JPH0128746B2 - - Google Patents

Info

Publication number
JPH0128746B2
JPH0128746B2 JP56060677A JP6067781A JPH0128746B2 JP H0128746 B2 JPH0128746 B2 JP H0128746B2 JP 56060677 A JP56060677 A JP 56060677A JP 6067781 A JP6067781 A JP 6067781A JP H0128746 B2 JPH0128746 B2 JP H0128746B2
Authority
JP
Japan
Prior art keywords
group
alkyl
halogen atom
optionally substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56060677A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57175166A (en
Inventor
Tetsuji Myano
Kunio Suzuki
Nobuo Harada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Priority to JP56060677A priority Critical patent/JPS57175166A/ja
Priority to US06/366,137 priority patent/US4404378A/en
Priority to DE8282103144T priority patent/DE3277809D1/de
Priority to EP82103144A priority patent/EP0063747B1/en
Priority to AT82103144T priority patent/ATE31297T1/de
Priority to HU821210A priority patent/HU186583B/hu
Priority to SU823425004A priority patent/SU1097195A3/ru
Priority to KR8201797A priority patent/KR890001147B1/ko
Publication of JPS57175166A publication Critical patent/JPS57175166A/ja
Priority to SU833585893A priority patent/SU1169531A3/ru
Publication of JPH0128746B2 publication Critical patent/JPH0128746B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56060677A 1981-04-23 1981-04-23 Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation Granted JPS57175166A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP56060677A JPS57175166A (en) 1981-04-23 1981-04-23 Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation
US06/366,137 US4404378A (en) 1981-04-23 1982-04-06 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines
DE8282103144T DE3277809D1 (en) 1981-04-23 1982-04-14 2-substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines
EP82103144A EP0063747B1 (en) 1981-04-23 1982-04-14 2-substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines
AT82103144T ATE31297T1 (de) 1981-04-23 1982-04-14 2-substituierte oder nicht-substituierte aminocarbonyloxyalkyl-1,4-dihydropyridine.
HU821210A HU186583B (en) 1981-04-23 1982-04-20 Process for producing new 2-bracket-substituted or free-bracket closed-amino-carbonyl-oxy-alkyl-1,4-dihydro-pyridine derivatives
SU823425004A SU1097195A3 (ru) 1981-04-23 1982-04-22 Способ получени производных 2-аминокарбонилоксиалкил-1,4-дигидропиридина
KR8201797A KR890001147B1 (ko) 1981-04-23 1982-04-23 2-치환 또는 비치환된 아미노카르보닐 옥시알킬-1,4-디히드로피리딘류의 제조방법
SU833585893A SU1169531A3 (ru) 1981-04-23 1983-04-26 Способ получени 2-замещенных или незамещенных аминокарбонилоксиалкил-1,4-дигидропиридинов

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56060677A JPS57175166A (en) 1981-04-23 1981-04-23 Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS57175166A JPS57175166A (en) 1982-10-28
JPH0128746B2 true JPH0128746B2 (en, 2012) 1989-06-05

Family

ID=13149184

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56060677A Granted JPS57175166A (en) 1981-04-23 1981-04-23 Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation

Country Status (8)

Country Link
US (1) US4404378A (en, 2012)
EP (1) EP0063747B1 (en, 2012)
JP (1) JPS57175166A (en, 2012)
KR (1) KR890001147B1 (en, 2012)
AT (1) ATE31297T1 (en, 2012)
DE (1) DE3277809D1 (en, 2012)
HU (1) HU186583B (en, 2012)
SU (2) SU1097195A3 (en, 2012)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE50987T1 (de) * 1982-05-10 1990-03-15 Takeda Chemical Industries Ltd Dihydropyridinderivate, deren herstellung und verwendung.
DE3363743D1 (en) * 1982-07-22 1986-07-03 Pfizer Ltd Dihydropyridine anti-ischaemic and antihypertensive agents
HU192166B (en) * 1982-08-06 1987-05-28 Banyu Pharma Co Ltd Process for producing 2-carbamoyl-oxy-alkyl-1,4-dihydro-pyridine derivatives
JPS60120861A (ja) * 1983-12-02 1985-06-28 Otsuka Pharmaceut Co Ltd ジヒドロピリジン誘導体
GB8401288D0 (en) * 1984-01-18 1984-02-22 Pfizer Ltd Therapeutic agents
US4672068A (en) * 1984-05-04 1987-06-09 Fujirebio Kabushiki Kaisha Antihypertensive 1,4-dihydropyridines having a conjugated ester
IT1201476B (it) * 1985-10-04 1989-02-02 Yason Srl Derivato diidropiridinico,procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
IT1197012B (it) * 1986-07-29 1988-11-25 Boehringer Biochemia Srl 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
DE2658183A1 (de) 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2844595A1 (de) 1978-10-13 1980-04-30 Bayer Ag Acylaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DE3277809D1 (en) 1988-01-21
SU1169531A3 (ru) 1985-07-23
SU1097195A3 (ru) 1984-06-07
KR830010074A (ko) 1983-12-26
US4404378A (en) 1983-09-13
EP0063747A1 (en) 1982-11-03
JPS57175166A (en) 1982-10-28
EP0063747B1 (en) 1987-12-09
HU186583B (en) 1985-08-28
KR890001147B1 (ko) 1989-04-25
ATE31297T1 (de) 1987-12-15

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