ATE283269T1 - 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems - Google Patents
5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystemsInfo
- Publication number
- ATE283269T1 ATE283269T1 AT98305119T AT98305119T ATE283269T1 AT E283269 T1 ATE283269 T1 AT E283269T1 AT 98305119 T AT98305119 T AT 98305119T AT 98305119 T AT98305119 T AT 98305119T AT E283269 T1 ATE283269 T1 AT E283269T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- nervous system
- central nervous
- pbi
- pyrido
- Prior art date
Links
- 208000015114 central nervous system disease Diseases 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/884,804 US5922731A (en) | 1997-06-30 | 1997-06-30 | 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE283269T1 true ATE283269T1 (de) | 2004-12-15 |
Family
ID=25385433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98305119T ATE283269T1 (de) | 1997-06-30 | 1998-06-29 | 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5922731A (de) |
| EP (1) | EP0889044B1 (de) |
| JP (1) | JPH11100380A (de) |
| AT (1) | ATE283269T1 (de) |
| AU (2) | AU7589298A (de) |
| CA (1) | CA2242261A1 (de) |
| DE (1) | DE69827706T2 (de) |
| ES (1) | ES2234076T3 (de) |
| MX (1) | MXPA98005355A (de) |
| NZ (1) | NZ330832A (de) |
| PT (1) | PT889044E (de) |
| WO (1) | WO1999000389A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1224499A (en) * | 1997-12-09 | 1999-06-28 | Neurosearch A/S | Chemical compounds for use as anxiolytic agents and a method for the identification of anxiolytic compounds |
| ES2254157T3 (es) * | 1999-02-19 | 2006-06-16 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Subunidad alfa-6 del receptor poliformico humano gabaa. |
| US6762294B2 (en) | 1999-02-19 | 2004-07-13 | The United States Of America As Represented By The Department Of Health And Human Services | Polynucleotides encoding polymorphic human GABAA receptor α-6 subunit |
| JP2003506373A (ja) * | 1999-08-02 | 2003-02-18 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 中枢神経系疾患の治療で有用なＣ−６環置換ピリド［１，２−ａ］ベンズイミダゾール誘導体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3463935B2 (ja) * | 1992-08-19 | 2003-11-05 | マクニーラブ・インコーポレーテツド | 中枢神経系障害の処置において有用な３−オキソ−ピリド（１，２−▲ａ▼）ベンズイミダゾール−４−カルボキシル及び４−オキソ−アゼピノ（１，２−▲ａ▼）ベンズイミダゾール−５−カルボキシル誘導体 |
| US5521200A (en) * | 1993-12-30 | 1996-05-28 | Ho; Winston | 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders |
| AU719333B2 (en) * | 1996-10-07 | 2000-05-04 | Ortho-Mcneil Pharmaceutical, Inc. | 5-heteroatom-containing alkyl substituted-3-oxo-p yrido(1,2-a) benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders |
-
1997
- 1997-06-30 US US08/884,804 patent/US5922731A/en not_active Expired - Lifetime
-
1998
- 1998-05-19 WO PCT/US1998/010456 patent/WO1999000389A1/en not_active Ceased
- 1998-05-19 AU AU75892/98A patent/AU7589298A/en not_active Abandoned
- 1998-06-29 ES ES98305119T patent/ES2234076T3/es not_active Expired - Lifetime
- 1998-06-29 AT AT98305119T patent/ATE283269T1/de not_active IP Right Cessation
- 1998-06-29 JP JP10196485A patent/JPH11100380A/ja active Pending
- 1998-06-29 NZ NZ330832A patent/NZ330832A/xx unknown
- 1998-06-29 PT PT98305119T patent/PT889044E/pt unknown
- 1998-06-29 DE DE69827706T patent/DE69827706T2/de not_active Expired - Fee Related
- 1998-06-29 EP EP98305119A patent/EP0889044B1/de not_active Expired - Lifetime
- 1998-06-30 AU AU73950/98A patent/AU757320B2/en not_active Ceased
- 1998-06-30 CA CA002242261A patent/CA2242261A1/en not_active Abandoned
- 1998-06-30 MX MXPA98005355A patent/MXPA98005355A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7395098A (en) | 1999-01-07 |
| MXPA98005355A (es) | 2004-10-28 |
| DE69827706T2 (de) | 2005-10-06 |
| AU757320B2 (en) | 2003-02-13 |
| JPH11100380A (ja) | 1999-04-13 |
| AU7589298A (en) | 1999-01-19 |
| CA2242261A1 (en) | 1998-12-30 |
| US5922731A (en) | 1999-07-13 |
| ES2234076T3 (es) | 2005-06-16 |
| PT889044E (pt) | 2005-01-31 |
| NZ330832A (en) | 2000-01-28 |
| EP0889044B1 (de) | 2004-11-24 |
| EP0889044A1 (de) | 1999-01-07 |
| DE69827706D1 (de) | 2004-12-30 |
| WO1999000389A1 (en) | 1999-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |