DK2234974T3 - Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse - Google Patents
Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelseInfo
- Publication number
- DK2234974T3 DK2234974T3 DK08707040.5T DK08707040T DK2234974T3 DK 2234974 T3 DK2234974 T3 DK 2234974T3 DK 08707040 T DK08707040 T DK 08707040T DK 2234974 T3 DK2234974 T3 DK 2234974T3
- Authority
- DK
- Denmark
- Prior art keywords
- pipecoloxylidide
- alkyl
- compound
- preparation
- levobupivacaine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2008/000236 WO2009089841A1 (en) | 2008-01-15 | 2008-01-15 | Process for the preparation of (s)-1-alkyl-2',6'-pipecoloxylidide compound |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2234974T3 true DK2234974T3 (da) | 2012-06-25 |
Family
ID=39485172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08707040.5T DK2234974T3 (da) | 2008-01-15 | 2008-01-15 | Fremgangsmåde til fremstilling af (S)-1-alkyl-2',6'-pipecoloxylidid-forbindelse |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP2234974B1 (da) |
AT (1) | ATE555093T1 (da) |
CY (1) | CY1112979T1 (da) |
DK (1) | DK2234974T3 (da) |
ES (1) | ES2383714T3 (da) |
PL (1) | PL2234974T3 (da) |
PT (1) | PT2234974E (da) |
WO (1) | WO2009089841A1 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103073484B (zh) * | 2013-01-28 | 2014-10-22 | 山东诚创医药技术开发有限公司 | 一种甲哌卡因及其光学对映体的制备方法 |
WO2017036408A1 (zh) * | 2015-09-01 | 2017-03-09 | 四川海思科制药有限公司 | S-(-)-1-丙基-2',6'-二甲苯胺甲酰基哌啶晶体及其缓释制剂 |
CN105585520A (zh) * | 2015-12-24 | 2016-05-18 | 山东齐都药业有限公司 | 盐酸左布比卡因a晶型及其制备方法 |
CN113717094B (zh) * | 2021-08-11 | 2023-05-05 | 山东辰龙药业有限公司 | 一种制备甲哌卡因的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE40994T1 (de) * | 1983-08-01 | 1989-03-15 | Astra Laekemedel Ab | L-n-n-propylpipekolsaeure-2,6-xylidid und dessen herstellung. |
SE451840B (sv) * | 1986-01-03 | 1987-11-02 | Astra Laekemedel Ab | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
DK0788480T3 (da) * | 1994-10-25 | 2003-09-29 | Darwin Discovery Ltd | Krystallisering af levobupivacain og analoger deraf |
WO2007123405A1 (en) * | 2006-04-25 | 2007-11-01 | Dishman Pharmaceuticals And Chemicals Ltd. | Ropivacaine hydrochloride anhydrate and the preparation thereof |
-
2008
- 2008-01-15 WO PCT/EP2008/000236 patent/WO2009089841A1/en active Application Filing
- 2008-01-15 PL PL08707040T patent/PL2234974T3/pl unknown
- 2008-01-15 ES ES08707040T patent/ES2383714T3/es active Active
- 2008-01-15 EP EP08707040A patent/EP2234974B1/en active Active
- 2008-01-15 AT AT08707040T patent/ATE555093T1/de active
- 2008-01-15 DK DK08707040.5T patent/DK2234974T3/da active
- 2008-01-15 PT PT08707040T patent/PT2234974E/pt unknown
-
2012
- 2012-07-24 CY CY20121100654T patent/CY1112979T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2383714T3 (es) | 2012-06-25 |
EP2234974B1 (en) | 2012-04-25 |
CY1112979T1 (el) | 2016-04-13 |
PL2234974T3 (pl) | 2012-09-28 |
PT2234974E (pt) | 2012-05-29 |
WO2009089841A1 (en) | 2009-07-23 |
EP2234974A1 (en) | 2010-10-06 |
ATE555093T1 (de) | 2012-05-15 |
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