ZA8923B - 16-dehydro-vitamin d3-derivatives - Google Patents

16-dehydro-vitamin d3-derivatives

Info

Publication number
ZA8923B
ZA8923B ZA8923A ZA8923A ZA8923B ZA 8923 B ZA8923 B ZA 8923B ZA 8923 A ZA8923 A ZA 8923A ZA 8923 A ZA8923 A ZA 8923A ZA 8923 B ZA8923 B ZA 8923B
Authority
ZA
South Africa
Prior art keywords
dehydro
vitamin
derivatives
Prior art date
Application number
ZA8923A
Inventor
Enrico Giuseppe Baggiolini
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA8923B publication Critical patent/ZA8923B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
ZA8923A 1988-01-20 1989-01-03 16-dehydro-vitamin d3-derivatives ZA8923B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20

Publications (1)

Publication Number Publication Date
ZA8923B true ZA8923B (en) 1989-09-27

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8923A ZA8923B (en) 1988-01-20 1989-01-03 16-dehydro-vitamin d3-derivatives

Country Status (23)

Country Link
EP (1) EP0325279B1 (en)
JP (1) JPH0764806B2 (en)
KR (1) KR960009119B1 (en)
AR (1) AR247551A1 (en)
AT (1) ATE74350T1 (en)
AU (1) AU622139B2 (en)
BG (1) BG60530B2 (en)
CA (1) CA1337529C (en)
DE (1) DE58901056D1 (en)
DK (1) DK169945B1 (en)
ES (1) ES2033467T3 (en)
FI (1) FI90764C (en)
GR (1) GR3004786T3 (en)
HU (1) HU201007B (en)
IE (1) IE60921B1 (en)
IL (1) IL88989A (en)
MC (1) MC1998A1 (en)
NO (1) NO175429C (en)
NZ (1) NZ227641A (en)
PH (1) PH25605A (en)
PT (1) PT89486B (en)
YU (1) YU47298B (en)
ZA (1) ZA8923B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DK0398217T3 (en) * 1989-05-18 1994-02-14 Hoffmann La Roche Dehydrocholecalciferol derivatives
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DE69304279T2 (en) * 1992-05-20 1997-02-20 Hoffmann La Roche Fluorinated Analogs of Vitamins D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (en) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
ES2196476T3 (en) * 1997-05-02 2003-12-16 Duphar Int Res A METHOD OF PREPARING COMPOUNDS OF 16-DEHYDRO-VITAMIN D.
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
US9221753B2 (en) * 2004-02-03 2015-12-29 Chugai Seiyaku Kabushiki Kaisha Process for the synthesis of vitamin D compounds and intermediates for the synthesis of the compounds
EP1883626B1 (en) * 2005-04-25 2017-10-11 OPKO Ireland Global Holdings, Ltd. Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3
JP2009508813A (en) * 2005-08-18 2009-03-05 ビオクセル エッセ ピ ア Synthesis of 1α-fluoro-25-hydroxy-16-23E-diene-26,27-bishomo-20-epi-cholecalciferol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7803154A (en) * 1977-03-24 1978-09-26 Wisconsin Alumni Res Found VITAMIN D ANTAGONISTS, METHOD OF PREPARATION THEREOF, AND PREPARATIONS CONTAINING THEY.
NL7903929A (en) * 1978-05-19 1979-11-21 Wisconsin Alumni Res Found COMPOUNDS WITH ANTI-VITAMIN D ACTIVITY, PHARMACEUTICAL PREPARATION CONTAINING SUCH COMPOUND, AND METHOD OF USING SUCH COMPOUNDS.
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DK0398217T3 (en) * 1989-05-18 1994-02-14 Hoffmann La Roche Dehydrocholecalciferol derivatives

Also Published As

Publication number Publication date
NO175429B (en) 1994-07-04
DK169945B1 (en) 1995-04-10
AR247551A1 (en) 1995-01-31
BG60530B2 (en) 1995-07-28
GR3004786T3 (en) 1993-04-28
JPH0764806B2 (en) 1995-07-12
MC1998A1 (en) 1990-01-26
KR960009119B1 (en) 1996-07-13
PT89486A (en) 1989-10-04
YU47298B (en) 1995-01-31
DE58901056D1 (en) 1992-05-07
FI90764C (en) 1994-03-25
NO890239D0 (en) 1989-01-19
NO890239L (en) 1989-07-21
KR890011838A (en) 1989-08-22
EP0325279B1 (en) 1992-04-01
CA1337529C (en) 1995-11-07
YU11789A (en) 1991-04-30
ES2033467T3 (en) 1993-03-16
PH25605A (en) 1991-08-08
FI890283A0 (en) 1989-01-19
IL88989A (en) 1993-08-18
IE890157L (en) 1989-07-20
JPH029861A (en) 1990-01-12
ATE74350T1 (en) 1992-04-15
HU201007B (en) 1990-09-28
IL88989A0 (en) 1989-08-15
AU2864489A (en) 1989-07-20
EP0325279A1 (en) 1989-07-26
FI890283A (en) 1989-07-21
NO175429C (en) 1994-10-12
IE60921B1 (en) 1994-09-07
DK19789D0 (en) 1989-01-17
DK19789A (en) 1989-07-21
HUT49317A (en) 1989-09-28
NZ227641A (en) 1991-06-25
AU622139B2 (en) 1992-04-02
FI90764B (en) 1993-12-15
PT89486B (en) 1993-12-31

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