JP6942148B2 - 試料に対する光学測定の実施 - Google Patents
試料に対する光学測定の実施 Download PDFInfo
- Publication number
- JP6942148B2 JP6942148B2 JP2018558180A JP2018558180A JP6942148B2 JP 6942148 B2 JP6942148 B2 JP 6942148B2 JP 2018558180 A JP2018558180 A JP 2018558180A JP 2018558180 A JP2018558180 A JP 2018558180A JP 6942148 B2 JP6942148 B2 JP 6942148B2
- Authority
- JP
- Japan
- Prior art keywords
- sample
- measurement
- blood
- determining
- measured
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/06—Investigating concentration of particle suspensions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/011—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells with lysing, e.g. of erythrocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/016—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
- G01N2021/8592—Grain or other flowing solid samples
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Ecology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Zoology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021145455A JP7253014B2 (ja) | 2016-05-11 | 2021-09-07 | 試料に対する光学測定の実施 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662334517P | 2016-05-11 | 2016-05-11 | |
| US62/334,517 | 2016-05-11 | ||
| PCT/IL2017/050526 WO2017195208A1 (en) | 2016-05-11 | 2017-05-11 | Performing optical measurements on a sample |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021145455A Division JP7253014B2 (ja) | 2016-05-11 | 2021-09-07 | 試料に対する光学測定の実施 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019522774A JP2019522774A (ja) | 2019-08-15 |
| JP2019522774A5 JP2019522774A5 (enExample) | 2020-06-18 |
| JP6942148B2 true JP6942148B2 (ja) | 2021-09-29 |
Family
ID=59014682
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018558180A Active JP6942148B2 (ja) | 2016-05-11 | 2017-05-11 | 試料に対する光学測定の実施 |
| JP2021145455A Active JP7253014B2 (ja) | 2016-05-11 | 2021-09-07 | 試料に対する光学測定の実施 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021145455A Active JP7253014B2 (ja) | 2016-05-11 | 2021-09-07 | 試料に対する光学測定の実施 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US11099175B2 (enExample) |
| EP (1) | EP3455626B1 (enExample) |
| JP (2) | JP6942148B2 (enExample) |
| CN (2) | CN109564209B (enExample) |
| AU (1) | AU2017263807B2 (enExample) |
| CA (1) | CA3022770A1 (enExample) |
| WO (1) | WO2017195208A1 (enExample) |
| ZA (1) | ZA201807687B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| WO2013098821A1 (en) | 2011-12-29 | 2013-07-04 | Parasight Ltd. | Methods and systems for detecting a pathogen in a biological sample |
| WO2014188405A1 (en) | 2013-05-23 | 2014-11-27 | Parasight Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
| EP3039477B1 (en) | 2013-08-26 | 2021-10-20 | S.D. Sight Diagnostics Ltd. | Digital microscopy systems, methods and computer program products |
| EP3155558A1 (en) * | 2014-06-16 | 2017-04-19 | Siemens Healthcare Diagnostics Inc. | Analyzing digital holographic microscopy data for hematology applications |
| US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| US12005441B1 (en) | 2014-11-26 | 2024-06-11 | Medica Corporation | Automated microscopic cell analysis |
| US10625259B1 (en) | 2014-11-26 | 2020-04-21 | Medica Corporation | Automated microscopic cell analysis |
| EP3859425B1 (en) | 2015-09-17 | 2024-04-17 | S.D. Sight Diagnostics Ltd. | Methods and apparatus for detecting an entity in a bodily sample |
| CA3018536A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinguishing between blood sample components |
| EP3455626B1 (en) | 2016-05-11 | 2025-08-06 | S.D. Sight Diagnostics Ltd. | Performing optical measurements on a sample |
| EP4177593A1 (en) | 2016-05-11 | 2023-05-10 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| WO2019035079A1 (en) | 2017-08-17 | 2019-02-21 | Abbott Point Of Care Inc. | DEVICES, SYSTEMS AND METHODS FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS |
| WO2019035077A1 (en) | 2017-08-17 | 2019-02-21 | Abbott Point Of Care Inc. | DEVICES, SYSTEMS AND METHODS FOR PERFORMING OPTICAL ASSAYS |
| CN110869746B (zh) | 2017-08-17 | 2023-08-11 | 雅培医护站股份有限公司 | 利用通用电路系统执行光学和电化学测定的技术 |
| CN111788471B (zh) | 2017-11-14 | 2023-12-12 | 思迪赛特诊断有限公司 | 用于光学测量的样品载体 |
| US11047845B1 (en) | 2017-11-15 | 2021-06-29 | Medica Corporation | Control material and methods for cell analyzers |
| MX2022004703A (es) | 2019-10-22 | 2022-05-11 | S D Sight Diagnostics Ltd | Contabilidad de errores en mediciones opticas. |
| EP4073492A1 (en) | 2019-12-12 | 2022-10-19 | S.D. Sight Diagnostics Ltd. | Analyzing an analyte disposed within a medium |
| MX2022007121A (es) | 2019-12-12 | 2022-07-11 | S D Sight Diagnostics Ltd | Imagenes microscopicas desenfocadas de una muestra. |
| CA3160702A1 (en) | 2019-12-12 | 2021-06-17 | S.D. Sight Diagnostics Ltd | Artificial generation of a color blood smear image |
| BR112022011233A2 (pt) | 2019-12-12 | 2022-08-30 | S D Sight Diagnostics Ltd | Detecção de plaquetas em uma amostra sanguínea |
| BR112022011338A2 (pt) | 2019-12-12 | 2022-08-23 | S D Sight Diagnostics Ltd | Modelos de classificação para analisar uma amostra |
| WO2021134508A1 (zh) * | 2019-12-31 | 2021-07-08 | 深圳迈瑞生物医疗电子股份有限公司 | 一种细胞图像分析装置和样本分析方法 |
| US11865270B2 (en) * | 2020-01-16 | 2024-01-09 | Starling Medical, Inc. | Bodily fluid management system |
| WO2022009104A2 (en) | 2020-07-07 | 2022-01-13 | S.D. Sight Diagnostics Ltd | Focusing a microscope using fluorescent images |
| CN114152557B (zh) * | 2021-11-16 | 2024-04-30 | 深圳元视医学科技有限公司 | 基于图像分析的血细胞计数方法和系统 |
| EP4469204A1 (en) | 2022-01-25 | 2024-12-04 | S.D. Sight Diagnostics Ltd. | Sample carrier for use with a bodily sample |
| CN114778418B (zh) * | 2022-06-17 | 2022-09-27 | 深圳安侣医学科技有限公司 | 基于显微放大数字图像的血红蛋白分析方法及系统 |
| GB202218615D0 (en) | 2022-12-12 | 2023-01-25 | S D Sight Diagnostics Ltd | System and method for analyzing bodily samples |
| EP4713685A1 (en) | 2023-05-18 | 2026-03-25 | S.D. Sight Diagnostics Ltd. | Apparatus and methods for microscopic analysis of a biological sample |
| WO2025120470A1 (en) | 2023-12-04 | 2025-06-12 | S.D. Sight Diagnostics Ltd | Varying spatial coherence in a microscope system |
| CN118962158B (zh) * | 2024-07-26 | 2025-05-02 | 湖北携康智能医学科技有限公司 | 一种血红蛋白检测分析仪器 |
Family Cites Families (409)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3203768A (en) | 1961-08-01 | 1965-08-31 | Westinghouse Electric Corp | Apparatus of zone refining and controlling solute segregation in solidifying melts by electromagnetic means |
| US3603156A (en) | 1970-02-04 | 1971-09-07 | Gradko Glass Lab Inc | Disposable dilution system |
| US3676076A (en) | 1970-09-24 | 1972-07-11 | Gradko Glass Lab Inc | Disposable container |
| GB1324323A (en) | 1971-02-05 | 1973-07-25 | Image Analysing Computers Ltd | Automatic focusing of an optical image |
| US3967056A (en) | 1973-02-26 | 1976-06-29 | Minolta Camera Kabushiki Kaisha | Automatic focusing apparatus |
| US3916205A (en) | 1973-05-31 | 1975-10-28 | Block Engineering | Differential counting of leukocytes and other cells |
| JPS5916667B2 (ja) * | 1975-02-28 | 1984-04-17 | トウアイヨウデンシ カブシキガイシヤ | 自動血液分析装置 |
| US4076419A (en) | 1976-07-12 | 1978-02-28 | Kleker Richard G | Method and apparatus for hematology |
| US4209548A (en) | 1976-11-01 | 1980-06-24 | Rush-Presbyterian-St. Luke's Medical Center | Method for the preparation of blood samples for automated analysis |
| US4097845A (en) | 1976-11-01 | 1978-06-27 | Rush-Presbyterian-St. Luke's Medical Center | Method of and an apparatus for automatic classification of red blood cells |
| US4199748A (en) | 1976-11-01 | 1980-04-22 | Rush-Presbyterian-St. Luke's Medical Center | Automated method and apparatus for classification of cells with application to the diagnosis of anemia |
| DE2910875C2 (de) | 1979-03-20 | 1985-11-14 | Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe | Verfahren zur automatischen Scharfeinstellung |
| US4453266A (en) | 1980-04-21 | 1984-06-05 | Rush-Presbyterian-St. Luke's Medical Center | Method and apparatus for measuring mean cell volume of red blood cells |
| ES8307122A1 (es) | 1981-08-27 | 1983-06-16 | Becton Dickinson Co | "perfeccionamientos introducidos en un aparato para introducir reactivos en recipientes de recogida de muestras". |
| US4454235A (en) | 1982-06-01 | 1984-06-12 | Miles Laboratories, Inc. | Capillary tube holder for liquid transfer in immunoassay |
| US4494479A (en) | 1982-10-14 | 1985-01-22 | Coulter Electronics, Inc. | Slide preparation apparatus |
| DE3486488T2 (de) | 1983-01-10 | 2003-04-03 | Gen-Probe Inc., San Diego | Verfahren zum Nachweis, Identifizieren und Quantifizieren von Organismen und Viren |
| US4580895A (en) | 1983-10-28 | 1986-04-08 | Dynatech Laboratories, Incorporated | Sample-scanning photometer |
| JPS60162955A (ja) | 1984-02-03 | 1985-08-24 | Hitachi Ltd | 血球自動分析装置 |
| EP0183717B1 (en) | 1984-05-15 | 1989-11-23 | Cytocolor Inc. | Single dye replacement for romanowsky plural dye variable compositions in human biopsy specimen constituent identifications |
| US4700298A (en) | 1984-09-14 | 1987-10-13 | Branko Palcic | Dynamic microscope image processing scanner |
| JPS61198204A (ja) | 1985-02-28 | 1986-09-02 | Disco Abrasive Sys Ltd | 顕微鏡のオ−トフオ−カス方法 |
| US5164598A (en) | 1985-08-05 | 1992-11-17 | Biotrack | Capillary flow device |
| US4761381A (en) | 1985-09-18 | 1988-08-02 | Miles Inc. | Volume metering capillary gap device for applying a liquid sample onto a reactive surface |
| DE3707487A1 (de) | 1986-05-16 | 1987-11-26 | Reichert Optische Werke Ag | Verfahren zur autofokussierung von mikroskopen und mikroskope mit einer autofokussierung |
| JPH0774856B2 (ja) | 1986-10-16 | 1995-08-09 | オリンパス光学工業株式会社 | 自動焦点調節方法 |
| US4774192A (en) | 1987-01-28 | 1988-09-27 | Technimed Corporation | A dry reagent delivery system with membrane having porosity gradient |
| US4849340A (en) | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
| US4849430A (en) | 1988-03-09 | 1989-07-18 | Monsanto Company | Method of inhibiting virus |
| US6262798B1 (en) | 1992-09-29 | 2001-07-17 | Board Of Regents, The University Of Texas System | Method and apparatus for direct spectrophotometric measurements in unaltered whole blood |
| US5001067A (en) | 1989-09-18 | 1991-03-19 | Nova Biomedical Corporation | Determining the concentration of water soluble species in biological fluid |
| US5064282A (en) | 1989-09-26 | 1991-11-12 | Artel, Inc. | Photometric apparatus and method for measuring hemoglobin |
| US5229265A (en) | 1990-03-13 | 1993-07-20 | Litron Laboratories | Process for analyzing clastogenic agents |
| US5427959A (en) | 1990-10-01 | 1995-06-27 | Canon Kabushiki Kaisha | Apparatus and method for measuring specimen |
| EP0628167B1 (en) | 1992-02-24 | 2000-08-23 | Coulter Corporation | Hematology control composition for leukocyte analogs; and methods for their preparation and use |
| US5331958A (en) | 1992-03-31 | 1994-07-26 | University Of Manitoba | Spectrophotometric blood analysis |
| US5430542A (en) | 1992-04-10 | 1995-07-04 | Avox Systems, Inc. | Disposable optical cuvette |
| US5342790A (en) | 1992-10-30 | 1994-08-30 | Becton Dickinson And Company | Apparatus for indirect fluorescent assay of blood samples |
| DE69424079T2 (de) | 1993-02-22 | 2000-09-07 | Sysmex Corp., Kobe | Ein Reagenz zum Nachweis von malariainfizierten Zellen und ein Nachweis-Verfahren für malariainfizierte Zellen unter Verwendung desselben |
| US5483055A (en) | 1994-01-18 | 1996-01-09 | Thompson; Timothy V. | Method and apparatus for performing an automatic focus operation for a microscope |
| JP5161052B2 (ja) | 2008-12-04 | 2013-03-13 | オリンパス株式会社 | 顕微鏡システム、標本観察方法およびプログラム |
| US5590660A (en) | 1994-03-28 | 1997-01-07 | Xillix Technologies Corp. | Apparatus and method for imaging diseased tissue using integrated autofluorescence |
| US5782770A (en) | 1994-05-12 | 1998-07-21 | Science Applications International Corporation | Hyperspectral imaging methods and apparatus for non-invasive diagnosis of tissue for cancer |
| JPH07325247A (ja) | 1994-05-31 | 1995-12-12 | Nikon Corp | 自動合焦装置 |
| US5932872A (en) | 1994-07-01 | 1999-08-03 | Jeffrey H. Price | Autofocus system for scanning microscopy having a volume image formation |
| DK0834758T3 (da) | 1994-07-01 | 1999-12-13 | Jeffrey H Price | Kontinuerligt volumenafbildningssystem til scanningmikroskopi |
| US5499097A (en) | 1994-09-19 | 1996-03-12 | Neopath, Inc. | Method and apparatus for checking automated optical system performance repeatability |
| US5978497A (en) | 1994-09-20 | 1999-11-02 | Neopath, Inc. | Apparatus for the identification of free-lying cells |
| US5566249A (en) | 1994-09-20 | 1996-10-15 | Neopath, Inc. | Apparatus for detecting bubbles in coverslip adhesive |
| WO1996012981A1 (en) | 1994-10-21 | 1996-05-02 | Kla Instruments Corporation | Autofocusing apparatus and method for high resolution microscope system |
| AU4131796A (en) | 1994-10-27 | 1996-05-23 | Entremed, Inc | Identification of infection with flow cytometry |
| EP0713087B1 (en) | 1994-11-17 | 1999-04-14 | Chemunex | Apparatus and process for rapid and ultrasensitive detection and counting of microorganisms by fluorescence |
| SE504193C2 (sv) | 1995-04-21 | 1996-12-02 | Hemocue Ab | Kapillär mikrokyvett |
| JPH08313340A (ja) | 1995-05-23 | 1996-11-29 | Eresu Trading Kk | 紫外線測定シート及び紫外線測定機能付き日焼け装置 |
| US5625706A (en) | 1995-05-31 | 1997-04-29 | Neopath, Inc. | Method and apparatus for continously monitoring and forecasting slide and specimen preparation for a biological specimen population |
| US5671288A (en) | 1995-05-31 | 1997-09-23 | Neopath, Inc. | Method and apparatus for assessing slide and specimen preparation quality |
| US5985595A (en) | 1995-06-07 | 1999-11-16 | The University Of Connecticut | Early detection of Borrelia infection |
| JP3640712B2 (ja) * | 1995-08-11 | 2005-04-20 | 衛 石澤 | 血小板検査方法及び血小板検査用採血管 |
| BR9611136A (pt) * | 1995-10-23 | 1999-09-14 | Cytometrics Inc | Processo e aparelho para análise de imagem refletida |
| US5670240A (en) | 1995-11-09 | 1997-09-23 | Flex Products, Inc. | Embossed substrate and photoreceptor device incorporating the same and method |
| US6005964A (en) | 1996-01-24 | 1999-12-21 | The Board Of Trustees Of The University Of Illinois | Automatic machine vision microscope slide inspection system and method |
| KR0165522B1 (ko) | 1996-05-23 | 1999-03-20 | 김광호 | 혈증성분 무혈진단을 위한 최적지점 검색장치및 이를 이용한 무혈진단기 |
| GB9620934D0 (en) | 1996-10-08 | 1996-11-27 | Molecular Drives Limited | Multi-well containers |
| AU739824B2 (en) | 1997-05-05 | 2001-10-18 | Chemometec A/S | A method and a system for determination of particles in a liquid sample |
| US6074879A (en) | 1997-06-23 | 2000-06-13 | Bayer Corporation | Synthetic polymer particles for use as standards and calibrators in flow cytometry |
| JPH1173903A (ja) | 1997-08-28 | 1999-03-16 | Jeol Ltd | 走査電子顕微鏡のオートフォーカス方法 |
| GB2329014A (en) | 1997-09-05 | 1999-03-10 | Colin Campbell | Automated identification of tubercle bacilli |
| US6064474A (en) | 1998-02-06 | 2000-05-16 | Optical Sensors, Inc. | Optical measurement of blood hematocrit incorporating a self-calibration algorithm |
| US20020028471A1 (en) | 1998-02-20 | 2002-03-07 | Oberhardt Bruce J. | Cell analysis methods and apparatus |
| US6929953B1 (en) | 1998-03-07 | 2005-08-16 | Robert A. Levine | Apparatus for analyzing biologic fluids |
| US6350613B1 (en) | 1998-03-07 | 2002-02-26 | Belton Dickinson & Co. | Determination of white blood cell differential and reticulocyte counts |
| US5948686A (en) | 1998-03-07 | 1999-09-07 | Robert A. Leuine | Method for performing blood cell counts |
| US6723290B1 (en) | 1998-03-07 | 2004-04-20 | Levine Robert A | Container for holding biologic fluid for analysis |
| US6235536B1 (en) | 1998-03-07 | 2001-05-22 | Robert A. Levine | Analysis of quiescent anticoagulated whole blood samples |
| US6027695A (en) | 1998-04-01 | 2000-02-22 | Dupont Pharmaceuticals Company | Apparatus for holding small volumes of liquids |
| KR20010083041A (ko) | 1998-06-02 | 2001-08-31 | 추후 | 파수 도메인 반사측정과 배경 진폭 감소 및 보상을 사용한공초점 간섭 마이크로스코피용 방법 및 장치 |
| IT1304854B1 (it) | 1998-07-29 | 2001-04-05 | Paolo Fazii | Metodo di differenziazione cromatica dei microrganismi in fluorescenza |
| US6132685A (en) | 1998-08-10 | 2000-10-17 | Caliper Technologies Corporation | High throughput microfluidic systems and methods |
| US6320979B1 (en) | 1998-10-06 | 2001-11-20 | Canon Kabushiki Kaisha | Depth of field enhancement |
| US6496260B1 (en) | 1998-12-23 | 2002-12-17 | Molecular Devices Corp. | Vertical-beam photometer for determination of light absorption pathlength |
| JP2000199845A (ja) | 1999-01-05 | 2000-07-18 | Ricoh Co Ltd | 自動合焦装置及び自動合焦方法 |
| US6330348B1 (en) | 1999-01-21 | 2001-12-11 | Resolution Sciences Corporation | Method and apparatus for measurement of microtome performance |
| US8406498B2 (en) | 1999-01-25 | 2013-03-26 | Amnis Corporation | Blood and cell analysis using an imaging flow cytometer |
| US6344340B1 (en) | 1999-03-01 | 2002-02-05 | Novus International, Inc. | Viability assay for sporocyst-forming protozoa |
| US6582964B1 (en) | 1999-05-12 | 2003-06-24 | Cme Telemetrix Inc. | Method and apparatus for rapid measurement of HbA1c |
| US7034883B1 (en) | 1999-08-10 | 2006-04-25 | Cellavision Ab | Automatic focusing |
| US6711516B2 (en) | 1999-11-23 | 2004-03-23 | Spectromedical Inc. | Method for calibrating spectrophotometric apparatus |
| US6611777B2 (en) | 1999-11-23 | 2003-08-26 | James Samsoondar | Method for calibrating spectrophotometric apparatus |
| US6949384B2 (en) | 2001-12-21 | 2005-09-27 | Spectromedical Inc. | Method for monitoring degradation of Hb-based blood substitutes |
| DE60038127T2 (de) | 2000-01-06 | 2009-03-05 | Caliper Life Sciences, Inc., Mountain View | Methoden und syteme zur überwachung intrazellulärer bindereaktionen |
| JP3516918B2 (ja) | 2000-01-19 | 2004-04-05 | 株式会社日立国際電気 | 半導体装置の製造方法及び半導体製造装置 |
| US6836559B2 (en) | 2000-03-09 | 2004-12-28 | The Regents Of The University Of California | Automated video-microscopic imaging and data acquisition system for colloid deposition measurements |
| AU2001251539A1 (en) | 2000-04-11 | 2001-10-23 | Cornell Research Foundation Inc. | System and method for three-dimensional image rendering and analysis |
| US6711283B1 (en) | 2000-05-03 | 2004-03-23 | Aperio Technologies, Inc. | Fully automatic rapid microscope slide scanner |
| US7668362B2 (en) | 2000-05-03 | 2010-02-23 | Aperio Technologies, Inc. | System and method for assessing virtual slide image quality |
| US6799119B1 (en) | 2000-05-15 | 2004-09-28 | Colorado School Of Mines | Method for detection of biological related materials using biomarkers |
| US6554788B1 (en) | 2000-06-02 | 2003-04-29 | Cobe Cardiovascular, Inc. | Hematocrit sampling system |
| US7630063B2 (en) | 2000-08-02 | 2009-12-08 | Honeywell International Inc. | Miniaturized cytometer for detecting multiple species in a sample |
| US6834237B2 (en) | 2000-06-02 | 2004-12-21 | Medicometrics Aps | Method and system for classifying a biological sample |
| US6632681B1 (en) | 2000-07-24 | 2003-10-14 | Ey Laboratories | Reagent delivery device and method of use |
| US6819408B1 (en) | 2000-09-27 | 2004-11-16 | Becton, Dickinson And Company | Method for obtaining a monolayer of desired particles in a liquid sample |
| US6448024B1 (en) | 2000-10-03 | 2002-09-10 | Roche Diagnostics Corporation | Method, reagent, cartridge, and device for determining fibrinogen |
| US20100261159A1 (en) | 2000-10-10 | 2010-10-14 | Robert Hess | Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof |
| US7027628B1 (en) | 2000-11-14 | 2006-04-11 | The United States Of America As Represented By The Department Of Health And Human Services | Automated microscopic image acquisition, compositing, and display |
| US7155049B2 (en) | 2001-01-11 | 2006-12-26 | Trestle Acquisition Corp. | System for creating microscopic digital montage images |
| EP1349493A2 (en) | 2001-01-12 | 2003-10-08 | The General Hospital Corporation | System and method for enabling simultaneous calibration and imaging of a medium |
| EP1366289B1 (en) | 2001-01-30 | 2007-04-11 | Outland Technologies, Inc. | Minimal contact seal positive displacement device, method and apparatus |
| JP4937457B2 (ja) | 2001-03-01 | 2012-05-23 | オリンパス株式会社 | 顕微鏡制御装置、顕微鏡制御システム、顕微鏡の制御方法、プログラム、及び記録媒体 |
| US6898451B2 (en) | 2001-03-21 | 2005-05-24 | Minformed, L.L.C. | Non-invasive blood analyte measuring system and method utilizing optical absorption |
| US6519355B2 (en) | 2001-03-28 | 2003-02-11 | Alan C. Nelson | Optical projection imaging system and method for automatically detecting cells having nuclear and cytoplasmic densitometric features associated with disease |
| US20040131348A1 (en) | 2001-03-30 | 2004-07-08 | Kohtaro Ohba | Real-time omnifocus microscope camera |
| US7151246B2 (en) | 2001-07-06 | 2006-12-19 | Palantyr Research, Llc | Imaging system and methodology |
| US7385168B2 (en) | 2001-07-06 | 2008-06-10 | Palantyr Research, Llc | Imaging system, methodology, and applications employing reciprocal space optical design |
| US7439478B2 (en) | 2001-07-06 | 2008-10-21 | Palantyr Research, Llc | Imaging system, methodology, and applications employing reciprocal space optical design having at least one pixel being scaled to about a size of a diffraction-limited spot defined by a microscopic optical system |
| US6664528B1 (en) | 2001-07-06 | 2003-12-16 | Palantyr Research, Llc | Imaging system and methodology employing reciprocal space optical design |
| US7132636B1 (en) | 2001-07-06 | 2006-11-07 | Palantyr Research, Llc | Imaging system and methodology employing reciprocal space optical design |
| US7105795B2 (en) | 2001-07-06 | 2006-09-12 | Palantyr Research, Llc | Imaging system, methodology, and applications employing reciprocal space optical design |
| US6872930B2 (en) | 2003-03-31 | 2005-03-29 | Palantyr Research, Llc | Imaging system and methodology employing reciprocal space optical design |
| US7338168B2 (en) | 2001-07-06 | 2008-03-04 | Palantyr Research, Llc | Particle analyzing system and methodology |
| US7248716B2 (en) | 2001-07-06 | 2007-07-24 | Palantyr Research, Llc | Imaging system, methodology, and applications employing reciprocal space optical design |
| US7288751B2 (en) | 2001-07-06 | 2007-10-30 | Palantyr Research, Llc | Imaging system, methodology, and applications employing reciprocal space optical design |
| US6884983B2 (en) | 2002-06-10 | 2005-04-26 | Palantyr Research, Llc | Imaging system for examining biological material |
| US7863552B2 (en) | 2001-07-06 | 2011-01-04 | Palantyr Research Llc | Digital images and related methodologies |
| JP4751535B2 (ja) | 2001-07-26 | 2011-08-17 | シスメックス株式会社 | 分画方法とそれを用いた血液分析装置 |
| CA2459320C (en) | 2001-09-06 | 2016-07-05 | Genomic Profiling Systems, Inc. | Rapid detection of replicating cells |
| US6989891B2 (en) | 2001-11-08 | 2006-01-24 | Optiscan Biomedical Corporation | Device and method for in vitro determination of analyte concentrations within body fluids |
| SE0104443D0 (sv) | 2001-12-28 | 2001-12-28 | Hemocue Ab | Analysis method and cuvette therefor |
| US7713474B2 (en) | 2002-01-15 | 2010-05-11 | Siemens Healthcare Diagnostics Inc. | Liquid permeable composition in dry reagent devices |
| US7133547B2 (en) | 2002-01-24 | 2006-11-07 | Tripath Imaging, Inc. | Method for quantitative video-microscopy and associated system and computer software program product |
| WO2003065358A2 (en) | 2002-01-28 | 2003-08-07 | Burstein Technologies, Inc. | Methods and apparatus for logical triggering of an optical bio-disc |
| AU2003217694A1 (en) | 2002-02-22 | 2003-09-09 | Bacus Research Laboratories, Inc. | Focusable virtual microscopy apparatus and method |
| US20030161514A1 (en) | 2002-02-28 | 2003-08-28 | Curry Bo U. | Bi-directional scanner control system |
| DE10246777A1 (de) | 2002-03-21 | 2003-10-02 | Endress & Hauser Wetzer Gmbh | Vorrichtung zur Identifizierung eines Probennehmerbehälters |
| DE10217404A1 (de) | 2002-04-18 | 2003-11-06 | Leica Microsystems | Autofokusverfahren für ein Mikroskop und System zum Einstellen des Fokus für ein Mikroskop |
| US6658143B2 (en) | 2002-04-29 | 2003-12-02 | Amersham Biosciences Corp. | Ray-based image analysis for biological specimens |
| WO2003093469A2 (en) | 2002-05-01 | 2003-11-13 | Chromos Molecular Systems, Inc. | Methods for delivering nucleic acid molecules into cells and assessment thereof |
| US7272252B2 (en) | 2002-06-12 | 2007-09-18 | Clarient, Inc. | Automated system for combining bright field and fluorescent microscopy |
| US20040122216A1 (en) | 2002-07-01 | 2004-06-24 | Jacob Nielsen | Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs |
| JP2004061942A (ja) | 2002-07-30 | 2004-02-26 | Nikon Corp | 顕微鏡システム |
| US7838296B2 (en) | 2002-08-28 | 2010-11-23 | Separation Technology, Inc. | Methods and apparatus for ultrasonic determination of red blood cell indices |
| US7177767B2 (en) | 2002-10-18 | 2007-02-13 | Abaxis, Inc. | Systems and methods for the detection of short and long samples |
| JP3904505B2 (ja) | 2002-10-22 | 2007-04-11 | 独立行政法人科学技術振興機構 | マラリア感染診断剤及びマラリア原虫染色剤 |
| DE10254685A1 (de) | 2002-11-22 | 2004-06-03 | Roche Diagnostics Gmbh | Messeinrichtung zur optischen Untersuchung eines Testelements |
| US7490085B2 (en) | 2002-12-18 | 2009-02-10 | Ge Medical Systems Global Technology Company, Llc | Computer-assisted data processing system and method incorporating automated learning |
| US20040132171A1 (en) | 2003-01-06 | 2004-07-08 | Peter Rule | Wearable device for measuring analyte concentration |
| US7596251B2 (en) | 2003-01-31 | 2009-09-29 | Nexus Biosystems, Inc. | Automated sample analysis system and method |
| JP3869810B2 (ja) | 2003-02-24 | 2007-01-17 | 株式会社堀場製作所 | マイクロ血球カウンタ |
| US6955872B2 (en) | 2003-03-20 | 2005-10-18 | Coulter International Corp. | Dye compositions which provide enhanced differential fluorescence and light scatter characteristics |
| CN1795272B (zh) | 2003-03-27 | 2013-04-24 | 巴特朗医疗成像有限责任公司 | 快速识别病原体、细菌和异常细胞的系统和方法 |
| GB2401431B (en) | 2003-04-02 | 2005-04-27 | Amersham Biosciences Uk Ltd | Method of, and computer software for, classification of cells into subpopulations |
| US7706862B2 (en) | 2003-04-17 | 2010-04-27 | Research Foundation Of The City University Of New York | Detecting human cancer through spectral optical imaging using key water absorption wavelengths |
| US7329537B2 (en) | 2003-04-17 | 2008-02-12 | Nexcelom Bioscience, Llc | Micro-pattern embedded plastic optical film device for cell-based assays |
| US7324694B2 (en) | 2003-05-23 | 2008-01-29 | International Remote Imaging Systems, Inc. | Fluid sample analysis using class weights |
| DE10324248A1 (de) | 2003-05-28 | 2005-01-05 | Bayerische Motoren Werke Ag | Kunststoffträger und Verfahren zu seiner Herstellung |
| US20040241677A1 (en) | 2003-05-29 | 2004-12-02 | Lin Jeffrey S | Techniques for automated diagnosis of cell-borne anomalies with digital optical microscope |
| WO2004111610A2 (en) | 2003-06-12 | 2004-12-23 | Accupath Diagnostic Laboratories, Inc. | Method and system for the analysis of high density cells samples |
| EP1649038B1 (en) | 2003-06-26 | 2014-07-02 | Litron Laboratories Ltd. | Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates |
| JP4773348B2 (ja) | 2003-07-12 | 2011-09-14 | アクセラー8 テクノロジー コーポレイション | 高感度かつ迅速なバイオ検出法 |
| KR100573621B1 (ko) | 2003-07-18 | 2006-04-25 | 주식회사 디지탈바이오테크놀러지 | 세포 개체수 계수용 장치 및 그 제조방법 |
| US7411680B2 (en) | 2003-07-19 | 2008-08-12 | Digital Bio Technology | Device for counting micro particles |
| SE0302114D0 (sv) | 2003-07-21 | 2003-07-21 | Cellavision Ab | Sätt att urskilja en objektkontur |
| US20050089208A1 (en) | 2003-07-22 | 2005-04-28 | Rui-Tao Dong | System and method for generating digital images of a microscope slide |
| WO2005017025A2 (en) | 2003-08-15 | 2005-02-24 | The President And Fellows Of Harvard College | Study of polymer molecules and conformations with a nanopore |
| US7998435B2 (en) | 2003-09-19 | 2011-08-16 | Life Technologies Corporation | High density plate filler |
| US20060233671A1 (en) | 2003-09-19 | 2006-10-19 | Beard Nigel P | High density plate filler |
| JP4521490B2 (ja) | 2003-11-21 | 2010-08-11 | 国立大学法人高知大学 | 類似パターン検索装置、類似パターン検索方法、類似パターン検索プログラム、および分画分離装置 |
| US7030351B2 (en) | 2003-11-24 | 2006-04-18 | Mitutoyo Corporation | Systems and methods for rapidly automatically focusing a machine vision inspection system |
| ES2332523T3 (es) | 2004-02-09 | 2010-02-08 | Rapid Pathogen Screening Inc. | Metodo para el diagnostico rapido de blancos en fluidos corporales humanos. |
| JP4804363B2 (ja) | 2004-02-09 | 2011-11-02 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 蛍光顕微鏡装置 |
| US9176121B2 (en) | 2004-02-13 | 2015-11-03 | Roche Diagnostics Hematology, Inc. | Identification of blood elements using inverted microscopy |
| JP4417143B2 (ja) | 2004-03-11 | 2010-02-17 | シスメックス株式会社 | 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体 |
| CA2559171A1 (en) | 2004-03-12 | 2005-09-29 | Biotrove, Inc. | Nanoliter array loading |
| US7925070B2 (en) | 2004-03-30 | 2011-04-12 | Sysmex Corporation | Method for displaying virtual slide and terminal device for displaying virtual slide |
| US20060051778A1 (en) | 2004-03-31 | 2006-03-09 | Kallick Charles A | Diagnosis of systemic lupus erythematosus |
| EP1733226B1 (en) | 2004-04-07 | 2015-07-29 | Levine, Robert Aaron | Disposable chamber for analyzing biologic fluids |
| RU2006144458A (ru) | 2004-05-14 | 2008-06-20 | БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) | Способы осуществления корректировки по гематокриту в анализах глюкозы и устройства для этого |
| EP1787156A1 (en) | 2004-06-11 | 2007-05-23 | Nicholas Etienne Ross | Automated diagnosis of malaria and other infections |
| DE602005023305D1 (de) | 2004-06-17 | 2010-10-14 | Koninkl Philips Electronics Nv | Autofocus-mechanismus für ein spektroskopisches system |
| GB0414201D0 (en) | 2004-06-24 | 2004-07-28 | Fujifilm Electronic Imaging | Method and apparatus for forming a multiple focus stack image |
| US20060002817A1 (en) | 2004-06-30 | 2006-01-05 | Sebastian Bohm | Flow modulation devices |
| US8582924B2 (en) | 2004-06-30 | 2013-11-12 | Carl Zeiss Microimaging Gmbh | Data structure of an image storage and retrieval system |
| US7456377B2 (en) | 2004-08-31 | 2008-11-25 | Carl Zeiss Microimaging Ais, Inc. | System and method for creating magnified images of a microscope slide |
| US20060063185A1 (en) | 2004-09-09 | 2006-03-23 | Edouard Vannier | Methods for detection of pathogens in red blood cells |
| US20060095241A1 (en) | 2004-10-29 | 2006-05-04 | Microsoft Corporation | Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails |
| EP1802959A1 (en) | 2004-10-11 | 2007-07-04 | Thermo Fisher Scientific Oy | Method for automatically detecting factors that disturb analysis by a photometer |
| US8045782B2 (en) | 2004-12-07 | 2011-10-25 | Ge Healthcare Niagara, Inc. | Method of, and apparatus and computer software for, implementing image analysis protocols |
| CN101088003A (zh) | 2004-12-13 | 2007-12-12 | 拜尔保健有限公司 | 用于确定体液中被分析物的透射光谱学系统 |
| CN102879525B (zh) | 2004-12-13 | 2014-12-24 | 拜尔保健有限公司 | 独立式测试传感器 |
| JP2008523407A (ja) | 2004-12-14 | 2008-07-03 | ユニバーシティ・オブ・ジ・ウィトウォーターズランド・ヨハネスブルク | 疾患の細胞貯蔵庫を診断しモニターする方法 |
| US20060200070A1 (en) | 2005-02-14 | 2006-09-07 | Callicoat David N | Method and apparatus for calibrating an analyte detection system with a calibration sample |
| RU2289133C1 (ru) * | 2005-03-03 | 2006-12-10 | Виктор Александрович Клемин | Способ определения гемоглобина, количества эритроцитов, лейкоцитов, тромбоцитов, гематокрита и скорости оседания эритроцитов в цельной крови |
| US20060223052A1 (en) | 2005-03-30 | 2006-10-05 | Kimberly-Clark Worldwide, Inc. | Technique for detecting microorganisms |
| EP1866637B1 (en) | 2005-04-01 | 2016-02-03 | pts Diagnostics | Body fluid testing component for analyte detection |
| US7580120B2 (en) | 2005-04-07 | 2009-08-25 | Sysmex Corporation | Blood analyzer, sample analyzer, and flow cytometer |
| JP2006301270A (ja) | 2005-04-20 | 2006-11-02 | Hitachi Kokusai Electric Inc | オートフォーカス装置及びオートフォーカス方法 |
| JP4667944B2 (ja) | 2005-04-20 | 2011-04-13 | シスメックス株式会社 | 画像作成装置 |
| FR2884920B1 (fr) | 2005-04-21 | 2007-08-10 | Horiba Abx Sa Sa | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
| US7688427B2 (en) * | 2005-04-29 | 2010-03-30 | Honeywell International Inc. | Particle parameter determination system |
| EP1888778B1 (en) | 2005-05-06 | 2012-11-14 | Samsung Electronics Co., Ltd. | Digital bio disc(dbd), dbd driver apparatus, and assay method using the same |
| AT501944B1 (de) | 2005-06-15 | 2007-06-15 | Tissuegnostics Gmbh | Verfahren zum segmentieren von leukozyten |
| US7417213B2 (en) | 2005-06-22 | 2008-08-26 | Tripath Imaging, Inc. | Apparatus and method for rapid microscopic image focusing having a movable objective |
| US7532314B1 (en) | 2005-07-14 | 2009-05-12 | Battelle Memorial Institute | Systems and methods for biological and chemical detection |
| US20070031056A1 (en) | 2005-08-02 | 2007-02-08 | Perz Cynthia B | System for and method of focusing in automated microscope systems |
| JP2007040814A (ja) | 2005-08-03 | 2007-02-15 | Matsushita Electric Ind Co Ltd | 吸光度測定用センサ及び吸光度測定方法 |
| US7776553B2 (en) | 2005-09-16 | 2010-08-17 | Presidents And Fellows Of Harvard College | Screening assays and methods |
| US7609369B2 (en) | 2005-09-24 | 2009-10-27 | Beckman Coulter, Inc. | Methods of detection of iron deficiency and hemochromatosis |
| US7796797B2 (en) | 2005-09-28 | 2010-09-14 | Sysmex Corporation | Apparatus for obtaining an image of a blood cell and method for obtaining an image of a blood cell |
| US7599893B2 (en) | 2005-10-13 | 2009-10-06 | Aureon Laboratories, Inc. | Methods and systems for feature selection in machine learning based on feature contribution and model fitness |
| GB2431537B (en) | 2005-10-20 | 2011-05-04 | Amersham Biosciences Uk Ltd | Method of processing an image |
| US7344890B2 (en) | 2005-11-09 | 2008-03-18 | Beckman Coulter, Inc. | Method for discriminating platelets from red blood cells |
| US7933435B2 (en) | 2005-11-21 | 2011-04-26 | Vala Sciences, Inc. | System, method, and kit for processing a magnified image of biological material to identify components of a biological object |
| WO2007063131A1 (en) | 2005-12-01 | 2007-06-07 | Evotec Technologies Gmbh | A generic assay for monitoring endocytosis |
| US7361512B2 (en) * | 2006-01-20 | 2008-04-22 | Beckman Coulter, Inc. | Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency |
| SE529536C2 (sv) | 2006-01-25 | 2007-09-04 | Hemocue Ab | Metod för säkerställande av en provbehållares kvalitet |
| GB2435925A (en) | 2006-03-09 | 2007-09-12 | Cytokinetics Inc | Cellular predictive models for toxicities |
| SE530244C2 (sv) | 2006-05-05 | 2008-04-08 | Hemocue Ab | Förfarande och system för kvantitativ hemoglobinbestämning |
| EP2023127B1 (en) | 2006-05-31 | 2017-12-20 | Olympus Corporation | Biological specimen imaging method and biological specimen imaging apparatus |
| CN101501785A (zh) | 2006-06-02 | 2009-08-05 | 维克托·B·克利 | 针对米到亚纳米长度范围内的高速测量、分析和成像的系统及方法 |
| JP5040191B2 (ja) | 2006-06-29 | 2012-10-03 | 富士通株式会社 | マイクロインジェクション装置及び自動焦点調整方法 |
| AT503862B1 (de) | 2006-07-05 | 2010-11-15 | Arc Austrian Res Centers Gmbh | Pathogen-identifizierung anhand eines 16s oder 18s-rrna mikroarray |
| DE102006031177A1 (de) | 2006-07-06 | 2008-01-10 | Carl Zeiss Microimaging Gmbh | Verfahren und Vorrichtung zur Erzeugung eines Bildes einer dünnen Schicht eines Objekts |
| SE530750C2 (sv) | 2006-07-19 | 2008-09-02 | Hemocue Ab | En mätapparat, en metod och ett datorprogram |
| US8067245B2 (en) | 2006-07-24 | 2011-11-29 | Medica Corporation | Automated microscope for blood cell analysis |
| US7542137B2 (en) | 2006-07-24 | 2009-06-02 | University Of Ottawa | Pathogen detection using coherent anti-stokes Raman scattering microscopy |
| US8428331B2 (en) | 2006-08-07 | 2013-04-23 | Northeastern University | Phase subtraction cell counting method |
| WO2008033393A2 (en) | 2006-09-11 | 2008-03-20 | University Of Florida | Isolation, expansion and uses of tumor stem cells |
| WO2008063135A1 (en) | 2006-11-24 | 2008-05-29 | Agency For Science, Technology And Research | Apparatus for processing a sample in a liquid droplet and method of using the same |
| KR100844350B1 (ko) | 2007-01-09 | 2008-07-07 | 주식회사 디지탈바이오테크놀러지 | 부유 혼합 미세입자 중 특정 미세입자를 광학적인 방법으로계수하기 위한 미세채널 칩 및 이를 이용한 미세입자 계수방법 |
| US8526704B2 (en) | 2007-01-11 | 2013-09-03 | Intellectual Property Mvm B.V. | Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis |
| US7738094B2 (en) | 2007-01-26 | 2010-06-15 | Becton, Dickinson And Company | Method, system, and compositions for cell counting and analysis |
| US8877458B2 (en) | 2007-02-02 | 2014-11-04 | Canadian Blood Services | Method of detecting bacterial contamination using dynamic light scattering |
| US8131035B2 (en) | 2007-02-05 | 2012-03-06 | Siemens Healthcare Diagnostics Inc. | Cell analysis using isoperimetric graph partitioning |
| GB0704035D0 (en) | 2007-03-02 | 2007-04-11 | Smiths Detection Watford Ltd | Sample preparation apparatus |
| JP5105945B2 (ja) | 2007-04-19 | 2012-12-26 | キヤノン株式会社 | 雲台装置及びその制御方法 |
| DE102007021387A1 (de) | 2007-05-04 | 2008-11-06 | Eads Deutschland Gmbh | Detektionsvorrichtung zur Detektion von biologischen Mikropartikeln wie Bakterien, Viren, Sporen, Pollen oder biologische Toxine, sowie Detektionsverfahren |
| US20080305514A1 (en) | 2007-06-06 | 2008-12-11 | Alcon Research, Ltd. | Method for detecting microbes |
| KR100900511B1 (ko) | 2007-07-23 | 2009-06-03 | 주식회사 디지탈바이오테크놀러지 | 유체분석용 칩 |
| EP2171420A1 (en) | 2007-07-31 | 2010-04-07 | Micronics, Inc. | Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays |
| CA2604317C (en) | 2007-08-06 | 2017-02-28 | Historx, Inc. | Methods and system for validating sample images for quantitative immunoassays |
| US7936913B2 (en) | 2007-08-07 | 2011-05-03 | Nextslide Imaging Llc | Network image review in clinical hematology |
| US8878923B2 (en) | 2007-08-23 | 2014-11-04 | General Electric Company | System and method for enhanced predictive autofocusing |
| CN101387599B (zh) | 2007-09-13 | 2011-01-26 | 深圳迈瑞生物医疗电子股份有限公司 | 一种区分粒子群落的方法及粒子分析仪 |
| US8331627B2 (en) | 2007-09-26 | 2012-12-11 | Agency For Science, Technology And Research | Method and system for generating an entirely well-focused image of a large three-dimensional scene |
| US8088593B2 (en) | 2007-10-02 | 2012-01-03 | Theranos, Inc. | Modular point-of-care devices, systems, and uses thereof |
| JP2009109198A (ja) | 2007-10-26 | 2009-05-21 | Arkray Inc | 分析装置 |
| KR101009447B1 (ko) | 2007-11-12 | 2011-01-19 | 바디텍메드 주식회사 | 체액 샘플링, 전처리 및 투입장치 및 방법 |
| US8125512B2 (en) | 2007-11-16 | 2012-02-28 | Samsung Electronics Co., Ltd. | System and method for moving object selection in a handheld image capture device |
| WO2009088930A2 (en) | 2008-01-02 | 2009-07-16 | The Regents Of The University Of California | High numerical aperture telemicroscopy apparatus |
| US20090185734A1 (en) | 2008-01-18 | 2009-07-23 | Hemocue Ab | Apparatus and method for analysis of particles in a liquid sample |
| JP4558047B2 (ja) | 2008-01-23 | 2010-10-06 | オリンパス株式会社 | 顕微鏡システム、画像生成方法、及びプログラム |
| JP5365011B2 (ja) | 2008-01-29 | 2013-12-11 | 日本電気株式会社 | 病理診断支援装置、病理診断支援方法、およびプログラム |
| US20110007178A1 (en) | 2008-03-12 | 2011-01-13 | Koninklijke Philips Electronics N.V. | Correction of spot area in measuring brightness of sample in biosensing device |
| ES2588223T3 (es) | 2008-03-21 | 2016-10-31 | Abbott Point Of Care, Inc. | Procedimiento para el análisis de células individuales o partículas en la sangre usando fluorescencia y absorción de un colorante |
| EP2271937B1 (en) | 2008-03-21 | 2016-01-13 | Abbott Point Of Care, Inc. | Method and apparatus for detecting and counting platelets individually and in aggregate clumps |
| US7951599B2 (en) | 2008-03-21 | 2011-05-31 | Abbott Point Of Care, Inc. | Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells |
| CN102027368B (zh) * | 2008-03-21 | 2014-02-26 | 艾博特健康公司 | 利用红细胞内含有的血红蛋白的本征色素沉着来确定血样的红细胞指数的方法及设备 |
| JP2009233927A (ja) | 2008-03-26 | 2009-10-15 | Toshiba Tec Corp | インクジェットヘッドの製造方法 |
| EP2257819A4 (en) | 2008-03-27 | 2017-10-11 | President and Fellows of Harvard College | Three-dimensional microfluidic devices |
| US8883491B2 (en) | 2008-04-09 | 2014-11-11 | Nexcelom Bioscience Llc | Systems and methods for counting cells and biomolecules |
| JP2012515931A (ja) | 2008-04-25 | 2012-07-12 | ウィンケルマン、ジェイムズ | 全血球数及び白血球百分率を決定するシステム及び方法 |
| US8379944B2 (en) | 2008-04-29 | 2013-02-19 | Siemens Healthcare Diagnostics Inc. | Identification, classification and counting of targets of interest in multispectral image data |
| JP2009268432A (ja) | 2008-05-09 | 2009-11-19 | Canon Inc | 標的核酸の測定方法 |
| CN102016577B (zh) * | 2008-05-09 | 2015-06-17 | 希森美康株式会社 | 血液分析装置,血液分析方法及溶血剂 |
| WO2009140757A1 (en) | 2008-05-20 | 2009-11-26 | University Health Network | Device and method for fluorescence-based imaging and monitoring |
| CN102076841B (zh) | 2008-06-27 | 2015-04-22 | 古河电气工业株式会社 | 细胞的识别和分选方法及其装置 |
| DE102008030874A1 (de) | 2008-06-30 | 2010-01-07 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zum Ermitteln einer Kontur und eines Mittelpunktes eines Objekts |
| US8491840B2 (en) | 2008-07-14 | 2013-07-23 | Samsung Electronics Co., Ltd. | Microfluidic device, sample analyzing method using the same, and dilution ratio measuring method |
| US8385971B2 (en) | 2008-08-19 | 2013-02-26 | Digimarc Corporation | Methods and systems for content processing |
| JP5492207B2 (ja) | 2008-08-27 | 2014-05-14 | ライフ テクノロジーズ コーポレーション | 生物学的サンプルの処理装置および処理方法 |
| WO2010033508A1 (en) | 2008-09-16 | 2010-03-25 | Historx, Inc. | Reproducible quantification of biomarker expression |
| US8280134B2 (en) | 2008-09-22 | 2012-10-02 | Cambridge Research & Instrumentation, Inc. | Multi-spectral imaging including at least one common stain |
| AU2009296526B2 (en) | 2008-09-24 | 2015-11-19 | First Light Diagnostics, Inc. | Method for detecting analytes |
| JP5380973B2 (ja) | 2008-09-25 | 2014-01-08 | 株式会社ニコン | 画像処理装置及び画像処理プログラム |
| JP5288970B2 (ja) * | 2008-09-26 | 2013-09-11 | シスメックス株式会社 | 血液試料希釈用試薬を用いた平均赤血球容積の測定方法 |
| EP2353042A4 (en) | 2008-10-14 | 2013-06-26 | Sanford Burnham Med Res Inst | AUTOMATED SCANNING CYTOMETRY WITH CHROMATIC ABERRATION FOR MULTIPLANAR IMAGE RECORDING |
| US8842900B2 (en) | 2008-10-28 | 2014-09-23 | Sysmex Corporation | Specimen processing system and blood cell image classifying apparatus |
| CN102282467B (zh) * | 2008-11-13 | 2014-08-13 | 贝克曼考尔特公司 | 对血红蛋白测量的颗粒干扰的校正的方法 |
| CN101403650B (zh) | 2008-11-21 | 2010-06-23 | 北京理工大学 | 差动共焦组合超长焦距测量方法与装置 |
| WO2010061319A1 (en) | 2008-11-27 | 2010-06-03 | Koninklijke Philips Electronics N.V. | Generation of a multicolour image of an unstained biological specimen |
| US20100157086A1 (en) | 2008-12-15 | 2010-06-24 | Illumina, Inc | Dynamic autofocus method and system for assay imager |
| GB0900526D0 (en) | 2009-01-14 | 2009-02-11 | Perkinelmer Ltd | Fluorescence microscopy methods and apparatus |
| JP5426181B2 (ja) | 2009-01-21 | 2014-02-26 | シスメックス株式会社 | 検体処理システム、細胞画像分類装置、及び検体処理方法 |
| EP2216095A1 (en) | 2009-01-27 | 2010-08-11 | Koninklijke Philips Electronics N.V. | Microfluidic device for full blood count |
| JP2011095225A (ja) | 2009-11-02 | 2011-05-12 | Olympus Corp | 画像処理装置、画像処理方法および顕微鏡システム |
| US9778188B2 (en) | 2009-03-11 | 2017-10-03 | Industrial Technology Research Institute | Apparatus and method for detection and discrimination molecular object |
| BRPI1014853A2 (pt) | 2009-04-01 | 2015-08-25 | Tearscience Inc | Dispositivos, sistemas e métodos de interferometria de superfície ocular (osi) para formação de imagem, processamento e/ou visualização de um filme lacrimal ocular e/ou medição de espessura(s) de camada de filme lacrimal ocular |
| BRPI1006723A2 (pt) | 2009-04-09 | 2017-10-10 | Koninl Philips Electronics Nv | equipamento para produzir camadas de um fluido, método para preparar camadas de um fluido que contém células, método de equipamento de fabricação para produzir camadas de um fluido que contém células, sistema de análise e método para analisar camadas de um fluido que contém células |
| AU2010241731B2 (en) | 2009-04-27 | 2015-08-06 | Roche Diagnostics Hematology, Inc. | Systems and methods for analyzing body fluids |
| JP5424712B2 (ja) | 2009-05-21 | 2014-02-26 | キヤノン株式会社 | 画像処理装置及びその制御方法とプログラム |
| WO2010137543A1 (ja) | 2009-05-27 | 2010-12-02 | 株式会社日立ハイテクノロジーズ | 核酸分析用デバイス、核酸分析装置、及び核酸分析方法 |
| US20100300563A1 (en) | 2009-05-27 | 2010-12-02 | John Ramunas | Modular device and method for moving fluids to and from a sample delivery element |
| US8891851B2 (en) | 2009-07-15 | 2014-11-18 | Glenn F. Spaulding | Home healthcare management system and hardware |
| US8481303B2 (en) | 2009-10-12 | 2013-07-09 | Corning Incorporated | Microfluidic device for cell culture |
| US8320655B2 (en) | 2009-10-16 | 2012-11-27 | General Electric Company | Process and system for analyzing the expression of biomarkers in cells |
| KR101424414B1 (ko) | 2009-10-19 | 2014-08-01 | 벤타나 메디컬 시스템즈, 인코포레이티드 | 현미경 스테이지에 대한 디바이스 |
| WO2011056658A1 (en) | 2009-10-27 | 2011-05-12 | Duke University | Multi-photon microscopy via air interface objective lens |
| JP5394887B2 (ja) | 2009-10-29 | 2014-01-22 | オリンパス株式会社 | 顕微鏡装置および顕微鏡観察方法 |
| CN102053051A (zh) | 2009-10-30 | 2011-05-11 | 西门子公司 | 一种体液分析系统和用于体液分析的图像处理设备、方法 |
| US20120058504A1 (en) | 2009-10-30 | 2012-03-08 | Simon Fraser University | Methods and apparatus for dielectrophoretic shuttling and measurement of single cells or other particles in microfluidic chips |
| US9072772B2 (en) | 2009-11-05 | 2015-07-07 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods of treating disorders associated with protein aggregation |
| US9119573B2 (en) | 2009-12-10 | 2015-09-01 | Siemens Aktiengesellschaft | Stent marker detection using a learning based classifier in medical imaging |
| WO2011076413A1 (en) | 2009-12-22 | 2011-06-30 | Universität Heidelberg | Means and methods for detecting plasmodia and for screening or diagnosing drug resistance or altered drug responsiveness of plasmodia |
| US8748186B2 (en) * | 2009-12-22 | 2014-06-10 | Abbott Laboratories | Method for performing a blood count and determining the morphology of a blood smear |
| US8237786B2 (en) | 2009-12-23 | 2012-08-07 | Applied Precision, Inc. | System and method for dense-stochastic-sampling imaging |
| EP2519820B1 (en) | 2009-12-31 | 2013-11-06 | Abbott Point Of Care, Inc. | Method and apparatus for determining mean cell volume of red blood cells |
| US8906308B2 (en) * | 2010-01-15 | 2014-12-09 | Abbott Laboratories | Method for determining volume and hemoglobin content of individual red blood cells |
| CN102822657B (zh) | 2010-01-20 | 2016-01-20 | 耐克思乐生物科学有限责任公司 | 细胞计数和样品室及其装配方法 |
| US9132423B2 (en) | 2010-01-29 | 2015-09-15 | Micronics, Inc. | Sample-to-answer microfluidic cartridge |
| JP5490568B2 (ja) | 2010-02-26 | 2014-05-14 | オリンパス株式会社 | 顕微鏡システム、標本観察方法およびプログラム |
| SG174650A1 (en) | 2010-03-31 | 2011-10-28 | Agency Science Tech & Res | A method of monitoring parasite development in blood |
| US9199233B2 (en) | 2010-03-31 | 2015-12-01 | Abbott Point Of Care, Inc. | Biologic fluid analysis cartridge with deflecting top panel |
| US8396269B2 (en) | 2010-04-08 | 2013-03-12 | Digital Pathco LLC | Image quality assessment including comparison of overlapped margins |
| US8040517B1 (en) | 2010-04-30 | 2011-10-18 | General Electric Company | Arc flash detection system and method |
| US9442106B2 (en) | 2010-05-08 | 2016-09-13 | Universiteit Twente | Simple and affordable method for immunophenotyping using a microfluidic chip sample preparation with image cytometry |
| JP5864559B2 (ja) | 2010-06-04 | 2016-02-17 | ライカ バイオシステムズ イメージング インコーポレイテッドAperio Technologies, Inc. | デジタル化された顕微鏡スライドのスライド品質を判断するシステム及び方法 |
| WO2011156068A1 (en) | 2010-06-07 | 2011-12-15 | Caridianbct, Inc. | Multi-unit blood processor with volume prediction |
| WO2012000102A1 (en) | 2010-06-30 | 2012-01-05 | The Governors Of The University Of Alberta | Apparatus and method for microscope-based label-free microflutdic cytometry |
| WO2012006565A2 (en) | 2010-07-08 | 2012-01-12 | Life Technologies Corporation | Systems and methods for assigning attributes to a plurality of samples |
| US20150032671A9 (en) | 2010-07-23 | 2015-01-29 | General Electric Company | Systems and methods for selecting and analyzing particles in a biological tissue |
| US10139613B2 (en) | 2010-08-20 | 2018-11-27 | Sakura Finetek U.S.A., Inc. | Digital microscope and method of sensing an image of a tissue sample |
| CN103168242B (zh) | 2010-09-02 | 2016-02-03 | 国立大学法人东北大学 | 癌症发病或癌症发病风险的判定方法 |
| US8933927B2 (en) | 2010-09-02 | 2015-01-13 | Samsung Electronics Co., Ltd. | Display system with image conversion mechanism and method of operation thereof |
| EP2616990A1 (en) | 2010-09-16 | 2013-07-24 | University Of Kansas | System and methods for digital evaluation of cellblock preparations |
| US8351676B2 (en) | 2010-10-12 | 2013-01-08 | Sony Corporation | Digital image analysis using multi-step analysis |
| US8542274B2 (en) | 2010-10-18 | 2013-09-24 | Olympus America Inc. | Wide field microscopic imaging system and method |
| USD655421S1 (en) | 2010-11-03 | 2012-03-06 | Life Technologies Corporation | Cell counter |
| US9050595B2 (en) | 2010-12-03 | 2015-06-09 | Abbott Point Of Care Inc. | Assay devices with integrated sample dilution and dilution verification and methods of using same |
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| JP5331828B2 (ja) | 2011-01-14 | 2013-10-30 | 株式会社日立ハイテクノロジーズ | 荷電粒子線装置 |
| EP2676173B1 (en) * | 2011-02-16 | 2023-03-29 | Phase Holographic Imaging Phi AB | Determination of physical parameters associated with erythrocytes |
| AU2012228063A1 (en) | 2011-03-14 | 2013-10-24 | The University Of Warwick | Histology analysis |
| EP2694932B1 (en) | 2011-04-07 | 2018-02-21 | The UWM Research Foundation, Inc | High speed microscope with spectral resolution |
| US9064301B2 (en) | 2011-04-14 | 2015-06-23 | Abbott Point Of Care, Inc. | Method and apparatus for compressing imaging data of whole blood sample analyses |
| JP5997256B2 (ja) | 2011-04-15 | 2016-09-28 | コンスティテューション・メディカル・インコーポレイテッドConstitution Medical, Inc. | 細胞の体積および成分の計測 |
| EP2720728A4 (en) | 2011-06-14 | 2014-12-10 | Hangzhou Everlong Biotechnics Co Ltd | TARGETED, MAGNETICALLY EXPANDED PATIENT DETECTION SYSTEM |
| TWI493505B (zh) | 2011-06-20 | 2015-07-21 | 晨星半導體股份有限公司 | 影像處理方法以及影像處理裝置 |
| US8792693B2 (en) | 2011-07-09 | 2014-07-29 | Gauss Surgical | System and method for estimating extracorporeal blood volume in a physical sample |
| US10426356B2 (en) | 2011-07-09 | 2019-10-01 | Gauss Surgical, Inc. | Method for estimating a quantity of a blood component in a fluid receiver and corresponding error |
| US9684281B2 (en) | 2011-07-19 | 2017-06-20 | Ovizio Imaging Systems NV/SA | Method and system for detecting and/or classifying cancerous cells in a cell sample |
| CN103827658B (zh) | 2011-07-22 | 2016-04-13 | 罗氏血液诊断股份有限公司 | 识别和测量网状细胞 |
| JP5959814B2 (ja) | 2011-08-08 | 2016-08-02 | ソニー株式会社 | 血液分析装置および血液分析方法 |
| WO2013037119A1 (zh) | 2011-09-16 | 2013-03-21 | 长沙高新技术产业开发区爱威科技实业有限公司 | 红细胞形态学分析装置及其方法 |
| WO2013041951A1 (en) | 2011-09-22 | 2013-03-28 | Foce Technology International Bv | Optical platelet counter method |
| US9046473B2 (en) | 2011-09-28 | 2015-06-02 | Abbott Point Of Care, Inc. | Method and apparatus for detecting the presence of intraerythrocytic parasites |
| US9526431B2 (en) | 2011-10-19 | 2016-12-27 | Biovotion Ag | System for noninvasive optical measurements of physiological properties in tissue |
| TWI431264B (zh) | 2011-10-20 | 2014-03-21 | Lite On It Corp | 光學偵測裝置及光學量測系統 |
| US8885912B2 (en) | 2011-11-03 | 2014-11-11 | General Electric Company | Generate percentage of positive cells for biomarkers by normalizing and autothresholding the image intensity produced by immunohistochemistry technique |
| US9028778B2 (en) | 2011-12-28 | 2015-05-12 | Abbott Laboratories | Accelerated Wright-Giemsa and May-Grünwald staining methods |
| WO2013098821A1 (en) | 2011-12-29 | 2013-07-04 | Parasight Ltd. | Methods and systems for detecting a pathogen in a biological sample |
| CN107064079A (zh) | 2011-12-30 | 2017-08-18 | 艾博特健康公司 | 用于识别全血样品中的血小板的方法和设备 |
| US20130169948A1 (en) | 2011-12-30 | 2013-07-04 | Abbott Point Of Care, Inc. | Method for rapid imaging of biologic fluid samples |
| US9322767B2 (en) | 2012-04-17 | 2016-04-26 | i-calQ, LLC | Device for performing a blood, cell, and/or pathogen count and methods for use thereof |
| WO2013170048A1 (en) | 2012-05-09 | 2013-11-14 | Advanced Animal Diagnostics, Inc. | Rapid detection of analytes in liquid samples |
| FR2991457B1 (fr) | 2012-06-01 | 2014-07-18 | Commissariat Energie Atomique | Procede et systeme de caracterisation de la vitesse de deplacement de particules contenues dans un liquide, telles que des particules sanguines |
| US8873827B2 (en) | 2012-06-29 | 2014-10-28 | General Electric Company | Determination of spatial proximity between features of interest in biological tissue |
| US8992750B1 (en) | 2012-07-02 | 2015-03-31 | Roche Diagnostics Operations, Inc. | Biosensor and methods for manufacturing |
| US8831733B2 (en) | 2012-07-16 | 2014-09-09 | California Institute Of Technology | Brain repair using electrical stimulation of healthy nodes |
| US8744165B2 (en) | 2012-07-19 | 2014-06-03 | Sony Corporation | Method and apparatus for stain separation in digital pathology images |
| JP5333635B1 (ja) | 2012-08-23 | 2013-11-06 | 富士ゼロックス株式会社 | 画像処理装置、プログラム及び画像処理システム |
| JP5464244B2 (ja) | 2012-08-24 | 2014-04-09 | 富士ゼロックス株式会社 | 画像処理装置、プログラム及び画像処理システム |
| EP2731051A1 (en) | 2012-11-07 | 2014-05-14 | bioMérieux | Bio-imaging method |
| US9400414B2 (en) | 2012-11-19 | 2016-07-26 | Raytheon Company | Methods and apparatus for imaging without retro-reflection using a tilted image plane and structured relay optic |
| DK2927311T3 (da) | 2012-11-28 | 2020-01-13 | Japan Science & Tech Agency | Celleovervågningsindretning, celleovervågningsfremgangsmåde og program dertil |
| WO2014089468A1 (en) | 2012-12-06 | 2014-06-12 | Abbott Point Of Care, Inc. | Imaging biologic fluids using a predetermined distribution |
| US10502666B2 (en) * | 2013-02-06 | 2019-12-10 | Alentic Microscience Inc. | Sample processing improvements for quantitative microscopy |
| WO2014159692A1 (en) | 2013-03-13 | 2014-10-02 | Tahoe Institute for Rural Health Research, LLC | Portable blood count monitor |
| WO2014159620A1 (en) | 2013-03-14 | 2014-10-02 | Samuels Mark A | Encoded calibration device and systems and methods thereof |
| WO2014141034A2 (en) | 2013-03-15 | 2014-09-18 | Richard Harry Turner | A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids |
| WO2014145983A1 (en) | 2013-03-15 | 2014-09-18 | Iris International, Inc. | Sheath fluid systems and methods for particle analysis in blood samples |
| US9064304B2 (en) | 2013-03-18 | 2015-06-23 | General Electric Company | Image quality assessment of microscopy images |
| WO2014188405A1 (en) | 2013-05-23 | 2014-11-27 | Parasight Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
| DE102013216362A1 (de) | 2013-08-19 | 2015-02-19 | Siemens Healthcare Diagnostics Products Gmbh | Analyseverfahren zur Klassifikationsunterstützung |
| CN103472216A (zh) * | 2013-08-23 | 2013-12-25 | 深圳中科强华科技有限公司 | 一种血细胞分析芯片、分析仪及分析方法 |
| EP3039477B1 (en) | 2013-08-26 | 2021-10-20 | S.D. Sight Diagnostics Ltd. | Digital microscopy systems, methods and computer program products |
| GB201318084D0 (en) | 2013-10-11 | 2013-11-27 | Isis Innovation | Malaria vaccination |
| CA3158669A1 (en) | 2013-12-17 | 2015-06-25 | Alentic Microscience Inc. | Dosimeters including lensless imaging systems |
| JP6194791B2 (ja) | 2013-12-27 | 2017-09-13 | 富士ゼロックス株式会社 | 画像処理装置及びプログラム |
| EP3155592B1 (en) | 2014-06-10 | 2019-09-11 | Leland Stanford Junior University | Predicting breast cancer recurrence directly from image features computed from digitized immunohistopathology tissue slides |
| US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| JP6352750B2 (ja) | 2014-09-26 | 2018-07-04 | シスメックス株式会社 | 血液分析装置および血液分析方法 |
| CA2962861A1 (en) | 2014-09-29 | 2016-04-07 | Chipcare Corporation | Methods and devices for cell detection |
| FR3028318B1 (fr) | 2014-11-12 | 2025-10-03 | Phuong Lan Tran | Procede et dispositif de tri selectif, specifique et simultane de cellules rares cibles dans un echantillon biologique |
| US11680925B2 (en) | 2014-11-25 | 2023-06-20 | Polymer Technology Systems, Inc. | Systems and methods for electrochemical hematocrit determination by alternate current impedance phase angle determinations |
| US20170328924A1 (en) | 2014-11-26 | 2017-11-16 | Ronald Jones | Automated microscopic cell analysis |
| US11478789B2 (en) | 2014-11-26 | 2022-10-25 | Medica Corporation | Automated microscopic cell analysis |
| WO2018009920A1 (en) | 2016-07-08 | 2018-01-11 | Medica Corporation | Automated microscopic cell analysis |
| US10061972B2 (en) | 2015-05-28 | 2018-08-28 | Tokitae Llc | Image analysis systems and related methods |
| US20200041325A1 (en) | 2015-06-19 | 2020-02-06 | Andrew Alliance S.A. | Devices and methods for measurement of liquid volumes |
| JP6461739B2 (ja) | 2015-07-28 | 2019-01-30 | 富士フイルム株式会社 | 画像処理装置及び内視鏡システム並びに画像処理装置の作動方法 |
| DE102015113557B4 (de) | 2015-08-17 | 2019-05-02 | Gerresheimer Regensburg Gmbh | Probenvorrichtung mit Referenzmarkierung |
| EP3859425B1 (en) | 2015-09-17 | 2024-04-17 | S.D. Sight Diagnostics Ltd. | Methods and apparatus for detecting an entity in a bodily sample |
| US10921112B2 (en) | 2015-09-17 | 2021-02-16 | Technion Research & Development Foundation Ltd. | Reflectance confocal microscopy of blood cells |
| JP6559555B2 (ja) | 2015-12-02 | 2019-08-14 | 株式会社日立エルジーデータストレージ | 光計測方法および装置 |
| US10416087B2 (en) | 2016-01-01 | 2019-09-17 | Kla-Tencor Corporation | Systems and methods for defect detection using image reconstruction |
| CA3018536A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Distinguishing between blood sample components |
| US10281386B2 (en) | 2016-05-11 | 2019-05-07 | Bonraybio Co., Ltd. | Automated testing apparatus |
| EP3455626B1 (en) | 2016-05-11 | 2025-08-06 | S.D. Sight Diagnostics Ltd. | Performing optical measurements on a sample |
| EP4177593A1 (en) | 2016-05-11 | 2023-05-10 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| WO2018063914A1 (en) | 2016-09-29 | 2018-04-05 | Animantis, Llc | Methods and apparatus for assessing immune system activity and therapeutic efficacy |
| KR102669330B1 (ko) | 2016-12-01 | 2024-05-28 | 버클리 라잇츠, 인크. | 미세유체 디바이스에서의 마이크로-객체의 자동화된 검출 및 재포지셔닝 |
| CN111183350A (zh) | 2017-08-17 | 2020-05-19 | 雅培医护站股份有限公司 | 用于对血细胞成像的单次使用测试设备 |
| JP6505792B2 (ja) | 2017-08-29 | 2019-04-24 | 富士フイルム株式会社 | 内視鏡用光源装置及び内視鏡システム |
| CN111788471B (zh) | 2017-11-14 | 2023-12-12 | 思迪赛特诊断有限公司 | 用于光学测量的样品载体 |
| WO2019102277A1 (en) | 2017-11-23 | 2019-05-31 | Sigtuple Technologies Private Limited | Method and system for determining hematological parameters in a peripheral blood smear |
| WO2019198094A1 (en) | 2018-04-09 | 2019-10-17 | Sigtuple Technologies Private Limited | Method and system for estimating total count of blood cells in a blood smear |
| JP7678424B2 (ja) | 2018-05-10 | 2025-05-16 | 学校法人順天堂 | 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法 |
| MX2022004703A (es) | 2019-10-22 | 2022-05-11 | S D Sight Diagnostics Ltd | Contabilidad de errores en mediciones opticas. |
| CA3160702A1 (en) | 2019-12-12 | 2021-06-17 | S.D. Sight Diagnostics Ltd | Artificial generation of a color blood smear image |
-
2017
- 2017-05-11 EP EP17728277.9A patent/EP3455626B1/en active Active
- 2017-05-11 WO PCT/IL2017/050526 patent/WO2017195208A1/en not_active Ceased
- 2017-05-11 US US16/099,270 patent/US11099175B2/en active Active
- 2017-05-11 CN CN201780027908.3A patent/CN109564209B/zh active Active
- 2017-05-11 JP JP2018558180A patent/JP6942148B2/ja active Active
- 2017-05-11 CN CN202210483679.9A patent/CN115266540B/zh active Active
- 2017-05-11 CA CA3022770A patent/CA3022770A1/en active Pending
- 2017-05-11 AU AU2017263807A patent/AU2017263807B2/en active Active
-
2018
- 2018-11-15 ZA ZA2018/07687A patent/ZA201807687B/en unknown
-
2020
- 2020-10-28 US US17/082,615 patent/US12174175B2/en active Active
-
2021
- 2021-06-28 US US17/360,503 patent/US12181463B2/en active Active
- 2021-09-07 JP JP2021145455A patent/JP7253014B2/ja active Active
-
2024
- 2024-11-19 US US18/951,911 patent/US20250076287A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021193385A (ja) | 2021-12-23 |
| EP3455626C0 (en) | 2025-08-06 |
| AU2017263807A1 (en) | 2018-11-01 |
| US20250076287A1 (en) | 2025-03-06 |
| ZA201807687B (en) | 2021-05-26 |
| US12181463B2 (en) | 2024-12-31 |
| JP7253014B2 (ja) | 2023-04-05 |
| US20210325373A1 (en) | 2021-10-21 |
| CN109564209A (zh) | 2019-04-02 |
| US20210041422A1 (en) | 2021-02-11 |
| US12174175B2 (en) | 2024-12-24 |
| AU2017263807B2 (en) | 2023-02-02 |
| EP3455626A1 (en) | 2019-03-20 |
| EP3455626B1 (en) | 2025-08-06 |
| CN115266540A (zh) | 2022-11-01 |
| CN115266540B (zh) | 2025-11-28 |
| CN109564209B (zh) | 2022-05-31 |
| BR112018072627A2 (pt) | 2019-02-19 |
| US20190145963A1 (en) | 2019-05-16 |
| WO2017195208A1 (en) | 2017-11-16 |
| JP2019522774A (ja) | 2019-08-15 |
| US11099175B2 (en) | 2021-08-24 |
| CA3022770A1 (en) | 2017-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7253014B2 (ja) | 試料に対する光学測定の実施 | |
| EP4073508B1 (en) | Detecting platelets in a blood sample | |
| EP3350644B1 (en) | Methods and apparatus for detecting an entity in a bodily sample | |
| Fenech et al. | HUMN project initiative and review of validation, quality control and prospects for further development of automated micronucleus assays using image cytometry systems | |
| Yüksel et al. | Comparison of fully automated urine sediment analyzers H800‐FUS100 and Labumat‐Urised with manual microscopy | |
| CN114787611A (zh) | 考虑光学测量的误差 | |
| EP2698622B1 (en) | A cell analyzer and cell analyzing method | |
| JP6378599B2 (ja) | 細胞分析方法および細胞分析装置 | |
| Khejonnit et al. | Optimal criteria for microscopic review of urinalysis following use of automated urine analyzer | |
| Smith et al. | Single-step preparation and image-based counting of minute volumes of human blood | |
| EP4073685A1 (en) | Classification models for analyzing a sample | |
| Larkey et al. | Advances and progress in automated urine analyzers | |
| Hernandez | Comparison of the Performance of the IDEXX SediVue Dx® with Manual Microscopy for Detection of Cells and Crystals in Urine Sediments | |
| US20230221297A1 (en) | Methodology of accuracy and precision determination for a new urine sediment analyzer | |
| BR112018072627B1 (pt) | Realização de medições óticas em uma amostra |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200511 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20200511 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20210324 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20210330 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210629 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20210810 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20210907 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6942148 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |