FI971711A0 - Levobupivakaiinin ja sen analogien kiteyttäminen - Google Patents
Levobupivakaiinin ja sen analogien kiteyttäminenInfo
- Publication number
- FI971711A0 FI971711A0 FI971711A FI971711A FI971711A0 FI 971711 A0 FI971711 A0 FI 971711A0 FI 971711 A FI971711 A FI 971711A FI 971711 A FI971711 A FI 971711A FI 971711 A0 FI971711 A0 FI 971711A0
- Authority
- FI
- Finland
- Prior art keywords
- pct
- levobupivacaine
- analogues
- crystallization
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Epoxy Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9421476A GB9421476D0 (en) | 1994-10-25 | 1994-10-25 | Process and salt |
| GB9421476 | 1994-10-25 | ||
| GB9504926 | 1995-03-10 | ||
| GBGB9504926.8A GB9504926D0 (en) | 1995-03-10 | 1995-03-10 | Crystallisation |
| PCT/GB1995/002513 WO1996012699A1 (en) | 1994-10-25 | 1995-10-23 | Crystallisation of levobupivacaine and analogues thereof |
| GB9502513 | 1995-10-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI971711A0 true FI971711A0 (fi) | 1997-04-22 |
| FI971711A FI971711A (fi) | 1997-04-22 |
| FI117438B FI117438B (fi) | 2006-10-13 |
Family
ID=26305863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI971711A FI117438B (fi) | 1994-10-25 | 1997-04-22 | Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5994548A (fi) |
| EP (1) | EP0788480B1 (fi) |
| JP (1) | JP3911545B2 (fi) |
| AT (1) | ATE245629T1 (fi) |
| AU (1) | AU698637B2 (fi) |
| CA (1) | CA2200355C (fi) |
| DE (1) | DE69531356T2 (fi) |
| DK (1) | DK0788480T3 (fi) |
| ES (1) | ES2202375T3 (fi) |
| FI (1) | FI117438B (fi) |
| HU (1) | HU227420B1 (fi) |
| MX (1) | MX9703024A (fi) |
| NO (1) | NO309266B1 (fi) |
| PL (1) | PL183210B1 (fi) |
| PT (1) | PT788480E (fi) |
| WO (1) | WO1996012699A1 (fi) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| BRPI0104491B8 (pt) * | 2001-10-10 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica. |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| CN101797221B (zh) | 2002-12-13 | 2013-06-12 | 杜雷科特公司 | 包含高粘度液体载体材料的口服递药系统 |
| US7094812B2 (en) * | 2003-04-24 | 2006-08-22 | Xerox Corporations | Colorant compositions |
| US6790267B1 (en) * | 2003-04-24 | 2004-09-14 | Xerox Corporation | Colorant compositions |
| SI2767292T1 (sl) | 2004-09-17 | 2017-01-31 | Durect Corporation | Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP2010491A1 (en) * | 2006-04-25 | 2009-01-07 | Disham Pharmaceuticals and Chemicals Ltd. | Ropivacaine hydrochloride anhydrate and the preparation thereof |
| ES2388355T3 (es) | 2006-11-03 | 2012-10-11 | Durect Corporation | Sistemas de suministro transdémico que comprenden bupivacaína |
| AU2008347158B8 (en) | 2007-12-06 | 2013-08-22 | Durect Corporation | Oral pharmaceutical dosage forms |
| PT2234974E (pt) * | 2008-01-15 | 2012-05-29 | Pharmathen Sa | Processo para a preparação do composto (s)-l-alquil-2',6'- pipecoloxilidida |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| CN103073484B (zh) * | 2013-01-28 | 2014-10-22 | 山东诚创医药技术开发有限公司 | 一种甲哌卡因及其光学对映体的制备方法 |
| WO2014144975A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| US11000487B2 (en) * | 2016-12-26 | 2021-05-11 | Cellix Bio Private Limited | Compositions and methods for the treatment of chronic pain |
| CN115666621A (zh) | 2020-01-13 | 2023-01-31 | 度勒科特公司 | 具有减少的杂质的持续释放药物递送系统及相关方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE341404B (fi) * | 1967-05-18 | 1971-12-27 | Sterling Drug Inc | |
| US4695576A (en) * | 1984-07-09 | 1987-09-22 | Astra Lake Medel Aktiebolag | L-N-n-propylpipecolic acid-2,6-xylidide |
-
1995
- 1995-10-23 DE DE69531356T patent/DE69531356T2/de not_active Expired - Lifetime
- 1995-10-23 HU HU9702372A patent/HU227420B1/hu unknown
- 1995-10-23 DK DK95934738T patent/DK0788480T3/da active
- 1995-10-23 ES ES95934738T patent/ES2202375T3/es not_active Expired - Lifetime
- 1995-10-23 AT AT95934738T patent/ATE245629T1/de active
- 1995-10-23 JP JP51373896A patent/JP3911545B2/ja not_active Expired - Lifetime
- 1995-10-23 AU AU37048/95A patent/AU698637B2/en not_active Expired
- 1995-10-23 PL PL95319829A patent/PL183210B1/pl unknown
- 1995-10-23 EP EP95934738A patent/EP0788480B1/en not_active Expired - Lifetime
- 1995-10-23 US US08/849,418 patent/US5994548A/en not_active Expired - Lifetime
- 1995-10-23 CA CA002200355A patent/CA2200355C/en not_active Expired - Lifetime
- 1995-10-23 WO PCT/GB1995/002513 patent/WO1996012699A1/en active IP Right Grant
- 1995-10-23 PT PT95934738T patent/PT788480E/pt unknown
- 1995-10-23 MX MX9703024A patent/MX9703024A/es unknown
-
1997
- 1997-04-22 FI FI971711A patent/FI117438B/fi not_active IP Right Cessation
- 1997-04-24 NO NO971903A patent/NO309266B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE245629T1 (de) | 2003-08-15 |
| NO971903D0 (no) | 1997-04-24 |
| JPH10507464A (ja) | 1998-07-21 |
| US5994548A (en) | 1999-11-30 |
| NO309266B1 (no) | 2001-01-08 |
| PT788480E (pt) | 2003-12-31 |
| DE69531356D1 (de) | 2003-08-28 |
| WO1996012699A1 (en) | 1996-05-02 |
| CA2200355C (en) | 2007-03-06 |
| EP0788480A1 (en) | 1997-08-13 |
| HUT77631A (hu) | 1998-06-29 |
| DE69531356T2 (de) | 2004-05-27 |
| AU3704895A (en) | 1996-05-15 |
| EP0788480B1 (en) | 2003-07-23 |
| PL183210B1 (pl) | 2002-06-28 |
| PL319829A1 (en) | 1997-09-01 |
| NO971903L (no) | 1997-04-24 |
| AU698637B2 (en) | 1998-11-05 |
| DK0788480T3 (da) | 2003-09-29 |
| JP3911545B2 (ja) | 2007-05-09 |
| HU227420B1 (en) | 2011-05-30 |
| MX9703024A (es) | 1997-10-31 |
| FI117438B (fi) | 2006-10-13 |
| ES2202375T3 (es) | 2004-04-01 |
| FI971711A (fi) | 1997-04-22 |
| CA2200355A1 (en) | 1996-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Ref document number: 117438 Country of ref document: FI |
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| MA | Patent expired |