PT788480E - Cristalizacao de levobupivacaina e seus analogos - Google Patents
Cristalizacao de levobupivacaina e seus analogosInfo
- Publication number
- PT788480E PT788480E PT95934738T PT95934738T PT788480E PT 788480 E PT788480 E PT 788480E PT 95934738 T PT95934738 T PT 95934738T PT 95934738 T PT95934738 T PT 95934738T PT 788480 E PT788480 E PT 788480E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- levobupivacaine
- analogs
- crystallization
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Saccharide Compounds (AREA)
- Epoxy Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9421476A GB9421476D0 (en) | 1994-10-25 | 1994-10-25 | Process and salt |
| GBGB9504926.8A GB9504926D0 (en) | 1995-03-10 | 1995-03-10 | Crystallisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT788480E true PT788480E (pt) | 2003-12-31 |
Family
ID=26305863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT95934738T PT788480E (pt) | 1994-10-25 | 1995-10-23 | Cristalizacao de levobupivacaina e seus analogos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5994548A (pt) |
| EP (1) | EP0788480B1 (pt) |
| JP (1) | JP3911545B2 (pt) |
| AT (1) | ATE245629T1 (pt) |
| AU (1) | AU698637B2 (pt) |
| CA (1) | CA2200355C (pt) |
| DE (1) | DE69531356T2 (pt) |
| DK (1) | DK0788480T3 (pt) |
| ES (1) | ES2202375T3 (pt) |
| FI (1) | FI117438B (pt) |
| HU (1) | HU227420B1 (pt) |
| MX (1) | MX9703024A (pt) |
| NO (1) | NO309266B1 (pt) |
| PL (1) | PL183210B1 (pt) |
| PT (1) | PT788480E (pt) |
| WO (1) | WO1996012699A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| BRPI0104491B8 (pt) * | 2001-10-10 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica. |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| SI2218448T1 (sl) | 2002-12-13 | 2016-01-29 | Durect Corporation | Sistem za oralno dajanje zdravila, ki obsega tekoči nosilec materialov z visoko viskoznostjo |
| US7094812B2 (en) * | 2003-04-24 | 2006-08-22 | Xerox Corporations | Colorant compositions |
| US6790267B1 (en) * | 2003-04-24 | 2004-09-14 | Xerox Corporation | Colorant compositions |
| KR101351771B1 (ko) | 2004-09-17 | 2014-02-17 | 듀렉트 코퍼레이션 | 바람직하게 ｓａｉｂ와 같은 당 에스테르를 포함하는지속적인 국소 마취제 조성물 |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| WO2007123405A1 (en) * | 2006-04-25 | 2007-11-01 | Dishman Pharmaceuticals And Chemicals Ltd. | Ropivacaine hydrochloride anhydrate and the preparation thereof |
| PT2117521E (pt) | 2006-11-03 | 2012-09-10 | Durect Corp | Sistemas de administração transdérmica que compreendem bupivacaína |
| AU2008347158B8 (en) | 2007-12-06 | 2013-08-22 | Durect Corporation | Oral pharmaceutical dosage forms |
| DK2234974T3 (da) * | 2008-01-15 | 2012-06-25 | Pharmathen Sa | Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| CN103073484B (zh) * | 2013-01-28 | 2014-10-22 | 山东诚创医药技术开发有限公司 | 一种甲哌卡因及其光学对映体的制备方法 |
| EP2983468A4 (en) | 2013-03-15 | 2016-09-07 | Durect Corp | COMPOSITIONS WITH RHEOLOGY MODIFIER TO REDUCE RESOLUTION VARIABILITY |
| CN110325179A (zh) * | 2016-12-26 | 2019-10-11 | 塞尔利克斯生物私人有限公司 | 用于治疗慢性疼痛的组合物和方法 |
| WO2021146215A1 (en) | 2020-01-13 | 2021-07-22 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE341404B (pt) * | 1967-05-18 | 1971-12-27 | Sterling Drug Inc | |
| US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
-
1995
- 1995-10-23 DK DK95934738T patent/DK0788480T3/da active
- 1995-10-23 DE DE69531356T patent/DE69531356T2/de not_active Expired - Lifetime
- 1995-10-23 PL PL95319829A patent/PL183210B1/pl unknown
- 1995-10-23 WO PCT/GB1995/002513 patent/WO1996012699A1/en active IP Right Grant
- 1995-10-23 EP EP95934738A patent/EP0788480B1/en not_active Expired - Lifetime
- 1995-10-23 AT AT95934738T patent/ATE245629T1/de active
- 1995-10-23 HU HU9702372A patent/HU227420B1/hu unknown
- 1995-10-23 US US08/849,418 patent/US5994548A/en not_active Expired - Lifetime
- 1995-10-23 PT PT95934738T patent/PT788480E/pt unknown
- 1995-10-23 MX MX9703024A patent/MX9703024A/es unknown
- 1995-10-23 CA CA002200355A patent/CA2200355C/en not_active Expired - Lifetime
- 1995-10-23 AU AU37048/95A patent/AU698637B2/en not_active Expired
- 1995-10-23 JP JP51373896A patent/JP3911545B2/ja not_active Expired - Lifetime
- 1995-10-23 ES ES95934738T patent/ES2202375T3/es not_active Expired - Lifetime
-
1997
- 1997-04-22 FI FI971711A patent/FI117438B/fi not_active IP Right Cessation
- 1997-04-24 NO NO971903A patent/NO309266B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10507464A (ja) | 1998-07-21 |
| DE69531356D1 (de) | 2003-08-28 |
| DE69531356T2 (de) | 2004-05-27 |
| NO309266B1 (no) | 2001-01-08 |
| AU3704895A (en) | 1996-05-15 |
| EP0788480A1 (en) | 1997-08-13 |
| DK0788480T3 (da) | 2003-09-29 |
| WO1996012699A1 (en) | 1996-05-02 |
| PL319829A1 (en) | 1997-09-01 |
| HUT77631A (hu) | 1998-06-29 |
| HU227420B1 (en) | 2011-05-30 |
| ATE245629T1 (de) | 2003-08-15 |
| EP0788480B1 (en) | 2003-07-23 |
| FI971711A (fi) | 1997-04-22 |
| NO971903D0 (no) | 1997-04-24 |
| PL183210B1 (pl) | 2002-06-28 |
| AU698637B2 (en) | 1998-11-05 |
| CA2200355A1 (en) | 1996-05-02 |
| MX9703024A (es) | 1997-10-31 |
| JP3911545B2 (ja) | 2007-05-09 |
| US5994548A (en) | 1999-11-30 |
| NO971903L (no) | 1997-04-24 |
| ES2202375T3 (es) | 2004-04-01 |
| FI117438B (fi) | 2006-10-13 |
| CA2200355C (en) | 2007-03-06 |
| FI971711A0 (fi) | 1997-04-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT788480E (pt) | Cristalizacao de levobupivacaina e seus analogos | |
| DE59308619D1 (de) | Germicide wirkstoffkombinationen | |
| ATE148130T1 (de) | Typ-iv-dipeptidyl-aminopeptidase-inhibitoren | |
| DE69221501D1 (de) | Verfahren zum vermindern von durch medizinische vorrichtungen bedingten infektionen | |
| ES8609251A1 (es) | Un procedimiento para preparar un compuesto de n-aril-n- -(4-piperidinil)-alcoxialquilamida | |
| DE3880047D1 (de) | Zusammensetzung eines zusatzes. | |
| DK393288D0 (da) | Praeparat til saarheling og knogleregenerering | |
| DK0581959T3 (da) | Anvendelse af makrolidforbindelser til øjensygdomme | |
| ATE57176T1 (de) | Verfahren zur herstellung von (2,2)-paracyclophan und dessen abkoemmlinge. | |
| ATE153022T1 (de) | 3',5'-ditertbutyl-4'-hydroxyflavone, verfahren zu ihrer herstellung und pharmazeutische zusammensetzung mit antioxidations- und antivasokonstriktionsaktivität | |
| ES2140565T3 (es) | Nuevos derivados de pirazina-carboxamida, su preparacion y su utilizacion en medicamentos. | |
| DE69109401T2 (de) | Wässrige Zusammensetzungen zur Behandlung von porösen Substraten. | |
| FI951511A (fi) | IL-10:n käyttö insuliinista riippuvan diabetes mellituksen ennaltaestoon tai hoitoon | |
| ATE81976T1 (de) | 2-pyrimidinyl-1-piperazin-derivate zur behandlung von alkoholismus. | |
| DE59105224D1 (de) | Verfahren zur Herstellung von N-substituierten Pyrrolidonen. | |
| ES2106680B1 (es) | Composiciones acuosas conteniendo ciprofloxacino y utilizacion y procedimiento correspondientes. | |
| DE3764330D1 (de) | 2,2;6,6-diethylen-3-oxo-17alpha-pregn-4-en-21, 17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharm. praeparate. | |
| DE3750747D1 (de) | Chemische Behandlung von Likören. | |
| DE69103294T2 (de) | Verwendung der 3-Oxygermylpropionsäure zur Behandlung und Prävention von Diabetes verursacht durch Autoimmunkrankheiten. | |
| DE59303525D1 (de) | Verfahren zur Herstellung von N-(2-Hydroxypropyl)-2,6-dimethylmorpholin | |
| DE68928788T2 (de) | Verfahren zur Herstellung von optisch aktiven 3,4-Dihydroxybuttersäurederivaten | |
| ATE165344T1 (de) | Herstellung von symmetrischen und unsymmetrischen disubstituierten n-cyandithioiminocarbonaten | |
| ES2065843B1 (es) | Aplicacion de ent-11 , 16-dihidroxi-18-nor-4a -carboximetil-oxido de manoilo como inhibidor de la adenilatociclasa. | |
| KR890001568A (ko) | 돼지 이질의 예방 및 치료제 | |
| YU49004B (sh) | LANOSTA-7,9-DIEN-3Гџ, 32-DIOL I POSTUPAK ZA NJEGOVO DOBIJANJE |