JP7009466B2 - アンドロゲン受容体の標的分解のための化合物および方法 - Google Patents

アンドロゲン受容体の標的分解のための化合物および方法 Download PDF

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JP7009466B2
JP7009466B2 JP2019519731A JP2019519731A JP7009466B2 JP 7009466 B2 JP7009466 B2 JP 7009466B2 JP 2019519731 A JP2019519731 A JP 2019519731A JP 2019519731 A JP2019519731 A JP 2019519731A JP 7009466 B2 JP7009466 B2 JP 7009466B2
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alkyl
chloro
cyanophenoxy
tetramethylcyclobutyl
dioxopiperidine
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JP2019530715A (ja
JP2019530715A5 (enExample
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クルー，アンドリュー・ピィ
ホーンバーガー，キース・アール
スナイダー，ローレンス・ビィ
ジマーマン，カート
ワン，ジン
バーリン，マイケル
クルース，クレイグ・エム
ドン，ハンチン
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Arvinas Operations Inc
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Arvinas Operations Inc
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    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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JP2019519731A 2016-10-11 2017-10-11 アンドロゲン受容体の標的分解のための化合物および方法 Active JP7009466B2 (ja)

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JP2020032037A JP6972210B2 (ja) 2016-10-11 2020-02-27 アンドロゲン受容体の標的分解のための化合物および方法
JP2021198476A JP7203936B2 (ja) 2016-10-11 2021-12-07 アンドロゲン受容体の標的分解のための化合物および方法

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US201662406888P 2016-10-11 2016-10-11
US62/406,888 2016-10-11
US201762528385P 2017-07-03 2017-07-03
US62/528,385 2017-07-03
PCT/US2017/056234 WO2018071606A1 (en) 2016-10-11 2017-10-11 Compounds and methods for the targeted degradation of androgen receptor

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JP2021198476A Active JP7203936B2 (ja) 2016-10-11 2021-12-07 アンドロゲン受容体の標的分解のための化合物および方法
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