FI971711A - Levobupivakaiinin ja sen analogien kiteyttäminen - Google Patents

Levobupivakaiinin ja sen analogien kiteyttäminen Download PDF

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Publication number
FI971711A
FI971711A FI971711A FI971711A FI971711A FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A
Authority
FI
Finland
Prior art keywords
pct
levobupivacaine
analogues
crystallization
sec
Prior art date
Application number
FI971711A
Other languages
English (en)
Swedish (sv)
Other versions
FI117438B (fi
FI971711A0 (fi
Inventor
Marianne Langston
Benjamin Mark Skead
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9421476A external-priority patent/GB9421476D0/en
Priority claimed from GBGB9504926.8A external-priority patent/GB9504926D0/en
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Publication of FI971711A publication Critical patent/FI971711A/fi
Publication of FI971711A0 publication Critical patent/FI971711A0/fi
Application granted granted Critical
Publication of FI117438B publication Critical patent/FI117438B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
FI971711A 1994-10-25 1997-04-22 Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi FI117438B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9421476 1994-10-25
GB9421476A GB9421476D0 (en) 1994-10-25 1994-10-25 Process and salt
GBGB9504926.8A GB9504926D0 (en) 1995-03-10 1995-03-10 Crystallisation
GB9504926 1995-03-10
GB9502513 1995-10-23
PCT/GB1995/002513 WO1996012699A1 (en) 1994-10-25 1995-10-23 Crystallisation of levobupivacaine and analogues thereof

Publications (3)

Publication Number Publication Date
FI971711A true FI971711A (fi) 1997-04-22
FI971711A0 FI971711A0 (fi) 1997-04-22
FI117438B FI117438B (fi) 2006-10-13

Family

ID=26305863

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971711A FI117438B (fi) 1994-10-25 1997-04-22 Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi

Country Status (16)

Country Link
US (1) US5994548A (fi)
EP (1) EP0788480B1 (fi)
JP (1) JP3911545B2 (fi)
AT (1) ATE245629T1 (fi)
AU (1) AU698637B2 (fi)
CA (1) CA2200355C (fi)
DE (1) DE69531356T2 (fi)
DK (1) DK0788480T3 (fi)
ES (1) ES2202375T3 (fi)
FI (1) FI117438B (fi)
HU (1) HU227420B1 (fi)
MX (1) MX9703024A (fi)
NO (1) NO309266B1 (fi)
PL (1) PL183210B1 (fi)
PT (1) PT788480E (fi)
WO (1) WO1996012699A1 (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0002246A (pt) * 2000-04-06 2003-04-15 Cristalia Prod Quimicos Farm Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis
BRPI0104491B8 (pt) * 2001-10-10 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica.
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
SI2218448T1 (sl) 2002-12-13 2016-01-29 Durect Corporation Sistem za oralno dajanje zdravila, ki obsega tekoči nosilec materialov z visoko viskoznostjo
US7094812B2 (en) * 2003-04-24 2006-08-22 Xerox Corporations Colorant compositions
US6790267B1 (en) * 2003-04-24 2004-09-14 Xerox Corporation Colorant compositions
KR101351771B1 (ko) 2004-09-17 2014-02-17 듀렉트 코퍼레이션 바람직하게 ｓａｉｂ와 같은 당 에스테르를 포함하는지속적인 국소 마취제 조성물
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
WO2007123405A1 (en) * 2006-04-25 2007-11-01 Dishman Pharmaceuticals And Chemicals Ltd. Ropivacaine hydrochloride anhydrate and the preparation thereof
PT2117521E (pt) 2006-11-03 2012-09-10 Durect Corp Sistemas de administração transdérmica que compreendem bupivacaína
AU2008347158B8 (en) 2007-12-06 2013-08-22 Durect Corporation Oral pharmaceutical dosage forms
DK2234974T3 (da) * 2008-01-15 2012-06-25 Pharmathen Sa Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
CN103073484B (zh) * 2013-01-28 2014-10-22 山东诚创医药技术开发有限公司 一种甲哌卡因及其光学对映体的制备方法
EP2983468A4 (en) 2013-03-15 2016-09-07 Durect Corp COMPOSITIONS WITH RHEOLOGY MODIFIER TO REDUCE RESOLUTION VARIABILITY
CN110325179A (zh) * 2016-12-26 2019-10-11 塞尔利克斯生物私人有限公司 用于治疗慢性疼痛的组合物和方法
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE341404B (fi) * 1967-05-18 1971-12-27 Sterling Drug Inc
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide

Also Published As

Publication number Publication date
JPH10507464A (ja) 1998-07-21
DE69531356D1 (de) 2003-08-28
DE69531356T2 (de) 2004-05-27
NO309266B1 (no) 2001-01-08
AU3704895A (en) 1996-05-15
EP0788480A1 (en) 1997-08-13
DK0788480T3 (da) 2003-09-29
WO1996012699A1 (en) 1996-05-02
PL319829A1 (en) 1997-09-01
HUT77631A (hu) 1998-06-29
HU227420B1 (en) 2011-05-30
ATE245629T1 (de) 2003-08-15
EP0788480B1 (en) 2003-07-23
NO971903D0 (no) 1997-04-24
PL183210B1 (pl) 2002-06-28
AU698637B2 (en) 1998-11-05
PT788480E (pt) 2003-12-31
CA2200355A1 (en) 1996-05-02
MX9703024A (es) 1997-10-31
JP3911545B2 (ja) 2007-05-09
US5994548A (en) 1999-11-30
NO971903L (no) 1997-04-24
ES2202375T3 (es) 2004-04-01
FI117438B (fi) 2006-10-13
CA2200355C (en) 2007-03-06
FI971711A0 (fi) 1997-04-22

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