PE70198A1 - Analogos de vitamina d3 - Google Patents
Analogos de vitamina d3Info
- Publication number
- PE70198A1 PE70198A1 PE1997000398A PE00039897A PE70198A1 PE 70198 A1 PE70198 A1 PE 70198A1 PE 1997000398 A PE1997000398 A PE 1997000398A PE 00039897 A PE00039897 A PE 00039897A PE 70198 A1 PE70198 A1 PE 70198A1
- Authority
- PE
- Peru
- Prior art keywords
- compounds
- insurance
- loss
- formula
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIEREN A COMPUESTOS DE FORMULA (I), EN DONDE: SI R ES H, F o OH; R2 ES H, ALQUILO INFERIOR O HALOGENO, DE PREFERENCIA METILO, ETILO O FLUORO; "X" ES =CH2 O CUANDO R ES OH, "X" ES (H,H) o =CH2; "A" ES -C�C-, -CH=CH- o -CH2-CH2- CON LA CONDICION DE QUE CUANDO "A" ES -CH2-CH2- R2 ES H o ALQUILO INFERIOR. TAMBIEN SE REFIERE AL PROCEDIMIENTO DE PREPARACION DE LOS COMPUESTOS DE FORMULA (I), QUE COMPRENDE DESPROTEGER COMPUESTOS CORRESPONDIENTES QUE CONTIENEN GRUPOS HIDROXI SILIL PROTEGIDOS. LOS COMPUESTOS OBTENIDOS ADEMAS DE SER UTILES EN EL TRATAMIENTO DE ENFERMEDADES DE LA PIEL HIPERPROLIFERATIVAS TAL COMO PSORIASIS, CARCINOMA DE CELULAS BASALES, TRANSTORNOS DE QUERATINIZACION Y QUERATOSIS, PROPORCIONAN EFECTOS ANTIENVEJECIMIENTO Y ANTIARRUGA, ASI COMO FAVORECEN LA RESTAURACION DE LA PIEL DANADA POR EL SOL
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1815396P | 1996-05-23 | 1996-05-23 | |
| US1818696P | 1996-05-23 | 1996-05-23 | |
| US3990097P | 1997-03-19 | 1997-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE70198A1 true PE70198A1 (es) | 1998-11-26 |
Family
ID=27360973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1997000398A PE70198A1 (es) | 1996-05-23 | 1997-05-20 | Analogos de vitamina d3 |
Country Status (29)
| Country | Link |
|---|---|
| EP (2) | EP1464640A3 (es) |
| JP (1) | JP2859247B2 (es) |
| KR (1) | KR100783856B1 (es) |
| CN (1) | CN1176072C (es) |
| AR (1) | AR007241A1 (es) |
| AT (1) | ATE277008T1 (es) |
| AU (1) | AU723929B2 (es) |
| BR (1) | BR9703384A (es) |
| CA (1) | CA2205275C (es) |
| CO (1) | CO4950531A1 (es) |
| CZ (1) | CZ157897A3 (es) |
| DE (1) | DE69730774T2 (es) |
| DK (1) | DK0808833T3 (es) |
| ES (1) | ES2227635T3 (es) |
| HR (1) | HRP970273A2 (es) |
| HU (1) | HUP9700926A3 (es) |
| IL (1) | IL120843A0 (es) |
| MA (1) | MA24251A1 (es) |
| NO (1) | NO972304L (es) |
| NZ (1) | NZ314839A (es) |
| PE (1) | PE70198A1 (es) |
| PL (1) | PL320132A1 (es) |
| PT (1) | PT808833E (es) |
| SG (1) | SG70009A1 (es) |
| TR (1) | TR199700415A2 (es) |
| TW (1) | TW445252B (es) |
| UY (1) | UY24561A1 (es) |
| YU (1) | YU20197A (es) |
| ZA (1) | ZA974336B (es) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5939408A (en) | 1996-05-23 | 1999-08-17 | Hoffman-La Roche Inc. | Vitamin D3 analogs |
| IL131543A (en) * | 1997-02-25 | 2005-08-31 | Univ Michigan | Cosmetic methods and compositions for preventing and treating chronological aging in human skin |
| AU743514B2 (en) * | 1997-05-16 | 2002-01-24 | Women & Infants Hospital | Cyclic ether vitamin D3 compounds, 1alpha (OH) 3-EPI-vitamin D3 compounds and uses thereof |
| WO1998051664A1 (en) * | 1997-05-16 | 1998-11-19 | Women & Infants Hospital | 3-epi vitamin d2 compounds and uses thereof |
| EP0957098A1 (en) * | 1998-05-14 | 1999-11-17 | F. Hoffmann-La Roche Ag | Intermediates for the synthesis of 3-epi vitamin D3 metabolites and analogs |
| US6603030B1 (en) | 1999-04-22 | 2003-08-05 | Hoffman-La Roche Inc. | Process for producing phosphineoxide vitamin D precursors |
| EP1178808B2 (en) * | 1999-04-23 | 2019-06-12 | Leo Pharma A/S | Non-aqueous pharmaceutical composition for dermal use to treat psoriasis comprising a vitamin d, a corticosteroid and a solvent component |
| US6255501B1 (en) * | 1999-04-26 | 2001-07-03 | Hoffman-La Roche Inc. | Process for preparing antiosteoporotic agents |
| AU2058701A (en) * | 1999-12-02 | 2001-06-12 | F. Hoffmann-La Roche Ag | Esters of vitamin D3 and uses thereof |
| CA2476224A1 (en) | 2003-09-24 | 2005-03-24 | Bioxell Spa | Compound and use in treatment |
| CH698144B1 (fr) * | 2003-09-24 | 2009-05-29 | Bioxell Spa | Analogue de la vitamine D3 |
| GB2407499B (en) * | 2003-11-03 | 2008-02-27 | Bioxell Spa | Vitamin D3 analogue for use in the treatment of BPH |
| US20080039434A1 (en) | 2004-03-01 | 2008-02-14 | Bioxell S. P.A. | Treatment of Interstitial Cystitis with Vitamin D Compounds |
| WO2006051106A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
| EP1883626B1 (en) * | 2005-04-25 | 2017-10-11 | OPKO Ireland Global Holdings, Ltd. | Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3 |
| CA2619311A1 (en) * | 2005-08-18 | 2007-02-22 | Bioxell S.P.A. | Synthesis of 1.alpha.-fluoro-25-hydroxy-16-23e-diene-26,27-bishomo-20-epi-cholecalciferol |
| WO2008091686A2 (en) * | 2007-01-25 | 2008-07-31 | Bioxell S.P.A. | SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL |
| CA2688083C (en) | 2007-05-30 | 2015-07-07 | Cytochroma Inc. | Process for producing phosphine oxide vitamin d precursors |
| ES2366077B2 (es) * | 2010-03-30 | 2012-06-25 | Universidade De Vigo | Compuestos quirales, procedimientos de obtención y uso. |
| JP5738307B2 (ja) * | 2010-10-25 | 2015-06-24 | 帝人ファーマ株式会社 | ２３−イン−ビタミンｄ３誘導体 |
| CN105348164B (zh) * | 2015-10-29 | 2017-03-29 | 无锡福祈制药有限公司 | 一种1α‑羟基维生素D2的制备方法 |
| CN106748942B (zh) * | 2016-11-28 | 2018-06-29 | 无锡福祈制药有限公司 | 度骨化醇类似物wxfq-65及其合成方法 |
| ES2731558B2 (es) * | 2018-05-15 | 2020-03-18 | Univ Santiago Compostela | Compuestos de interés farmacéutico |
| CN109738252B (zh) * | 2019-01-23 | 2021-03-09 | 深圳天辰医疗科技有限公司 | 25-羟基-维生素d解离液 |
| CN109696435B (zh) * | 2019-01-25 | 2021-03-09 | 深圳天辰医疗科技有限公司 | 维生素d的测定方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA8923B (en) * | 1988-01-20 | 1989-09-27 | Hoffmann La Roche | 16-dehydro-vitamin d3-derivatives |
| GB8914963D0 (en) * | 1989-06-29 | 1989-08-23 | Leo Pharm Prod Ltd | Chemical compounds |
| GB9017890D0 (en) * | 1990-08-15 | 1990-09-26 | Leo Pharm Prod Ltd | Chemical compounds i |
| GB9206648D0 (en) * | 1992-03-26 | 1992-05-06 | Leo Pharm Prod Ltd | Chemical compounds |
| DK0580968T3 (da) * | 1992-05-20 | 1996-10-14 | Hoffmann La Roche | Fluorerede analoger af vitamin D3 |
| US5428029A (en) * | 1993-11-24 | 1995-06-27 | Hoffmann-La Roche Inc. | Vitamin D3 fluorinated analogs |
| JP3228488B2 (ja) * | 1993-12-24 | 2001-11-12 | 株式会社クラレ | ２０−エピステロイド誘導体およびその製造方法 |
-
1997
- 1997-05-09 SG SG1997001439A patent/SG70009A1/en unknown
- 1997-05-13 CA CA002205275A patent/CA2205275C/en not_active Expired - Fee Related
- 1997-05-16 IL IL12084397A patent/IL120843A0/xx unknown
- 1997-05-16 NZ NZ314839A patent/NZ314839A/xx unknown
- 1997-05-19 ZA ZA9704336A patent/ZA974336B/xx unknown
- 1997-05-20 AT AT97108134T patent/ATE277008T1/de not_active IP Right Cessation
- 1997-05-20 PE PE1997000398A patent/PE70198A1/es not_active Application Discontinuation
- 1997-05-20 DE DE69730774T patent/DE69730774T2/de not_active Expired - Lifetime
- 1997-05-20 YU YU20197A patent/YU20197A/sh unknown
- 1997-05-20 ES ES97108134T patent/ES2227635T3/es not_active Expired - Lifetime
- 1997-05-20 DK DK97108134T patent/DK0808833T3/da active
- 1997-05-20 TW TW086106731A patent/TW445252B/zh not_active IP Right Cessation
- 1997-05-20 HR HR60/039,900A patent/HRP970273A2/xx not_active Application Discontinuation
- 1997-05-20 PT PT97108134T patent/PT808833E/pt unknown
- 1997-05-20 EP EP04014488A patent/EP1464640A3/en not_active Withdrawn
- 1997-05-20 EP EP97108134A patent/EP0808833B1/en not_active Expired - Lifetime
- 1997-05-21 HU HU9700926A patent/HUP9700926A3/hu unknown
- 1997-05-21 AR ARP970102158A patent/AR007241A1/es unknown
- 1997-05-21 NO NO972304A patent/NO972304L/no not_active Application Discontinuation
- 1997-05-22 JP JP9131794A patent/JP2859247B2/ja not_active Expired - Fee Related
- 1997-05-22 MA MA24635A patent/MA24251A1/fr unknown
- 1997-05-22 CO CO97028098A patent/CO4950531A1/es unknown
- 1997-05-22 CZ CZ971578A patent/CZ157897A3/cs unknown
- 1997-05-22 KR KR1019970020030A patent/KR100783856B1/ko not_active IP Right Cessation
- 1997-05-22 CN CNB971134316A patent/CN1176072C/zh not_active Expired - Fee Related
- 1997-05-22 UY UY24561A patent/UY24561A1/es unknown
- 1997-05-22 AU AU23577/97A patent/AU723929B2/en not_active Ceased
- 1997-05-22 PL PL97320132A patent/PL320132A1/xx unknown
- 1997-05-23 BR BR9703384A patent/BR9703384A/pt not_active Application Discontinuation
- 1997-05-23 TR TR97/00415A patent/TR199700415A2/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |