AU2864489A - 16-dehydro-vitamin d3-derivatives - Google Patents

16-dehydro-vitamin d3-derivatives

Info

Publication number
AU2864489A
AU2864489A AU28644/89A AU2864489A AU2864489A AU 2864489 A AU2864489 A AU 2864489A AU 28644/89 A AU28644/89 A AU 28644/89A AU 2864489 A AU2864489 A AU 2864489A AU 2864489 A AU2864489 A AU 2864489A
Authority
AU
Australia
Prior art keywords
dehydro
vitamin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU28644/89A
Other versions
AU622139B2 (en
Inventor
Enrico Guiseppe Baggiolini
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU2864489A publication Critical patent/AU2864489A/en
Application granted granted Critical
Publication of AU622139B2 publication Critical patent/AU622139B2/en
Assigned to F. HOFFMANN-LA ROCHE AG reassignment F. HOFFMANN-LA ROCHE AG Alteration of Name(s) in Register under S187 Assignors: F. HOFFMANN-LA ROCHE AG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
AU28644/89A 1988-01-20 1989-01-19 16-dehydro-vitamin d3-derivatives Ceased AU622139B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20
US145932 1988-01-20

Publications (2)

Publication Number Publication Date
AU2864489A true AU2864489A (en) 1989-07-20
AU622139B2 AU622139B2 (en) 1992-04-02

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28644/89A Ceased AU622139B2 (en) 1988-01-20 1989-01-19 16-dehydro-vitamin d3-derivatives

Country Status (23)

Country Link
EP (1) EP0325279B1 (en)
JP (1) JPH0764806B2 (en)
KR (1) KR960009119B1 (en)
AR (1) AR247551A1 (en)
AT (1) ATE74350T1 (en)
AU (1) AU622139B2 (en)
BG (1) BG60530B2 (en)
CA (1) CA1337529C (en)
DE (1) DE58901056D1 (en)
DK (1) DK169945B1 (en)
ES (1) ES2033467T3 (en)
FI (1) FI90764C (en)
GR (1) GR3004786T3 (en)
HU (1) HU201007B (en)
IE (1) IE60921B1 (en)
IL (1) IL88989A (en)
MC (1) MC1998A1 (en)
NO (1) NO175429C (en)
NZ (1) NZ227641A (en)
PH (1) PH25605A (en)
PT (1) PT89486B (en)
YU (1) YU47298B (en)
ZA (1) ZA8923B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621851B2 (en) * 1988-01-20 1992-03-26 F. Hoffmann-La Roche Ag Didehydro vitamin d3 derivatives
AU669222B2 (en) * 1992-11-20 1996-05-30 F. Hoffmann-La Roche Ag Vitamin D3 analogs

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE99942T1 (en) * 1989-05-18 1994-01-15 Hoffmann La Roche DEHYDROCHOLECALCIFEROL DERIVATIVES.
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DK0580968T3 (en) * 1992-05-20 1996-10-14 Hoffmann La Roche Fluorinated analogs of vitamin D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
DE69813380T2 (en) * 1997-05-02 2003-12-04 Duphar Int Res Process for the preparation of 16-dehydro vitamin D compounds
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
US9221753B2 (en) * 2004-02-03 2015-12-29 Chugai Seiyaku Kabushiki Kaisha Process for the synthesis of vitamin D compounds and intermediates for the synthesis of the compounds
JP5449767B2 (en) * 2005-04-25 2014-03-19 サイトクロマ インコーポレイテッド Low plasma calcium-elevating 16,23-diene-25-oxime analog of 1α, 25-dihydroxyvitamin D3
JP2009508813A (en) * 2005-08-18 2009-03-05 ビオクセル エッセ ピ ア Synthesis of 1α-fluoro-25-hydroxy-16-23E-diene-26,27-bishomo-20-epi-cholecalciferol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574685A (en) * 1977-03-24 1980-09-10 Wisconsin Alumni Res Found Vitamin d3 derivatives
DE2920092A1 (en) * 1978-05-19 1979-11-29 Wisconsin Alumni Res Found ANTIVITAMIN D COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
ATE99942T1 (en) * 1989-05-18 1994-01-15 Hoffmann La Roche DEHYDROCHOLECALCIFEROL DERIVATIVES.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621851B2 (en) * 1988-01-20 1992-03-26 F. Hoffmann-La Roche Ag Didehydro vitamin d3 derivatives
AU669222B2 (en) * 1992-11-20 1996-05-30 F. Hoffmann-La Roche Ag Vitamin D3 analogs

Also Published As

Publication number Publication date
NZ227641A (en) 1991-06-25
PT89486A (en) 1989-10-04
DK19789D0 (en) 1989-01-17
BG60530B2 (en) 1995-07-28
PH25605A (en) 1991-08-08
GR3004786T3 (en) 1993-04-28
KR960009119B1 (en) 1996-07-13
NO175429B (en) 1994-07-04
NO175429C (en) 1994-10-12
HUT49317A (en) 1989-09-28
NO890239L (en) 1989-07-21
YU11789A (en) 1991-04-30
ATE74350T1 (en) 1992-04-15
KR890011838A (en) 1989-08-22
FI890283A (en) 1989-07-21
MC1998A1 (en) 1990-01-26
IE60921B1 (en) 1994-09-07
IL88989A0 (en) 1989-08-15
AU622139B2 (en) 1992-04-02
YU47298B (en) 1995-01-31
IL88989A (en) 1993-08-18
EP0325279B1 (en) 1992-04-01
FI90764B (en) 1993-12-15
IE890157L (en) 1989-07-20
JPH029861A (en) 1990-01-12
JPH0764806B2 (en) 1995-07-12
EP0325279A1 (en) 1989-07-26
DK19789A (en) 1989-07-21
HU201007B (en) 1990-09-28
ES2033467T3 (en) 1993-03-16
FI890283A0 (en) 1989-01-19
DK169945B1 (en) 1995-04-10
FI90764C (en) 1994-03-25
PT89486B (en) 1993-12-31
ZA8923B (en) 1989-09-27
NO890239D0 (en) 1989-01-19
CA1337529C (en) 1995-11-07
DE58901056D1 (en) 1992-05-07
AR247551A1 (en) 1995-01-31

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