ATE283269T1 - 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems - Google Patents

5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems

Info

Publication number
ATE283269T1
ATE283269T1 AT98305119T AT98305119T ATE283269T1 AT E283269 T1 ATE283269 T1 AT E283269T1 AT 98305119 T AT98305119 T AT 98305119T AT 98305119 T AT98305119 T AT 98305119T AT E283269 T1 ATE283269 T1 AT E283269T1
Authority
AT
Austria
Prior art keywords
treatment
nervous system
central nervous
pbi
pyrido
Prior art date
Application number
AT98305119T
Other languages
English (en)
Inventor
Allen B Reitz
Louis J Fitzpatrick
Alfonzo D Jordan
Pauline J Sanfilippo
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE283269T1 publication Critical patent/ATE283269T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
AT98305119T 1997-06-30 1998-06-29 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems ATE283269T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/884,804 US5922731A (en) 1997-06-30 1997-06-30 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders

Publications (1)

Publication Number Publication Date
ATE283269T1 true ATE283269T1 (de) 2004-12-15

Family

ID=25385433

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98305119T ATE283269T1 (de) 1997-06-30 1998-06-29 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems

Country Status (12)

Country Link
US (1) US5922731A (de)
EP (1) EP0889044B1 (de)
JP (1) JPH11100380A (de)
AT (1) ATE283269T1 (de)
AU (2) AU7589298A (de)
CA (1) CA2242261A1 (de)
DE (1) DE69827706T2 (de)
ES (1) ES2234076T3 (de)
MX (1) MXPA98005355A (de)
NZ (1) NZ330832A (de)
PT (1) PT889044E (de)
WO (1) WO1999000389A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1224499A (en) * 1997-12-09 1999-06-28 Neurosearch A/S Chemical compounds for use as anxiolytic agents and a method for the identification of anxiolytic compounds
US6762294B2 (en) 1999-02-19 2004-07-13 The United States Of America As Represented By The Department Of Health And Human Services Polynucleotides encoding polymorphic human GABAA receptor α-6 subunit
ATE310820T1 (de) * 1999-02-19 2005-12-15 Us Gov Health & Human Serv Polymorphismus im gen für die menschliche gaba a rezeptor alpha 6 untereinheit
WO2001009132A1 (en) 1999-08-02 2001-02-08 Ortho-Mcneil Pharmaceutical, Inc. C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2142700C (en) * 1992-08-19 2007-01-09 Bruce E. Maryanoff 3-oxo-pyrido(1,2-a)benzimidazole-4-carboxyl and 4-oxo-azepino(1,2-a)benzimidazole-5-carboxyl derivatives useful in treating central nervous system disorders
US5521200A (en) * 1993-12-30 1996-05-28 Ho; Winston 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders
ES2212081T3 (es) * 1996-10-07 2004-07-16 Ortho-Mcneil Pharmaceutical, Inc. Derivados de 3-oxo-pirido(1,2-a)bencimidazol-4-carboxamida que contienen 5-heteroatomos sustituidos con alquilo en el tratamiento de trastornos del sistema nervioso central.

Also Published As

Publication number Publication date
CA2242261A1 (en) 1998-12-30
US5922731A (en) 1999-07-13
ES2234076T3 (es) 2005-06-16
MXPA98005355A (es) 2004-10-28
AU757320B2 (en) 2003-02-13
DE69827706T2 (de) 2005-10-06
PT889044E (pt) 2005-01-31
AU7395098A (en) 1999-01-07
EP0889044B1 (de) 2004-11-24
NZ330832A (en) 2000-01-28
EP0889044A1 (de) 1999-01-07
AU7589298A (en) 1999-01-19
JPH11100380A (ja) 1999-04-13
DE69827706D1 (de) 2004-12-30
WO1999000389A1 (en) 1999-01-07

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