ATE31297T1 - 2-substituierte oder nicht-substituierte aminocarbonyloxyalkyl-1,4-dihydropyridine. - Google Patents
2-substituierte oder nicht-substituierte aminocarbonyloxyalkyl-1,4-dihydropyridine.Info
- Publication number
- ATE31297T1 ATE31297T1 AT82103144T AT82103144T ATE31297T1 AT E31297 T1 ATE31297 T1 AT E31297T1 AT 82103144 T AT82103144 T AT 82103144T AT 82103144 T AT82103144 T AT 82103144T AT E31297 T1 ATE31297 T1 AT E31297T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- lower alkyl
- alkyl
- cyano
- nitro
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- -1 aralkyloxyalkyl Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005160 aryl oxy alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000024883 vasodilation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56060677A JPS57175166A (en) | 1981-04-23 | 1981-04-23 | Carbamoyloxyalkyl-1,4-dihydropyridine derivative and its preparation |
| EP82103144A EP0063747B1 (en) | 1981-04-23 | 1982-04-14 | 2-substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE31297T1 true ATE31297T1 (de) | 1987-12-15 |
Family
ID=13149184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82103144T ATE31297T1 (de) | 1981-04-23 | 1982-04-14 | 2-substituierte oder nicht-substituierte aminocarbonyloxyalkyl-1,4-dihydropyridine. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4404378A (en, 2012) |
| EP (1) | EP0063747B1 (en, 2012) |
| JP (1) | JPS57175166A (en, 2012) |
| KR (1) | KR890001147B1 (en, 2012) |
| AT (1) | ATE31297T1 (en, 2012) |
| DE (1) | DE3277809D1 (en, 2012) |
| HU (1) | HU186583B (en, 2012) |
| SU (2) | SU1097195A3 (en, 2012) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE50987T1 (de) * | 1982-05-10 | 1990-03-15 | Takeda Chemical Industries Ltd | Dihydropyridinderivate, deren herstellung und verwendung. |
| DE3363743D1 (en) * | 1982-07-22 | 1986-07-03 | Pfizer Ltd | Dihydropyridine anti-ischaemic and antihypertensive agents |
| HU192166B (en) * | 1982-08-06 | 1987-05-28 | Banyu Pharma Co Ltd | Process for producing 2-carbamoyl-oxy-alkyl-1,4-dihydro-pyridine derivatives |
| JPS60120861A (ja) * | 1983-12-02 | 1985-06-28 | Otsuka Pharmaceut Co Ltd | ジヒドロピリジン誘導体 |
| GB8401288D0 (en) * | 1984-01-18 | 1984-02-22 | Pfizer Ltd | Therapeutic agents |
| US4672068A (en) * | 1984-05-04 | 1987-06-09 | Fujirebio Kabushiki Kaisha | Antihypertensive 1,4-dihydropyridines having a conjugated ester |
| IT1201476B (it) * | 1985-10-04 | 1989-02-02 | Yason Srl | Derivato diidropiridinico,procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono |
| IT1197012B (it) * | 1986-07-29 | 1988-11-25 | Boehringer Biochemia Srl | 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1552911A (en) | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
| DE2658183A1 (de) | 1976-12-22 | 1978-07-06 | Bayer Ag | In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2844595A1 (de) | 1978-10-13 | 1980-04-30 | Bayer Ag | Acylaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1981
- 1981-04-23 JP JP56060677A patent/JPS57175166A/ja active Granted
-
1982
- 1982-04-06 US US06/366,137 patent/US4404378A/en not_active Expired - Lifetime
- 1982-04-14 EP EP82103144A patent/EP0063747B1/en not_active Expired
- 1982-04-14 DE DE8282103144T patent/DE3277809D1/de not_active Expired
- 1982-04-14 AT AT82103144T patent/ATE31297T1/de active
- 1982-04-20 HU HU821210A patent/HU186583B/hu not_active IP Right Cessation
- 1982-04-22 SU SU823425004A patent/SU1097195A3/ru active
- 1982-04-23 KR KR8201797A patent/KR890001147B1/ko not_active Expired
-
1983
- 1983-04-26 SU SU833585893A patent/SU1169531A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| DE3277809D1 (en) | 1988-01-21 |
| SU1169531A3 (ru) | 1985-07-23 |
| SU1097195A3 (ru) | 1984-06-07 |
| KR830010074A (ko) | 1983-12-26 |
| US4404378A (en) | 1983-09-13 |
| EP0063747A1 (en) | 1982-11-03 |
| JPS57175166A (en) | 1982-10-28 |
| EP0063747B1 (en) | 1987-12-09 |
| HU186583B (en) | 1985-08-28 |
| JPH0128746B2 (en, 2012) | 1989-06-05 |
| KR890001147B1 (ko) | 1989-04-25 |
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