DK0520372T3 - Inositol-phosphat-analoger som calciumantagonistiske stoffer - Google Patents

Inositol-phosphat-analoger som calciumantagonistiske stoffer

Info

Publication number
DK0520372T3
DK0520372T3 DK92110563.1T DK92110563T DK0520372T3 DK 0520372 T3 DK0520372 T3 DK 0520372T3 DK 92110563 T DK92110563 T DK 92110563T DK 0520372 T3 DK0520372 T3 DK 0520372T3
Authority
DK
Denmark
Prior art keywords
inositol
calcium antagonists
phosphate analogues
phosphate
chem
Prior art date
Application number
DK92110563.1T
Other languages
English (en)
Inventor
Werner Dr Schiebler
Elke Deckert
Eric Dr Dreef
D Marel Geijs Dr V
Boom Jacques Prof Von
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0520372T3 publication Critical patent/DK0520372T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4081Esters with cycloaliphatic alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/117Esters of phosphoric acids with cycloaliphatic alcohols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
DK92110563.1T 1991-06-26 1992-06-23 Inositol-phosphat-analoger som calciumantagonistiske stoffer DK0520372T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91110546 1991-06-26

Publications (1)

Publication Number Publication Date
DK0520372T3 true DK0520372T3 (da) 1997-05-12

Family

ID=8206868

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92110563.1T DK0520372T3 (da) 1991-06-26 1992-06-23 Inositol-phosphat-analoger som calciumantagonistiske stoffer

Country Status (11)

Country Link
US (1) US5395828A (da)
EP (1) EP0520372B1 (da)
JP (1) JP3161813B2 (da)
KR (1) KR930000527A (da)
AT (1) ATE145911T1 (da)
CA (1) CA2072303A1 (da)
DE (1) DE69215588T2 (da)
DK (1) DK0520372T3 (da)
ES (1) ES2095985T3 (da)
GR (1) GR3022546T3 (da)
HU (2) HUT64081A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996000586A2 (en) * 1994-06-30 1996-01-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Methods for treating cell proliferative disorders by modulating signal transduction
US6759390B2 (en) 2000-05-12 2004-07-06 Manuel Martin-Lomas Compounds and their uses
US6939857B2 (en) 2000-05-12 2005-09-06 Rodaris Pharmaceuticals Limited Compounds and their uses
US6953781B2 (en) 2000-05-12 2005-10-11 Rodaris Pharmaceuticals Limited Compounds and their uses
US6716826B2 (en) 2000-05-12 2004-04-06 Rodaris Pharmaceuticals Limited Compounds and their uses
EP1331932B1 (en) * 2000-11-09 2007-04-04 Contrimmune Biotechnology Inc. Use of xestospongin c for treating or preventing hiv infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515722A (en) * 1982-03-30 1985-05-07 Merck & Co., Inc. Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
US4952717A (en) * 1986-03-11 1990-08-28 Mitsui Toatsu Chemicals, Incorporated Myoinositol derivatives and preparation process thereof
SE8605063D0 (sv) * 1986-11-26 1986-11-26 Matti Siren Derivatives of cyclohexane

Also Published As

Publication number Publication date
DE69215588T2 (de) 1997-05-15
US5395828A (en) 1995-03-07
HUT64081A (en) 1993-11-29
DE69215588D1 (de) 1997-01-16
HU9202103D0 (en) 1992-10-28
JPH05213975A (ja) 1993-08-24
EP0520372B1 (en) 1996-12-04
ES2095985T3 (es) 1997-03-01
JP3161813B2 (ja) 2001-04-25
ATE145911T1 (de) 1996-12-15
EP0520372A1 (en) 1992-12-30
HU211491A9 (en) 1995-11-28
GR3022546T3 (en) 1997-05-31
KR930000527A (ko) 1993-01-15
CA2072303A1 (en) 1992-12-27

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