MX2022007121A - Imagenes microscopicas desenfocadas de una muestra. - Google Patents

Imagenes microscopicas desenfocadas de una muestra.

Info

Publication number
MX2022007121A
MX2022007121A MX2022007121A MX2022007121A MX2022007121A MX 2022007121 A MX2022007121 A MX 2022007121A MX 2022007121 A MX2022007121 A MX 2022007121A MX 2022007121 A MX2022007121 A MX 2022007121A MX 2022007121 A MX2022007121 A MX 2022007121A
Authority
MX
Mexico
Prior art keywords
sample
microscope
focus
level
focal plane
Prior art date
Application number
MX2022007121A
Other languages
English (en)
Inventor
Sharon Pecker
Yochay Shlomo Eshel
Amir Zait
Dan Gluck
Yafin Arnon Houri
Joseph Joel Pollak
Yonatan Halperin
Peretz Yafin
Sarah Levy
Dana Benbassat
David Brailovsky
Uriyah Pumerantz
Original Assignee
S D Sight Diagnostics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S D Sight Diagnostics Ltd filed Critical S D Sight Diagnostics Ltd
Publication of MX2022007121A publication Critical patent/MX2022007121A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Radiology & Medical Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Signal Processing (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Focus Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Image Analysis (AREA)
  • Microscoopes, Condenser (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Se describen aparatos y métodos para sus usos con una muestra corporal que contiene células. Se enfoca un microscopio (24), de manera que un plano focal del microscopio (24) coincide al menos aproximadamente con un nivel en el que al menos algunas células pertenecientes a la muestra se disponen al menos parcialmente. Al menos una imagen microscópica enfocada de la muestra, mientras que el plano focal del microscopio (24) coincide aproximadamente con el nivel. El microscopio (24) se enfoca de manera que el plano focal del microscopio está desplazado con respecto al nivel, se adquiere al menos una imagen microscópica desenfocada de la muestra, mientras que el plano focal del microscopio (24) se desplaza con respeto al nivel. Se determina una propiedad de al menos una porción de la muestra, al menos parcialmente en base a las imágenes enfocadas y desenfocadas. También se describen otras aplicaciones.
MX2022007121A 2019-12-12 2020-12-10 Imagenes microscopicas desenfocadas de una muestra. MX2022007121A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962946985P 2019-12-12 2019-12-12
US202063048692P 2020-07-07 2020-07-07
PCT/IB2020/061728 WO2021116957A1 (en) 2019-12-12 2020-12-10 Off-focus microscopic images of a sample

Publications (1)

Publication Number Publication Date
MX2022007121A true MX2022007121A (es) 2022-07-11

Family

ID=73856204

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022007121A MX2022007121A (es) 2019-12-12 2020-12-10 Imagenes microscopicas desenfocadas de una muestra.

Country Status (10)

Country Link
US (1) US20230011382A1 (es)
EP (1) EP4073491A1 (es)
JP (1) JP2023506417A (es)
CN (1) CN114829900A (es)
AU (1) AU2020402284A1 (es)
BR (1) BR112022011255A2 (es)
CA (1) CA3160692A1 (es)
MX (1) MX2022007121A (es)
WO (1) WO2021116957A1 (es)
ZA (1) ZA202206312B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022009104A2 (en) 2020-07-07 2022-01-13 S.D. Sight Diagnostics Ltd Focusing a microscope using fluorescent images
WO2023144713A1 (en) 2022-01-25 2023-08-03 S.D. Sight Diagnostics Ltd Sample carrier for use with a bodily sample

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5040191B2 (ja) * 2006-06-29 2012-10-03 富士通株式会社 マイクロインジェクション装置及び自動焦点調整方法
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
US10640807B2 (en) 2011-12-29 2020-05-05 S.D. Sight Diagnostics Ltd Methods and systems for detecting a pathogen in a biological sample
JP5464244B2 (ja) * 2012-08-24 2014-04-09 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
EP2999988A4 (en) 2013-05-23 2017-01-11 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for obtaining a monolayer of cells, for use specifically for diagnosis
EP3955042A1 (en) 2013-08-26 2022-02-16 S.D. Sight Diagnostics Ltd. Digital microscopy systems, methods and computer program products
US10482595B2 (en) 2014-08-27 2019-11-19 S.D. Sight Diagnostics Ltd. System and method for calculating focus variation for a digital microscope
EP3350644B1 (en) 2015-09-17 2021-04-28 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
US11733150B2 (en) 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
CN109564209B (zh) 2016-05-11 2022-05-31 思迪赛特诊断有限公司 对样品实施的光学测量
EP4177593A1 (en) 2016-05-11 2023-05-10 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
WO2019097387A1 (en) 2017-11-14 2019-05-23 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements

Also Published As

Publication number Publication date
US20230011382A1 (en) 2023-01-12
CN114829900A (zh) 2022-07-29
ZA202206312B (en) 2023-02-22
JP2023506417A (ja) 2023-02-16
CA3160692A1 (en) 2021-06-17
EP4073491A1 (en) 2022-10-19
AU2020402284A1 (en) 2022-06-02
BR112022011255A2 (pt) 2022-09-06
WO2021116957A1 (en) 2021-06-17

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