ATE12227T1 - Aminopyridazin-derivate mit einer wirkung auf das zentralnervensystem. - Google Patents

Aminopyridazin-derivate mit einer wirkung auf das zentralnervensystem.

Info

Publication number
ATE12227T1
ATE12227T1 AT82401425T AT82401425T ATE12227T1 AT E12227 T1 ATE12227 T1 AT E12227T1 AT 82401425 T AT82401425 T AT 82401425T AT 82401425 T AT82401425 T AT 82401425T AT E12227 T1 ATE12227 T1 AT E12227T1
Authority
AT
Austria
Prior art keywords
effect
nervous system
central nervous
aminopyridazine derivatives
aminopyridazine
Prior art date
Application number
AT82401425T
Other languages
German (de)
English (en)
Inventor
Camille Wermuth
Kathleen Biziere
Jean-Paul Kan
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE12227T1 publication Critical patent/ATE12227T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT82401425T 1981-08-07 1982-07-30 Aminopyridazin-derivate mit einer wirkung auf das zentralnervensystem. ATE12227T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8115380A FR2510998B1 (fr) 1981-08-07 1981-08-07 Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
EP82401425A EP0072726B1 (fr) 1981-08-07 1982-07-30 Composés aminés dérivés de la pyridazine actifs sur le système nerveux central

Publications (1)

Publication Number Publication Date
ATE12227T1 true ATE12227T1 (de) 1985-04-15

Family

ID=9261294

Family Applications (2)

Application Number Title Priority Date Filing Date
AT82401425T ATE12227T1 (de) 1981-08-07 1982-07-30 Aminopyridazin-derivate mit einer wirkung auf das zentralnervensystem.
AT82401424T ATE18216T1 (de) 1981-08-07 1982-07-30 Pyridazin-derivat mit einer wirkung auf das zentralnervensystem.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT82401424T ATE18216T1 (de) 1981-08-07 1982-07-30 Pyridazin-derivat mit einer wirkung auf das zentralnervensystem.

Country Status (30)

Country Link
US (1) US4508720A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0074863B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPS5877867A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (2) KR880001624B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (2) AR231637A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (2) ATE12227T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU548931B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (2) CA1174240A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (2) CS229940B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (2) DD202715A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3262671D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK148537C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (2) EG15747A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES8305738A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (2) FI72968C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2510998B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (2) GR76429B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HU189166B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (2) IE53388B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (2) IL66409A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MA (2) MA19562A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (2) NO157102C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (2) NZ201518A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (2) OA07175A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH18545A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (2) PL130647B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (2) PT75351B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (2) SU1140685A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (2) YU172082A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (2) ZA825513B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) * 1983-01-28 1987-03-03 Kathleen Biziere Process for the preparation of pyridazine derivatives having a psychotropic action
US4628088A (en) * 1984-07-17 1986-12-09 Eli Lilly And Company Preparation of substituted pyridazines
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
US5461053A (en) * 1989-02-07 1995-10-24 Sanofi Pyridazine derivatives
FR2642648B1 (fr) * 1989-02-07 1991-06-21 Sanofi Sa Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2642754B1 (fr) * 1989-02-07 1991-05-24 Sanofi Sa Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
FR2654727B1 (fr) * 1989-11-17 1992-03-27 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
PT93060B (pt) 1989-02-07 1995-12-29 Sanofi Sa Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
US5656631A (en) * 1989-02-07 1997-08-12 Sanofi Pyridazine derivatives
FR2665442B1 (fr) * 1990-07-31 1992-12-04 Sanofi Sa Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
DE60325865D1 (de) * 2002-08-13 2009-03-05 Merck Sharp & Dohme Phenylpyridazin derivative als liganden für gaba-rezeptoren
BRPI0517947A (pt) 2004-11-02 2008-10-21 Univ Northwestern composto de piridazina, composições e métodos
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
EP2015751A2 (en) * 2006-04-28 2009-01-21 Northwestern University Salts of pyridazine compounds
EP2015750A2 (en) * 2006-04-28 2009-01-21 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CN101754762A (zh) * 2006-04-28 2010-06-23 西北大学 用于治疗神经炎症性疾病的包含哒嗪化合物的制剂
RU2555969C1 (ru) * 2014-07-09 2015-07-10 Юлия Алексеевна Щепочкина Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives

Also Published As

Publication number Publication date
ES8305737A1 (es) 1983-04-16
AR231637A1 (es) 1985-01-31
FI822747A0 (fi) 1982-08-06
MA19562A1 (fr) 1983-04-01
OA07175A (fr) 1984-04-30
FR2510998B1 (fr) 1986-01-10
JPH0459312B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1992-09-21
KR840001145A (ko) 1984-03-28
EP0072726B1 (fr) 1985-03-20
JPS5877867A (ja) 1983-05-11
NO157102B (no) 1987-10-12
CA1179346A (en) 1984-12-11
IE821778L (en) 1983-02-07
EP0074863A1 (fr) 1983-03-23
FI822748L (fi) 1983-02-08
ZA825513B (en) 1983-06-29
MA19560A1 (fr) 1983-04-01
ATE18216T1 (de) 1986-03-15
FI72969C (fi) 1987-08-10
PL130647B1 (en) 1984-08-31
IE821779L (en) 1983-02-07
GR76430B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-08-10
SU1140685A3 (ru) 1985-02-15
JPS5877868A (ja) 1983-05-11
PL237808A1 (en) 1983-02-28
HU190028B (en) 1986-08-28
KR890001569B1 (ko) 1989-05-08
CS229941B2 (en) 1984-07-16
EP0074863B1 (fr) 1986-02-26
ES514795A0 (es) 1983-04-16
AU8655482A (en) 1983-02-10
YU172082A (en) 1985-03-20
ES514794A0 (es) 1983-04-16
IE53388B1 (en) 1988-10-26
AR231441A1 (es) 1984-11-30
FR2510998A1 (fr) 1983-02-11
EG15788A (en) 1986-09-30
KR880001624B1 (ko) 1988-09-02
PT75351A (fr) 1982-08-01
NO157861C (no) 1988-06-01
EP0072726A1 (fr) 1983-02-23
EG15747A (en) 1986-06-30
FI72968B (fi) 1987-04-30
FI822748A0 (fi) 1982-08-06
AU8655382A (en) 1983-02-10
US4508720A (en) 1985-04-02
CS229940B2 (en) 1984-07-16
KR840001159A (ko) 1984-03-28
DD202549A5 (de) 1983-09-21
PL237809A1 (en) 1983-02-28
AU548931B2 (en) 1986-01-09
DE3269383D1 (en) 1986-04-03
IL66409A0 (en) 1982-11-30
FI72969B (fi) 1987-04-30
IL66408A (en) 1985-12-31
PT75350A (fr) 1982-08-01
DK148795C (da) 1986-03-10
FI72968C (fi) 1987-08-10
NO822510L (no) 1983-02-08
NO822509L (no) 1983-02-08
NZ201518A (en) 1985-04-30
ES8305738A1 (es) 1983-04-16
NO157861B (no) 1988-02-22
OA07176A (fr) 1984-04-30
NO157102C (no) 1988-01-20
YU171882A (en) 1985-03-20
CA1174240A (en) 1984-09-11
NZ201520A (en) 1985-04-30
IE53387B1 (en) 1988-10-26
SU1138024A3 (ru) 1985-01-30
IL66409A (en) 1985-09-29
DK148537C (da) 1986-01-13
DK354382A (da) 1983-02-08
PT75351B (fr) 1984-08-01
FI822747L (fi) 1983-02-08
DE3262671D1 (en) 1985-04-25
PL137199B1 (en) 1986-05-31
DK148537B (da) 1985-07-29
AU548930B2 (en) 1986-01-09
DD202715A5 (de) 1983-09-28
DK148795B (da) 1985-09-30
GR76429B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-08-10
HU189166B (en) 1986-06-30
PH18545A (en) 1985-08-09
IL66408A0 (en) 1982-11-30
DK354482A (da) 1983-02-08
PT75350B (fr) 1984-08-01
ZA825512B (en) 1983-06-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee