MX9703024A - Cristalizacion de levobupivacaina y sus analogos. - Google Patents
Cristalizacion de levobupivacaina y sus analogos.Info
- Publication number
- MX9703024A MX9703024A MX9703024A MX9703024A MX9703024A MX 9703024 A MX9703024 A MX 9703024A MX 9703024 A MX9703024 A MX 9703024A MX 9703024 A MX9703024 A MX 9703024A MX 9703024 A MX9703024 A MX 9703024A
- Authority
- MX
- Mexico
- Prior art keywords
- levobupivacaine
- crystallisation
- analogues
- resolving agent
- analogue
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Epoxy Compounds (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Abstract
La levobupivacaína o un análogo de la misma se prepara por la reaccion con el agente de resolucion ácido tartárico en un solvente, en presencia de agua y/o menos de 0.5 equivalente del agente de resolucion.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9421476A GB9421476D0 (en) | 1994-10-25 | 1994-10-25 | Process and salt |
GBGB9504926.8A GB9504926D0 (en) | 1995-03-10 | 1995-03-10 | Crystallisation |
PCT/GB1995/002513 WO1996012699A1 (en) | 1994-10-25 | 1995-10-23 | Crystallisation of levobupivacaine and analogues thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9703024A true MX9703024A (es) | 1997-10-31 |
Family
ID=26305863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9703024A MX9703024A (es) | 1994-10-25 | 1995-10-23 | Cristalizacion de levobupivacaina y sus analogos. |
Country Status (16)
Country | Link |
---|---|
US (1) | US5994548A (es) |
EP (1) | EP0788480B1 (es) |
JP (1) | JP3911545B2 (es) |
AT (1) | ATE245629T1 (es) |
AU (1) | AU698637B2 (es) |
CA (1) | CA2200355C (es) |
DE (1) | DE69531356T2 (es) |
DK (1) | DK0788480T3 (es) |
ES (1) | ES2202375T3 (es) |
FI (1) | FI117438B (es) |
HU (1) | HU227420B1 (es) |
MX (1) | MX9703024A (es) |
NO (1) | NO309266B1 (es) |
PL (1) | PL183210B1 (es) |
PT (1) | PT788480E (es) |
WO (1) | WO1996012699A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
BRPI0104491B8 (pt) * | 2001-10-10 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica. |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
AU2003299659A1 (en) | 2002-12-13 | 2004-07-09 | Durect Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
US6790267B1 (en) * | 2003-04-24 | 2004-09-14 | Xerox Corporation | Colorant compositions |
US7094812B2 (en) * | 2003-04-24 | 2006-08-22 | Xerox Corporations | Colorant compositions |
JP5285275B2 (ja) | 2004-09-17 | 2013-09-11 | デュレクト コーポレーション | 制御されたデリバリーシステム |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
EP2010491A1 (en) * | 2006-04-25 | 2009-01-07 | Disham Pharmaceuticals and Chemicals Ltd. | Ropivacaine hydrochloride anhydrate and the preparation thereof |
AU2007325918B2 (en) | 2006-11-03 | 2013-10-17 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
JP2011506318A (ja) | 2007-12-06 | 2011-03-03 | デュレクト コーポレーション | 経口医薬製剤 |
ATE555093T1 (de) * | 2008-01-15 | 2012-05-15 | Pharmathen Sa | Verfahren zur herstellung einer (s)-1-alkyl-2i,6i-pipecoloxylididverbindung |
US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
CN103073484B (zh) * | 2013-01-28 | 2014-10-22 | 山东诚创医药技术开发有限公司 | 一种甲哌卡因及其光学对映体的制备方法 |
CA2905131A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
JP2020503324A (ja) * | 2016-12-26 | 2020-01-30 | セリックス バイオ プライヴェート リミテッドCellix Bio Private Limited | 慢性疼痛の処置のための組成物及び方法 |
KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE341404B (es) * | 1967-05-18 | 1971-12-27 | Sterling Drug Inc | |
US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
-
1995
- 1995-10-23 AU AU37048/95A patent/AU698637B2/en not_active Expired
- 1995-10-23 US US08/849,418 patent/US5994548A/en not_active Expired - Lifetime
- 1995-10-23 WO PCT/GB1995/002513 patent/WO1996012699A1/en active IP Right Grant
- 1995-10-23 CA CA002200355A patent/CA2200355C/en not_active Expired - Lifetime
- 1995-10-23 PT PT95934738T patent/PT788480E/pt unknown
- 1995-10-23 PL PL95319829A patent/PL183210B1/pl unknown
- 1995-10-23 DE DE69531356T patent/DE69531356T2/de not_active Expired - Lifetime
- 1995-10-23 MX MX9703024A patent/MX9703024A/es unknown
- 1995-10-23 AT AT95934738T patent/ATE245629T1/de active
- 1995-10-23 ES ES95934738T patent/ES2202375T3/es not_active Expired - Lifetime
- 1995-10-23 HU HU9702372A patent/HU227420B1/hu unknown
- 1995-10-23 JP JP51373896A patent/JP3911545B2/ja not_active Expired - Lifetime
- 1995-10-23 EP EP95934738A patent/EP0788480B1/en not_active Expired - Lifetime
- 1995-10-23 DK DK95934738T patent/DK0788480T3/da active
-
1997
- 1997-04-22 FI FI971711A patent/FI117438B/fi not_active IP Right Cessation
- 1997-04-24 NO NO971903A patent/NO309266B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO971903L (no) | 1997-04-24 |
JPH10507464A (ja) | 1998-07-21 |
FI971711A0 (fi) | 1997-04-22 |
CA2200355A1 (en) | 1996-05-02 |
PL319829A1 (en) | 1997-09-01 |
PL183210B1 (pl) | 2002-06-28 |
AU698637B2 (en) | 1998-11-05 |
JP3911545B2 (ja) | 2007-05-09 |
EP0788480B1 (en) | 2003-07-23 |
ES2202375T3 (es) | 2004-04-01 |
AU3704895A (en) | 1996-05-15 |
WO1996012699A1 (en) | 1996-05-02 |
FI971711A (fi) | 1997-04-22 |
US5994548A (en) | 1999-11-30 |
NO309266B1 (no) | 2001-01-08 |
DE69531356D1 (de) | 2003-08-28 |
EP0788480A1 (en) | 1997-08-13 |
CA2200355C (en) | 2007-03-06 |
ATE245629T1 (de) | 2003-08-15 |
HUT77631A (hu) | 1998-06-29 |
NO971903D0 (no) | 1997-04-24 |
DK0788480T3 (da) | 2003-09-29 |
FI117438B (fi) | 2006-10-13 |
DE69531356T2 (de) | 2004-05-27 |
HU227420B1 (en) | 2011-05-30 |
PT788480E (pt) | 2003-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9703024A (es) | Cristalizacion de levobupivacaina y sus analogos. | |
DE69204484T2 (de) | Verfahren zur Herstellung von Wasserstoffperoxyd. | |
DE69101775T2 (de) | Verfahren zur Herstellung von Wasserstoffperoxid. | |
ATE57176T1 (de) | Verfahren zur herstellung von (2,2)-paracyclophan und dessen abkoemmlinge. | |
DE60026844D1 (de) | Verfahren zur herstellung von 3,3-dimethylbutanal | |
ATE153022T1 (de) | 3',5'-ditertbutyl-4'-hydroxyflavone, verfahren zu ihrer herstellung und pharmazeutische zusammensetzung mit antioxidations- und antivasokonstriktionsaktivität | |
DE69407653D1 (de) | Verfahren zur Herstellung von Wasserstoffsuperoxyd | |
FI955130A (fi) | L-aminohappo-oksidaasi | |
EP0260869A3 (en) | Deodorant composition | |
DE69202680D1 (de) | Verfahren zur Herstellung von Wasserstoffperoxyd. | |
DE59407675D1 (de) | Verfahren zur Herstellung von 6H-Dibenz-(c,e)(1,2)-oxaphosphorin-6-on | |
DE69401368D1 (de) | Verfahren zur Herstellung von 1,4-Dicyano-2-buten | |
AU638829B2 (en) | Composition for disinfecting water by the electrochlorination process and use of this composition | |
DE69427148T2 (de) | Verfahren zur Herstellung von 2,4,5-Tribrompyrrol-3-carbonitril | |
TW332199B (en) | Process for the preparation of 3-chloropropionic acid | |
DE68911323T2 (de) | Verfahren zur Herstellung eines Elektrokatalysators. | |
AU2403592A (en) | 2-aza-2-desamino analogues of 5,8-dideazafolic acid | |
DE69423702D1 (de) | Verfahren zur Herstellung von 6,13-Dihydroquinacridonen | |
DE69226016D1 (de) | Verfahren zur Herstellung von 2,4,5-Trihalobenzoesäure | |
DE69126610D1 (de) | Darstellung von 3,4,6-trifluorophthalsäure | |
MY114151A (en) | Analogs of thymosin | |
AU8241091A (en) | The use of formamidine sulfinic acid as an oxygen scavenger | |
AU590447B2 (en) | Chemical blowing agent compositions and methods | |
AU590447C (en) | Chemical blowing agent compositions and methods | |
DE59401293D1 (de) | Verfahren zur Herstellung von 1,3,5-Triacetylbenzol |