YU19997A - Analozi fluorovanog vitamina d3 - Google Patents

Analozi fluorovanog vitamina d3

Info

Publication number
YU19997A
YU19997A YU19997A YU19997A YU19997A YU 19997 A YU19997 A YU 19997A YU 19997 A YU19997 A YU 19997A YU 19997 A YU19997 A YU 19997A YU 19997 A YU19997 A YU 19997A
Authority
YU
Yugoslavia
Prior art keywords
analogs
fluorinated vitamin
hydroxy
fluorinated
vitamin
Prior art date
Application number
YU19997A
Other languages
English (en)
Inventor
Bernard Michael Hennesy
Radoje Milan Uskoković
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Publication of YU19997A publication Critical patent/YU19997A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Jedinjenje formule I u kojoj R predstavlja vodonik, fluor ili hidroksi a X predstavlja =CH2 ili, kada je R hidroksi, X je vodonik ili =CH2, koja su korisna za lečenje hiperproliferativnih poremećaja, neoplastičnih bolesti i bolesti lojnih žlezda.
YU19997A 1996-05-23 1997-05-20 Analozi fluorovanog vitamina d3 YU19997A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1818796P 1996-05-23 1996-05-23

Publications (1)

Publication Number Publication Date
YU19997A true YU19997A (sh) 1999-07-28

Family

ID=21786696

Family Applications (1)

Application Number Title Priority Date Filing Date
YU19997A YU19997A (sh) 1996-05-23 1997-05-20 Analozi fluorovanog vitamina d3

Country Status (30)

Country Link
US (1) US5888994A (sh)
EP (1) EP0808831B1 (sh)
JP (1) JP2858571B2 (sh)
KR (1) KR100237523B1 (sh)
CN (1) CN1081184C (sh)
AR (1) AR007240A1 (sh)
AT (1) ATE195514T1 (sh)
AU (1) AU720098B2 (sh)
BR (1) BR9703373A (sh)
CA (1) CA2204478C (sh)
CO (1) CO4840512A1 (sh)
CZ (1) CZ157997A3 (sh)
DE (1) DE69702812T2 (sh)
DK (1) DK0808831T3 (sh)
ES (1) ES2150719T3 (sh)
GR (1) GR3034832T3 (sh)
HR (1) HRP970274A2 (sh)
HU (1) HUP9700927A3 (sh)
IL (1) IL120842A0 (sh)
MA (1) MA24345A1 (sh)
NO (1) NO971934L (sh)
NZ (1) NZ314838A (sh)
PL (1) PL320131A1 (sh)
PT (1) PT808831E (sh)
SG (1) SG50831A1 (sh)
TR (1) TR199700418A2 (sh)
TW (1) TW374762B (sh)
UY (1) UY24563A1 (sh)
YU (1) YU19997A (sh)
ZA (1) ZA974334B (sh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
US6100294A (en) 1997-05-16 2000-08-08 Women And Infants Hospital Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof
EP0981514B1 (en) * 1997-05-16 2006-04-05 Woman & Infants Hospital 3-epi vitamin d2 compounds and uses thereof
JP4219553B2 (ja) * 1997-09-08 2009-02-04 エフ．ホフマン−ラ ロシュ アーゲー １，３−ジヒドロキシ−２０，２０−ジアルキル−ビタミンｄ３類似体
WO2000051554A2 (en) * 1999-03-05 2000-09-08 Johns Hopkins University Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer
DK1993559T3 (en) 2006-02-03 2016-10-03 Opko Renal Llc Treatment of vitamin D deficiency and MALFUNCTION with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
ES2670029T3 (es) 2006-06-21 2018-05-29 Opko Ireland Global Holdings, Ltd. Terapia usando agente de repleción de la vitamina D y agente de reemplazo de la hormona de la vitamina D
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
DK2481400T3 (da) 2007-04-25 2014-09-29 Opko Ip Holdings Ii Inc Orale præparater med kontrolleret frigivelse omfattende en vitamin D-forbindelse og en voksagtig bærer
CN105796530A (zh) 2010-03-29 2016-07-27 赛特克罗公司 用于降低甲状旁腺水平的方法和组合物
WO2012065050A1 (en) 2010-11-12 2012-05-18 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
IL290855B2 (en) 2016-03-28 2024-06-01 Eirgen Pharma Ltd Treatment methods using vitamin D

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039671A (en) * 1984-12-19 1991-08-13 Hoffmann-La Roche Inc. Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) * 1991-08-27 1993-05-11 Daikin Industries, Ltd. Vitamin d3 analogues
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
ATE141914T1 (de) * 1992-05-20 1996-09-15 Hoffmann La Roche Fluorierte analoge vitamins d3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
TW267161B (sh) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger

Also Published As

Publication number Publication date
DK0808831T3 (da) 2001-01-02
EP0808831A3 (en) 1999-02-03
HRP970274A2 (en) 1998-04-30
GR3034832T3 (en) 2001-02-28
ATE195514T1 (de) 2000-09-15
ZA974334B (en) 1997-11-24
HUP9700927A3 (en) 1999-07-28
TR199700418A3 (tr) 1997-12-21
CN1081184C (zh) 2002-03-20
UY24563A1 (es) 2000-12-29
TR199700418A2 (xx) 1997-12-21
DE69702812D1 (de) 2000-09-21
CN1169425A (zh) 1998-01-07
CA2204478C (en) 2006-11-21
SG50831A1 (en) 1998-07-20
AU2357297A (en) 1997-11-27
ES2150719T3 (es) 2000-12-01
JPH1045712A (ja) 1998-02-17
MA24345A1 (fr) 1998-07-01
JP2858571B2 (ja) 1999-02-17
BR9703373A (pt) 1998-09-15
HUP9700927A2 (hu) 1998-01-28
CO4840512A1 (es) 1999-09-27
IL120842A0 (en) 1997-09-30
CZ157997A3 (en) 1997-12-17
DE69702812T2 (de) 2001-01-25
PL320131A1 (en) 1997-11-24
HU9700927D0 (en) 1997-07-28
KR970074763A (ko) 1997-12-10
NZ314838A (en) 1998-01-26
KR100237523B1 (ko) 2000-01-15
TW374762B (en) 1999-11-21
PT808831E (pt) 2000-12-29
US5888994A (en) 1999-03-30
NO971934L (no) 1997-11-24
MX9703776A (es) 1998-06-30
AU720098B2 (en) 2000-05-25
NO971934D0 (no) 1997-04-25
EP0808831A2 (en) 1997-11-26
AR007240A1 (es) 1999-10-27
EP0808831B1 (en) 2000-08-16
CA2204478A1 (en) 1997-11-23

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