YU20197A - Analozi vitamina d3, farmaceutske kompozicije koje ih sadrže kao aktivnu materiju i njihova upotreba u proizvodnji farmaceutskih kompozicija - Google Patents

Analozi vitamina d3, farmaceutske kompozicije koje ih sadrže kao aktivnu materiju i njihova upotreba u proizvodnji farmaceutskih kompozicija

Info

Publication number
YU20197A
YU20197A YU20197A YU20197A YU20197A YU 20197 A YU20197 A YU 20197A YU 20197 A YU20197 A YU 20197A YU 20197 A YU20197 A YU 20197A YU 20197 A YU20197 A YU 20197A
Authority
YU
Yugoslavia
Prior art keywords
pharmaceutical compositions
vitamine
analogues
production
active matter
Prior art date
Application number
YU20197A
Other languages
English (en)
Inventor
David Andrew Batcho
Findlay Graeme Bryce
Michael Bernard Hennessy
Anthony Jerome Lacobelli
Radoje Milan Uskoković
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Publication of YU20197A publication Critical patent/YU20197A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Opisana su jedinjenja formule I u kojoj R je vodonik, fluor, ili hidroksi, R2 je vodonik, niži alkil ili halogen, X je =CH2 ili kada je R hidroksi, X je (H, H) ili =CH2, i koja se upotrebljavaju u tretiranju hiperproliferativnih kožnih oštećenja, neoplastičnih bolesti, bolesti lojnih žlezdi, i stanja koja se u vezi sa foto oštećenjima kože.
YU20197A 1996-05-23 1997-05-20 Analozi vitamina d3, farmaceutske kompozicije koje ih sadrže kao aktivnu materiju i njihova upotreba u proizvodnji farmaceutskih kompozicija YU20197A (sh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1818696P 1996-05-23 1996-05-23
US1815396P 1996-05-23 1996-05-23
US3990097P 1997-03-19 1997-03-19

Publications (1)

Publication Number Publication Date
YU20197A true YU20197A (sh) 1999-09-27

Family

ID=27360973

Family Applications (1)

Application Number Title Priority Date Filing Date
YU20197A YU20197A (sh) 1996-05-23 1997-05-20 Analozi vitamina d3, farmaceutske kompozicije koje ih sadrže kao aktivnu materiju i njihova upotreba u proizvodnji farmaceutskih kompozicija

Country Status (29)

Country Link
EP (2) EP0808833B1 (sh)
JP (1) JP2859247B2 (sh)
KR (1) KR100783856B1 (sh)
CN (1) CN1176072C (sh)
AR (1) AR007241A1 (sh)
AT (1) ATE277008T1 (sh)
AU (1) AU723929B2 (sh)
BR (1) BR9703384A (sh)
CA (1) CA2205275C (sh)
CO (1) CO4950531A1 (sh)
CZ (1) CZ157897A3 (sh)
DE (1) DE69730774T2 (sh)
DK (1) DK0808833T3 (sh)
ES (1) ES2227635T3 (sh)
HR (1) HRP970273A2 (sh)
HU (1) HUP9700926A3 (sh)
IL (1) IL120843A0 (sh)
MA (1) MA24251A1 (sh)
NO (1) NO972304L (sh)
NZ (1) NZ314839A (sh)
PE (1) PE70198A1 (sh)
PL (1) PL320132A1 (sh)
PT (1) PT808833E (sh)
SG (1) SG70009A1 (sh)
TR (1) TR199700415A2 (sh)
TW (1) TW445252B (sh)
UY (1) UY24561A1 (sh)
YU (1) YU20197A (sh)
ZA (1) ZA974336B (sh)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
JP2002515898A (ja) * 1997-02-25 2002-05-28 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ヒトの皮膚での経時老化を防止および治療するための方法および組成物
CA2289209C (en) 1997-05-16 2006-07-25 Women & Infants Hospital Cyclic ether vitamin d3 compounds, 1.alpha. (oh) 3-epi-vitamin d3 compounds and uses thereof
EP0981514B1 (en) * 1997-05-16 2006-04-05 Woman & Infants Hospital 3-epi vitamin d2 compounds and uses thereof
EP0957098A1 (en) * 1998-05-14 1999-11-17 F. Hoffmann-La Roche Ag Intermediates for the synthesis of 3-epi vitamin D3 metabolites and analogs
US6603030B1 (en) 1999-04-22 2003-08-05 Hoffman-La Roche Inc. Process for producing phosphineoxide vitamin D precursors
HU230045B1 (hu) * 1999-04-23 2015-06-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Bőrgyógyászati alkalmazásra szolgáló nem vizes gyógyszerkészítmény
US6255501B1 (en) * 1999-04-26 2001-07-03 Hoffman-La Roche Inc. Process for preparing antiosteoporotic agents
US20020045606A1 (en) * 1999-12-02 2002-04-18 Reddy Satyanarayana G. Esters of vitamin D3 and uses thereof
GB2407499B (en) * 2003-11-03 2008-02-27 Bioxell Spa Vitamin D3 analogue for use in the treatment of BPH
CH698144B1 (fr) * 2003-09-24 2009-05-29 Bioxell Spa Analogue de la vitamine D3
SG110107A1 (en) 2003-09-24 2005-04-28 Bioxell Spa Compound and use in treatment
JP2007525533A (ja) 2004-03-01 2007-09-06 ビオエクセル エスピーエー 間質性膀胱炎の治療方法、並びに関連化合物及び組成物
US20080293647A1 (en) 2004-11-12 2008-11-27 Luciano Adorini Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
EP1883626B1 (en) * 2005-04-25 2017-10-11 OPKO Ireland Global Holdings, Ltd. Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3
JP2009508813A (ja) * 2005-08-18 2009-03-05 ビオクセル エッセ ピ ア １α−フルオロー２５−ヒドロキシ−１６−２３Ｅ−ジエン−２６，２７−ビスホモ−２０−エピ−コレカルシフェロールの合成
CA2676512A1 (en) * 2007-01-25 2008-07-31 Bioxell S.P.A. Synthesis of 1.alpha.-fluoro-25-hydroxy-16-23e-diene-26,27-bishomo-20-epi-cholecalciferol
CA2688083C (en) 2007-05-30 2015-07-07 Cytochroma Inc. Process for producing phosphine oxide vitamin d precursors
ES2366077B2 (es) * 2010-03-30 2012-06-25 Universidade De Vigo Compuestos quirales, procedimientos de obtención y uso.
US9006220B2 (en) * 2010-10-25 2015-04-14 Teijin Pharma Limited 23-yne-vitamin D3 derivative
CN105348164B (zh) * 2015-10-29 2017-03-29 无锡福祈制药有限公司 一种1α‑羟基维生素D2的制备方法
CN106748942B (zh) * 2016-11-28 2018-06-29 无锡福祈制药有限公司 度骨化醇类似物wxfq-65及其合成方法
ES2731558B2 (es) * 2018-05-15 2020-03-18 Univ Santiago Compostela Compuestos de interés farmacéutico
CN109738252B (zh) * 2019-01-23 2021-03-09 深圳天辰医疗科技有限公司 25-羟基-维生素d解离液
CN109696435B (zh) * 2019-01-25 2021-03-09 深圳天辰医疗科技有限公司 维生素d的测定方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA8923B (en) * 1988-01-20 1989-09-27 Hoffmann La Roche 16-dehydro-vitamin d3-derivatives
GB8914963D0 (en) * 1989-06-29 1989-08-23 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
DE69304279T2 (de) * 1992-05-20 1997-02-20 Hoffmann La Roche Fluorierte Analoge Vitamins D3
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
JP3228488B2 (ja) * 1993-12-24 2001-11-12 株式会社クラレ ２０−エピステロイド誘導体およびその製造方法

Also Published As

Publication number Publication date
TR199700415A3 (tr) 1997-12-21
ZA974336B (en) 1997-11-24
AU723929B2 (en) 2000-09-07
SG70009A1 (en) 2000-01-25
MX9703774A (es) 1998-06-30
KR970074765A (ko) 1997-12-10
EP1464640A3 (en) 2005-01-12
PT808833E (pt) 2004-11-30
JPH1045713A (ja) 1998-02-17
PE70198A1 (es) 1998-11-26
BR9703384A (pt) 1998-09-15
HUP9700926A3 (en) 1999-05-28
KR100783856B1 (ko) 2008-05-09
UY24561A1 (es) 2000-12-29
EP0808833A3 (en) 1998-11-25
EP0808833B1 (en) 2004-09-22
ATE277008T1 (de) 2004-10-15
CN1175573A (zh) 1998-03-11
DK0808833T3 (da) 2005-01-31
DE69730774D1 (de) 2004-10-28
DE69730774T2 (de) 2005-09-29
AU2357797A (en) 1997-11-27
CZ157897A3 (en) 1997-12-17
NO972304D0 (no) 1997-05-21
TW445252B (en) 2001-07-11
HUP9700926A2 (hu) 1998-01-28
CA2205275A1 (en) 1997-11-23
HRP970273A2 (en) 1998-04-30
ES2227635T3 (es) 2005-04-01
NZ314839A (en) 2000-01-28
MA24251A1 (fr) 1998-04-01
PL320132A1 (en) 1997-11-24
HU9700926D0 (en) 1997-07-28
EP0808833A2 (en) 1997-11-26
JP2859247B2 (ja) 1999-02-17
CN1176072C (zh) 2004-11-17
IL120843A0 (en) 1997-09-30
AR007241A1 (es) 1999-10-27
CO4950531A1 (es) 2000-09-01
EP1464640A2 (en) 2004-10-06
CA2205275C (en) 2007-04-03
TR199700415A2 (xx) 1997-12-21
NO972304L (no) 1997-11-24

Similar Documents

Publication Publication Date Title
YU20197A (sh) Analozi vitamina d3, farmaceutske kompozicije koje ih sadrže kao aktivnu materiju i njihova upotreba u proizvodnji farmaceutskih kompozicija
YU47204B (sh) Derivati didehidro-vitamina d3
LU91223I2 (fr) Ivabradine et ses dérivés pharmaceutiquement acceptables (procoralan)
NZ191867A (en) N1,n1,2,3,4,5,6-substituted-1-piperazine-carboxamides and carbothioamides
FI940696A0 (fi) Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttö
YU19997A (sh) Analozi fluorovanog vitamina d3
ATE96822T1 (de) Benzotriazolgruppenhaltiges diorganopolysiloxan.
ATE88699T1 (de) Oxidierte diphenylheteroalkane, ihre herstellung und verwendung.
ES2184774T3 (es) Bifenil-2,2'-diil-bis-difenilfosfinas halogenadas, su preparacion y empleo.
AU541413B2 (en) 2-(1,4-benzodioxan-2-ylalicyl)imidazoles
ATE1625T1 (de) Isoxazolylcarbonsaeureanilide, ihre herstellung, diese enthaltende fungizide mittel und verfahren zur bekaempfung von pilzen.
FR2429201A1 (fr) Sulfoxydes utilisables comme agents initiateurs de photopolymerisation
FI73982B (fi) Foerfarande foer framstaellning av som anxiolitiska, hypnotiska och antiepileptiska medel anvaendbara, i 2-position med en hydroxiaminogrupp substituerade 6-klor-4-fenyl- kinazolinderivat.
ATE40349T1 (de) Difluorcyclopropanderivate, verfahren zu ihrer herstellung sowie schaedlingsbekaempfungsmittel enthaltend diese verbindungen.
AU6469180A (en) 2-phenylamino-imidazolines-(2)
NO164352C (no) Analogifremgangsmaate for fremstilling av farmasoeytisk aktive, antivirale, substituerte isoksazolderivater.
DE3268605D1 (en) 3,7a-diazacyclohepta(j,k)fluorene derivatives, their preparation and therapeutical use
DK428087A (da) Dihydropyridin-5-phosphonsyre-cyclopropylenester
AU519287B2 (en) Imidazo(1,2-alpha) imidazole derivatives
IT1175915B (it) Preparati farmaceutici ad azione analgesica contenenti 5 fenil-1, 4-benzodiazepine
ATE9892T1 (de) Dibenzocycloheptenylidene und ihre verwendung in pharmazeutischen zusammensetzungen.
DE69614552D1 (de) MODIFIZIERTE ALPHA-D-GLCP-(1,2)-ALPHA-D-Glcp-(1,3)-ALPHA-D-Glcp-ANALOGE
ATE1606T1 (de) Indanyloxaminsaeure-derivate, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.