JP6811857B2 - Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ - Google Patents

Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ Download PDF

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JP6811857B2
JP6811857B2 JP2019520125A JP2019520125A JP6811857B2 JP 6811857 B2 JP6811857 B2 JP 6811857B2 JP 2019520125 A JP2019520125 A JP 2019520125A JP 2019520125 A JP2019520125 A JP 2019520125A JP 6811857 B2 JP6811857 B2 JP 6811857B2
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seq
meganuclease
genetically engineered
hbv
sequence
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JP2019530462A (ja
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ジャンツ，デレック
スミス，ジェームス，ジェファーソン
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プレシジョン バイオサイエンシズ，インク．
プレシジョン バイオサイエンシズ，インク．
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JP2019520125A 2016-10-14 2017-10-13 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ Active JP6811857B2 (ja)

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JP2020207369A JP6919049B2 (ja) 2016-10-14 2020-12-15 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ

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US201662408356P 2016-10-14 2016-10-14
US62/408,356 2016-10-14
US201762452506P 2017-01-31 2017-01-31
US62/452,506 2017-01-31
US201762527196P 2017-06-30 2017-06-30
US201762527159P 2017-06-30 2017-06-30
US62/527,196 2017-06-30
US62/527,159 2017-06-30
PCT/US2017/056638 WO2018071849A2 (en) 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome

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JP2019530462A5 JP2019530462A5 (cg-RX-API-DMAC7.html) 2020-11-19
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JP2020207369A Active JP6919049B2 (ja) 2016-10-14 2020-12-15 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ
JP2021120133A Pending JP2021180665A (ja) 2016-10-14 2021-07-21 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ
JP2023115696A Pending JP2023153824A (ja) 2016-10-14 2023-07-14 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ
JP2025087808A Pending JP2025138637A (ja) 2016-10-14 2025-05-27 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ

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JP2021120133A Pending JP2021180665A (ja) 2016-10-14 2021-07-21 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ
JP2023115696A Pending JP2023153824A (ja) 2016-10-14 2023-07-14 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ
JP2025087808A Pending JP2025138637A (ja) 2016-10-14 2025-05-27 Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ

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KR (4) KR20230010826A (cg-RX-API-DMAC7.html)
CN (2) CN110023495A (cg-RX-API-DMAC7.html)
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JP2021061841A (ja) * 2016-10-14 2021-04-22 プレシジョン バイオサイエンシズ，インク． Ｂ型肝炎ウイルスゲノムの認識配列に特異的な遺伝子操作メガヌクレアーゼ
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US12410418B2 (en) 2019-12-06 2025-09-09 Precision Biosciences, Inc. Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome

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TWI815194B (zh) 2020-10-22 2023-09-11 美商基利科學股份有限公司 介白素2-Fc融合蛋白及使用方法
CA3172481A1 (en) * 2020-11-12 2022-05-19 Precision Biosciences, Inc. Engineered meganucleases having specificity for recognition sequences in the dystrophin gene
AU2022274607A1 (en) 2021-05-13 2023-11-16 Gilead Sciences, Inc. COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS
WO2024124044A1 (en) 2022-12-07 2024-06-13 The Brigham And Women’S Hospital, Inc. Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
WO2024192141A1 (en) 2023-03-13 2024-09-19 Dana-Farber Cancer Institute, Inc. Treatment of cancers having a drug-resistant mesenchymal cell state
WO2024226838A2 (en) 2023-04-25 2024-10-31 The Brigham And Women's Hospital, Inc. Treatment of autoimmune diseases having a pathogenic t cell state
AU2024270764A1 (en) 2023-05-15 2025-12-04 Nchroma Bio, Inc. Compositions and methods for epigenetic regulation of hbv gene expression
WO2025049788A1 (en) 2023-08-29 2025-03-06 The Broad Institute, Inc. Optical genetic screens of intracellular and intercellular transcriptional circuits with perturb-fish
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