PT889044E - Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central - Google Patents

Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central

Info

Publication number
PT889044E
PT889044E PT98305119T PT98305119T PT889044E PT 889044 E PT889044 E PT 889044E PT 98305119 T PT98305119 T PT 98305119T PT 98305119 T PT98305119 T PT 98305119T PT 889044 E PT889044 E PT 889044E
Authority
PT
Portugal
Prior art keywords
useful
nervous system
central nervous
treating
perturbactions
Prior art date
Application number
PT98305119T
Other languages
English (en)
Inventor
Allen B Reitz
Alfonzo D Jordan
Pauline J Sanfilippo
Louis Fitzpatrick
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of PT889044E publication Critical patent/PT889044E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
PT98305119T 1997-06-30 1998-06-29 Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central PT889044E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/884,804 US5922731A (en) 1997-06-30 1997-06-30 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders

Publications (1)

Publication Number Publication Date
PT889044E true PT889044E (pt) 2005-01-31

Family

ID=25385433

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98305119T PT889044E (pt) 1997-06-30 1998-06-29 Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central

Country Status (12)

Country Link
US (1) US5922731A (pt)
EP (1) EP0889044B1 (pt)
JP (1) JPH11100380A (pt)
AT (1) ATE283269T1 (pt)
AU (2) AU7589298A (pt)
CA (1) CA2242261A1 (pt)
DE (1) DE69827706T2 (pt)
ES (1) ES2234076T3 (pt)
MX (1) MXPA98005355A (pt)
NZ (1) NZ330832A (pt)
PT (1) PT889044E (pt)
WO (1) WO1999000389A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029319A2 (en) * 1997-12-09 1999-06-17 Neurosearch A/S Chemical compounds for use as anxiolytic agents and a method for the identification of anxiolytic compounds
US6762294B2 (en) 1999-02-19 2004-07-13 The United States Of America As Represented By The Department Of Health And Human Services Polynucleotides encoding polymorphic human GABAA receptor α-6 subunit
EP1153130B1 (en) * 1999-02-19 2005-11-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Polymorphic human gaba a receptor alpha-6 subunit
ATE321044T1 (de) 1999-08-02 2006-04-15 Ortho Mcneil Pharm Inc C-6 ringsubstituierte pyrido(1,2- a)benzimidazolderivate zur behandlung von störungen des zentralen nervensystems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT656002E (pt) * 1992-08-19 2001-02-28 Mcneilab Inc Derivados de 3-oxo-pirido-1-(1,2a)-benzimidazolo-4-carboxilo e 4-oxo-azepino-(1,2a)-benzimidazolo-5-carboxilo utilizados no tratamento de disturbios do sistema nervoso central
US5521200A (en) * 1993-12-30 1996-05-28 Ho; Winston 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders
US5817668A (en) * 1996-10-07 1998-10-06 Ortho Pharmaceutical Corporation S-heteroatom containing alkyl substituted-3-oxo-pyrido 1,2-A!benzimidozole-4-carboxamide derivatives useful in treating central nervous system disorders

Also Published As

Publication number Publication date
US5922731A (en) 1999-07-13
AU757320B2 (en) 2003-02-13
AU7589298A (en) 1999-01-19
AU7395098A (en) 1999-01-07
DE69827706T2 (de) 2005-10-06
ATE283269T1 (de) 2004-12-15
ES2234076T3 (es) 2005-06-16
EP0889044B1 (en) 2004-11-24
NZ330832A (en) 2000-01-28
JPH11100380A (ja) 1999-04-13
EP0889044A1 (en) 1999-01-07
WO1999000389A1 (en) 1999-01-07
MXPA98005355A (es) 2004-10-28
DE69827706D1 (de) 2004-12-30
CA2242261A1 (en) 1998-12-30

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