JPH11322745A5 - - Google Patents

Info

Publication number
JPH11322745A5
JPH11322745A5 JP1999109656A JP10965699A JPH11322745A5 JP H11322745 A5 JPH11322745 A5 JP H11322745A5 JP 1999109656 A JP1999109656 A JP 1999109656A JP 10965699 A JP10965699 A JP 10965699A JP H11322745 A5 JPH11322745 A5 JP H11322745A5
Authority
JP
Japan
Prior art keywords
alkyl
phenyl
group
nitrogen
arthritis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1999109656A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11322745A (ja
JP4435325B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JPH11322745A publication Critical patent/JPH11322745A/ja
Publication of JPH11322745A5 publication Critical patent/JPH11322745A5/ja
Application granted granted Critical
Publication of JP4435325B2 publication Critical patent/JP4435325B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP10965699A 1998-04-17 1999-04-16 置換三環式化合物およびそれを含有する組成物 Expired - Fee Related JP4435325B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6216598A 1998-04-17 1998-04-17
US09/062165 1998-04-17

Publications (3)

Publication Number Publication Date
JPH11322745A JPH11322745A (ja) 1999-11-24
JPH11322745A5 true JPH11322745A5 (https=) 2007-04-05
JP4435325B2 JP4435325B2 (ja) 2010-03-17

Family

ID=22040624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10965699A Expired - Fee Related JP4435325B2 (ja) 1998-04-17 1999-04-16 置換三環式化合物およびそれを含有する組成物

Country Status (27)

Country Link
EP (2) EP0950661B1 (https=)
JP (1) JP4435325B2 (https=)
KR (1) KR19990083234A (https=)
CN (1) CN1235968A (https=)
AR (1) AR018185A1 (https=)
AT (2) ATE254128T1 (https=)
AU (1) AU757454B2 (https=)
BR (1) BR9901275A (https=)
CA (1) CA2269256A1 (https=)
CO (1) CO5080728A1 (https=)
CZ (1) CZ137199A3 (https=)
DE (2) DE69912670T2 (https=)
EA (1) EA003129B1 (https=)
ES (2) ES2213668T3 (https=)
HU (1) HUP9901219A1 (https=)
ID (1) ID23219A (https=)
IL (1) IL129484A0 (https=)
NO (1) NO991823L (https=)
NZ (1) NZ335252A (https=)
PE (1) PE20000472A1 (https=)
PL (1) PL332564A1 (https=)
SG (1) SG106035A1 (https=)
SV (1) SV1999000052A (https=)
TR (1) TR199900842A2 (https=)
TW (1) TW555760B (https=)
YU (1) YU19099A (https=)
ZA (1) ZA992773B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2301586A1 (en) * 1997-08-28 1999-03-04 William Louis Macias Method for treatment of non-rheumatoid arthritis
WO2001074817A1 (en) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Hydrazide derivatives
EP1303262A2 (en) * 2000-07-14 2003-04-23 Eli Lilly And Company Use of a spla2 inhibitor for the treatment of sepsis
WO2002050029A2 (en) * 2000-12-18 2002-06-27 Eli Lilly And Company Tetracyclic derivatives as spla2 inhibitors
CA2441077A1 (en) 2001-03-28 2002-10-10 Eli Lilly And Company Substituted carbazoles as inhibitors of spla2
US7160909B2 (en) 2001-08-09 2007-01-09 Eli Lilly And Company Cyclopenta[b]indole derivatives as sPLA2 inhibitors
US7109231B2 (en) 2001-08-09 2006-09-19 Eli Lilly And Company Cyclohept[b]indole derivatives
US6992100B2 (en) 2001-12-06 2006-01-31 Eli Lilly And Company sPLA2 inhibitors
WO2006050007A2 (en) 2004-11-01 2006-05-11 Wyeth Substituted indolizines and derivatives as cns agents
US8716308B2 (en) 2008-01-11 2014-05-06 Albany Molecular Research, Inc. (1-azinone)-substituted pyridoindoles
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
DK2697223T3 (en) * 2011-04-14 2016-09-05 Actelion Pharmaceuticals Ltd 7- (heteroaryl-amino) -6,7,8,9-tetrahydro-pyrido [1,2-a] indole-acetic acid derivatives and their use as prostaglandin D2 receptor
SI2825541T1 (sl) 2012-03-16 2016-10-28 Vitae Pharmaceuticals, Inc. Modulatorji jetrnega receptorja X
ES2607113T3 (es) 2012-03-16 2017-03-29 Vitae Pharmaceuticals, Inc. Moduladores de los receptores X del hígado

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
BR9508298A (pt) * 1994-07-21 1998-11-03 Shionogi & Co Inibidores de indolizina de spla2
EP0779271B1 (en) * 1995-12-13 2001-08-01 Eli Lilly And Company Naphthyl acetamides as sPLA2 inhibitors
CA2269203A1 (en) * 1996-10-30 1998-05-07 Nicholas James Bach Substituted tricyclics
EP1007056A1 (en) * 1997-09-26 2000-06-14 Eli Lilly And Company Method for the treatment of cystic fibrosis
WO1999025340A1 (en) * 1997-11-14 1999-05-27 Eli Lilly And Company Treatment for alzheimer's disease

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