ES2128335T3 - Derivados de imidazo(1,2-c)quinazolina como antihipertensivos y antidisuricos. - Google Patents

Derivados de imidazo(1,2-c)quinazolina como antihipertensivos y antidisuricos.

Info

Publication number
ES2128335T3
ES2128335T3 ES92118453T ES92118453T ES2128335T3 ES 2128335 T3 ES2128335 T3 ES 2128335T3 ES 92118453 T ES92118453 T ES 92118453T ES 92118453 T ES92118453 T ES 92118453T ES 2128335 T3 ES2128335 T3 ES 2128335T3
Authority
ES
Spain
Prior art keywords
dissuricts
quinazolina
hypertensives
imidazo
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92118453T
Other languages
English (en)
Inventor
Ji-Wang Chern
Guan-Yu Lu
Yue-Jun Lai
Mao-Hsiung Yen
Pao-Luh Tao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Science Council
Original Assignee
National Science Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Science Council filed Critical National Science Council
Application granted granted Critical
Publication of ES2128335T3 publication Critical patent/ES2128335T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

COMPUESTOS DE FORMULAS DONDE X ES SO O. ESTOS COMPUESTOS SON ENCONTRADOS UTILES COMO UN INGREDIENTE ACTIVO PARA EL TRATAMIENTO DE HIPERTENSION Y DISURIA.
ES92118453T 1991-08-13 1992-10-28 Derivados de imidazo(1,2-c)quinazolina como antihipertensivos y antidisuricos. Expired - Lifetime ES2128335T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/744,534 US5158953A (en) 1991-08-13 1991-08-13 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
EP92118453A EP0594883B1 (en) 1991-08-13 1992-10-28 Imidazo(1,2-c) quinazoline derivatives as antihypertensives and anti dysurics

Publications (1)

Publication Number Publication Date
ES2128335T3 true ES2128335T3 (es) 1999-05-16

Family

ID=26131150

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92118453T Expired - Lifetime ES2128335T3 (es) 1991-08-13 1992-10-28 Derivados de imidazo(1,2-c)quinazolina como antihipertensivos y antidisuricos.

Country Status (6)

Country Link
US (2) US5158953A (es)
EP (1) EP0594883B1 (es)
AT (1) ATE176233T1 (es)
DE (1) DE69228307T2 (es)
ES (1) ES2128335T3 (es)
TW (1) TW216795B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512677A (en) * 1991-08-13 1996-04-30 National Science Council 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5792767A (en) * 1995-01-27 1998-08-11 Abbott Laboratories Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists
US5932584A (en) * 1997-05-06 1999-08-03 National Science Council Optically active 2,3-dihydroimidazo(1,2-C) quinazoline derivatives, the preparation and antihypertensive use thereof
EP1075486A1 (en) * 1998-05-06 2001-02-14 Duke University Method of treating bladder and lower urinary tract syndromes
TW591029B (en) * 2002-01-04 2004-06-11 Pharmaceutical Ind Tech & Dev Antipsychotic pharmaceutical composition
WO2008041118A2 (en) 2006-10-04 2008-04-10 Pfizer Products Inc. Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists
GB2454549B (en) 2007-09-25 2009-09-23 Medical & Pharm Ind Tech & Dev Uses of 2-[piperidinyl]methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one for providing an anti-allergic effect and histamine H1 receptor antagonism effect
CN108178759B (zh) * 2018-01-05 2020-06-09 上海瑞纷医药科技有限责任公司 一种α-肾上腺素受体拮抗剂的合成方法
CN115650978A (zh) * 2022-10-16 2023-01-31 河南师范大学 一种7-烷氧基二氢咪唑并[4,5-b]哌啶-2-硫酮类化合物的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
FR2637596B1 (fr) * 1988-10-11 1992-09-04 Irceba Methyl-4 ((aryl-4 piperazinyl-1)-2 ethyl)-5 thiazole et ses derives, leur procede de preparation et les medicaments en contenant
FR2659329B1 (fr) * 1990-03-09 1994-06-03 Adir Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof

Also Published As

Publication number Publication date
EP0594883A1 (en) 1994-05-04
DE69228307T2 (de) 1999-06-02
EP0594883B1 (en) 1999-01-27
TW216795B (en) 1993-12-01
US5158953A (en) 1992-10-27
US5340814A (en) 1994-08-23
DE69228307D1 (de) 1999-03-11
ATE176233T1 (de) 1999-02-15

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