FI971711A - Kristallisering av levobupivakain och dess analoger - Google Patents
Kristallisering av levobupivakain och dess analoger Download PDFInfo
- Publication number
- FI971711A FI971711A FI971711A FI971711A FI971711A FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A
- Authority
- FI
- Finland
- Prior art keywords
- pct
- levobupivacaine
- analogues
- crystallization
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Epoxy Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9421476A GB9421476D0 (en) | 1994-10-25 | 1994-10-25 | Process and salt |
| GB9421476 | 1994-10-25 | ||
| GBGB9504926.8A GB9504926D0 (en) | 1995-03-10 | 1995-03-10 | Crystallisation |
| GB9504926 | 1995-03-10 | ||
| PCT/GB1995/002513 WO1996012699A1 (en) | 1994-10-25 | 1995-10-23 | Crystallisation of levobupivacaine and analogues thereof |
| GB9502513 | 1995-10-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI971711A true FI971711A (sv) | 1997-04-22 |
| FI971711A0 FI971711A0 (sv) | 1997-04-22 |
| FI117438B FI117438B (sv) | 2006-10-13 |
Family
ID=26305863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI971711A FI117438B (sv) | 1994-10-25 | 1997-04-22 | Förfarande för framställning av optiskt anrikat bupivakain |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5994548A (sv) |
| EP (1) | EP0788480B1 (sv) |
| JP (1) | JP3911545B2 (sv) |
| AT (1) | ATE245629T1 (sv) |
| AU (1) | AU698637B2 (sv) |
| CA (1) | CA2200355C (sv) |
| DE (1) | DE69531356T2 (sv) |
| DK (1) | DK0788480T3 (sv) |
| ES (1) | ES2202375T3 (sv) |
| FI (1) | FI117438B (sv) |
| HU (1) | HU227420B1 (sv) |
| MX (1) | MX9703024A (sv) |
| NO (1) | NO309266B1 (sv) |
| PL (1) | PL183210B1 (sv) |
| PT (1) | PT788480E (sv) |
| WO (1) | WO1996012699A1 (sv) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| BRPI0104491B8 (pt) * | 2001-10-10 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica. |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| SI1575569T1 (sl) * | 2002-12-13 | 2010-12-31 | Durect Corp | Oralni sistem dostave zdravila, ki obsega visokoviskozne tekoče nosilne materiale |
| US6790267B1 (en) * | 2003-04-24 | 2004-09-14 | Xerox Corporation | Colorant compositions |
| US7094812B2 (en) * | 2003-04-24 | 2006-08-22 | Xerox Corporations | Colorant compositions |
| BRPI0515372B8 (pt) | 2004-09-17 | 2021-05-25 | Durect Corp | composição líquida para fornecer anestesia local prolongada após administração a um indivíduo, e, uso de bupivacaína, acetato isobutirato de sacarose e álcool benzílico |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP2010491A1 (en) * | 2006-04-25 | 2009-01-07 | Disham Pharmaceuticals and Chemicals Ltd. | Ropivacaine hydrochloride anhydrate and the preparation thereof |
| PL2117521T3 (pl) | 2006-11-03 | 2012-11-30 | Durect Corp | Transdermalne systemy dostarczania zawierające bupiwakainę |
| AU2008347158B8 (en) | 2007-12-06 | 2013-08-22 | Durect Corporation | Oral pharmaceutical dosage forms |
| PT2234974E (pt) * | 2008-01-15 | 2012-05-29 | Pharmathen Sa | Processo para a preparação do composto (s)-l-alquil-2',6'- pipecoloxilidida |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| CN103073484B (zh) * | 2013-01-28 | 2014-10-22 | 山东诚创医药技术开发有限公司 | 一种甲哌卡因及其光学对映体的制备方法 |
| US9555113B2 (en) | 2013-03-15 | 2017-01-31 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| RU2021114918A (ru) * | 2016-12-26 | 2021-07-09 | Целликс Био Прайвет Лимитед | Композиции и способы лечения хронической боли |
| KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE341404B (sv) * | 1967-05-18 | 1971-12-27 | Sterling Drug Inc | |
| US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
-
1995
- 1995-10-23 CA CA002200355A patent/CA2200355C/en not_active Expired - Lifetime
- 1995-10-23 AT AT95934738T patent/ATE245629T1/de active
- 1995-10-23 WO PCT/GB1995/002513 patent/WO1996012699A1/en active IP Right Grant
- 1995-10-23 HU HU9702372A patent/HU227420B1/hu unknown
- 1995-10-23 DK DK95934738T patent/DK0788480T3/da active
- 1995-10-23 PT PT95934738T patent/PT788480E/pt unknown
- 1995-10-23 MX MX9703024A patent/MX9703024A/es unknown
- 1995-10-23 ES ES95934738T patent/ES2202375T3/es not_active Expired - Lifetime
- 1995-10-23 EP EP95934738A patent/EP0788480B1/en not_active Expired - Lifetime
- 1995-10-23 PL PL95319829A patent/PL183210B1/pl unknown
- 1995-10-23 DE DE69531356T patent/DE69531356T2/de not_active Expired - Lifetime
- 1995-10-23 US US08/849,418 patent/US5994548A/en not_active Expired - Lifetime
- 1995-10-23 AU AU37048/95A patent/AU698637B2/en not_active Expired
- 1995-10-23 JP JP51373896A patent/JP3911545B2/ja not_active Expired - Lifetime
-
1997
- 1997-04-22 FI FI971711A patent/FI117438B/sv not_active IP Right Cessation
- 1997-04-24 NO NO971903A patent/NO309266B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT788480E (pt) | 2003-12-31 |
| JP3911545B2 (ja) | 2007-05-09 |
| PL319829A1 (en) | 1997-09-01 |
| HU227420B1 (en) | 2011-05-30 |
| MX9703024A (es) | 1997-10-31 |
| NO309266B1 (no) | 2001-01-08 |
| WO1996012699A1 (en) | 1996-05-02 |
| DE69531356T2 (de) | 2004-05-27 |
| NO971903D0 (no) | 1997-04-24 |
| NO971903L (no) | 1997-04-24 |
| JPH10507464A (ja) | 1998-07-21 |
| PL183210B1 (pl) | 2002-06-28 |
| EP0788480B1 (en) | 2003-07-23 |
| HUT77631A (hu) | 1998-06-29 |
| FI117438B (sv) | 2006-10-13 |
| DK0788480T3 (da) | 2003-09-29 |
| AU3704895A (en) | 1996-05-15 |
| FI971711A0 (sv) | 1997-04-22 |
| AU698637B2 (en) | 1998-11-05 |
| ATE245629T1 (de) | 2003-08-15 |
| CA2200355A1 (en) | 1996-05-02 |
| DE69531356D1 (de) | 2003-08-28 |
| US5994548A (en) | 1999-11-30 |
| ES2202375T3 (es) | 2004-04-01 |
| EP0788480A1 (en) | 1997-08-13 |
| CA2200355C (en) | 2007-03-06 |
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| FG | Patent granted |
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| MA | Patent expired |