NO971934L - Flourinerte vitamin D3 -analoger - Google Patents

Flourinerte vitamin D3 -analoger

Info

Publication number
NO971934L
NO971934L NO971934A NO971934A NO971934L NO 971934 L NO971934 L NO 971934L NO 971934 A NO971934 A NO 971934A NO 971934 A NO971934 A NO 971934A NO 971934 L NO971934 L NO 971934L
Authority
NO
Norway
Prior art keywords
analogues
fluorinated vitamin
disorders
hydroxyl
hydrogen
Prior art date
Application number
NO971934A
Other languages
English (en)
Other versions
NO971934D0 (no
Inventor
Bernard Michael Hennessy
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO971934D0 publication Critical patent/NO971934D0/no
Publication of NO971934L publication Critical patent/NO971934L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelse med formel I HO^ hvor R er hydrogen, fluor eller hydroksyl, og X er =CH2 eller når R er hydroksyl, er X hydrogen eller =CH2 er anvendelig ved behandling av hyperprolifera- tive lidelser, neoplastiske lidelser og talgkjertel- lidelser.
NO971934A 1996-05-23 1997-04-25 Flourinerte vitamin D3 -analoger NO971934L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1818796P 1996-05-23 1996-05-23

Publications (2)

Publication Number Publication Date
NO971934D0 NO971934D0 (no) 1997-04-25
NO971934L true NO971934L (no) 1997-11-24

Family

ID=21786696

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971934A NO971934L (no) 1996-05-23 1997-04-25 Flourinerte vitamin D3 -analoger

Country Status (30)

Country Link
US (1) US5888994A (no)
EP (1) EP0808831B1 (no)
JP (1) JP2858571B2 (no)
KR (1) KR100237523B1 (no)
CN (1) CN1081184C (no)
AR (1) AR007240A1 (no)
AT (1) ATE195514T1 (no)
AU (1) AU720098B2 (no)
BR (1) BR9703373A (no)
CA (1) CA2204478C (no)
CO (1) CO4840512A1 (no)
CZ (1) CZ157997A3 (no)
DE (1) DE69702812T2 (no)
DK (1) DK0808831T3 (no)
ES (1) ES2150719T3 (no)
GR (1) GR3034832T3 (no)
HR (1) HRP970274A2 (no)
HU (1) HUP9700927A3 (no)
IL (1) IL120842A0 (no)
MA (1) MA24345A1 (no)
NO (1) NO971934L (no)
NZ (1) NZ314838A (no)
PL (1) PL320131A1 (no)
PT (1) PT808831E (no)
SG (1) SG50831A1 (no)
TR (1) TR199700418A2 (no)
TW (1) TW374762B (no)
UY (1) UY24563A1 (no)
YU (1) YU19997A (no)
ZA (1) ZA974334B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
WO1998051678A1 (en) * 1997-05-16 1998-11-19 Women & Infants Hospital CYCLIC ETHER VITAMIN D3 COMPOUNDS, 1α (OH) 3-EPI-VITAMIN D3 COMPOUNDS AND USES THEREOF
EP0981514B1 (en) * 1997-05-16 2006-04-05 Woman & Infants Hospital 3-epi vitamin d2 compounds and uses thereof
AU1022999A (en) * 1997-09-08 1999-03-29 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
WO2000051554A2 (en) * 1999-03-05 2000-09-08 Johns Hopkins University Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20080293647A1 (en) 2004-11-12 2008-11-27 Luciano Adorini Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
SI3095447T1 (sl) 2006-02-03 2022-02-28 Opko Renal, Llc Zdravljenje pomanjkanja vitamina D s 25-hidroksivitaminom D2 in 25-hidroksivitaminom D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
DK2148661T3 (da) 2007-04-25 2013-03-25 Cytochroma Inc Orale præparater med kontrolleret afgivelse omfattende vitamin D-forbindelse og voksagtig bærer
EP2148684B1 (en) 2007-04-25 2013-01-16 Cytochroma Inc. Method of treating vitamin d insufficiency and deficiency
CA2797537C (en) 2010-03-29 2021-11-23 Cytochroma Inc. Use of 25-hydroxyvitamin d compound for reducing parathyroid levels
WO2012065050A1 (en) 2010-11-12 2012-05-18 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
KR20230054752A (ko) 2016-03-28 2023-04-25 옵코 아일랜드 글로벌 홀딩스 리미티드 비타민 d 치료 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039671A (en) * 1984-12-19 1991-08-13 Hoffmann-La Roche Inc. Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) * 1991-08-27 1993-05-11 Daikin Industries, Ltd. Vitamin d3 analogues
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
DE69304279T2 (de) * 1992-05-20 1997-02-20 Hoffmann La Roche Fluorierte Analoge Vitamins D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
TW267161B (no) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger

Also Published As

Publication number Publication date
HUP9700927A2 (hu) 1998-01-28
CA2204478C (en) 2006-11-21
SG50831A1 (en) 1998-07-20
AU2357297A (en) 1997-11-27
EP0808831A2 (en) 1997-11-26
PT808831E (pt) 2000-12-29
HU9700927D0 (en) 1997-07-28
KR100237523B1 (ko) 2000-01-15
ES2150719T3 (es) 2000-12-01
BR9703373A (pt) 1998-09-15
US5888994A (en) 1999-03-30
JP2858571B2 (ja) 1999-02-17
TW374762B (en) 1999-11-21
MA24345A1 (fr) 1998-07-01
TR199700418A3 (tr) 1997-12-21
AR007240A1 (es) 1999-10-27
NO971934D0 (no) 1997-04-25
HRP970274A2 (en) 1998-04-30
ATE195514T1 (de) 2000-09-15
CO4840512A1 (es) 1999-09-27
DK0808831T3 (da) 2001-01-02
AU720098B2 (en) 2000-05-25
CZ157997A3 (en) 1997-12-17
JPH1045712A (ja) 1998-02-17
PL320131A1 (en) 1997-11-24
GR3034832T3 (en) 2001-02-28
CN1081184C (zh) 2002-03-20
DE69702812D1 (de) 2000-09-21
UY24563A1 (es) 2000-12-29
HUP9700927A3 (en) 1999-07-28
NZ314838A (en) 1998-01-26
TR199700418A2 (xx) 1997-12-21
ZA974334B (en) 1997-11-24
IL120842A0 (en) 1997-09-30
CN1169425A (zh) 1998-01-07
EP0808831B1 (en) 2000-08-16
EP0808831A3 (en) 1999-02-03
KR970074763A (ko) 1997-12-10
DE69702812T2 (de) 2001-01-25
CA2204478A1 (en) 1997-11-23
YU19997A (sh) 1999-07-28
MX9703776A (es) 1998-06-30

Similar Documents

Publication Publication Date Title
NO971934L (no) Flourinerte vitamin D3 -analoger
NO972304L (no) Vitamin D3-analoger
GB2102287B (en) Use of aromatase-inhibitors with antiandrogens for treatment of prostatic hyperplasia.
NO983266L (no) Distribuert Behandling
ZA899251B (en) Hypocholesterolemic and antiatherosclerotic uses of bis(3,5-ditertiary-butyl-4-hydroxyphenylthio)methane
DE69409148D1 (de) Verfahren zur Herstellung von Wasserstoffperoxid
NO894201L (no) Badetilsetningsmiddel.
ID24308A (id) Plasma darah yang dapat diaplikasikan secara universal
NO20056021L (no) Anvendelse av CS-866 til fremstilling av et medikament
ATE141914T1 (de) Fluorierte analoge vitamins d3
MX9703024A (es) Cristalizacion de levobupivacaina y sus analogos.
NO934197L (no) Vitamin D-3-analoger
DE3476847D1 (en) A remedial or prophylactic agent for the treatment of seizures
NO973366L (no) Fremgangsmåte for behandling av multippel sklerose
DK0520372T3 (da) Inositol-phosphat-analoger som calciumantagonistiske stoffer
ECSP972130A (es) Analogos de vitamina d3 - fluorinados
EP0796843A3 (en) 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
GR3034688T3 (en) Use of 6,7-substituted-2-aminotetralines for preparing pharmaceutical compositions useful for the treatment of septic shock, and antipyretic and antiinflammatory pharmaceutical compositions
MX9708190A (es) Metodo para tratar dioxido de cloro.
FI934442A7 (fi) Katalysoitu menetelmä hypokloriitti-ionien hajottamiseksi
ATE174965T1 (de) Verfahren zur herstellung von halogenierten hydroxyphenylessigsäuren
MD259C2 (ro) Metodă de tratament al maladiei ulceroase a duodenului, complicată cu stenoză piloroduodenală
IT1244888B (it) Procedimento per la sintesi di composti aromatici fluorurati
ECSP972129A (es) Analogos de vitamina d3
GR960100116A (el) Μεθοδος παρασκευης 1-κυκλοπροπυλο-6-φλουορο-1,4-διυδρο-7-[(1s,4s)-5-μεθυλο-2,5-διαζαβικυκλο[2.2.1]-επτ-2-υλο] -4-οξο-3-κουινολινοκαρβοξυλικο οξυ και αλατα αυτων.