP Right Cessation
- 1982-07-23 IE IE1778/82A patent/IE53387B1/en not_active IP Right Cessation
- 1982-07-26 GR GR68868A patent/GR76429B/el unknown
- 1982-07-26 GR GR68873A patent/GR76430B/el unknown
- 1982-07-27 IL IL66409A patent/IL66409A/xx unknown
- 1982-07-27 IL IL66408A patent/IL66408A/xx unknown
- 1982-07-29 US US06/402,906 patent/US4508720A/en not_active Expired - Fee Related
- 1982-07-29 AU AU86554/82A patent/AU548931B2/en not_active Ceased
- 1982-07-29 AU AU86553/82A patent/AU548930B2/en not_active Ceased
- 1982-07-30 PT PT75350A patent/PT75350B/pt not_active IP Right Cessation
- 1982-07-30 AT AT82401425T patent/ATE12227T1/de not_active IP Right Cessation
- 1982-07-30 ZA ZA825512A patent/ZA825512B/xx unknown
- 1982-07-30 DE DE8282401424T patent/DE3269383D1/de not_active Expired
- 1982-07-30 ZA ZA825513A patent/ZA825513B/xx unknown
- 1982-07-30 EP EP82401424A patent/EP0074863B1/fr not_active Expired
- 1982-07-30 DE DE8282401425T patent/DE3262671D1/de not_active Expired
- 1982-07-30 PT PT75351A patent/PT75351B/pt not_active IP Right Cessation
- 1982-07-30 EP EP82401425A patent/EP0072726B1/fr not_active Expired
- 1982-07-30 AT AT82401424T patent/ATE18216T1/de not_active IP Right Cessation
- 1982-08-02 MA MA19771A patent/MA19560A1/fr unknown
- 1982-08-02 MA MA19773A patent/MA19562A1/fr unknown
- 1982-08-03 CS CS825800A patent/CS229941B2/cs unknown
- 1982-08-03 CS CS825799A patent/CS229940B2/cs unknown
- 1982-08-04 EG EG82474A patent/EG15747A/xx active
- 1982-08-04 EG EG473/82A patent/EG15788A/xx active
- 1982-08-06 YU YU01720/82A patent/YU172082A/xx unknown
- 1982-08-06 PH PH27679A patent/PH18545A/en unknown
- 1982-08-06 CA CA000408843A patent/CA1174240A/en not_active Expired
- 1982-08-06 FI FI822747A patent/FI72968C/fi not_active IP Right Cessation
- 1982-08-06 ES ES514795A patent/ES8305738A1/es not_active Expired
- 1982-08-06 ES ES514794A patent/ES514794A0/es active Granted
- 1982-08-06 NZ NZ201520A patent/NZ201520A/xx unknown
- 1982-08-06 JP JP57137832A patent/JPS5877867A/ja active Granted
- 1982-08-06 SU SU823476698A patent/SU1140685A3/ru active
- 1982-08-06 AR AR290242A patent/AR231441A1/es active
- 1982-08-06 PL PL1982237808A patent/PL137199B1/pl unknown
- 1982-08-06 YU YU01718/82A patent/YU171882A/xx unknown
- 1982-08-06 HU HU822545A patent/HU190028B/hu not_active IP Right Cessation
- 1982-08-06 OA OA57767A patent/OA07175A/xx unknown
- 1982-08-06 JP JP57137833A patent/JPS5877868A/ja active Pending
- 1982-08-06 CA CA000408844A patent/CA1179346A/en not_active Expired
- 1982-08-06 HU HU822542A patent/HU189166B/hu not_active IP Right Cessation
- 1982-08-06 SU SU823475704A patent/SU1138024A3/ru active
- 1982-08-06 AR AR290243A patent/AR231637A1/es active
- 1982-08-06 PL PL1982237809A patent/PL130647B1/pl unknown
- 1982-08-06 OA OA57768A patent/OA07176A/xx unknown
- 1982-08-06 FI FI822748A patent/FI72969C/fi not_active IP Right Cessation
- 1982-08-06 DK DK354382A patent/DK148537C/da not_active IP Right Cessation
- 1982-08-06 NZ NZ201518A patent/NZ201518A/en unknown
- 1982-08-06 DK DK354482A patent/DK148795C/da not_active IP Right Cessation
- 1982-08-07 KR KR8203558A patent/KR880001624B1/ko not_active Expired
- 1982-08-07 KR KR8203557A patent/KR890001569B1/ko not_active Expired
- 1982-08-09 DD DD82242356A patent/DD202715A5/de unknown
- 1982-08-09 DD DD82242359A patent/DD202549A5/de unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5877867A (ja) | ピリダジンのアミノ誘導体、その製造法およびそれを有効成分とする中枢神経系賦活剤 | |
| US3686206A (en) | Pyrazole and pyrazolone aminoketones | |
| US3485847A (en) | 4-aryl-1,4-dihydropyridines | |
| DE2951675C2 (de) | Guanidinothiazolverbindungen, Verfahren zu deren Herstellung und Arzneimittelzubereitungen | |
| US4721711A (en) | Pyridazine derivatives active on the central nervous system, and medicaments in which they are present | |
| CS240998B2 (en) | Production method of 1,4-dihydropiridines | |
| JPS6339866A (ja) | Ｎ‐Ｎ‐二置換‐ω‐［２‐アミノ‐３‐（カルボニルメチル）‐３，４‐ジヒドロキナゾリニル］オキシアルキルアミドおよび関連化合物 | |
| US4772459A (en) | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein | |
| JPS60120872A (ja) | 新規なヘテロ環状化合物及び強心剤 | |
| IE832058L (en) | 1,4-dihydropyridine derivatives | |
| JPS5838262A (ja) | ４−メチル６−フエニルピリダジン誘導体 | |
| US3808224A (en) | 1-(dialkylaminoalkyl)-5-(3-phenyl-5-oxa-2,4-diazolyl)-biguanides | |
| HU191586B (en) | Process for preparing new derivatives of pyridazine and pyrimidine | |
| KR900003301B1 (ko) | 2-피페라지닐-4-페닐 퀴나졸린 유도체 및 그의 산염의 제조 방법 | |
| US4297357A (en) | N-Phenethylacetamide compounds and process for preparation thereof | |
| KR880001077B1 (ko) | 4-페닐 퀴나졸린 유도체의 제조방법 | |
| KR910006128B1 (ko) | N-치환 이미다졸 유도체 | |
| EP0105458B1 (en) | Alpha-aryl-alpha-pyridylalkanoic acid derivatives, process for preparation thereof and pharmaceutical composition comprising the same | |
| PL97347B1 (pl) | Sposob wytwarzania nowych 2-fenylohydrazyno-tiazolin lub-tiazyn | |
| US3511837A (en) | 4-pyrimidyl-1,4-dihydropyridine derivatives and their production | |
| DE69520876T2 (de) | Gamma-diketonverbindung mit thrombozytenaggregationshemmender wirkung | |
| PL103979B1 (pl) | Sposob wytwarzania nowych amin | |
| US3528968A (en) | Heterocyclic substituted imidazoline hydrazones | |
| US3420839A (en) | Aminomethyl pyrazolone derivatives of nicotinamide | |
| US3150139A (en) | Nu-methylpiperazinocyclohexanol derivatives |