GR1001124B
(el)
*
|
1989-11-20 |
1993-04-28 |
Pfizer |
Θεραπευτικοι παραγοντες κουινουκλιδινης.
|
US5332817A
(en)
*
|
1990-01-04 |
1994-07-26 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles
|
WO1991009844A1
(fr)
*
|
1990-01-04 |
1991-07-11 |
Pfizer Inc. |
Antagonistes de la substance p
|
US5232929A
(en)
*
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
US5364943A
(en)
*
|
1991-11-27 |
1994-11-15 |
Pfizer Inc. |
Preparation of substituted piperidines
|
DK0532527T3
(da)
*
|
1990-06-01 |
1995-01-02 |
Pfizer |
3-amino-2-arylquinuclidiner, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse
|
CA2086434C
(fr)
*
|
1990-07-23 |
1998-09-22 |
John A. Lowe, Iii |
Derives quinuclidine
|
CA2089736A1
(fr)
*
|
1990-09-28 |
1992-03-29 |
Manoj C. Desai |
Analogues a noyaux condenses d'heterocycles azotes non aromatiques
|
US5138060A
(en)
*
|
1991-01-03 |
1992-08-11 |
Pfizer Inc. |
Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
|
US5216163A
(en)
*
|
1991-01-03 |
1993-06-01 |
Pfizer Inc |
Process for preparing azabicyclo[2.2.2]octan-3-imines
|
CA2100163A1
(fr)
*
|
1991-01-10 |
1992-07-11 |
John A. Lowe, Iii |
Sels de n-alkylquinuclidinium
|
EP0499313B1
(fr)
*
|
1991-02-11 |
1997-06-11 |
MERCK SHARP & DOHME LTD. |
Composés azabicycliques, compositions pharmaceutiques les contenant et leur utilisation thérapeutique
|
WO1992015585A1
(fr)
*
|
1991-03-01 |
1992-09-17 |
Pfizer Inc. |
Derives de 1-azabicyclo-[3.2.2]-nonan-3-amine
|
RU2105001C1
(ru)
*
|
1991-03-26 |
1998-02-20 |
Пфайзер Инк. |
Способ получения замещенных 3-аминопиперидинов
|
FR2676442B1
(fr)
*
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
ATE211743T1
(de)
*
|
1991-05-22 |
2002-01-15 |
Pfizer |
Substituierte 3-aminochinuclidine
|
US5716965A
(en)
*
|
1991-05-22 |
1998-02-10 |
Pfizer Inc. |
Substituted 3-aminoquinuclidines
|
WO1992020661A1
(fr)
*
|
1991-05-22 |
1992-11-26 |
Merck & Co., Inc. |
N, n-diacylpiperazines
|
DE9290063U1
(de)
*
|
1991-05-31 |
1994-02-24 |
Pfizer |
Chinuclidin-Derivate
|
CA2109613C
(fr)
*
|
1991-06-20 |
1996-11-19 |
John Adams Lowe Iii |
Derives fluoroalcoxybenzylamines d'heterocycles azotes
|
TW202432B
(fr)
*
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
US5288730A
(en)
*
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
EP0536817A1
(fr)
*
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Composés azabicycliques comme antagonistes des tachykinines
|
MY110227A
(en)
*
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
WO1993004040A1
(fr)
*
|
1991-08-20 |
1993-03-04 |
Merck Sharp & Dohme Limited |
Composes azacycliques, procedes de preparation et compositions pharmaceutiques les contenant
|
EP0533280B2
(fr)
*
|
1991-09-20 |
2004-12-01 |
Glaxo Group Limited |
Nouvelle indication médicale pour les antagonistes des tachykinines
|
DE69232588T2
(de)
*
|
1991-09-26 |
2002-08-22 |
Pfizer |
Kondensierte trizyklische, stickstoffenthaltende Verbindungen als Substanz P Rezeptor Antagonisten
|
WO1993009116A1
(fr)
*
|
1991-11-07 |
1993-05-13 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Compose a base de quinuclidine et utilisation dudit compose en medecine
|
ATE161821T1
(de)
*
|
1991-11-12 |
1998-01-15 |
Pfizer |
Azyklische ethylendiaminderivate als 'substance p rezeptor' antagonisten
|
FR2688219B1
(fr)
|
1992-03-03 |
1994-07-08 |
Sanofi Elf |
Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
|
JP2656702B2
(ja)
*
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
WO1993021181A1
(fr)
*
|
1992-04-15 |
1993-10-28 |
Merck Sharp & Dohme Limited |
Composes azacycliques
|
US5444074A
(en)
*
|
1992-04-15 |
1995-08-22 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
ES2164657T3
(es)
*
|
1992-05-18 |
2002-03-01 |
Pfizer |
Derivados aza-biciclicos puenteados como antagonistas de la sustancia p.
|
US6048859A
(en)
|
1992-06-29 |
2000-04-11 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
US5719147A
(en)
*
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
US5637699A
(en)
*
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
JP2683783B2
(ja)
*
|
1992-07-10 |
1997-12-03 |
雪印乳業株式会社 |
シェーグレン症候群治療剤
|
GB9216911D0
(en)
*
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
ATE208376T1
(de)
*
|
1992-08-19 |
2001-11-15 |
Pfizer |
Substituierte benzylamin-stickstoff enthaltende nichtaromatische heterocyclen
|
US5387595A
(en)
*
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
FR2695641B1
(fr)
*
|
1992-09-11 |
1994-11-25 |
Rhone Poulenc Rorer Sa |
(Amino-3 phényl)-1 éthanesulfonate d'hydroquinine optiquement actif, sa préparation et son utilisation.
|
US5604241A
(en)
*
|
1992-10-21 |
1997-02-18 |
Pfizer Inc. |
Substituted benzylaminoquinuclidines as substance P antagonists
|
JP2656699B2
(ja)
*
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
JP2656700B2
(ja)
*
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
US5837711A
(en)
*
|
1992-10-28 |
1998-11-17 |
Pfizer Inc. |
Substituted quinuclidines as substance P antagonists
|
NZ254604A
(en)
*
|
1992-11-12 |
1997-06-24 |
Pfizer |
Quinuclidine derivative and pharmaceutical compositions thereof
|
US5344830A
(en)
*
|
1992-12-10 |
1994-09-06 |
Merck & Co., Inc. |
N,N-diacylpiperazine tachykinin antagonists
|
PT675886E
(pt)
*
|
1992-12-10 |
2000-12-29 |
Pfizer |
Heterociclos nao aromaticos com substituintes aminometileno e sua utilizacao como antagonistas da substancia p
|
US5830854A
(en)
*
|
1992-12-14 |
1998-11-03 |
Merck Sharp & Dohme, Limited |
Method of treating cystic fibrosis using a tachykinin receptor antagonist
|
JP2832754B2
(ja)
*
|
1993-03-04 |
1998-12-09 |
ファイザー・インク. |
サブスタンスpアンタゴニストとしてのスピロアザ環式誘導体
|
US5496833A
(en)
*
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
IL109646A0
(en)
*
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
JP2822274B2
(ja)
*
|
1993-05-19 |
1998-11-11 |
ファイザー製薬株式会社 |
P物質拮抗剤としてのヘテロ原子置換アルキルベンジルアミノキヌクリジン類
|
US5393762A
(en)
*
|
1993-06-04 |
1995-02-28 |
Pfizer Inc. |
Pharmaceutical agents for treatment of emesis
|
US5348955A
(en)
*
|
1993-06-22 |
1994-09-20 |
Merck & Co., Inc. |
N,N-diacylpiperazines
|
DK0708771T3
(da)
*
|
1993-07-15 |
1999-06-21 |
Pfizer |
Benzyloxyquinuclidiner som substans P antagonister
|
US5854262A
(en)
*
|
1993-10-07 |
1998-12-29 |
Pfizer Inc. |
Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists
|
PE45195A1
(es)
*
|
1994-03-03 |
1996-01-17 |
Boehringer Ingelheim Kg |
Derivado de aminoacido, procedimiento para su preparacion y composicion farmaceutica que lo contiene
|
US5922878A
(en)
*
|
1994-03-03 |
1999-07-13 |
Boehringer Ingelheim Gmbh |
Amino acid derivatives, processes for preparing them and pharmaceutical compositions containing these compounds
|
TW385308B
(en)
*
|
1994-03-04 |
2000-03-21 |
Merck & Co Inc |
Prodrugs of morpholine tachykinin receptor antagonists
|
FR2719474B1
(fr)
|
1994-05-05 |
1996-05-31 |
Oreal |
Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue.
|
US6203803B1
(en)
|
1994-12-14 |
2001-03-20 |
Societe L'oreal S.A. |
Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained
|
FR2719476B1
(fr)
*
|
1994-05-05 |
1997-05-23 |
Oreal |
Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue.
|
TW397825B
(en)
*
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
FR2725900B1
(fr)
*
|
1994-10-21 |
1997-07-18 |
Sanofi Sa |
Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
|
IL116249A
(en)
*
|
1994-12-12 |
2003-07-06 |
Pfizer |
Nk-1 receptor antagonists for the treatment of neuronal damage and stroke
|
FR2728166A1
(fr)
|
1994-12-19 |
1996-06-21 |
Oreal |
Composition topique contenant un antagoniste de substance p
|
FR2728169A1
(fr)
|
1994-12-19 |
1996-06-21 |
Oreal |
Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
|
FR2728165A1
(fr)
|
1994-12-19 |
1996-06-21 |
Oreal |
Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
|
FR2729954B1
(fr)
|
1995-01-30 |
1997-08-01 |
Sanofi Sa |
Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
|
WO1997003066A1
(fr)
*
|
1995-07-07 |
1997-01-30 |
Pfizer Pharmaceuticals Inc. |
Composes de benzolactam substitues utilises comme antagonistes de la substance p
|
US6288225B1
(en)
|
1996-05-09 |
2001-09-11 |
Pfizer Inc |
Substituted benzolactam compounds as substance P antagonists
|
PE8798A1
(es)
*
|
1995-07-17 |
1998-03-02 |
Pfizer |
Procedimiento de separacion de los enantiomeros del 1-azabiciclo[2.2.2] octan-3-amina, 2-(difenilmetil) -n- [[2-metoxi-5-(1-metiletil) fenil] metil]
|
TW458774B
(en)
|
1995-10-20 |
2001-10-11 |
Pfizer |
Antiemetic pharmaceutical compositions
|
FR2741262B1
(fr)
|
1995-11-20 |
1999-03-05 |
Oreal |
Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
|
MX9706944A
(es)
*
|
1996-09-12 |
1998-08-30 |
Pfizer |
Quinuclidinas sustituidas con tetrazolilo como antagonistas de la sustancia p.
|
US6117855A
(en)
|
1996-10-07 |
2000-09-12 |
Merck Sharp & Dohme Ltd. |
Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent
|
US6100256A
(en)
*
|
1996-12-02 |
2000-08-08 |
Merck Sharp & Dohme Ltd. |
Use of NK-1 receptors antagonists for treating schizophrenic disorders
|
US6613765B1
(en)
|
1996-12-02 |
2003-09-02 |
Merck Sharp & Dohme Limited |
Use of NK-1 receptor antagonists for treating major depressive disorders
|
ATE282416T1
(de)
*
|
1996-12-02 |
2004-12-15 |
Merck Sharp & Dohme |
Die verwendung von nk-1 rezeptor antagonisten für die behandlung von substanz-verwendung störungen
|
JP2001508412A
(ja)
*
|
1996-12-02 |
2001-06-26 |
メルク シヤープ エンド ドーム リミテツド |
認識障害の治療のためのnk−1受容体拮抗薬の使用
|
US6114315A
(en)
*
|
1996-12-02 |
2000-09-05 |
Merck Sharp & Dohme Ltd. |
Use of NK-1 receptor antagonists for treating major depressive disorders with anxiety
|
CA2273809A1
(fr)
*
|
1996-12-02 |
1998-06-11 |
Merck Sharp & Dohme Limited |
Utilisation d'antagonistes du recepteur nk-1 dans le traitement des diskynesies
|
US5977104A
(en)
*
|
1996-12-02 |
1999-11-02 |
Merck Sharp & Dohme Ltd. |
Use of NK-1 receptor antagonists for treating bipolar disorders
|
EP0942730A1
(fr)
*
|
1996-12-02 |
1999-09-22 |
MERCK SHARP & DOHME LTD. |
Utilisation d'antagonistes du recepteur nk-1 dans le traitement des troubles bipolaires
|
AU731349B2
(en)
*
|
1996-12-02 |
2001-03-29 |
Merck Sharp & Dohme Limited |
Use of NK-1 receptor antagonists for treating sexual dysfunctions
|
GB9716463D0
(en)
*
|
1997-08-04 |
1997-10-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
US6271230B1
(en)
|
1997-12-01 |
2001-08-07 |
Merck Sharp & Dohme Limited |
Use of NK-1 receptor antagonists for treating cognitive disorders
|
US6156749A
(en)
*
|
1997-12-01 |
2000-12-05 |
Merck Sharp & Dohme Limited |
Use of NK-1 receptor antagonists for treating movement disorders
|
US6087348A
(en)
*
|
1997-12-01 |
2000-07-11 |
Merck Sharp & Dohme Ltd. |
Use of NK-1 receptor antagonists for treating stress disorders
|
WO2000010545A2
(fr)
*
|
1998-08-25 |
2000-03-02 |
Novartis Ag |
Utilisations pharmaceutiques
|
US6387925B1
(en)
*
|
1999-06-01 |
2002-05-14 |
Pfizer Inc. |
Polymorphs of a crystalline azo-bicyclo (2.2.2) oct-3-yl amine citrate and their pharmaceutical compositions
|
US6262067B1
(en)
*
|
1999-06-22 |
2001-07-17 |
Pfizer Inc. |
Polymorphs of a crystalline azo-bicyclo 2,2,2 OCT-3-yl amine dihydrochloride and their pharmaceutical compositions
|
JP2001172178A
(ja)
*
|
1999-10-25 |
2001-06-26 |
Pfizer Prod Inc |
偏頭痛治療用のnk−1レセプターアンタゴニスト及びエレトリプタン
|
CN1414953A
(zh)
|
1999-11-03 |
2003-04-30 |
阿尔巴尼分子研究公司 |
芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和5-羟色胺重摄取的用途
|
US7163949B1
(en)
|
1999-11-03 |
2007-01-16 |
Amr Technology, Inc. |
4-phenyl substituted tetrahydroisoquinolines and use thereof
|
USRE44578E1
(en)
|
2000-04-10 |
2013-11-05 |
Teva Pharmaceutical Industries, Ltd. |
Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
|
IL142810A0
(en)
*
|
2000-05-03 |
2002-03-10 |
Pfizer Prod Inc |
Pharmaceutical uses for fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
|
AU7334901A
(en)
|
2000-07-11 |
2002-01-21 |
Du Pont Pharm Co |
Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
|
US20020049211A1
(en)
*
|
2000-09-06 |
2002-04-25 |
Sobolov-Jaynes Susan Beth |
Combination treatment for depression and anxiety
|
EP1192952A3
(fr)
*
|
2000-09-28 |
2003-03-26 |
Pfizer Products Inc. |
Composition pour le traitement de la dépression et de l'anxieté contenant un antagoniste du recepteur NK-3 et un antagoniste du récepteur NK-1
|
HUP0401154A2
(hu)
*
|
2001-07-20 |
2004-10-28 |
Pfizer Products Inc. |
NK-1 receptor antagonisták használata kutyák, macskák és lovak nemkívánatos viselkedésének módosítására
|
US6861526B2
(en)
*
|
2002-10-16 |
2005-03-01 |
Pfizer Inc. |
Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
|
CA2514656A1
(fr)
*
|
2003-01-31 |
2004-08-12 |
Pfizer Products Inc. |
Antagonistes 5ht7 et agonistes inverses
|
US20050136487A1
(en)
*
|
2003-10-27 |
2005-06-23 |
Meyer Donald W. |
Transmissible spongiform encephalopathy detection in cervids, sheep and goats
|
WO2005051919A1
(fr)
*
|
2003-11-26 |
2005-06-09 |
Pfizer Products Inc. |
Derives d'aminopyrazole en tant qu'inhibiteurs de la gsk-3
|
MX2007000428A
(es)
|
2004-07-15 |
2008-03-05 |
Amr Technology Inc |
Tetrahidroisoquinolinas sustituidas con arilo y heteroarilo y uso de las mismas para bloquear la captacion de norepinefrina, dopamina y serotonina.
|
ATE550019T1
(de)
|
2005-05-17 |
2012-04-15 |
Merck Sharp & Dohme |
Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
|
CA2615403C
(fr)
|
2005-07-15 |
2015-06-16 |
Amr Technology, Inc. |
Tetrahydrobenzazepines substituees par aryle et heteroaryle, et leur utilisation pour bloquer la reabsorption de la noradrenaline, de la dopamine, et de la serotonine
|
AU2006297443B2
(en)
|
2005-09-29 |
2010-08-12 |
Merck Sharp & Dohme Corp. |
Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
CA2664113C
(fr)
|
2006-09-22 |
2013-05-28 |
Merck & Co., Inc. |
Utilisation de la platencine et de la platensimycine en tant qu'inhibiteurs de la synthese des acides gras pour traiter l'obesite, lediabete et le cancer
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
EP2109608B1
(fr)
|
2007-01-10 |
2011-03-23 |
Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. |
Indazoles à substitution amide utilisés comme inhibiteurs de la poly(adp-ribose)polymérase (parp)
|
CN101641099A
(zh)
|
2007-01-24 |
2010-02-03 |
葛兰素集团有限公司 |
包含3,5-二氨基-6-(2,3-二氯苯基)-1,2,4-三嗪或r(-)-2,4-二氨基-5-(2,3-二氯苯基)-6-氟甲基嘧啶和nk1的药物组合物
|
US8106086B2
(en)
|
2007-04-02 |
2012-01-31 |
Msd K.K. |
Indoledione derivative
|
JP5501227B2
(ja)
|
2007-06-27 |
2014-05-21 |
メルク・シャープ・アンド・ドーム・コーポレーション |
ヒストンデアセチラーゼ阻害剤としての4−カルボキシベンジルアミノ誘導体
|
AU2009222122A1
(en)
|
2008-03-03 |
2009-09-11 |
Tiger Pharmatech |
Tyrosine kinase inhibitors
|
US9156812B2
(en)
|
2008-06-04 |
2015-10-13 |
Bristol-Myers Squibb Company |
Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
|
AR071997A1
(es)
|
2008-06-04 |
2010-07-28 |
Bristol Myers Squibb Co |
Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
|
UA105182C2
(ru)
|
2008-07-03 |
2014-04-25 |
Ньюрексон, Інк. |
Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
|
EP2350010B1
(fr)
|
2008-10-30 |
2014-03-26 |
Merck Sharp & Dohme Corp. |
Antagonistes d'isonicotinamide des récepteurs de l'orexine
|
TW201031664A
(en)
*
|
2009-01-26 |
2010-09-01 |
Targacept Inc |
Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
|
EP2413932A4
(fr)
|
2009-04-01 |
2012-09-19 |
Merck Sharp & Dohme |
Inhibiteurs de l'activité akt
|
ES2662072T3
(es)
|
2009-05-12 |
2018-04-05 |
Albany Molecular Research, Inc. |
7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y uso de la misma
|
KR20120034644A
(ko)
|
2009-05-12 |
2012-04-12 |
알바니 몰레큘라 리써치, 인크. |
아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
|
EP2429293B1
(fr)
|
2009-05-12 |
2014-10-29 |
Bristol-Myers Squibb Company |
FORMES CRISTALLINES DE (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN -6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE ET LEURS UTILISATIONS
|
KR101485645B1
(ko)
|
2009-10-14 |
2015-01-22 |
머크 샤프 앤드 돔 코포레이션 |
p53 활성을 증가시키는 치환된 피페리딘 및 그의 용도
|
WO2011163330A1
(fr)
|
2010-06-24 |
2011-12-29 |
Merck Sharp & Dohme Corp. |
Nouveaux composés hétérocycliques utilisés comme inhibiteurs de erk
|
CN107090456B
(zh)
|
2010-08-02 |
2022-01-18 |
瑟纳治疗公司 |
使用短干扰核酸的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1基因表达的抑制
|
HUE044815T2
(hu)
|
2010-08-17 |
2019-11-28 |
Sirna Therapeutics Inc |
Hepatitisz B vírus (HBV) génexpressziójának RNS-interferencia közvetített gátlása, rövid interferáló nukleinsav (SINS) alkalmazásával
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
WO2012030685A2
(fr)
|
2010-09-01 |
2012-03-08 |
Schering Corporation |
Dérivés d'indazole utilisables en tant qu'inhibiteurs de la voie erk
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
WO2012058210A1
(fr)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
INHIBITION FACILITÉE PAR L'INTERFÉRENCE D'ARN DE L'EXPRESSION D'UN GÈNE AU MOYEN D'ACIDES NUCLÉIQUES INTERFÉRENTS COURTS (siNA)
|
US9351965B2
(en)
|
2010-12-21 |
2016-05-31 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
CN103732592A
(zh)
|
2011-04-21 |
2014-04-16 |
默沙东公司 |
胰岛素样生长因子-1受体抑制剂
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
EP3919620A1
(fr)
|
2012-05-02 |
2021-12-08 |
Sirna Therapeutics, Inc. |
Compositions d'acide nucléique interférent court (sina)
|
CA2882950A1
(fr)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Nouveaux composes inhibiteurs de erk
|
EP2919788A4
(fr)
|
2012-11-14 |
2016-05-25 |
Univ Johns Hopkins |
Méthodes et compositions pour le traitement de la schizophrénie
|
LT2925888T
(lt)
|
2012-11-28 |
2018-01-10 |
Merck Sharp & Dohme Corp. |
Vėžio gydymo kompozicijos ir būdai
|
BR112015013611A2
(pt)
|
2012-12-20 |
2017-11-14 |
Merck Sharp & Dohme |
composto, e, composição farmacêutica
|
WO2014120748A1
(fr)
|
2013-01-30 |
2014-08-07 |
Merck Sharp & Dohme Corp. |
Purines 2,6,7,8-substituées utilisées en tant qu'inhibiteurs de hdm2
|
US20160194368A1
(en)
|
2013-09-03 |
2016-07-07 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
NL2015865B1
(en)
|
2015-11-27 |
2017-06-13 |
Le Vet B V |
Maropitant Formulation.
|
US10947234B2
(en)
|
2017-11-08 |
2021-03-16 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
US20210309688A1
(en)
|
2018-08-07 |
2021-10-07 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
US20210277009A1
(en)
|
2018-08-07 |
2021-09-09 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
US11098029B2
(en)
|
2019-02-13 |
2021-08-24 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
US20230018413A1
(en)
|
2019-08-08 |
2023-01-19 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
JP7443625B2
(ja)
|
2020-08-18 |
2024-03-05 |
メルク・シャープ・アンド・ドーム・エルエルシー |
ビシクロヘプタンピロリジンオレキシン受容体アゴニスト
|