JPH05394B2 - - Google Patents

Info

Publication number
JPH05394B2
JPH05394B2 JP2138152A JP13815290A JPH05394B2 JP H05394 B2 JPH05394 B2 JP H05394B2 JP 2138152 A JP2138152 A JP 2138152A JP 13815290 A JP13815290 A JP 13815290A JP H05394 B2 JPH05394 B2 JP H05394B2
Authority
JP
Japan
Prior art keywords
formula
alkyl
carbon atoms
group
compound represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2138152A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0314573A (ja
Inventor
Moorisu Ebansu Jon
Edoin Batsukingamu Robin
Uirukotsukusu Kenesu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of JPH0314573A publication Critical patent/JPH0314573A/ja
Publication of JPH05394B2 publication Critical patent/JPH05394B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Glass Compositions (AREA)
JP2138152A 1981-09-25 1990-05-28 化学中間体 Granted JPH0314573A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8129064 1981-09-25
GB8206400 1982-03-04
GB6400 1982-04-08
GB8210490 1982-04-08
GB29064 1982-04-08
GB10490 1982-04-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP16643782A Division JPS5867683A (ja) 1981-09-25 1982-09-24 活性化合物、その製法およびそれを含む医薬組成物

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP4185633A Division JP2504708B2 (ja) 1981-09-25 1992-06-03 化学中間体
JP4185632A Division JP2504707B2 (ja) 1981-09-25 1992-06-03 化学中間体

Publications (2)

Publication Number Publication Date
JPH0314573A JPH0314573A (ja) 1991-01-23
JPH05394B2 true JPH05394B2 (en, 2012) 1993-01-05

Family

ID=27261315

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2138152A Granted JPH0314573A (ja) 1981-09-25 1990-05-28 化学中間体
JP4100440A Expired - Lifetime JPH0780875B2 (ja) 1981-09-25 1992-03-26 活性化合物、その製法およびそれを含む医薬組成物
JP4185632A Expired - Lifetime JP2504707B2 (ja) 1981-09-25 1992-06-03 化学中間体
JP4185633A Expired - Lifetime JP2504708B2 (ja) 1981-09-25 1992-06-03 化学中間体

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP4100440A Expired - Lifetime JPH0780875B2 (ja) 1981-09-25 1992-03-26 活性化合物、その製法およびそれを含む医薬組成物
JP4185632A Expired - Lifetime JP2504707B2 (ja) 1981-09-25 1992-06-03 化学中間体
JP4185633A Expired - Lifetime JP2504708B2 (ja) 1981-09-25 1992-06-03 化学中間体

Country Status (24)

Country Link
US (1) US4446113A (en, 2012)
EP (1) EP0076075B1 (en, 2012)
JP (4) JPH0314573A (en, 2012)
KR (1) KR880001943B1 (en, 2012)
AT (1) ATE23718T1 (en, 2012)
AU (1) AU561536B2 (en, 2012)
CA (1) CA1174682A (en, 2012)
DE (1) DE3274350D1 (en, 2012)
DK (1) DK170165B1 (en, 2012)
ES (4) ES8401061A1 (en, 2012)
FI (1) FI73675C (en, 2012)
GB (1) GB2107706A (en, 2012)
GR (1) GR76732B (en, 2012)
HK (1) HK17588A (en, 2012)
IE (1) IE53875B1 (en, 2012)
MX (3) MX174533B (en, 2012)
MY (1) MY102061A (en, 2012)
NO (4) NO159597C (en, 2012)
NZ (1) NZ201984A (en, 2012)
PH (1) PH18691A (en, 2012)
PL (4) PL141135B1 (en, 2012)
PT (1) PT75598B (en, 2012)
SG (1) SG98587G (en, 2012)
YU (4) YU43279B (en, 2012)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ183551A (en) * 1976-04-02 1978-09-20 Beecham Group Ltd Aminochromanols and pharmaceutical compositions containingthem
DE3364145D1 (de) * 1982-04-08 1986-07-24 Beecham Group Plc Antihypertensive benzopyranols
DE3368629D1 (en) * 1982-04-28 1987-02-05 Beecham Group Plc Novel chromenes and chromans
EP0093534A1 (en) * 1982-04-28 1983-11-09 Beecham Group Plc Novel chromanols
DE3368057D1 (en) * 1982-05-21 1987-01-15 Beecham Group Plc Pharmaceutically active aminobenzopyrans
EP0107423B1 (en) * 1982-10-19 1986-07-23 Beecham Group Plc Novel chromans and chromenes
GB8308062D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8308063D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8308064D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
EP0126367B1 (en) * 1983-05-18 1994-10-12 Beecham Group Plc Chroman and chromene derivatives
GB8313679D0 (en) * 1983-05-18 1983-06-22 Beecham Group Plc Active compounds
EP0150202B1 (en) * 1983-07-27 1988-07-06 Beecham Group Plc Di/tetra-hydroquinolines
EP0139992B1 (en) * 1983-09-01 1988-12-28 Beecham Group Plc Chromanol derivatives
DE3477779D1 (en) * 1983-10-13 1989-05-24 Beecham Group Plc Chroman derivatives
GB8409745D0 (en) * 1984-04-14 1984-05-23 Beecham Group Plc Active compounds
GB8413191D0 (en) * 1984-05-23 1984-06-27 Beecham Group Plc Pharmaceutical composition
EP0172352B1 (en) * 1984-06-22 1990-08-29 Beecham Group Plc Active benzopyran compounds
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8419515D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment
GB8513369D0 (en) * 1985-05-28 1985-07-03 Beecham Group Plc Treatment
EP0205292B1 (en) 1985-06-08 1991-11-06 Beecham Group Plc Pyrano[3,2-c]pyridine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them
EP0218373B1 (en) * 1985-09-11 1990-03-07 Beecham Group Plc Chroman derivatives and analogues having antihypertensive activity
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
WO1988000822A1 (en) * 1986-08-08 1988-02-11 The Upjohn Company Methods, compositions and solutions for treating alopecia
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
DE3726261A1 (de) * 1986-12-23 1988-07-07 Merck Patent Gmbh Chromanderivate
ES2058148T3 (es) * 1987-02-04 1994-11-01 Hoechst Ag N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
IL86798A (en) * 1987-06-23 1992-12-01 Sanofi Sa 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them
FR2617165B1 (fr) * 1987-06-23 1989-12-15 Sanofi Sa Derives du dimethyl-2, 2 chromannol-3
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
FR2625744B1 (fr) * 1988-01-12 1990-07-06 Sanofi Sa Derives du dimethyl-2,2 chromannol-3 procede d'obtention et compositions pharmaceutiques en contenant
FR2628424B1 (fr) * 1988-03-09 1990-12-28 Sanofi Sa Derives du dimethyl-2,2 chromannol-3 procede d'obtention et compositions pharmaceutiques en contenant
US4971982A (en) * 1987-07-06 1990-11-20 Hoffmann-La Roche Inc. Benzopyran derivatives
FR2621587B1 (fr) * 1987-10-12 1990-02-09 Sanofi Sa Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant
IL88035A0 (en) * 1987-10-27 1989-06-30 American Home Prod Benzopyran derivatives,their preparation and pharmaceutical compositions containing them
GB8800199D0 (en) * 1988-01-06 1988-02-10 Beecham Group Plc Pharmaceutical preparation
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
AU3693789A (en) * 1988-05-10 1989-11-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) New ophthalmic preparation for treating glaucoma
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
US4988723A (en) * 1988-06-02 1991-01-29 Fujisawa Pharmaceutical Co., Ltd. Benzopyran derivatives and their use as anti-hypertensives
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
DE3827532A1 (de) * 1988-08-13 1990-03-01 Hoechst Ag 6-aroyl-substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
US5194442A (en) * 1988-09-17 1993-03-16 Hoechst Aktiengesellschaft 2,3,4,5-tetrahydro-1-benzoxepins, the use thereof and pharmaceutical products based on these compounds
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
DE3837809A1 (de) * 1988-11-08 1990-05-10 Merck Patent Gmbh Tetralinderivate
FR2639227A1 (fr) * 1988-11-23 1990-05-25 Sanofi Sa Utilisation de derives du chromane pour le traitement des etats depressifs
ATE120459T1 (de) * 1988-12-13 1995-04-15 Beecham Group Plc Benzopyran und verwandte verbindungen.
DE3901720A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Substituierte benzo(b)pyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
US5162553A (en) * 1989-03-03 1992-11-10 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor
US5066816A (en) * 1989-03-03 1991-11-19 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2h-1-benzopyran compounds and intermediates therefor
DE3918041A1 (de) * 1989-06-02 1990-12-06 Merck Patent Gmbh Chromanderivate
IE63935B1 (en) 1989-06-27 1995-06-28 Chem Pharm Forsch Gmbh Novel thienopyran derivatives a process for their preparation and their use
DE3922392A1 (de) 1989-07-07 1991-01-17 Merck Patent Gmbh Chromanderivate
DE3923839A1 (de) * 1989-07-19 1991-01-31 Beiersdorf Ag Benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5223629A (en) * 1989-07-21 1993-06-29 Alkaloida Vegyeszeti Gyar Process for the preparation of anti-hypertensive benzopyran
HU207861B (en) * 1989-07-21 1993-06-28 Alkaloida Vegyeszeti Gyar Process for producing benzopirane derivative of blood pressure lowering activity
DE3926001A1 (de) * 1989-08-05 1991-02-07 Merck Patent Gmbh Chromanderivate
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
US5254555A (en) * 1989-10-30 1993-10-19 Beecham Group P.L.C. Amino pyrimidin-7-yl substituted benzopyrans for treatment of hypertension
TW224941B (en, 2012) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
EP0430621A3 (en) * 1989-11-29 1992-03-04 Beecham Group P.L.C. Process for the preparation of chiral 3,4-epoxy benzopyrans
WO1991012005A1 (en) * 1990-02-06 1991-08-22 Pfizer Inc. Neuroprotective 3-piperidino-4-hydroxychroman derivatives and analogs
US5273998A (en) * 1990-05-11 1993-12-28 Yoshitomi Pharmaceutical Industries, Ltd. Process for making an optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compound
US5276168A (en) * 1990-06-18 1994-01-04 E. R. Squibb & Sons, Inc. Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
CN1060467A (zh) * 1990-09-25 1992-04-22 武田药品工业株式会社 1，3-苯并嗪衍生物、其生产方法和用途
CA2061179A1 (en) * 1991-02-18 1992-08-19 Ryuji Tsuzuki Oxzazinobenzazole compounds
BR9206845A (pt) * 1991-12-05 1996-01-02 Smithkline Beecham Plc Composto famacêutico
FR2698873B1 (fr) 1992-12-07 1995-02-24 Lipha Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant.
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
HUT72741A (en) * 1992-12-19 1996-05-28 Alkaloida Vegyeszeti Gyar Method for producing benzopyrane derivatives and pharmaceutical compositions containing them
US5416097A (en) * 1993-05-19 1995-05-16 Berlex Laboratories, Inc. Potassium channel activators/openers
WO1995020587A1 (en) * 1994-01-31 1995-08-03 Pfizer Inc. Neuroprotective chroman compounds
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
WO2000067754A1 (en) 1999-05-12 2000-11-16 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1495526A (en) * 1974-05-31 1977-12-21 Beecham Group Ltd Chroman derivatives
GB1548221A (en) * 1976-01-27 1979-07-04 Beecham Group Ltd Trans-4-heterocycyl-3,4-dihydro-2h-benzo pyran-3-ol esters
NZ183551A (en) * 1976-04-02 1978-09-20 Beecham Group Ltd Aminochromanols and pharmaceutical compositions containingthem
GB1511187A (en) * 1976-04-02 1978-05-17 Beecham Group Ltd Chromans
GB1548222A (en) * 1976-12-17 1979-07-04 Beecham Group Ltd Trans-4-heterocyclyl-3,4-dihydro-2h-benzo pyarn-3-ol derivatives
DE2965739D1 (en) * 1978-10-04 1983-07-28 Beecham Group Plc Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them
DE3064285D1 (en) * 1979-09-28 1983-08-25 Beecham Group Plc Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them
ZM7682A1 (en) * 1981-09-25 1983-05-23 Beecham Group Plc Active compounds
EP0093534A1 (en) * 1982-04-28 1983-11-09 Beecham Group Plc Novel chromanols

Also Published As

Publication number Publication date
JP2504708B2 (ja) 1996-06-05
PL141133B1 (en) 1987-06-30
NO159597B (no) 1988-10-10
YU43279B (en) 1989-06-30
ES8500268A1 (es) 1984-10-01
FI823272A0 (fi) 1982-09-23
CA1174682A (en) 1984-09-18
PT75598B (en) 1984-12-10
AU8867582A (en) 1983-03-31
ES522938A0 (es) 1984-09-16
JP2504707B2 (ja) 1996-06-05
NZ201984A (en) 1986-04-11
EP0076075A1 (en) 1983-04-06
PL238342A1 (en) 1985-01-16
FI73675C (fi) 1987-11-09
JPH05202034A (ja) 1993-08-10
YU145484A (en) 1986-06-30
MX174533B (es) 1994-05-24
ES8407491A1 (es) 1984-09-16
NO823247L (no) 1983-03-28
NO834134L (no) 1983-03-28
ES522937A0 (es) 1984-09-16
YU44767B (en) 1991-02-28
IE822313L (en) 1983-03-25
YU145384A (en) 1986-06-30
PL141134B1 (en) 1987-06-30
PL141135B1 (en) 1987-06-30
GR76732B (en, 2012) 1984-08-30
MY102061A (en) 1992-03-31
HK17588A (en) 1988-03-11
YU210182A (en) 1984-12-31
ES522939A0 (es) 1984-10-01
DK424582A (da) 1983-03-26
DE3274350D1 (en) 1987-01-08
NO834135L (no) 1983-03-28
ES8407490A1 (es) 1984-09-16
DK170165B1 (da) 1995-06-06
JPH0314573A (ja) 1991-01-23
ATE23718T1 (de) 1986-12-15
YU44768B (en) 1991-02-28
PH18691A (en) 1985-09-05
JPH05301866A (ja) 1993-11-16
NO159597C (no) 1989-01-18
YU145284A (en) 1986-06-30
IE53875B1 (en) 1989-03-29
ES515921A0 (es) 1983-11-16
JPH05310729A (ja) 1993-11-22
JPH0780875B2 (ja) 1995-08-30
PL141099B1 (en) 1987-06-30
FI823272L (fi) 1983-03-26
PL247746A1 (en) 1985-01-30
PL247747A1 (en) 1985-04-24
MX174532B (es) 1994-05-24
US4446113A (en) 1984-05-01
ES8401061A1 (es) 1983-11-16
US4446113B1 (en, 2012) 1985-12-10
KR840001572A (ko) 1984-05-07
FI73675B (fi) 1987-07-31
NO834133L (no) 1983-03-28
YU44766B (en) 1991-02-28
PL247748A1 (en) 1985-04-24
SG98587G (en) 1988-07-15
GB2107706A (en) 1983-05-05
KR880001943B1 (ko) 1988-10-04
MX174531B (es) 1994-05-24
EP0076075B1 (en) 1986-11-20
AU561536B2 (en) 1987-05-14
PT75598A (en) 1982-10-01

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