FR2884920B1 - Dispositif et procede d'analyse multiparametrique d'elements microscopiques - Google Patents

Dispositif et procede d'analyse multiparametrique d'elements microscopiques

Info

Publication number
FR2884920B1
FR2884920B1 FR0504005A FR0504005A FR2884920B1 FR 2884920 B1 FR2884920 B1 FR 2884920B1 FR 0504005 A FR0504005 A FR 0504005A FR 0504005 A FR0504005 A FR 0504005A FR 2884920 B1 FR2884920 B1 FR 2884920B1
Authority
FR
France
Prior art keywords
microscopic elements
multiparametric analysis
multiparametric
analysis
microscopic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0504005A
Other languages
English (en)
Other versions
FR2884920A1 (fr
Inventor
Philippe Nerin
Didier Lefevre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Horiba ABX SAS
Original Assignee
Horiba ABX SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0504005A priority Critical patent/FR2884920B1/fr
Application filed by Horiba ABX SAS filed Critical Horiba ABX SAS
Priority to EP06743693A priority patent/EP1875197A2/fr
Priority to KR1020077027024A priority patent/KR20080007473A/ko
Priority to JP2008507118A priority patent/JP2008537136A/ja
Priority to CN2006800208234A priority patent/CN101194159B/zh
Priority to PCT/FR2006/000819 priority patent/WO2006111641A2/fr
Priority to US11/912,055 priority patent/US7777869B2/en
Publication of FR2884920A1 publication Critical patent/FR2884920A1/fr
Application granted granted Critical
Publication of FR2884920B1 publication Critical patent/FR2884920B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N15/149—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486—Counting the particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1493—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
FR0504005A 2005-04-21 2005-04-21 Dispositif et procede d'analyse multiparametrique d'elements microscopiques Expired - Fee Related FR2884920B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0504005A FR2884920B1 (fr) 2005-04-21 2005-04-21 Dispositif et procede d'analyse multiparametrique d'elements microscopiques
KR1020077027024A KR20080007473A (ko) 2005-04-21 2006-04-14 미시적 요소들의 다중매개변수 분석을 위한 기기 및 방법
JP2008507118A JP2008537136A (ja) 2005-04-21 2006-04-14 微視的要素のマルチパラメトリック分析のための装置及び方法
CN2006800208234A CN101194159B (zh) 2005-04-21 2006-04-14 微观元素多参数分析设备和方法
EP06743693A EP1875197A2 (fr) 2005-04-21 2006-04-14 Dispositif et procede d'analyse multiparametrique d'elements microscopiques
PCT/FR2006/000819 WO2006111641A2 (fr) 2005-04-21 2006-04-14 Dispositif et procede d'analyse multiparametrique d'elements microscopiques
US11/912,055 US7777869B2 (en) 2005-04-21 2006-04-14 Device and method for multiparametric analysis of microscopic elements

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0504005A FR2884920B1 (fr) 2005-04-21 2005-04-21 Dispositif et procede d'analyse multiparametrique d'elements microscopiques

Publications (2)

Publication Number Publication Date
FR2884920A1 FR2884920A1 (fr) 2006-10-27
FR2884920B1 true FR2884920B1 (fr) 2007-08-10

Family

ID=34955254

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0504005A Expired - Fee Related FR2884920B1 (fr) 2005-04-21 2005-04-21 Dispositif et procede d'analyse multiparametrique d'elements microscopiques

Country Status (7)

Country Link
US (1) US7777869B2 (fr)
EP (1) EP1875197A2 (fr)
JP (1) JP2008537136A (fr)
KR (1) KR20080007473A (fr)
CN (1) CN101194159B (fr)
FR (1) FR2884920B1 (fr)
WO (1) WO2006111641A2 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2756225A1 (fr) 2009-03-25 2010-09-30 Los Alamos National Security, Llc Ensemble a fibres optiques pour spectrometrie par fluorescence
CN102365096A (zh) * 2009-03-25 2012-02-29 洛斯阿拉莫斯国家安全有限责任公司 传染剂的快速死前检测
FR2956207B1 (fr) * 2010-02-10 2012-05-04 Horiba Abx Sas Dispositif et procede de mesures multiparametriques de microparticules dans un fluide
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
FR2971337B1 (fr) * 2011-02-04 2013-03-01 Horiba Abx Sas Dispositif et procede de mesures multiparametriques de microparticules dans un fluide
GB2492950A (en) * 2011-07-11 2013-01-23 Cambridge Consultants Measuring a luminescent property of a sample using a dual-modulated excitation beam
WO2013059835A1 (fr) * 2011-10-21 2013-04-25 Acea Biosciences, Inc. Système et procédé permettant de détecter une lumière induite par plusieurs sources d'excitation dans un canal de circulation
WO2013098821A1 (fr) 2011-12-29 2013-07-04 Parasight Ltd. Procédés et systèmes de détection de pathogène dans un prélèvement biologique
EP2999988A4 (fr) 2013-05-23 2017-01-11 S.D. Sight Diagnostics Ltd. Procédé et système d'imagerie de prélèvement cellulaire
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
EP3039477B1 (fr) 2013-08-26 2021-10-20 S.D. Sight Diagnostics Ltd. Systèmes, procédés et produits programmes d'ordinateur de microscopie numérique
US10261080B2 (en) 2013-11-19 2019-04-16 Acea Biosciences, Inc. Optical detection system for flow cytometer, flow cytometer system and methods of use
US9575063B2 (en) 2013-11-19 2017-02-21 Acea Biosciences, Inc. Optical engine for flow cytometer, flow cytometer system and methods of use
MX2016011193A (es) * 2014-02-28 2016-12-16 Life Technologies Corp Sistemas, metodos y aparatos para sistemas opticos en citometros de flujo.
US9869628B2 (en) 2014-06-25 2018-01-16 Acea Biosciences, Inc. Methods of collecting cells from multi-well plates for use in flow cytometry
WO2016030897A1 (fr) 2014-08-27 2016-03-03 S.D. Sight Diagnostics Ltd Système et procédé de calcul de variation de focalisation pour un microscope numérique
JP6352750B2 (ja) * 2014-09-26 2018-07-04 シスメックス株式会社 血液分析装置および血液分析方法
JP6370659B2 (ja) * 2014-09-26 2018-08-08 シスメックス株式会社 血液分析装置および血液分析方法
CN108474934B (zh) 2015-09-17 2022-01-18 思迪赛特诊断有限公司 用于检测身体样本中实体的方法和设备
CA3018536A1 (fr) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Distinction entre les composants d'un echantillon de sang
EP4177593A1 (fr) 2016-05-11 2023-05-10 S.D. Sight Diagnostics Ltd. Support d'échantillon pour mesures optiques
US11099175B2 (en) 2016-05-11 2021-08-24 S.D. Sight Diagnostics Ltd. Performing optical measurements on a sample
WO2017216123A1 (fr) 2016-06-13 2017-12-21 Nanolive Sa Procédé de caractérisation et d'imagerie d'objets microscopiques
CN109964133A (zh) * 2016-10-31 2019-07-02 惠普发展公司，有限责任合伙企业 同位素的电参数
USD869676S1 (en) 2017-03-28 2019-12-10 Becton, Dickinson And Company Particle sorting module
USD868991S1 (en) 2017-03-28 2019-12-03 Becton, Dickinson And Company Register block
WO2019097387A1 (fr) 2017-11-14 2019-05-23 S.D. Sight Diagnostics Ltd Porte-échantillon pour mesures optiques
EP3514600A1 (fr) * 2018-01-19 2019-07-24 Leica Instruments (Singapore) Pte. Ltd. Procédé de normalisation d'intensité de fluorescence
USD872296S1 (en) 2018-01-30 2020-01-07 Becton, Dickinson And Company Particle sorting module
USD882817S1 (en) 2018-01-30 2020-04-28 Becton, Dickinson And Company Sample container
USD876668S1 (en) 2018-01-30 2020-02-25 Becton, Dickinson And Company Particle sorting module mount
USD864415S1 (en) 2018-01-30 2019-10-22 Becton, Dickinson And Company Particle sorting system
DE102018114697B4 (de) * 2018-06-19 2023-02-16 Krohne Messtechnik Gmbh Messvorrichtung und Verfahren zur zeitaufgelösten Messung eines Messsignals
KR102122020B1 (ko) * 2018-09-04 2020-06-12 경북대학교 산학협력단 혈구 분석 장치, 이를 이용한 혈구 분석 방법
US20210396642A1 (en) * 2020-06-18 2021-12-23 Wyatt Technology Corporation Calculating molar mass values of components of and molar mass concentration values of conjugate molecules/particles
KR102435974B1 (ko) * 2020-09-28 2022-08-24 (주)티에스테크 멀티 측정모듈을 이용한 미세먼지 측정 장치

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735504A (en) * 1983-10-31 1988-04-05 Technicon Instruments Corporation Method and apparatus for determining the volume & index of refraction of particles
US4573796A (en) * 1984-01-06 1986-03-04 The United States Of America As Represented By The United States Department Of Energy Apparatus for eliminating background interference in fluorescence measurements
WO1992008120A1 (fr) * 1990-10-29 1992-05-14 Macquarie University Cytometrie en flux a laser impulsionnel
US5303026A (en) * 1991-02-26 1994-04-12 The Regents Of The University Of California Los Alamos National Laboratory Apparatus and method for spectroscopic analysis of scattering media
US5270548A (en) * 1992-07-31 1993-12-14 The United States Of America As Represented By The United States Department Of Energy Phase-sensitive flow cytometer
DK0660936T3 (da) * 1992-09-14 1999-05-25 Stanford Res Inst Int Op-konverterende reportermolekyle til biologiske og andre assays under anvendelse af laserexcitationsteknik
JPH06186155A (ja) * 1992-10-21 1994-07-08 Toa Medical Electronics Co Ltd 粒子分析装置
US5418371A (en) * 1993-02-01 1995-05-23 Aslund; Nils R. D. Apparatus for quantitative imaging of multiple fluorophores using dual detectors
US5986271A (en) * 1997-07-03 1999-11-16 Lazarev; Victor Fluorescence imaging system
US20070096039A1 (en) * 2002-05-03 2007-05-03 Rakesh Kapoor Evaluation Of Multicomponent Mixtures Using Modulated Light Beams
US20030205682A1 (en) * 2002-05-03 2003-11-06 Rakesh Kapoor Evaluation of multicomponent mixtures using modulated light beams
JP4598766B2 (ja) * 2003-04-29 2010-12-15 エス３アイ， エル エル シィ 生物学的微粒子及び非生物学的微粒子を検出し且つ分類するためのマルチスペクトル光学方法及びシステム

Also Published As

Publication number Publication date
CN101194159B (zh) 2012-05-02
JP2008537136A (ja) 2008-09-11
EP1875197A2 (fr) 2008-01-09
CN101194159A (zh) 2008-06-04
WO2006111641A2 (fr) 2006-10-26
WO2006111641A3 (fr) 2007-01-04
KR20080007473A (ko) 2008-01-21
FR2884920A1 (fr) 2006-10-27
US20080283754A1 (en) 2008-11-20
US7777869B2 (en) 2010-08-17

Similar Documents

Publication Publication Date Title
FR2884920B1 (fr) Dispositif et procede d'analyse multiparametrique d'elements microscopiques
FR2893159B1 (fr) Procede et dispositif pour l'analyse de circuits integres
FR2933513B1 (fr) Procede et dispositif d'analyse frequentielle de donnees
FR2885712B1 (fr) Dispositif et procede d'analyse semantique de documents par constitution d'arbres n-aire et semantique
FR2890867B1 (fr) Dispositif et procede d'assistance respiratoire
FR2857750B1 (fr) Dispositif et procede de prelevement pour un automate d'analyse
FR2872922B1 (fr) Procede et appareil d'acquisition vribratoire sismique
FR2893132B1 (fr) Dispositif d'analyse a balayage d'echantillons biologiques par fluorescence
FR2910616B1 (fr) Dispositif et procede d'assistance au choix d'aeroports de deroutement
FR2849696B1 (fr) Dispositif de fabrication de specimen et procede de fabrication de specimen
FR2890747B1 (fr) Methode et dispositif d'analyse de composes chimiques
FR2897873B1 (fr) Procede d'analyse microbiologique rapide.
FR2884094B1 (fr) Dispositif d'analyse d'image
FR2925163B1 (fr) Procede et appareil d'analyse thermique
FR2942899B1 (fr) Dispositif et procede d'analyse optique de documents
FR2912213B1 (fr) Dispositif et procede pour evaluer l'exposition sonore d'un individu
FR2904417B1 (fr) "dispositif et procede de prelevement utilisable dans un automate d'analyse"
FR2958411B1 (fr) Procede d'analyse spectrometrique et dispositif apparente
FR2871896B1 (fr) Procede et dispositif pour sonder la matiere nucleaire par photofission
FR2902080B1 (fr) Dispositif et procede de suveillance d'un aeronef
DE202004015484U1 (de) Probenbearbeitungsvorrichtung und Probenanalysevorrichtung
FR2883088B1 (fr) Dispositif et procede de suivi d'aeronefs
FR2899972B1 (fr) Dispositif et procede d'analyse d'echantillon biologique par spectroscopie resolue spatialement
FR2905587B1 (fr) Dispositif et procede d'analyse temporelle de l'agitation d'un patient alite.
FR2903916B1 (fr) Dispositif microfluidique pour la cristallisation et l'analyse cristallographique de molecules

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

PLFP Fee payment

Year of fee payment: 14

PLFP Fee payment

Year of fee payment: 15

PLFP Fee payment

Year of fee payment: 16

ST Notification of lapse

Effective date: 20211205