ID23287A - Trisiklik tersubstitusi - Google Patents

Trisiklik tersubstitusi

Info

Publication number
ID23287A
ID23287A IDP990340D ID990340D ID23287A ID 23287 A ID23287 A ID 23287A ID P990340 D IDP990340 D ID P990340D ID 990340 D ID990340 D ID 990340D ID 23287 A ID23287 A ID 23287A
Authority
ID
Indonesia
Prior art keywords
trisiclic
substituted
substituted trisiclic
Prior art date
Application number
IDP990340D
Other languages
English (en)
Inventor
Benjamin Alan Anderson
Nicholas James Batch
Jolie Anne Bastian
Richard Waltz Harper
Gary Alan Hite
Michael Dean Kinnick
Ho-Shen Nmn Lin
Richard James Loncharich
John Mcneill Mcgill Iii
Edward David Mihelich
John Michael Morin
Michael Leroy Phillips
Michael Enrico Richett
Daniel Jon Sall
Jason Scott Sawyer
Richard Walter Schevitz
Robert Theodore Vasileff
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID23287A publication Critical patent/ID23287A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
IDP990340D 1998-04-17 1999-04-15 Trisiklik tersubstitusi ID23287A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6232898A 1998-04-17 1998-04-17

Publications (1)

Publication Number Publication Date
ID23287A true ID23287A (id) 2000-04-05

Family

ID=22041763

Family Applications (2)

Application Number Title Priority Date Filing Date
IDP990340D ID23287A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi
IDP990341D ID23761A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Family Applications After (1)

Application Number Title Priority Date Filing Date
IDP990341D ID23761A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Country Status (30)

Country Link
EP (2) EP0952149B1 (id)
JP (2) JP4435330B2 (id)
KR (2) KR19990083232A (id)
CN (1) CN1149193C (id)
AR (2) AR018593A1 (id)
AT (2) ATE268756T1 (id)
AU (2) AU753436B2 (id)
BR (2) BR9901279A (id)
CA (2) CA2269262A1 (id)
CO (2) CO5011054A1 (id)
CZ (2) CZ137099A3 (id)
DE (2) DE69917833T2 (id)
DK (1) DK0950657T3 (id)
DZ (1) DZ2769A1 (id)
EA (2) EA002347B1 (id)
ES (2) ES2222663T3 (id)
HU (2) HUP9901220A3 (id)
ID (2) ID23287A (id)
IL (2) IL129485A0 (id)
NO (2) NO314400B1 (id)
NZ (3) NZ335251A (id)
PE (2) PE20000432A1 (id)
PL (2) PL332565A1 (id)
PT (1) PT950657E (id)
SG (2) SG81977A1 (id)
SI (1) SI0950657T1 (id)
TR (2) TR199900853A3 (id)
TW (1) TWI238160B (id)
YU (2) YU19199A (id)
ZA (2) ZA992772B (id)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1011670A4 (en) * 1997-08-28 2004-10-27 Lilly Co Eli PROCESS FOR TREATING NON-RHUMATOID POLYARTHRITIS
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
WO2000037022A2 (en) * 1998-12-21 2000-06-29 Eli Lilly And Company Combination therapy for the treatment of sepsis
JP2003505372A (ja) * 1999-07-19 2003-02-12 イーライ・リリー・アンド・カンパニー ｓＰＬＡ２インヒビター
US6706752B1 (en) 1999-07-19 2004-03-16 Eli Lilly And Company sPLA2 inhibitors
TW583000B (en) * 2000-06-29 2004-04-11 Shionogi & Co X-type sPLA2 inhibitor as a cancer therapeutical agent
AU2001267825A1 (en) 2000-06-29 2002-01-08 Shionogi And Co., Ltd. Remedies for cirrhosis
US20040102442A1 (en) * 2000-06-29 2004-05-27 Kohji Hanasaki Remedies for alzheimer's disease
CA2413582A1 (en) * 2000-07-14 2002-01-24 Eli Lilly And Company Use of a spla2 inhibitor for the treatment of sepsis
EP1345898A2 (en) 2000-12-18 2003-09-24 Eli Lilly And Company Teracyclic carbazole derivates and their use as spla2 inhibitors
WO2002079154A1 (en) * 2001-03-28 2002-10-10 Eli Lilly And Company Substituted carbazoles as inhibitors of spla2
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
DE10249055A1 (de) 2002-10-22 2004-05-06 Bayer Cropscience Ag 2-Phenyl-2-substituierte-1,3-diketone
JO3598B1 (ar) 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
EP1988098A1 (en) * 2007-04-27 2008-11-05 AEterna Zentaris GmbH Novel Tetrahydrocarbazole Derivatives as Ligands of G-protein Coupled Receptors
MX2010010471A (es) 2008-03-26 2010-10-20 Daiichi Sankyo Co Ltd Derivado de tetrahidroisoquinolina novedoso.
CA2721060A1 (en) 2008-04-09 2009-10-15 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
WO2010084402A2 (en) * 2009-01-22 2010-07-29 Orchid Research Laboratories Ltd. Heterocyclic compounds as phosphodiesterase inhibitors
JP2012523425A (ja) 2009-04-07 2012-10-04 インフイニトイ プハルマセウトイカルス インコーポレイテッド 脂肪酸アミドヒドロラーゼの阻害薬
EP2416660B1 (en) 2009-04-07 2014-07-02 Infinity Pharmaceuticals, Inc. Inhibitors of fatty acid amide hydrolase
MX361011B (es) 2010-02-03 2018-11-26 Infinity Pharmaceuticals Inc Inhibidores de amida hidrolasa de ácido graso.
AR088377A1 (es) 2011-10-20 2014-05-28 Siena Biotech Spa Proceso para la preparacion de 6-cloro-2,3,4,9-tetrahidro-1h-carbazol-1-carboxamida y compuestos intermedios de esta
CN102816107B (zh) * 2012-08-20 2015-06-03 东南大学 咔唑衍生物及其制备方法与用途
EP2925723A1 (en) * 2012-11-30 2015-10-07 GE Healthcare Limited Zinc halide mediated cyclization process leading to tricyclic indoles
IN2015DN03978A (id) 2012-11-30 2015-10-02 Ge Healthcare Ltd
EP3248230B1 (de) * 2015-01-20 2020-05-06 cynora GmbH Verwendung organischer moleküle in optoelektronischen bauelementen
CN108707104A (zh) * 2018-08-07 2018-10-26 北京恒信卓元科技有限公司 2-氯-1h-咔唑-1,4(9h)-二酮的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579534A (en) * 1969-05-09 1971-05-18 American Cyanamid Co Tetrahydrocarbazolecarboxylates
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
US3939177A (en) * 1972-11-22 1976-02-17 Sterling Drug Inc. 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
EP0593559A1 (en) * 1991-07-05 1994-04-27 MERCK SHARP & DOHME LTD. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
CA2179678A1 (en) * 1995-06-23 1996-12-24 Michael Edward Flaugh 6-substituted-1,2,3,4-tetrahydro-9h-carbazoles and 7-substituted-10h-cyclohepta¬7,6-b| indoles
KR19990072110A (ko) * 1995-12-13 1999-09-27 피터 지. 스트링거 Spla2 억제제인 나프틸 아세트아미드
CZ136899A3 (cs) * 1996-10-30 1999-09-15 Eli Lilly And Company Substituované tricyklické sloučeniny
WO1999016453A1 (en) * 1997-09-26 1999-04-08 Eli Lilly And Company Method for the treatment of cystic fibrosis
CA2310250A1 (en) * 1997-11-14 1999-05-27 August Masaru Watanabe Treatment for alzheimer's disease
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.

Also Published As

Publication number Publication date
DE69918590T2 (de) 2005-07-21
EA002816B1 (ru) 2002-10-31
ZA992771B (en) 2002-04-18
NO991822L (no) 1999-10-18
HU9901221D0 (en) 1999-06-28
DK0950657T3 (da) 2004-11-22
EP0952149A2 (en) 1999-10-27
NZ335253A (en) 2000-11-24
AU753547B2 (en) 2002-10-24
ATE268756T1 (de) 2004-06-15
JPH11322713A (ja) 1999-11-24
KR19990083233A (ko) 1999-11-25
DZ2769A1 (fr) 2003-12-01
BR9902365A (pt) 2001-04-24
ID23761A (id) 2000-05-11
CZ136999A3 (cs) 1999-11-17
CO5031247A1 (es) 2001-04-27
PE20000432A1 (es) 2000-05-23
EP0950657A2 (en) 1999-10-20
SG81976A1 (en) 2001-07-24
NO991822D0 (no) 1999-04-16
CN1253948A (zh) 2000-05-24
PL332565A1 (en) 1999-10-25
IL129483A0 (en) 2000-02-29
BR9901279A (pt) 2000-05-02
EA199900301A3 (ru) 2000-04-24
EP0952149A3 (en) 2001-08-16
TWI238160B (en) 2005-08-21
EA199900303A3 (ru) 2000-04-24
TR199900843A2 (xx) 2000-02-21
DE69918590D1 (de) 2004-08-19
CA2269246C (en) 2009-08-25
DE69917833T2 (de) 2005-07-14
AR018593A1 (es) 2001-11-28
EP0950657B1 (en) 2004-07-14
NO991821L (no) 1999-10-18
NO314400B1 (no) 2003-03-17
CO5011054A1 (es) 2001-02-28
YU19199A (sh) 2002-08-12
PE20000476A1 (es) 2000-06-02
AU2381799A (en) 1999-10-28
ZA992772B (en) 2002-07-16
CN1149193C (zh) 2004-05-12
TR199900853A2 (xx) 1999-11-22
ATE271037T1 (de) 2004-07-15
HU9901220D0 (en) 1999-06-28
EA199900303A2 (ru) 1999-10-28
SG81977A1 (en) 2001-07-24
HU9901221A (hu) 2000-04-28
HUP9901220A3 (en) 2001-11-28
YU18999A (sh) 2002-08-12
AR018186A1 (es) 2001-10-31
NO991821D0 (no) 1999-04-16
NZ335251A (en) 2000-11-24
JP4435330B2 (ja) 2010-03-17
HUP9901221A3 (en) 2001-11-28
NO312240B1 (no) 2002-04-15
JP2000026416A (ja) 2000-01-25
HU9901220A (hu) 2000-04-28
AU753436B2 (en) 2002-10-17
ES2222663T3 (es) 2005-02-01
NZ507564A (en) 2002-10-25
ES2226286T3 (es) 2005-03-16
AU2381999A (en) 1999-10-28
SI0950657T1 (en) 2005-02-28
EP0950657A3 (en) 2001-08-16
CA2269262A1 (en) 1999-10-17
PT950657E (pt) 2004-11-30
CA2269246A1 (en) 1999-10-17
EA002347B1 (ru) 2002-04-25
KR100586761B1 (ko) 2006-06-08
KR19990083232A (ko) 1999-11-25
EA199900301A2 (ru) 1999-10-28
CZ137099A3 (cs) 1999-11-17
DE69917833D1 (de) 2004-07-15
IL129485A0 (en) 2000-02-29
EP0952149B1 (en) 2004-06-09
PL332566A1 (en) 1999-10-25
TR199900853A3 (tr) 1999-11-22

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