JP5869745B2 - 25−ヒドロキシビタミンd2及び25−ヒドロキシビタミンd3によるビタミンd不足及び欠乏の治療 - Google Patents
25−ヒドロキシビタミンd2及び25−ヒドロキシビタミンd3によるビタミンd不足及び欠乏の治療 Download PDFInfo
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- JP5869745B2 JP5869745B2 JP2008553520A JP2008553520A JP5869745B2 JP 5869745 B2 JP5869745 B2 JP 5869745B2 JP 2008553520 A JP2008553520 A JP 2008553520A JP 2008553520 A JP2008553520 A JP 2008553520A JP 5869745 B2 JP5869745 B2 JP 5869745B2
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- hydroxyvitamin
- formulation
- release oral
- oral dosage
- vitamin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Botany (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76466506P | 2006-02-03 | 2006-02-03 | |
| US60/764,665 | 2006-02-03 | ||
| PCT/US2007/061521 WO2007092755A2 (en) | 2006-02-03 | 2007-02-02 | Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014011219A Division JP6023731B2 (ja) | 2006-02-03 | 2014-01-24 | 25−ヒドロキシビタミンd2及び25−ヒドロキシビタミンd3によるビタミンd不足及び欠乏の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009525985A JP2009525985A (ja) | 2009-07-16 |
| JP2009525985A5 JP2009525985A5 (OSRAM) | 2010-03-25 |
| JP5869745B2 true JP5869745B2 (ja) | 2016-02-24 |
Family
ID=38134147
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008553520A Active JP5869745B2 (ja) | 2006-02-03 | 2007-02-02 | 25−ヒドロキシビタミンd2及び25−ヒドロキシビタミンd3によるビタミンd不足及び欠乏の治療 |
| JP2014011219A Active JP6023731B2 (ja) | 2006-02-03 | 2014-01-24 | 25−ヒドロキシビタミンd2及び25−ヒドロキシビタミンd3によるビタミンd不足及び欠乏の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014011219A Active JP6023731B2 (ja) | 2006-02-03 | 2014-01-24 | 25−ヒドロキシビタミンd2及び25−ヒドロキシビタミンd3によるビタミンd不足及び欠乏の治療 |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US8426391B2 (OSRAM) |
| EP (3) | EP1993559B1 (OSRAM) |
| JP (2) | JP5869745B2 (OSRAM) |
| CA (2) | CA2882048C (OSRAM) |
| CY (2) | CY1118017T1 (OSRAM) |
| DK (2) | DK3095447T3 (OSRAM) |
| ES (3) | ES2593047T3 (OSRAM) |
| HK (1) | HK1256920A1 (OSRAM) |
| HU (2) | HUE029572T2 (OSRAM) |
| LT (2) | LT3095447T (OSRAM) |
| PL (2) | PL1993559T3 (OSRAM) |
| PT (2) | PT3095447T (OSRAM) |
| SI (2) | SI1993559T1 (OSRAM) |
| WO (1) | WO2007092755A2 (OSRAM) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1993559T1 (sl) | 2006-02-03 | 2017-01-31 | Opko Renal, Llc | Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3 |
| PT2679228T (pt) | 2006-06-21 | 2018-04-16 | Opko Ireland Global Holdings Ltd | Terapia utilizando um agente de repleção de vitamina d e um agente de substituição hormonal de vitamina d |
| CN104257667B (zh) * | 2007-04-25 | 2019-06-04 | 欧普科Ip 控股Ii 有限公司 | 治疗维生素d不足和缺乏、继发性甲状旁腺功能亢进症和维生素d-响应疾病的方法和组合物 |
| EP3225243B1 (en) | 2007-04-25 | 2025-09-03 | Opko Renal, LLC | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
| KR101959952B1 (ko) | 2007-04-25 | 2019-03-19 | 사이토크로마 인코포레이티드 | 비타민 d 화합물과 밀랍성 담체를 포함하는 경구 조절성 방출 조성물 |
| CA2684778C (en) * | 2007-04-25 | 2017-09-05 | Cytochroma Inc. | Methods and compounds for vitamin d therapy |
| MX2010008896A (es) * | 2008-02-13 | 2010-11-05 | Dsm Ip Assets Bv | Tratamiento de hipertension con 25-hidroxi-vitamina d3. |
| EP2240183A1 (en) * | 2008-02-13 | 2010-10-20 | DSM IP Assets B.V. | Combination of vitamin d and 25-hydroxyvitamin d 3 |
| CN104758301A (zh) * | 2008-02-13 | 2015-07-08 | 帝斯曼知识产权资产管理有限公司 | 维生素d3和25-羟基-维生素d3的组合用途 |
| WO2009101137A1 (en) * | 2008-02-13 | 2009-08-20 | Dsm Ip Assets B.V. | Use of 25-hydroxy-vitamin d3 to affect human muscle physiology |
| BRPI0907950A2 (pt) * | 2008-02-13 | 2015-08-04 | Dsm Ip Assets Bv | Tratamento de hiperglicemia com 25-hidroxivitamina d3 |
| CN106853250A (zh) | 2008-04-02 | 2017-06-16 | 赛特克罗公司 | 用于维生素d缺乏症和相关障碍的方法、组合物、用途和试剂盒 |
| AU2009273889B2 (en) * | 2008-07-24 | 2013-01-31 | Wisconsin Alumni Research Foundation | Once-a-week administration of 25-hydroxy vitamin D3 to sustain elevated steady-state pharmacokinetic blood concentration |
| EP2289555A1 (en) * | 2009-08-24 | 2011-03-02 | OrgaNext Research B.V. | Method of treating frailty |
| AU2010309784B2 (en) * | 2009-10-20 | 2016-11-10 | Herbonis Ag | Composition comprising Solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing blood calcium levels |
| ES2783980T3 (es) | 2010-03-29 | 2020-09-21 | Opko Ireland Global Holdings Ltd | Métodos y composiciones para la reducción de niveles de paratiroides |
| US20140273021A1 (en) | 2013-03-14 | 2014-09-18 | Enzo Biochem, Inc. | Vitamin d assays |
| KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
| US10220047B2 (en) * | 2014-08-07 | 2019-03-05 | Opko Ireland Global Holdings, Ltd. | Adjunctive therapy with 25-hydroxyvitamin D and articles therefor |
| EP3053598A1 (en) * | 2015-02-06 | 2016-08-10 | Faes Farma, S.A. | Calcifediol soft capsules |
| MY198547A (en) | 2016-03-28 | 2023-09-04 | Opko Ireland Global Holdings Ltd | Methods of vitamin d treatment |
| JP6829101B2 (ja) * | 2017-02-17 | 2021-02-10 | 株式会社ファンケル | 上気道感染症予防又は上気道感染症状緩和用経口組成物 |
| JP7590184B2 (ja) | 2018-04-03 | 2024-11-26 | オプコ アイルランド グローバル ホールディングス リミテッド | 肥満外科手術患者におけるカルシフェジオールの使用 |
| KR20210054539A (ko) | 2018-08-31 | 2021-05-13 | 옵코 아일랜드 글로벌 홀딩스 리미티드 | 비타민 d의 소아용 투여 형태, 이의 제조 및 사용 |
| AU2020218639A1 (en) | 2019-02-06 | 2021-08-12 | Eirgen Pharma Ltd. | Method of controlling progression of hyperparathyroidism with calcifediol, and compositions for use therein |
| US20230084354A1 (en) * | 2020-01-27 | 2023-03-16 | Biomics, Llc | Nutraceutical extracts of hippophae rhamnoides and terminalia chebula and uses thereof |
| WO2021205225A1 (en) | 2020-04-06 | 2021-10-14 | Eirgen Pharma Ltd. | 25-hydroxyvitamin d for the treatment of sars-cov-2 infection |
| CN115768412A (zh) | 2020-05-31 | 2023-03-07 | 艾尔金制药有限公司 | 硬胶囊剂型和其用途 |
| WO2025094144A1 (en) | 2023-11-02 | 2025-05-08 | Eirgen Pharma Ltd. | Controlling loss of kidney function |
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