YU11789A - Derivatives of 16-dihydro-vitamine d(index 3) - Google Patents

Derivatives of 16-dihydro-vitamine d(index 3)

Info

Publication number
YU11789A
YU11789A YU00117/89A YU11789A YU11789A YU 11789 A YU11789 A YU 11789A YU 00117/89 A YU00117/89 A YU 00117/89A YU 11789 A YU11789 A YU 11789A YU 11789 A YU11789 A YU 11789A
Authority
YU
Yugoslavia
Prior art keywords
vitamine
dihydro
derivatives
index
Prior art date
Application number
YU00117/89A
Other versions
YU47298B (en
Inventor
E G Bsggiolini
B M Hennessy
S J Shiuey
G A Truitt
M R Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to SI8910117A priority Critical patent/SI8910117B/en
Publication of YU11789A publication Critical patent/YU11789A/en
Publication of YU47298B publication Critical patent/YU47298B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
YU11789A 1988-01-20 1989-01-19 DERIVATIVES 16-DEHIDRO-VITAMIN D3 YU47298B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI8910117A SI8910117B (en) 1988-01-20 1989-01-19 16-dehydro-d3 vitamin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20

Publications (2)

Publication Number Publication Date
YU11789A true YU11789A (en) 1991-04-30
YU47298B YU47298B (en) 1995-01-31

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
YU11789A YU47298B (en) 1988-01-20 1989-01-19 DERIVATIVES 16-DEHIDRO-VITAMIN D3

Country Status (23)

Country Link
EP (1) EP0325279B1 (en)
JP (1) JPH0764806B2 (en)
KR (1) KR960009119B1 (en)
AR (1) AR247551A1 (en)
AT (1) ATE74350T1 (en)
AU (1) AU622139B2 (en)
BG (1) BG60530B2 (en)
CA (1) CA1337529C (en)
DE (1) DE58901056D1 (en)
DK (1) DK169945B1 (en)
ES (1) ES2033467T3 (en)
FI (1) FI90764C (en)
GR (1) GR3004786T3 (en)
HU (1) HU201007B (en)
IE (1) IE60921B1 (en)
IL (1) IL88989A (en)
MC (1) MC1998A1 (en)
NO (1) NO175429C (en)
NZ (1) NZ227641A (en)
PH (1) PH25605A (en)
PT (1) PT89486B (en)
YU (1) YU47298B (en)
ZA (1) ZA8923B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69005897D1 (en) * 1989-05-18 1994-02-24 Hoffmann La Roche Dehydrocholecalciferol derivatives.
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
ES2091515T3 (en) * 1992-05-20 1996-11-01 Hoffmann La Roche FLUORATED ANALOGS OF VITAMIN D3.
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
TW267161B (en) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
ATE237586T1 (en) * 1997-05-02 2003-05-15 Duphar Int Res METHOD FOR PRODUCING 16-DEHYDRO VITAMIN D COMPOUNDS
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
JP4795023B2 (en) * 2004-02-03 2011-10-19 中外製薬株式会社 Method for synthesizing vitamin D compounds and synthetic intermediates thereof
JP5449767B2 (en) * 2005-04-25 2014-03-19 サイトクロマ インコーポレイテッド Low plasma calcium-elevating 16,23-diene-25-oxime analog of 1α, 25-dihydroxyvitamin D3
KR20080050420A (en) * 2005-08-18 2008-06-05 비옥셀 에스.피.에이. Synthesis of 1α-Fluoro-25-hydroxy-16-23E-diene-26,27-bishomo-20-epi-cholecalciferol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2812741C2 (en) * 1977-03-24 1987-03-12 Wisconsin Alumni Research Foundation, Madison, Wis. Vitamin D↓3↓ derivatives, processes and intermediates for their preparation and medicinal products containing them
FR2426044A2 (en) * 1978-05-19 1979-12-14 Wisconsin Research Foundation VITAMIN D3 DERIVATIVES WITH ANTI-VITAMIN D ACTIVITY
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69005897D1 (en) * 1989-05-18 1994-02-24 Hoffmann La Roche Dehydrocholecalciferol derivatives.

Also Published As

Publication number Publication date
JPH029861A (en) 1990-01-12
IE890157L (en) 1989-07-20
NO890239D0 (en) 1989-01-19
FI890283A7 (en) 1989-07-21
AR247551A1 (en) 1995-01-31
BG60530B2 (en) 1995-07-28
JPH0764806B2 (en) 1995-07-12
ZA8923B (en) 1989-09-27
YU47298B (en) 1995-01-31
DK169945B1 (en) 1995-04-10
EP0325279A1 (en) 1989-07-26
FI90764B (en) 1993-12-15
AU2864489A (en) 1989-07-20
PT89486A (en) 1989-10-04
HU201007B (en) 1990-09-28
FI890283A0 (en) 1989-01-19
AU622139B2 (en) 1992-04-02
NO175429C (en) 1994-10-12
IE60921B1 (en) 1994-09-07
NO175429B (en) 1994-07-04
PH25605A (en) 1991-08-08
GR3004786T3 (en) 1993-04-28
MC1998A1 (en) 1990-01-26
NO890239L (en) 1989-07-21
ES2033467T3 (en) 1993-03-16
DE58901056D1 (en) 1992-05-07
IL88989A (en) 1993-08-18
KR960009119B1 (en) 1996-07-13
ATE74350T1 (en) 1992-04-15
DK19789A (en) 1989-07-21
IL88989A0 (en) 1989-08-15
FI90764C (en) 1994-03-25
CA1337529C (en) 1995-11-07
PT89486B (en) 1993-12-31
DK19789D0 (en) 1989-01-17
EP0325279B1 (en) 1992-04-01
KR890011838A (en) 1989-08-22
NZ227641A (en) 1991-06-25
HUT49317A (en) 1989-09-28

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