JP6814814B2 - Ｔａａｒのアゴニストとしての活性を有する５−エチル−４−メチル−ピラゾール−３−カルボキサミド誘導体 - Google Patents
Ｔａａｒのアゴニストとしての活性を有する５−エチル−４−メチル−ピラゾール−３−カルボキサミド誘導体 Download PDFInfo
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- JP6814814B2 JP6814814B2 JP2018545336A JP2018545336A JP6814814B2 JP 6814814 B2 JP6814814 B2 JP 6814814B2 JP 2018545336 A JP2018545336 A JP 2018545336A JP 2018545336 A JP2018545336 A JP 2018545336A JP 6814814 B2 JP6814814 B2 JP 6814814B2
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Landscapes
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| PCT/EP2017/055885 WO2017157873A1 (en) | 2016-03-17 | 2017-03-14 | 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar |
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| AU2021238632A1 (en) * | 2020-03-19 | 2022-07-14 | F. Hoffmann-La Roche Ag | Salts and crystalline forms of a TAAR1 agonist |
| EP4430032A1 (en) | 2021-11-08 | 2024-09-18 | F. Hoffmann-La Roche AG | Catalytic hydrogenation of aromatic nitro compounds |
| CN114288304A (zh) * | 2021-12-31 | 2022-04-08 | 江苏海洋大学 | 一种抗精神分裂症组合物及其应用 |
| AR129909A1 (es) | 2022-07-15 | 2024-10-09 | Hoffmann La Roche | Cetorreductasa mutante con mayor actividad de cetorreductasa así como métodos y usos de esta |
| KR20250044870A (ko) | 2022-08-12 | 2025-04-01 | 에프. 호프만-라 로슈 아게 | 5-에틸-4-메틸-n-[4-[(2s) 모르폴린-2-일]페닐]-1h-피라졸-3-카르복스아미드를 포함하는 약제학적 조성물 |
| EP4568654A1 (en) * | 2022-08-12 | 2025-06-18 | F. Hoffmann-La Roche AG | Use of co-processed excipients in continuous manufacturing of solid dosage forms |
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| US2161938A (en) | 1934-07-31 | 1939-06-13 | Soc Of Chemical Ind | Imidazolines |
| US2457047A (en) | 1946-02-13 | 1948-12-21 | Monsanto Chemicals | 2-(2'-thenyl)-4, 5-dihydroimidazoles and process for making the same |
| DE842065C (de) | 1950-07-30 | 1952-06-23 | Bayer Ag | Verfahren zur Herstellung stickstoffhaltiger heterocyclischer Verbindungen |
| US2778836A (en) | 1954-04-02 | 1957-01-22 | Union Chimique Belge Sa | Substituted 2-methyl-delta2 imidazolines |
| US2744910A (en) | 1955-06-27 | 1956-05-08 | Bristol Lab Inc | 2-(ortho-benzylbenzyl)-imidazoline and acid addition salts |
| US2744909A (en) | 1955-06-27 | 1956-05-08 | Bristol Lab Inc | 2-(ortho-phenylbenzyl) imidazoline and acid addition salts |
| US2919274A (en) | 1957-09-17 | 1959-12-29 | Sahyun Melville | Amidines |
| GB877306A (en) | 1958-04-21 | 1961-09-13 | Pfizer & Co C | Halogenated derivatives of tetrahydro-1-naphthyl cyclic amidines |
| DE1083803B (de) | 1958-05-30 | 1960-06-23 | Bayer Ag | Verfahren zur Herstellung von Derivaten der Anthranil-N-carbonsaeure |
| DE1121054B (de) | 1960-11-23 | 1962-01-04 | Merck Ag E | Verfahren zur Herstellung eines neuen Imidazolinderivates und dessen Saeureadditionssalzen |
| US3202660A (en) | 1961-10-09 | 1965-08-24 | Boehringer Sohn Ingelheim | Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes |
| DE1150180B (de) | 1962-04-12 | 1963-06-12 | Merck Ag E | Mittel zur Vorbehandlung der Haut fuer die Rasur |
| FR1355049A (fr) | 1962-04-12 | 1964-03-13 | Merck Ag E | Agent pour le traitement préalable de la peau en vue du rasage |
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