JPH11322713A5 - - Google Patents
Info
- Publication number
- JPH11322713A5 JPH11322713A5 JP1999109629A JP10962999A JPH11322713A5 JP H11322713 A5 JPH11322713 A5 JP H11322713A5 JP 1999109629 A JP1999109629 A JP 1999109629A JP 10962999 A JP10962999 A JP 10962999A JP H11322713 A5 JPH11322713 A5 JP H11322713A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- oxyacetic acid
- carbamoylcarbazol
- compound
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6232898A | 1998-04-17 | 1998-04-17 | |
| US09/062328 | 1998-04-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11322713A JPH11322713A (ja) | 1999-11-24 |
| JPH11322713A5 true JPH11322713A5 (https=) | 2007-04-05 |
Family
ID=22041763
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15240099A Expired - Fee Related JP4435330B2 (ja) | 1998-04-17 | 1999-04-16 | 置換された三環式化合物 |
| JP11109629A Withdrawn JPH11322713A (ja) | 1998-04-17 | 1999-04-16 | 置換三環式化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP15240099A Expired - Fee Related JP4435330B2 (ja) | 1998-04-17 | 1999-04-16 | 置換された三環式化合物 |
Country Status (30)
| Country | Link |
|---|---|
| EP (2) | EP0950657B1 (https=) |
| JP (2) | JP4435330B2 (https=) |
| KR (2) | KR100586761B1 (https=) |
| CN (1) | CN1149193C (https=) |
| AR (2) | AR018186A1 (https=) |
| AT (2) | ATE268756T1 (https=) |
| AU (2) | AU753436B2 (https=) |
| BR (2) | BR9901279A (https=) |
| CA (2) | CA2269246C (https=) |
| CO (2) | CO5031247A1 (https=) |
| CZ (2) | CZ136999A3 (https=) |
| DE (2) | DE69918590T2 (https=) |
| DK (1) | DK0950657T3 (https=) |
| DZ (1) | DZ2769A1 (https=) |
| EA (2) | EA002347B1 (https=) |
| ES (2) | ES2222663T3 (https=) |
| HU (2) | HUP9901220A3 (https=) |
| ID (2) | ID23761A (https=) |
| IL (2) | IL129483A0 (https=) |
| NO (2) | NO314400B1 (https=) |
| NZ (3) | NZ335253A (https=) |
| PE (2) | PE20000432A1 (https=) |
| PL (2) | PL332565A1 (https=) |
| PT (1) | PT950657E (https=) |
| SG (2) | SG81977A1 (https=) |
| SI (1) | SI0950657T1 (https=) |
| TR (2) | TR199900853A2 (https=) |
| TW (1) | TWI238160B (https=) |
| YU (2) | YU19199A (https=) |
| ZA (2) | ZA992772B (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2301586A1 (en) * | 1997-08-28 | 1999-03-04 | William Louis Macias | Method for treatment of non-rheumatoid arthritis |
| DZ2769A1 (fr) * | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
| JP2002542148A (ja) * | 1998-12-21 | 2002-12-10 | イーライ・リリー・アンド・カンパニー | 敗血症の処置のための組み合わせ療法 |
| JP2003505372A (ja) * | 1999-07-19 | 2003-02-12 | イーライ・リリー・アンド・カンパニー | ｓＰＬＡ２インヒビター |
| US6706752B1 (en) | 1999-07-19 | 2004-03-16 | Eli Lilly And Company | sPLA2 inhibitors |
| US6967200B2 (en) | 2000-06-29 | 2005-11-22 | Shionogi & Co., Ltd. | Remedies for cirrhosis |
| WO2002000257A1 (en) * | 2000-06-29 | 2002-01-03 | Shionogi & Co., Ltd. | Remedies for alzheimer's disease |
| DE60130891T2 (de) * | 2000-06-29 | 2008-07-17 | Anthera Pharmaceuticals Inc., San Mateo | Heilmittel für krebs |
| EP1303262A2 (en) * | 2000-07-14 | 2003-04-23 | Eli Lilly And Company | Use of a spla2 inhibitor for the treatment of sepsis |
| EP1345898A2 (en) | 2000-12-18 | 2003-09-24 | Eli Lilly And Company | Teracyclic carbazole derivates and their use as spla2 inhibitors |
| CA2441077A1 (en) | 2001-03-28 | 2002-10-10 | Eli Lilly And Company | Substituted carbazoles as inhibitors of spla2 |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
| DE10249055A1 (de) | 2002-10-22 | 2004-05-06 | Bayer Cropscience Ag | 2-Phenyl-2-substituierte-1,3-diketone |
| JO3598B1 (ar) | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| EP1988098A1 (en) * | 2007-04-27 | 2008-11-05 | AEterna Zentaris GmbH | Novel Tetrahydrocarbazole Derivatives as Ligands of G-protein Coupled Receptors |
| MX2010010471A (es) | 2008-03-26 | 2010-10-20 | Daiichi Sankyo Co Ltd | Derivado de tetrahidroisoquinolina novedoso. |
| TW201000107A (en) | 2008-04-09 | 2010-01-01 | Infinity Pharmaceuticals Inc | Inhibitors of fatty acid amide hydrolase |
| WO2010084402A2 (en) * | 2009-01-22 | 2010-07-29 | Orchid Research Laboratories Ltd. | Heterocyclic compounds as phosphodiesterase inhibitors |
| CA2757622A1 (en) | 2009-04-07 | 2010-10-14 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| WO2010118155A1 (en) | 2009-04-07 | 2010-10-14 | Infinity Pharmaceuticals, Inc. | Inhibitors of fatty acid amide hydrolase |
| MX361692B (es) | 2010-02-03 | 2018-12-13 | Infinity Pharmaceuticals Inc | Inhibidores de amida hidrolasa de ácido graso. |
| AR088377A1 (es) | 2011-10-20 | 2014-05-28 | Siena Biotech Spa | Proceso para la preparacion de 6-cloro-2,3,4,9-tetrahidro-1h-carbazol-1-carboxamida y compuestos intermedios de esta |
| CN102816107B (zh) * | 2012-08-20 | 2015-06-03 | 东南大学 | 咔唑衍生物及其制备方法与用途 |
| CA2889642A1 (en) * | 2012-11-30 | 2014-06-05 | Ge Healthcare Limited | Zinc halide mediated cyclization process leading to tricyclic indoles |
| KR20150088802A (ko) | 2012-11-30 | 2015-08-03 | 지이 헬쓰케어 리미티드 | 트리시클릭 인돌 유도체의 결정화 방법 |
| WO2016116527A1 (de) * | 2015-01-20 | 2016-07-28 | Cynora Gmbh | Organische moleküle, insbesondere zur verwendung in optoelektronischen bauelementen |
| CN108707104A (zh) * | 2018-08-07 | 2018-10-26 | 北京恒信卓元科技有限公司 | 2-氯-1h-咔唑-1,4(9h)-二酮的合成方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3579534A (en) * | 1969-05-09 | 1971-05-18 | American Cyanamid Co | Tetrahydrocarbazolecarboxylates |
| US3939177A (en) * | 1972-11-22 | 1976-02-17 | Sterling Drug Inc. | 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles |
| US3979391A (en) * | 1972-11-22 | 1976-09-07 | Sterling Drug Inc. | 1,2,3,4-Tetrahydrocarbazoles |
| US5420289A (en) * | 1989-10-27 | 1995-05-30 | American Home Products Corporation | Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase |
| PT95692A (pt) * | 1989-10-27 | 1991-09-13 | American Home Prod | Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase |
| US5472978A (en) * | 1991-07-05 | 1995-12-05 | Merck Sharp & Dohme Ltd. | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
| MY110227A (en) * | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| IL109309A (en) * | 1993-04-16 | 2000-06-29 | Lilly Co Eli | 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them |
| IL109311A0 (en) * | 1993-04-16 | 1994-07-31 | Lilly Co Eli | 1H-indole-3-acetamide sPla2 inhibitors |
| EP0749962B1 (en) * | 1995-06-23 | 2000-11-02 | Eli Lilly And Company | 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta(7,6-B)indoles |
| EP0779271B1 (en) * | 1995-12-13 | 2001-08-01 | Eli Lilly And Company | Naphthyl acetamides as sPLA2 inhibitors |
| CA2269203A1 (en) * | 1996-10-30 | 1998-05-07 | Nicholas James Bach | Substituted tricyclics |
| EP1007056A1 (en) * | 1997-09-26 | 2000-06-14 | Eli Lilly And Company | Method for the treatment of cystic fibrosis |
| WO1999025340A1 (en) * | 1997-11-14 | 1999-05-27 | Eli Lilly And Company | Treatment for alzheimer's disease |
| DZ2769A1 (fr) * | 1998-04-17 | 2003-12-01 | Lilly Co Eli | Composés tricycliques substitués. |
-
1999
- 1999-04-14 DZ DZ990069A patent/DZ2769A1/xx active
- 1999-04-15 ID IDP990341D patent/ID23761A/id unknown
- 1999-04-15 IL IL12948399A patent/IL129483A0/xx unknown
- 1999-04-15 ID IDP990340D patent/ID23287A/id unknown
- 1999-04-15 IL IL12948599A patent/IL129485A0/xx unknown
- 1999-04-16 CN CNB991079574A patent/CN1149193C/zh not_active Expired - Fee Related
- 1999-04-16 ZA ZA9902772A patent/ZA992772B/xx unknown
- 1999-04-16 EA EA199900301A patent/EA002347B1/ru not_active IP Right Cessation
- 1999-04-16 BR BR9901279-0A patent/BR9901279A/pt not_active IP Right Cessation
- 1999-04-16 HU HU9901220A patent/HUP9901220A3/hu unknown
- 1999-04-16 BR BR9902365-2A patent/BR9902365A/pt not_active IP Right Cessation
- 1999-04-16 EP EP99302967A patent/EP0950657B1/en not_active Expired - Lifetime
- 1999-04-16 NO NO19991821A patent/NO314400B1/no not_active IP Right Cessation
- 1999-04-16 SG SG9901869A patent/SG81977A1/en unknown
- 1999-04-16 TR TR1999/00853A patent/TR199900853A2/xx unknown
- 1999-04-16 EP EP99302941A patent/EP0952149B1/en not_active Expired - Lifetime
- 1999-04-16 PL PL99332565A patent/PL332565A1/xx not_active Application Discontinuation
- 1999-04-16 ES ES99302941T patent/ES2222663T3/es not_active Expired - Lifetime
- 1999-04-16 ZA ZA9902771A patent/ZA992771B/xx unknown
- 1999-04-16 NO NO19991822A patent/NO312240B1/no not_active IP Right Cessation
- 1999-04-16 CO CO99022884A patent/CO5031247A1/es unknown
- 1999-04-16 AU AU23817/99A patent/AU753436B2/en not_active Ceased
- 1999-04-16 YU YU19199A patent/YU19199A/sh unknown
- 1999-04-16 KR KR1019990013438A patent/KR100586761B1/ko not_active Expired - Fee Related
- 1999-04-16 CA CA002269246A patent/CA2269246C/en not_active Expired - Fee Related
- 1999-04-16 CZ CZ991369A patent/CZ136999A3/cs unknown
- 1999-04-16 NZ NZ335253A patent/NZ335253A/xx unknown
- 1999-04-16 AT AT99302941T patent/ATE268756T1/de not_active IP Right Cessation
- 1999-04-16 EA EA199900303A patent/EA002816B1/ru not_active IP Right Cessation
- 1999-04-16 SI SI9930650T patent/SI0950657T1/xx unknown
- 1999-04-16 DE DE69918590T patent/DE69918590T2/de not_active Expired - Lifetime
- 1999-04-16 CA CA002269262A patent/CA2269262A1/en not_active Abandoned
- 1999-04-16 KR KR1019990013436A patent/KR19990083232A/ko not_active Withdrawn
- 1999-04-16 HU HU9901221A patent/HUP9901221A3/hu unknown
- 1999-04-16 PE PE1999000314A patent/PE20000432A1/es not_active Application Discontinuation
- 1999-04-16 PT PT99302967T patent/PT950657E/pt unknown
- 1999-04-16 TW TW088106130A patent/TWI238160B/zh not_active IP Right Cessation
- 1999-04-16 AT AT99302967T patent/ATE271037T1/de active
- 1999-04-16 DK DK99302967T patent/DK0950657T3/da active
- 1999-04-16 DE DE69917833T patent/DE69917833T2/de not_active Expired - Lifetime
- 1999-04-16 YU YU18999A patent/YU18999A/sh unknown
- 1999-04-16 CZ CZ991370A patent/CZ137099A3/cs unknown
- 1999-04-16 AU AU23819/99A patent/AU753547B2/en not_active Ceased
- 1999-04-16 NZ NZ507564A patent/NZ507564A/xx unknown
- 1999-04-16 ES ES99302967T patent/ES2226286T3/es not_active Expired - Lifetime
- 1999-04-16 NZ NZ335251A patent/NZ335251A/xx unknown
- 1999-04-16 AR ARP990101770A patent/AR018186A1/es not_active Application Discontinuation
- 1999-04-16 TR TR1999/00843A patent/TR199900843A2/xx unknown
- 1999-04-16 PL PL99332566A patent/PL332566A1/xx not_active Application Discontinuation
- 1999-04-16 CO CO99022897A patent/CO5011054A1/es unknown
- 1999-04-16 PE PE1999000320A patent/PE20000476A1/es not_active Application Discontinuation
- 1999-04-16 JP JP15240099A patent/JP4435330B2/ja not_active Expired - Fee Related
- 1999-04-16 SG SG9901681A patent/SG81976A1/en unknown
- 1999-04-16 AR ARP990101771A patent/AR018593A1/es active IP Right Grant
- 1999-04-16 JP JP11109629A patent/JPH11322713A/ja not_active Withdrawn
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