JP5249513B2 - 緑内障治療装置 - Google Patents
緑内障治療装置 Download PDFInfo
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- JP5249513B2 JP5249513B2 JP2006522665A JP2006522665A JP5249513B2 JP 5249513 B2 JP5249513 B2 JP 5249513B2 JP 2006522665 A JP2006522665 A JP 2006522665A JP 2006522665 A JP2006522665 A JP 2006522665A JP 5249513 B2 JP5249513 B2 JP 5249513B2
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- stent
- eye
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- schlemm
- canal
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/634,213 US7867186B2 (en) | 2002-04-08 | 2003-08-05 | Devices and methods for treatment of ocular disorders |
| US10/634,213 | 2003-08-05 | ||
| PCT/US2004/024988 WO2005016418A1 (en) | 2003-08-05 | 2004-08-03 | Devices and methods for glaucoma treatment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012198134A Division JP5698198B2 (ja) | 2003-08-05 | 2012-09-10 | 緑内障治療装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007501066A JP2007501066A (ja) | 2007-01-25 |
| JP2007501066A5 JP2007501066A5 (https=) | 2009-10-22 |
| JP5249513B2 true JP5249513B2 (ja) | 2013-07-31 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006522665A Expired - Fee Related JP5249513B2 (ja) | 2003-08-05 | 2004-08-03 | 緑内障治療装置 |
| JP2012198134A Expired - Lifetime JP5698198B2 (ja) | 2003-08-05 | 2012-09-10 | 緑内障治療装置 |
| JP2014080525A Expired - Lifetime JP5886354B2 (ja) | 2003-08-05 | 2014-04-09 | 緑内障治療装置 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012198134A Expired - Lifetime JP5698198B2 (ja) | 2003-08-05 | 2012-09-10 | 緑内障治療装置 |
| JP2014080525A Expired - Lifetime JP5886354B2 (ja) | 2003-08-05 | 2014-04-09 | 緑内障治療装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (8) | US7867186B2 (https=) |
| EP (2) | EP2351589B1 (https=) |
| JP (3) | JP5249513B2 (https=) |
| AU (1) | AU2004264913B2 (https=) |
| CA (1) | CA2530234C (https=) |
| ES (2) | ES2445717T3 (https=) |
| WO (1) | WO2005016418A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015171553A (ja) * | 2009-05-18 | 2015-10-01 | ドーズ メディカル コーポレーションＤｏｓｅ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ | 薬剤溶出眼内インプラント |
Families Citing this family (302)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8313454B2 (en) | 1997-11-20 | 2012-11-20 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
| AU767526B2 (en) * | 1999-04-26 | 2003-11-13 | Gmp Vision Solutions, Inc. | Trabeculotomy device and method for treating glaucoma |
| US20050119737A1 (en) * | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
| US7867186B2 (en) * | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
| US20050277864A1 (en) * | 2000-04-14 | 2005-12-15 | David Haffner | Injectable gel implant for glaucoma treatment |
| US6638239B1 (en) * | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
| US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
| US20040111050A1 (en) * | 2000-04-14 | 2004-06-10 | Gregory Smedley | Implantable ocular pump to reduce intraocular pressure |
| US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
| AU2002258754B2 (en) | 2001-04-07 | 2006-08-17 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| US6981958B1 (en) * | 2001-05-02 | 2006-01-03 | Glaukos Corporation | Implant with pressure sensor for glaucoma treatment |
| US7488303B1 (en) | 2002-09-21 | 2009-02-10 | Glaukos Corporation | Ocular implant with anchor and multiple openings |
| US7678065B2 (en) | 2001-05-02 | 2010-03-16 | Glaukos Corporation | Implant with intraocular pressure sensor for glaucoma treatment |
| WO2002089699A2 (en) | 2001-05-03 | 2002-11-14 | Glaukos Corporation | Medical device and methods of use for glaucoma treatment |
| US7331984B2 (en) * | 2001-08-28 | 2008-02-19 | Glaukos Corporation | Glaucoma stent for treating glaucoma and methods of use |
| US7186232B1 (en) | 2002-03-07 | 2007-03-06 | Glaukoa Corporation | Fluid infusion methods for glaucoma treatment |
| US7951155B2 (en) | 2002-03-15 | 2011-05-31 | Glaukos Corporation | Combined treatment for cataract and glaucoma treatment |
| US20040147870A1 (en) * | 2002-04-08 | 2004-07-29 | Burns Thomas W. | Glaucoma treatment kit |
| US9301875B2 (en) * | 2002-04-08 | 2016-04-05 | Glaukos Corporation | Ocular disorder treatment implants with multiple opening |
| US20040024345A1 (en) * | 2002-04-19 | 2004-02-05 | Morteza Gharib | Glaucoma implant with valveless flow bias |
| AU2003256657A1 (en) | 2002-07-19 | 2004-02-09 | Yale University | Uveoscleral drainage device |
| EP1539066B1 (en) * | 2002-09-17 | 2012-11-07 | Iscience Surgical Corporation | Apparatus surgical bypass of aqueous humor |
| CN1774220A (zh) | 2003-02-14 | 2006-05-17 | 德普伊斯派尔公司 | 原位成型的椎间融合器械和方法 |
| US20040225250A1 (en) | 2003-05-05 | 2004-11-11 | Michael Yablonski | Internal shunt and method for treating glaucoma |
| US7291125B2 (en) | 2003-11-14 | 2007-11-06 | Transcend Medical, Inc. | Ocular pressure regulation |
| US7004965B2 (en) * | 2003-12-17 | 2006-02-28 | Yosef Gross | Implant and delivery tool therefor |
| US20050250788A1 (en) * | 2004-01-30 | 2005-11-10 | Hosheng Tu | Aqueous outflow enhancement with vasodilated aqueous cavity |
| WO2005077113A2 (en) * | 2004-02-10 | 2005-08-25 | Quantum Orthopedics | System and method for protecting neurovascular structures |
| US20060206049A1 (en) * | 2005-03-14 | 2006-09-14 | Rodgers M S | MEMS flow module with piston-type pressure regulating structure |
| US7384550B2 (en) * | 2004-02-24 | 2008-06-10 | Becton, Dickinson And Company | Glaucoma implant having MEMS filter module |
| US20060173399A1 (en) * | 2005-02-01 | 2006-08-03 | Rodgers M S | MEMS flow module with pivoting-type baffle |
| US7364564B2 (en) * | 2004-03-02 | 2008-04-29 | Becton, Dickinson And Company | Implant having MEMS flow module with movable, flow-controlling baffle |
| US20060036207A1 (en) * | 2004-02-24 | 2006-02-16 | Koonmen James P | System and method for treating glaucoma |
| US7544176B2 (en) * | 2005-06-21 | 2009-06-09 | Becton, Dickinson And Company | Glaucoma implant having MEMS flow module with flexing diaphragm for pressure regulation |
| US20060219627A1 (en) * | 2005-03-31 | 2006-10-05 | Rodgers M S | MEMS filter module with concentric filtering walls |
| US7226540B2 (en) * | 2004-02-24 | 2007-06-05 | Becton, Dickinson And Company | MEMS filter module |
| US7901447B2 (en) | 2004-12-29 | 2011-03-08 | Boston Scientific Scimed, Inc. | Medical devices including a metallic film and at least one filament |
| US8632580B2 (en) | 2004-12-29 | 2014-01-21 | Boston Scientific Scimed, Inc. | Flexible medical devices including metallic films |
| US8591568B2 (en) | 2004-03-02 | 2013-11-26 | Boston Scientific Scimed, Inc. | Medical devices including metallic films and methods for making same |
| US8992592B2 (en) | 2004-12-29 | 2015-03-31 | Boston Scientific Scimed, Inc. | Medical devices including metallic films |
| US8998973B2 (en) | 2004-03-02 | 2015-04-07 | Boston Scientific Scimed, Inc. | Medical devices including metallic films |
| US20050232972A1 (en) * | 2004-04-15 | 2005-10-20 | Steven Odrich | Drug delivery via punctal plug |
| ZA200609408B (en) * | 2004-04-29 | 2008-02-27 | Iscience Interventional Corp | Apparatus and method for surgical enhancement of aqueous humor drainage |
| US20100173866A1 (en) * | 2004-04-29 | 2010-07-08 | Iscience Interventional Corporation | Apparatus and method for ocular treatment |
| US20050283108A1 (en) * | 2004-06-10 | 2005-12-22 | Savage James A | Apparatus and method for non-pharmacological treatment of glaucoma and lowering intraocular pressure |
| DK1765454T3 (en) * | 2004-07-02 | 2016-05-02 | Mati Therapeutics Inc | Device for submission of treatment medium to eye |
| EP2215996B1 (en) * | 2004-12-16 | 2013-04-03 | Iscience Interventional Corporation | Ophthalmic implant for treatment of glaucoma |
| WO2006093880A1 (en) * | 2005-02-28 | 2006-09-08 | Wilson-Cook Medical Inc. | Removable coiled stent |
| US7854760B2 (en) | 2005-05-16 | 2010-12-21 | Boston Scientific Scimed, Inc. | Medical devices including metallic films |
| US8366773B2 (en) | 2005-08-16 | 2013-02-05 | Benvenue Medical, Inc. | Apparatus and method for treating bone |
| JP4944111B2 (ja) | 2005-08-16 | 2012-05-30 | ベンベニュー メディカル， インコーポレイテッド | 脊柱組織伸延装置 |
| EP2182078B1 (en) * | 2005-09-01 | 2012-02-01 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators |
| US20070106200A1 (en) * | 2005-11-08 | 2007-05-10 | Brian Levy | Intraocular shunt device and method |
| EP3838236B1 (en) | 2006-01-17 | 2025-08-13 | Alcon Inc. | Glaucoma treatment device |
| WO2007084582A2 (en) | 2006-01-17 | 2007-07-26 | Forsight Labs, Llc | Drug delivery treatment device |
| EP2004172B1 (en) | 2006-03-31 | 2019-03-13 | Mati Therapeutics Inc. | Drug delivery structures and compositions for nasolacrimal system |
| US7909789B2 (en) | 2006-06-26 | 2011-03-22 | Sight Sciences, Inc. | Intraocular implants and methods and kits therefor |
| US8308701B2 (en) | 2010-11-15 | 2012-11-13 | Aquesys, Inc. | Methods for deploying intraocular shunts |
| US8974511B2 (en) | 2010-11-15 | 2015-03-10 | Aquesys, Inc. | Methods for treating closed angle glaucoma |
| US10085884B2 (en) | 2006-06-30 | 2018-10-02 | Aquesys, Inc. | Intraocular devices |
| US8852137B2 (en) | 2010-11-15 | 2014-10-07 | Aquesys, Inc. | Methods for implanting a soft gel shunt in the suprachoroidal space |
| US20120123317A1 (en) * | 2010-11-15 | 2012-05-17 | Aquesys, Inc. | Methods for implanation of glaucoma shunts |
| US8828070B2 (en) | 2010-11-15 | 2014-09-09 | Aquesys, Inc. | Devices for deploying intraocular shunts |
| US8852256B2 (en) | 2010-11-15 | 2014-10-07 | Aquesys, Inc. | Methods for intraocular shunt placement |
| US8758290B2 (en) | 2010-11-15 | 2014-06-24 | Aquesys, Inc. | Devices and methods for implanting a shunt in the suprachoroidal space |
| US8801766B2 (en) | 2010-11-15 | 2014-08-12 | Aquesys, Inc. | Devices for deploying intraocular shunts |
| JP5396272B2 (ja) * | 2006-06-30 | 2014-01-22 | アクエシス インコーポレイテッド | 臓器内圧力軽減のための方法、システムおよび装置 |
| US9095411B2 (en) | 2010-11-15 | 2015-08-04 | Aquesys, Inc. | Devices for deploying intraocular shunts |
| US8663303B2 (en) | 2010-11-15 | 2014-03-04 | Aquesys, Inc. | Methods for deploying an intraocular shunt from a deployment device and into an eye |
| US8721702B2 (en) | 2010-11-15 | 2014-05-13 | Aquesys, Inc. | Intraocular shunt deployment devices |
| US20120123316A1 (en) | 2010-11-15 | 2012-05-17 | Aquesys, Inc. | Intraocular shunts for placement in the intra-tenon's space |
| EP2374434B1 (en) * | 2006-09-06 | 2016-03-02 | Cook Medical Technologies LLC | Stents with connectors and stabilizing biodegradable elements |
| WO2008061043A2 (en) | 2006-11-10 | 2008-05-22 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
| US8105382B2 (en) | 2006-12-07 | 2012-01-31 | Interventional Spine, Inc. | Intervertebral implant |
| JP4957258B2 (ja) * | 2007-01-15 | 2012-06-20 | 富士通株式会社 | 歩数計数装置および歩数計数方法 |
| EP2124777A4 (en) | 2007-02-21 | 2013-06-05 | Benvenue Medical Inc | DEVICES FOR SPINE COLUMN TREATMENT |
| ES2757819T3 (es) | 2007-02-21 | 2020-04-30 | Benvenue Medical Inc | Dispositivos para tratar la columna vertebral |
| US20100130815A1 (en) * | 2007-05-18 | 2010-05-27 | Prostaplant Ltd. | Intraurethral and extraurethral apparatus |
| JP2010527678A (ja) * | 2007-05-23 | 2010-08-19 | オスシロン リミテッド | 慢性完全閉塞の誘導貫通のための装置及び方法 |
| US20080306429A1 (en) * | 2007-06-07 | 2008-12-11 | Shields Milton B | Uveoscleral drainage device |
| US8900307B2 (en) | 2007-06-26 | 2014-12-02 | DePuy Synthes Products, LLC | Highly lordosed fusion cage |
| WO2009012406A1 (en) * | 2007-07-17 | 2009-01-22 | Transcend Medical, Inc. | Ocular implant with hydrogel expansion capabilities reference to priority document |
| US8968396B2 (en) | 2007-07-23 | 2015-03-03 | Powervision, Inc. | Intraocular lens delivery systems and methods of use |
| CA2698508C (en) | 2007-09-07 | 2017-06-06 | Alan R. Rapacki | Lacrimal implants and related methods |
| CN102670352A (zh) * | 2007-09-07 | 2012-09-19 | Qlt股份有限公司 | 用于泪腺植入物的插入和抽出工具 |
| AU2008300013A1 (en) | 2007-09-07 | 2009-03-19 | Qlt Inc. | Drug cores for sustained release of therapeutic agents |
| NZ583858A (en) | 2007-09-07 | 2012-08-31 | Quadra Logic Tech Inc | Lacrimal implant detection with detection device |
| US20090082862A1 (en) | 2007-09-24 | 2009-03-26 | Schieber Andrew T | Ocular Implant Architectures |
| US8734377B2 (en) * | 2007-09-24 | 2014-05-27 | Ivantis, Inc. | Ocular implants with asymmetric flexibility |
| US7740604B2 (en) | 2007-09-24 | 2010-06-22 | Ivantis, Inc. | Ocular implants for placement in schlemm's canal |
| US20170360609A9 (en) | 2007-09-24 | 2017-12-21 | Ivantis, Inc. | Methods and devices for increasing aqueous humor outflow |
| WO2009057774A1 (ja) * | 2007-10-31 | 2009-05-07 | Olympus Corporation | 薬液投与システムおよび薬液投与用カニューラ |
| US8808222B2 (en) | 2007-11-20 | 2014-08-19 | Ivantis, Inc. | Methods and apparatus for delivering ocular implants into the eye |
| US8512404B2 (en) * | 2007-11-20 | 2013-08-20 | Ivantis, Inc. | Ocular implant delivery system and method |
| US8230866B2 (en) * | 2007-12-13 | 2012-07-31 | Carl Zeiss Meditec Ag | Systems and methods for treating glaucoma and systems and methods for imaging a portion of an eye |
| EP2471493A1 (en) | 2008-01-17 | 2012-07-04 | Synthes GmbH | An expandable intervertebral implant and associated method of manufacturing the same |
| EP2244759B1 (en) * | 2008-01-28 | 2024-11-27 | Implantica Patent Ltd. | A filter cleaning device |
| US8109896B2 (en) * | 2008-02-11 | 2012-02-07 | Optonol Ltd. | Devices and methods for opening fluid passageways |
| SG188155A1 (en) * | 2008-02-18 | 2013-03-28 | Quadra Logic Tech Inc | Lacrimal implants and related methods |
| JP2011513002A (ja) | 2008-03-05 | 2011-04-28 | イバンティス インコーポレイテッド | 緑内障を治療する方法及び器具 |
| CN102036623A (zh) | 2008-04-05 | 2011-04-27 | 斯恩蒂斯有限公司 | 可膨胀的椎间植入体 |
| WO2009134371A2 (en) | 2008-04-30 | 2009-11-05 | Qlt Plug Delivery, Inc. | Composite lacrimal insert and related methods |
| CN102123713A (zh) * | 2008-05-09 | 2011-07-13 | Qlt栓塞输送公司 | 治疗青光眼和眼高血压的活性剂的持续释放递送 |
| US8157759B2 (en) * | 2008-05-16 | 2012-04-17 | Ocumatrix, Inc. | Method and apparatus for fluid drainage of the eye |
| EP2334268B1 (en) * | 2008-06-25 | 2017-08-02 | Novartis Ag | Ocular implant with shape change capabilities |
| US8945142B2 (en) * | 2008-08-27 | 2015-02-03 | Cook Medical Technologies Llc | Delivery system for implanting nasal ventilation tube |
| US20100125323A1 (en) * | 2008-11-14 | 2010-05-20 | Medtronic Vascular, Inc. | Coil Stent Delivery System and Method of Use |
| JP5520962B2 (ja) | 2008-12-05 | 2014-06-11 | イバンティス インコーポレイテッド | 眼内インプラントを眼球内に送出するための装置 |
| US20100191177A1 (en) * | 2009-01-23 | 2010-07-29 | Iscience Interventional Corporation | Device for aspirating fluids |
| US8425473B2 (en) * | 2009-01-23 | 2013-04-23 | Iscience Interventional Corporation | Subretinal access device |
| ES2817775T3 (es) * | 2009-01-28 | 2021-04-08 | Alcon Inc | Implante ocular con calidades de rigidez |
| US20100191168A1 (en) | 2009-01-29 | 2010-07-29 | Trustees Of Tufts College | Endovascular cerebrospinal fluid shunt |
| KR20110132369A (ko) * | 2009-02-23 | 2011-12-07 | 큐엘티 인코포레이티드 | 눈물 임플란트 및 관련 방법 |
| US8535327B2 (en) | 2009-03-17 | 2013-09-17 | Benvenue Medical, Inc. | Delivery apparatus for use with implantable medical devices |
| WO2010111140A2 (en) | 2009-03-25 | 2010-09-30 | University Of Iowa Research Foundation | Methods and devices for arytenoid repositioning |
| US20100247606A1 (en) * | 2009-03-25 | 2010-09-30 | Allergan, Inc. | Intraocular sustained release drug delivery systems and methods for treating ocular conditions |
| US9526620B2 (en) | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| US8764696B2 (en) * | 2009-06-16 | 2014-07-01 | Mobius Therapeutics, Inc. | Medical drainage devices with carbon-based structures for inhibiting growth of fibroblasts |
| JP5726186B2 (ja) * | 2009-07-09 | 2015-05-27 | イバンティス インコーポレイテッド | 眼内インプラントを送出するための単オペレータデバイス |
| AU2010271218B2 (en) | 2009-07-09 | 2017-02-02 | Alcon Inc. | Ocular implants and methods for delivering ocular implants into the eye |
| WO2011046949A2 (en) * | 2009-10-12 | 2011-04-21 | The Regents Of The University Of Colorado, A Body Corporate | Implants for reducing intraocular pressure |
| JP2013508096A (ja) | 2009-10-23 | 2013-03-07 | イバンティス インコーポレイテッド | 眼内移植システムおよび眼内移植方法 |
| US20110105990A1 (en) * | 2009-11-04 | 2011-05-05 | Silvestrini Thomas A | Zonal drug delivery device and method |
| US9393129B2 (en) | 2009-12-10 | 2016-07-19 | DePuy Synthes Products, Inc. | Bellows-like expandable interbody fusion cage |
| US20120245505A1 (en) * | 2009-12-16 | 2012-09-27 | Robinson Michael R | Intracameral devices for sustained delivery |
| US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
| WO2011097408A1 (en) | 2010-02-05 | 2011-08-11 | Sight Sciences, Inc | Intraocular implants and related kits and methods |
| US8900298B2 (en) | 2010-02-23 | 2014-12-02 | Powervision, Inc. | Fluid for accommodating intraocular lenses |
| JP6377906B2 (ja) | 2010-03-19 | 2018-08-22 | アヴェドロ・インコーポレーテッドＡｖｅｄｒｏ，Ｉｎｃ． | 眼治療を適用およびモニターするためのシステム |
| US8545430B2 (en) | 2010-06-09 | 2013-10-01 | Transcend Medical, Inc. | Expandable ocular devices |
| WO2011163505A1 (en) | 2010-06-23 | 2011-12-29 | Ivantis, Inc. | Ocular implants deployed in schlemm's canal of the eye |
| US8979860B2 (en) | 2010-06-24 | 2015-03-17 | DePuy Synthes Products. LLC | Enhanced cage insertion device |
| US9282979B2 (en) | 2010-06-24 | 2016-03-15 | DePuy Synthes Products, Inc. | Instruments and methods for non-parallel disc space preparation |
| AU2011271465B2 (en) | 2010-06-29 | 2015-03-19 | Synthes Gmbh | Distractible intervertebral implant |
| US9402732B2 (en) | 2010-10-11 | 2016-08-02 | DePuy Synthes Products, Inc. | Expandable interspinous process spacer implant |
| US8585629B2 (en) | 2010-11-15 | 2013-11-19 | Aquesys, Inc. | Systems for deploying intraocular shunts |
| US10842671B2 (en) | 2010-11-15 | 2020-11-24 | Aquesys, Inc. | Intraocular shunt placement in the suprachoroidal space |
| US9668915B2 (en) | 2010-11-24 | 2017-06-06 | Dose Medical Corporation | Drug eluting ocular implant |
| CN103619366B (zh) | 2011-04-15 | 2018-02-16 | 马萨诸塞州大学 | 外科腔引流和闭合系统 |
| US20120283557A1 (en) | 2011-05-05 | 2012-11-08 | Berlin Michael S | Methods and Apparatuses for the Treatment of Glaucoma using visible and infrared ultrashort laser pulses |
| WO2012167260A2 (en) | 2011-06-02 | 2012-12-06 | Avedro, Inc. | Systems and methods for monitoring time based photo active agent delivery or photo active marker presence |
| US8657776B2 (en) | 2011-06-14 | 2014-02-25 | Ivantis, Inc. | Ocular implants for delivery into the eye |
| WO2012178018A2 (en) | 2011-06-24 | 2012-12-27 | Benvenue Medical, Inc. | Devices and methods for treating bone tissue |
| CN102949263B (zh) * | 2011-08-18 | 2014-04-09 | 杨勋 | 自疏通青光眼钉 |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| ES2727203T3 (es) | 2011-08-29 | 2019-10-14 | Mati Therapeutics Inc | Administración por liberación sostenida de agentes activos para tratar glaucoma e hipertensión ocular |
| EP3659495B1 (en) | 2011-09-13 | 2022-12-14 | Dose Medical Corporation | Intraocular physiological sensor |
| US9610195B2 (en) | 2013-02-27 | 2017-04-04 | Aquesys, Inc. | Intraocular shunt implantation methods and devices |
| US8765210B2 (en) | 2011-12-08 | 2014-07-01 | Aquesys, Inc. | Systems and methods for making gelatin shunts |
| US9808373B2 (en) | 2013-06-28 | 2017-11-07 | Aquesys, Inc. | Intraocular shunt implantation |
| US8852136B2 (en) | 2011-12-08 | 2014-10-07 | Aquesys, Inc. | Methods for placing a shunt into the intra-scleral space |
| US10080682B2 (en) * | 2011-12-08 | 2018-09-25 | Aquesys, Inc. | Intrascleral shunt placement |
| US8663150B2 (en) | 2011-12-19 | 2014-03-04 | Ivantis, Inc. | Delivering ocular implants into the eye |
| US9216109B2 (en) | 2012-03-20 | 2015-12-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US9173775B2 (en) | 2012-03-26 | 2015-11-03 | Glaukos Corporation | System for delivering multiple ocular implants |
| US9358156B2 (en) | 2012-04-18 | 2016-06-07 | Invantis, Inc. | Ocular implants for delivery into an anterior chamber of the eye |
| US10085633B2 (en) | 2012-04-19 | 2018-10-02 | Novartis Ag | Direct visualization system for glaucoma treatment |
| US9241832B2 (en) | 2012-04-24 | 2016-01-26 | Transcend Medical, Inc. | Delivery system for ocular implant |
| US8858491B2 (en) * | 2012-05-23 | 2014-10-14 | Alcon Research, Ltd. | Pre-biased membrane valve |
| US9501823B2 (en) * | 2012-08-02 | 2016-11-22 | Agency For Science, Technology And Research | Methods and systems for characterizing angle closure glaucoma for risk assessment or screening |
| US9308082B2 (en) * | 2012-08-07 | 2016-04-12 | RegenEye, L.L.C. | Ocular collar stent for treating narrowing of the irideocorneal angle |
| EP3228286A1 (en) | 2012-09-17 | 2017-10-11 | Novartis AG | Expanding ocular impant devices |
| WO2014078431A1 (en) * | 2012-11-13 | 2014-05-22 | University Of Massachusetts | Surgical cavity drainage and closure system |
| US9763829B2 (en) | 2012-11-14 | 2017-09-19 | Novartis Ag | Flow promoting ocular implant |
| US20140276361A1 (en) * | 2012-11-20 | 2014-09-18 | Avedro, Inc. | Systems and methods for treating glaucoma |
| US10617558B2 (en) | 2012-11-28 | 2020-04-14 | Ivantis, Inc. | Apparatus for delivering ocular implants into an anterior chamber of the eye |
| US10159600B2 (en) | 2013-02-19 | 2018-12-25 | Aquesys, Inc. | Adjustable intraocular flow regulation |
| US9125723B2 (en) | 2013-02-19 | 2015-09-08 | Aquesys, Inc. | Adjustable glaucoma implant |
| US9717601B2 (en) | 2013-02-28 | 2017-08-01 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
| US9522070B2 (en) | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
| US9730638B2 (en) | 2013-03-13 | 2017-08-15 | Glaukos Corporation | Intraocular physiological sensor |
| US10085783B2 (en) | 2013-03-14 | 2018-10-02 | Izi Medical Products, Llc | Devices and methods for treating bone tissue |
| US9592151B2 (en) | 2013-03-15 | 2017-03-14 | Glaukos Corporation | Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye |
| HK1219862A1 (zh) * | 2013-03-15 | 2017-04-21 | Orasis Medical, Inc. | 水流动的增强 |
| ES2834479T3 (es) | 2013-03-15 | 2021-06-17 | Alcon Inc | Método para reconfigurar una lente intraocular para su entrega a un dispositivo de entrega |
| US10517759B2 (en) | 2013-03-15 | 2019-12-31 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| US9987163B2 (en) | 2013-04-16 | 2018-06-05 | Novartis Ag | Device for dispensing intraocular substances |
| US9649223B2 (en) * | 2013-06-13 | 2017-05-16 | Innfocus, Inc. | Inserter for tubular medical implant devices |
| US9226851B2 (en) | 2013-08-24 | 2016-01-05 | Novartis Ag | MEMS check valve chip and methods |
| US9585790B2 (en) | 2013-11-14 | 2017-03-07 | Aquesys, Inc. | Intraocular shunt inserter |
| US9597009B2 (en) * | 2013-12-19 | 2017-03-21 | Novartis Ag | Marker-based tool tracking |
| US9205181B2 (en) | 2014-01-09 | 2015-12-08 | Rainbow Medical, Ltd. | Injectable hydrogel implant for treating glaucoma |
| US9737696B2 (en) | 2014-01-15 | 2017-08-22 | Tufts Medical Center, Inc. | Endovascular cerebrospinal fluid shunt |
| EP3998100A1 (en) | 2014-01-15 | 2022-05-18 | Tufts Medical Center, Inc. | Endovascular cerebrospinal fluid shunt system |
| EP3677229A1 (en) * | 2014-05-29 | 2020-07-08 | Glaukos Corporation | Implants with controlled drug delivery features |
| WO2016004223A1 (en) | 2014-07-01 | 2016-01-07 | Cao Ariel | Methods and devices for implantation of intraocular pressure sensors |
| JP2017527329A (ja) | 2014-07-01 | 2017-09-21 | インジェクトセンス， インコーポレイテッド | 垂直積層構造を備える、気密封止したインプラントセンサ |
| US10709547B2 (en) | 2014-07-14 | 2020-07-14 | Ivantis, Inc. | Ocular implant delivery system and method |
| KR102545628B1 (ko) | 2014-10-27 | 2023-06-20 | 아베드로 인코퍼레이티드 | 눈의 교차-결합 처리를 위한 시스템 및 방법 |
| WO2016070147A1 (en) | 2014-10-31 | 2016-05-06 | Cerevasc, Llc | Methods and systems for treating hydrocephalus |
| WO2016077747A1 (en) | 2014-11-13 | 2016-05-19 | Avedro, Inc. | Multipass virtually imaged phased array etalon |
| CN113230021A (zh) | 2015-01-12 | 2021-08-10 | 科达莱昂治疗公司 | 微滴递送设备和方法 |
| DE102015002729A1 (de) * | 2015-02-27 | 2016-09-01 | Carl Zeiss Meditec Ag | Ophthalmologische Lasertherapievorrichtung und Verfahren zur Erzeugung cornealer Zugangsschnitte |
| US11426290B2 (en) | 2015-03-06 | 2022-08-30 | DePuy Synthes Products, Inc. | Expandable intervertebral implant, system, kit and method |
| WO2016149425A1 (en) | 2015-03-16 | 2016-09-22 | Da Silva Curiel Jeannette M A | Method and apparatus for inserting an implant in the cornea of the eye |
| US11992436B2 (en) | 2015-03-16 | 2024-05-28 | Jeannette M. A. da Silva Curiel | Method and apparatus for inserting an implant in the cornea of the eye |
| EP3270765B1 (en) | 2015-03-20 | 2020-05-06 | Glaukos Corporation | Gonioscopic devices |
| US10299958B2 (en) | 2015-03-31 | 2019-05-28 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| JP2018515153A (ja) | 2015-04-10 | 2018-06-14 | ケダリオン セラピューティックス，インコーポレイテッド | 交換式アンプルを備えた圧電式ディスペンサ |
| EP3285704B1 (en) | 2015-04-24 | 2020-11-18 | Avedro Inc. | Systems for photoactivating a photosensitizer applied to an eye |
| US20160331584A1 (en) * | 2015-05-14 | 2016-11-17 | Novartis Ag | Surgical tool tracking to control surgical system |
| US10028657B2 (en) | 2015-05-22 | 2018-07-24 | Avedro, Inc. | Systems and methods for monitoring cross-linking activity for corneal treatments |
| KR102268628B1 (ko) | 2015-06-03 | 2021-06-24 | 아큐시스, 인코포레이티드 | 안구내 션트의 외부 배치 |
| EP3103417B1 (en) * | 2015-06-10 | 2018-01-31 | Biedermann Technologies GmbH & Co. KG | Intervertebral implant and system of an intervertebral implant and an instrument for inserting the intervertebral implant |
| EP3313335B1 (en) * | 2015-06-26 | 2021-11-10 | Innfocus, Inc. | Glaucoma device |
| KR102706856B1 (ko) | 2015-07-21 | 2024-09-19 | 아베드로 인코퍼레이티드 | 광증감제로 눈을 치료하기 위한 시스템 및 방법 |
| WO2017030917A1 (en) | 2015-08-14 | 2017-02-23 | Ivantis, Inc. | Ocular inplant with pressure sensor and delivery system |
| US11925578B2 (en) | 2015-09-02 | 2024-03-12 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
| WO2017049248A1 (en) | 2015-09-16 | 2017-03-23 | Orange County Glaucoma, Pc | Shunt for vascular flow enhancement |
| WO2017053885A1 (en) | 2015-09-25 | 2017-03-30 | Glaukos Corporation | Punctal implants with controlled drug delivery features and methods of using same |
| ES2609128B1 (es) * | 2015-10-14 | 2018-01-25 | Servicio Andaluz De Salud | Dispositivo intraocular para la protección de la retina |
| WO2017075544A1 (en) | 2015-10-30 | 2017-05-04 | Cerevasc, Llc | Systems and methods for treating hydrocephalus |
| US11938058B2 (en) | 2015-12-15 | 2024-03-26 | Alcon Inc. | Ocular implant and delivery system |
| US20190038462A1 (en) * | 2015-12-24 | 2019-02-07 | Istar Medical | Ocular Implant Systems |
| CN105434103B (zh) * | 2015-12-29 | 2017-07-07 | 北京大学人民医院 | 一种微型青光眼引流植入装置及系统 |
| EP3442479B1 (en) | 2016-04-20 | 2026-03-04 | Glaukos Corporation | Bioresorbable ocular drug delivery device |
| WO2017210627A1 (en) | 2016-06-02 | 2017-12-07 | Aquesys, Inc. | Intraocular drug delivery |
| EP3474783B1 (en) | 2016-06-28 | 2023-05-03 | Eit Emerging Implant Technologies GmbH | Expandable, angularly adjustable intervertebral cages |
| WO2018002715A2 (en) | 2016-06-28 | 2018-01-04 | Eit Emerging Implant Technologies Gmbh | Expandable and angularly adjustable articulating intervertebral cages |
| US10973585B2 (en) | 2016-09-21 | 2021-04-13 | Alcon Inc. | Systems and methods for tracking the orientation of surgical tools |
| US10291646B2 (en) * | 2016-10-03 | 2019-05-14 | Telepathy Labs, Inc. | System and method for audio fingerprinting for attack detection |
| EP3525866B1 (en) | 2016-10-11 | 2023-09-20 | CereVasc, Inc. | Methods and systems for treating hydrocephalus |
| MX2019006576A (es) | 2016-12-07 | 2019-08-21 | Mayo Found Medical Education & Res | Metodos y materiales para usar soportes de fibrina para trasplante de epitelio de pigmento retiniano. |
| US10888433B2 (en) | 2016-12-14 | 2021-01-12 | DePuy Synthes Products, Inc. | Intervertebral implant inserter and related methods |
| KR102412086B1 (ko) | 2017-01-20 | 2022-06-22 | 켄달리온 테라퓨틱스 인코포레이티드 | 압전 유체 분배기 |
| US10674906B2 (en) | 2017-02-24 | 2020-06-09 | Glaukos Corporation | Gonioscopes |
| US11523940B2 (en) | 2017-03-17 | 2022-12-13 | W. L. Gore & Associates, Inc. | Delivery aids for glaucoma shunts |
| GB201705177D0 (en) * | 2017-03-31 | 2017-05-17 | Sharma Anant | Device to aid movement of substance from the eye |
| US10398563B2 (en) | 2017-05-08 | 2019-09-03 | Medos International Sarl | Expandable cage |
| US11344424B2 (en) | 2017-06-14 | 2022-05-31 | Medos International Sarl | Expandable intervertebral implant and related methods |
| US20190117459A1 (en) * | 2017-06-16 | 2019-04-25 | Michael S. Berlin | Methods and Systems for OCT Guided Glaucoma Surgery |
| US10940016B2 (en) | 2017-07-05 | 2021-03-09 | Medos International Sarl | Expandable intervertebral fusion cage |
| KR102315263B1 (ko) * | 2017-07-19 | 2021-10-20 | 동국대학교 경주캠퍼스 산학협력단 | 나선형 다공 방수 유출장치 |
| WO2019018807A1 (en) | 2017-07-20 | 2019-01-24 | Shifamed Holdings, Llc | ADJUSTABLE FLOW GLAUCOMA DERIVATIVES AND METHODS OF MAKING AND USING SAME |
| US11166849B2 (en) | 2017-07-20 | 2021-11-09 | Shifamed Holdings, Llc | Adjustable flow glaucoma shunts and methods for making and using same |
| EP3668460A4 (en) * | 2017-08-17 | 2021-05-05 | Aspip Inc. | METHOD, DEVICE AND SYSTEM FOR TREATING HIGH INTRAOCULAR PRESSURE |
| US11116625B2 (en) | 2017-09-28 | 2021-09-14 | Glaukos Corporation | Apparatus and method for controlling placement of intraocular implants |
| AU2018338994B2 (en) | 2017-09-29 | 2024-03-28 | Glaukos Corporation | Intraocular physiological sensor |
| US11376040B2 (en) | 2017-10-06 | 2022-07-05 | Glaukos Corporation | Systems and methods for delivering multiple ocular implants |
| USD846738S1 (en) | 2017-10-27 | 2019-04-23 | Glaukos Corporation | Implant delivery apparatus |
| US11246753B2 (en) | 2017-11-08 | 2022-02-15 | Aquesys, Inc. | Manually adjustable intraocular flow regulation |
| WO2019113483A1 (en) | 2017-12-08 | 2019-06-13 | Kedalion Therapeutics, Inc. | Fluid delivery alignment system |
| US20210045917A1 (en) * | 2018-02-02 | 2021-02-18 | Rhb Research, Llc | Devices and Methods for Illuminating an Intraocular Implant |
| US12029683B2 (en) | 2018-02-22 | 2024-07-09 | Alcon Inc. | Ocular implant and delivery system |
| WO2019173784A1 (en) | 2018-03-08 | 2019-09-12 | Cerevasc, Llc | Systems and methods for minimally invasive drug delivery to a subarachnoid space |
| US10952898B2 (en) | 2018-03-09 | 2021-03-23 | Aquesys, Inc. | Intraocular shunt inserter |
| US11135089B2 (en) | 2018-03-09 | 2021-10-05 | Aquesys, Inc. | Intraocular shunt inserter |
| WO2019200121A1 (en) * | 2018-04-12 | 2019-10-17 | Kedalion Therapeutics, Inc. | Topical ocular delivery methods and devices for use in the same |
| US12350194B1 (en) | 2018-04-12 | 2025-07-08 | Bausch + Lomb Ireland Limited | Topical ocular delivery of fluids with controlled mass dosing and wireless communication |
| US20190314197A1 (en) | 2018-04-12 | 2019-10-17 | Kedalion Therapeutics, Inc. | Topical Ocular Delivery Methods and Devices for Use in the Same |
| WO2020010116A1 (en) | 2018-07-03 | 2020-01-09 | Kedalion Therapeutics, Inc. | Topical ocular delivery devices and methods for using the same |
| US20200100941A1 (en) | 2018-08-25 | 2020-04-02 | Thad Anthony Labbe | Ophthalmic surgical instruments for removal of lens materials and methods of use |
| AU2019333136B2 (en) | 2018-08-29 | 2022-11-17 | W. L. Gore & Associates, Inc. | Drug therapy delivery systems and methods |
| US20210322217A1 (en) * | 2018-08-29 | 2021-10-21 | W. L. Gore & Associates, Inc. | Ocular drainage system devices and methods |
| US12491112B2 (en) | 2018-08-31 | 2025-12-09 | New World Medical, Inc. | Ocular implants, ocular core assemblies and methods for making ocular implants |
| JP7504079B2 (ja) * | 2018-08-31 | 2024-06-21 | ニュー ワールド メディカル インコーポレイテッド | 眼用インプラント、インサータ・デバイス、及び眼用インプラントの挿入方法 |
| US11446156B2 (en) | 2018-10-25 | 2022-09-20 | Medos International Sarl | Expandable intervertebral implant, inserter instrument, and related methods |
| US11678983B2 (en) | 2018-12-12 | 2023-06-20 | W. L. Gore & Associates, Inc. | Implantable component with socket |
| WO2020150663A1 (en) | 2019-01-18 | 2020-07-23 | Shifamed Holdings, Llc | Adjustable flow glaucoma shunts and methods for making and using same |
| WO2020163850A1 (en) * | 2019-02-08 | 2020-08-13 | Mayo Foundation For Medical Education And Research | Implantation device |
| US12263123B2 (en) * | 2019-02-27 | 2025-04-01 | Innfocus, Inc. | Glaucoma device inserter |
| US11679028B2 (en) | 2019-03-06 | 2023-06-20 | Novartis Ag | Multi-dose ocular fluid delivery system |
| US12097145B2 (en) | 2019-03-06 | 2024-09-24 | Bausch + Lomb Ireland Limited | Vented multi-dose ocular fluid delivery system |
| US20220151827A1 (en) * | 2019-03-15 | 2022-05-19 | Minas Theodore Coroneo | Ophthalmic Compositions, and Ocular Uses Thereof, of Indigo Carmine |
| WO2020232015A1 (en) * | 2019-05-13 | 2020-11-19 | Verily Life Sciences Llc | Systems, devices and methods for optical interrogation of an implantable intraocular pressure sensor |
| CN119279913A (zh) | 2019-06-14 | 2025-01-10 | 安特雷克公司 | 支架 |
| US12551268B2 (en) | 2019-07-08 | 2026-02-17 | Shifamed Holdings, Llc | Minimally invasive bleb formation devices and methods for using such devices |
| WO2021007559A1 (en) | 2019-07-10 | 2021-01-14 | Anand Doraiswamy | Eye stents and delivery systems |
| US11504270B1 (en) | 2019-09-27 | 2022-11-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| JP7614193B2 (ja) | 2019-10-10 | 2025-01-15 | シファメド・ホールディングス・エルエルシー | 流量調整可能な緑内障用シャントならびに関連システム及び方法 |
| US12496218B1 (en) | 2019-11-12 | 2025-12-16 | Bausch + Lomb Ireland Limited | Fractionated topical ocular drug delivery methods and devices for use in the same |
| WO2021151007A1 (en) | 2020-01-23 | 2021-07-29 | Shifamed Holdings, Llc | Adjustable flow glaucoma shunts and associated systems and methods |
| WO2021163566A1 (en) | 2020-02-14 | 2021-08-19 | Shifamed Holdings, Llc | Shunting systems with rotation-based flow control assemblies, and associated systems and methods |
| EP4106695A4 (en) | 2020-02-18 | 2024-03-20 | Shifamed Holdings, LLC | ADJUSTABLE FLOW GLAUCOMA SHUNTS WITH NON-LINEAR FLOW CONTROL ELEMENTS AND ASSOCIATED SYSTEMS AND METHODS |
| US11426286B2 (en) | 2020-03-06 | 2022-08-30 | Eit Emerging Implant Technologies Gmbh | Expandable intervertebral implant |
| US11766355B2 (en) | 2020-03-19 | 2023-09-26 | Shifamed Holdings, Llc | Intraocular shunts with low-profile actuation elements and associated systems and methods |
| EP4135640B1 (en) | 2020-04-16 | 2025-12-24 | Shifamed Holdings, LLC | Adjustable glaucoma treatment devices and associated systems |
| CN115768384A (zh) | 2020-04-17 | 2023-03-07 | 科达隆治疗公司 | 流体动力致动的不含防腐剂分配系统 |
| US12290472B2 (en) | 2020-04-17 | 2025-05-06 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| US12090087B2 (en) | 2020-04-17 | 2024-09-17 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir |
| US11938057B2 (en) | 2020-04-17 | 2024-03-26 | Bausch + Lomb Ireland Limited | Hydrodynamically actuated preservative free dispensing system |
| CN115811995B (zh) | 2020-05-15 | 2023-11-03 | 视觉流公司 | 用于在哺乳动物眼睛的常规房水流出通路中植入的方法和设备 |
| CA3183402A1 (en) * | 2020-05-20 | 2021-11-25 | Iantrek, Inc. | System for shaping and implanting biologic intraocular stent for increased aqueous outflow and lowering of intraocular pressure |
| US12453656B2 (en) | 2020-05-20 | 2025-10-28 | Iantrek, Inc. | System for shaping and implanting biologic intraocular stent for increased aqueous outflow and lowering of intraocular pressure |
| JP2024503989A (ja) | 2021-01-11 | 2024-01-30 | アルコン インコーポレイティド | 粘弾性体送達のためのシステム及び方法 |
| US11865283B2 (en) | 2021-01-22 | 2024-01-09 | Shifamed Holdings, Llc | Adjustable shunting systems with plate assemblies, and associated systems and methods |
| US11850160B2 (en) | 2021-03-26 | 2023-12-26 | Medos International Sarl | Expandable lordotic intervertebral fusion cage |
| US11752009B2 (en) | 2021-04-06 | 2023-09-12 | Medos International Sarl | Expandable intervertebral fusion cage |
| EP4346720A4 (en) | 2021-05-28 | 2025-01-01 | Sight Sciences, Inc. | INTRAOCULAR DEVICES, SYSTEMS AND METHODS |
| EP4725463A3 (en) * | 2021-07-16 | 2026-04-22 | New World Medical, Inc. | Intraocular stent |
| US12527691B2 (en) | 2021-11-05 | 2026-01-20 | W. L. Gore & Associates, Inc. | Fluid drainage devices, systems, and methods |
| WO2023137375A1 (en) | 2022-01-12 | 2023-07-20 | Innovative Drive Corporation | Mechanical hole punch for the reduction of intraocular pressure and methods of use |
| US12090064B2 (en) | 2022-03-01 | 2024-09-17 | Medos International Sarl | Stabilization members for expandable intervertebral implants, and related systems and methods |
| WO2024112747A1 (en) | 2022-11-23 | 2024-05-30 | Iantrek, Inc. | Devices and systems for cutting, loading, and delivering biologic intraocular implants for increased aqueous outflow and lowering of intraocular pressure |
| US12544258B2 (en) | 2023-01-30 | 2026-02-10 | Jeffrey Whitsett | Aqueous micro shunt |
| US12245930B2 (en) | 2023-06-30 | 2025-03-11 | Alcon Inc. | System and methods for compensating for intraocular lens tilt |
| IL305586A (en) * | 2023-08-30 | 2025-03-01 | Mor Research Applic Ltd | Ophthalmic transfixing implant for use with intraocular lens, ophthalmic implantation tool for implanting same, and method for anchoring an intraocular lens in a human eye |
| US12440377B2 (en) | 2023-11-06 | 2025-10-14 | Aquea Health, Inc. | Eye stents and delivery systems and methods |
| US12569367B1 (en) | 2025-10-03 | 2026-03-10 | Michael Reynard | Systems and methods for endothelial regeneration of Schlemm's canal |
Family Cites Families (667)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US490152A (en) * | 1893-01-17 | Clutch for rock-drilling machines | ||
| US107398A (en) | 1870-09-13 | mooney | ||
| US2031754A (en) | 1932-11-04 | 1936-02-25 | Ernest J Sweetland | Extensible coupling |
| US2127903A (en) | 1936-05-05 | 1938-08-23 | Davis & Geck Inc | Tube for surgical purposes and method of preparing and using the same |
| US2269963A (en) | 1940-06-01 | 1942-01-13 | Wappler Frederick Charles | Implanting device |
| US3159161A (en) | 1962-11-14 | 1964-12-01 | Ness Richard Alton | Fistulizing canaliculus |
| US3416530A (en) | 1966-03-02 | 1968-12-17 | Richard A. Ness | Eyeball medication dispensing tablet |
| US3439675A (en) | 1966-06-14 | 1969-04-22 | Becton Dickinson Co | Deformable needle assembly |
| US3915172A (en) | 1970-05-27 | 1975-10-28 | Ceskoslovenska Akademie Ved | Capillary drain for glaucoma |
| US3717151A (en) | 1971-03-11 | 1973-02-20 | R Collett | Flesh penetrating apparatus |
| US3788327A (en) * | 1971-03-30 | 1974-01-29 | H Donowitz | Surgical implant device |
| SE353590B (https=) | 1971-10-01 | 1973-02-05 | J Kaller | |
| US3948871A (en) | 1972-04-21 | 1976-04-06 | George H. Butterfield And Son | Composition for hard type contact lens with wettable surface |
| US3863623A (en) | 1972-06-19 | 1975-02-04 | Medical College Of Georgia Fou | Method for microscintigraphic evaluation studies |
| US3948271A (en) | 1972-11-07 | 1976-04-06 | Taichiro Akiyama | Drain for the eardrum and apparatus for introducing the same |
| US3976077A (en) | 1975-02-03 | 1976-08-24 | Kerfoot Jr Franklin W | Eye surgery device |
| US4037604A (en) | 1976-01-05 | 1977-07-26 | Newkirk John B | Artifical biological drainage device |
| US4043346A (en) | 1976-03-10 | 1977-08-23 | Baylor College Of Medicine | Catheter |
| US4030480A (en) | 1976-05-13 | 1977-06-21 | Ernst Jochen Meyer | Ocular decompression process |
| US4168697A (en) | 1977-01-17 | 1979-09-25 | Cantekin Erdem I | Middle ear ventilating tube and method |
| US4113088A (en) | 1977-06-06 | 1978-09-12 | Binkhorst Richard D | Sterile package |
| US4175563A (en) | 1977-10-05 | 1979-11-27 | Arenberg Irving K | Biological drainage shunt |
| US4299227A (en) | 1979-10-19 | 1981-11-10 | Lincoff Harvey A | Ophthalmological appliance |
| US4402681A (en) | 1980-08-23 | 1983-09-06 | Haas Joseph S | Artificial implant valve for the regulation of intraocular pressure |
| US4366582A (en) | 1980-12-01 | 1983-01-04 | Faulkner Gerald D | Posterior chamber intraocular lens |
| NO147900C (no) * | 1981-03-12 | 1983-07-06 | Finn Skjaerpe | Mikrokirurgisk instrument. |
| US4457757A (en) | 1981-07-20 | 1984-07-03 | Molteno Anthony C B | Device for draining aqueous humour |
| US4428746A (en) * | 1981-07-29 | 1984-01-31 | Antonio Mendez | Glaucoma treatment device |
| US4449529A (en) | 1981-11-18 | 1984-05-22 | Becton Dickinson And Company | Automatic retractable lancet assembly |
| DE3206834A1 (de) | 1982-02-26 | 1983-09-15 | Walter Dr. 4000 Düsseldorf Messingschlager | Drainage-roehrchen zum einsetzen in einen operativ angelegten zugang zu einer koerperhoehlung |
| US4554918A (en) | 1982-07-28 | 1985-11-26 | White Thomas C | Ocular pressure relief device |
| JPS5985153A (ja) * | 1982-11-08 | 1984-05-17 | Hitachi Ltd | 冗長化制御装置 |
| US4521210A (en) * | 1982-12-27 | 1985-06-04 | Wong Vernon G | Eye implant for relieving glaucoma, and device and method for use therewith |
| FR2553658A1 (fr) | 1983-10-19 | 1985-04-26 | Neidich Warren | Valve-implant pour soigner le glaucome |
| US4560383A (en) | 1983-10-27 | 1985-12-24 | Leiske Larry G | Anterior chamber intraocular lens |
| US4578058A (en) | 1984-04-02 | 1986-03-25 | Grandon Stanley C | Intraocular catheter apparatus and method of use |
| US4787885A (en) | 1984-04-06 | 1988-11-29 | Binder Perry S | Hydrogel seton |
| US4634418A (en) * | 1984-04-06 | 1987-01-06 | Binder Perry S | Hydrogel seton |
| DE3447642C1 (de) | 1984-12-28 | 1986-09-18 | Bernhard M. Dr. 5600 Wuppertal Cramer | Lenkbarer Fuehrungsdraht fuer Katheter |
| US4604087A (en) | 1985-02-26 | 1986-08-05 | Joseph Neil H | Aqueous humor drainage device |
| US4642090A (en) | 1985-03-04 | 1987-02-10 | Utrata Peter J | Disposable combination scalpel blade and incision irrigator for ophthalmological use |
| US4820626A (en) * | 1985-06-06 | 1989-04-11 | Thomas Jefferson University | Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself |
| US4632842A (en) | 1985-06-20 | 1986-12-30 | Atrium Medical Corporation | Glow discharge process for producing implantable devices |
| US4718907A (en) * | 1985-06-20 | 1988-01-12 | Atrium Medical Corporation | Vascular prosthesis having fluorinated coating with varying F/C ratio |
| US4883864A (en) | 1985-09-06 | 1989-11-28 | Minnesota Mining And Manufacturing Company | Modified collagen compound and method of preparation |
| US4733665C2 (en) * | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
| US4692142A (en) | 1986-02-24 | 1987-09-08 | Dignam Bernard J | Sutureless infusion cannula for ophthalmic surgery |
| NZ215409A (en) * | 1986-03-07 | 1989-02-24 | Anthony Christopher Be Molteno | Implant for drainage of aqueous humour in glaucoma |
| CH670760A5 (https=) * | 1986-06-02 | 1989-07-14 | Sulzer Ag | |
| US4722724A (en) * | 1986-06-23 | 1988-02-02 | Stanley Schocket | Anterior chamber tube shunt to an encircling band, and related surgical procedure |
| US4826478A (en) | 1986-06-23 | 1989-05-02 | Stanley Schocket | Anterior chamber tube shunt to an encircling band, and related surgical procedure |
| US4867173A (en) | 1986-06-30 | 1989-09-19 | Meadox Surgimed A/S | Steerable guidewire |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US4782819A (en) | 1987-02-25 | 1988-11-08 | Adair Edwin Lloyd | Optical catheter |
| US4846793A (en) * | 1987-03-18 | 1989-07-11 | Endocon, Inc. | Injector for implanting multiple pellet medicaments |
| DE3715699A1 (de) | 1987-05-12 | 1988-12-01 | Foerster Ernst | Katheter und endoskop zur transpapillaeren darstellung der gallenblase |
| US4846172A (en) | 1987-05-26 | 1989-07-11 | Berlin Michael S | Laser-delivery eye-treatment method |
| US4900300A (en) * | 1987-07-06 | 1990-02-13 | Lee David A | Surgical instrument |
| CA1295907C (en) | 1987-08-06 | 1992-02-18 | Thomas C. White | Glaucoma drainage in the lacrimal system |
| US4886488A (en) | 1987-08-06 | 1989-12-12 | White Thomas C | Glaucoma drainage the lacrimal system and method |
| EP0375676A1 (en) | 1987-08-19 | 1990-07-04 | BERG, Olle | A drainage tube for sinus maxillaris, a means for its insertion and a means for making a hole for its positioning |
| US4870953A (en) | 1987-11-13 | 1989-10-03 | Donmicheal T Anthony | Intravascular ultrasonic catheter/probe and method for treating intravascular blockage |
| US4997652A (en) * | 1987-12-22 | 1991-03-05 | Visionex | Biodegradable ocular implants |
| US4853224A (en) | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
| US5053044A (en) | 1988-01-11 | 1991-10-01 | Devices For Vascular Intervention, Inc. | Catheter and method for making intravascular incisions |
| US4800870A (en) | 1988-03-11 | 1989-01-31 | Reid Jr Ben A | Method and apparatus for bile duct exploration |
| US4936825A (en) | 1988-04-11 | 1990-06-26 | Ungerleider Bruce A | Method for reducing intraocular pressure caused by glaucoma |
| CA1334168C (en) | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
| US5327577A (en) * | 1988-06-14 | 1994-07-05 | Telefonaktiebolaget L M Ericsson | Handover method for mobile radio system |
| US5005577A (en) | 1988-08-23 | 1991-04-09 | Frenkel Ronald E P | Intraocular lens pressure monitoring device |
| WO1990001969A1 (en) * | 1988-08-24 | 1990-03-08 | Slepian Marvin J | Biodegradable polymeric endoluminal sealing |
| US5681275A (en) | 1988-10-07 | 1997-10-28 | Ahmed; Abdul Mateen | Ophthalmological device with adaptable multiple distribution plates |
| US5785674A (en) | 1988-10-07 | 1998-07-28 | Mateen; Ahmed Abdul | Device and method for treating glaucoma |
| US5116327A (en) | 1989-06-05 | 1992-05-26 | Helix Medical, Inc. | Hysterectomy drain appliance |
| US4991602A (en) | 1989-06-27 | 1991-02-12 | Flexmedics Corporation | Flexible guide wire with safety tip |
| US5817075A (en) | 1989-08-14 | 1998-10-06 | Photogenesis, Inc. | Method for preparation and transplantation of planar implants and surgical instrument therefor |
| US4986810A (en) | 1989-09-01 | 1991-01-22 | Neal Semrad | Toggle catheter |
| US5169386A (en) | 1989-09-11 | 1992-12-08 | Bruce B. Becker | Method and catheter for dilatation of the lacrimal system |
| FR2651668B1 (fr) * | 1989-09-12 | 1991-12-27 | Leon Claude | Ensemble microscope-endoscope utile notamment en chirurgie. |
| US5053040A (en) | 1989-11-09 | 1991-10-01 | Goldsmith Iii Manning M | Method of performing a myringotomy |
| USRE35390E (en) | 1989-11-17 | 1996-12-03 | Smith; Stewart G. | Pressure relieving device and process for implanting |
| US4946436A (en) | 1989-11-17 | 1990-08-07 | Smith Stewart G | Pressure-relieving device and process for implanting |
| US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
| US4968296A (en) | 1989-12-20 | 1990-11-06 | Robert Ritch | Transscleral drainage implant device for the treatment of glaucoma |
| US5092837A (en) * | 1989-12-20 | 1992-03-03 | Robert Ritch | Method for the treatment of glaucoma |
| DE4030004A1 (de) | 1990-01-05 | 1992-03-26 | Heino Dr Hermeking | Instrument mit hakenplatte zum implantieren einer kuenstlichen linse |
| US5221255A (en) | 1990-01-10 | 1993-06-22 | Mahurkar Sakharam D | Reinforced multiple lumen catheter |
| US5073163A (en) | 1990-01-29 | 1991-12-17 | Lippman Myron E | Apparatus for treating glaucoma |
| RU2022539C1 (ru) | 1990-01-29 | 1994-11-15 | Мир Сергеевич Ремизов | Способ лечения глаукомы |
| US5180362A (en) * | 1990-04-03 | 1993-01-19 | Worst J G F | Gonio seton |
| US5129895A (en) | 1990-05-16 | 1992-07-14 | Sunrise Technologies, Inc. | Laser sclerostomy procedure |
| US5127901A (en) | 1990-05-18 | 1992-07-07 | Odrich Ronald B | Implant with subconjunctival arch |
| US5041081A (en) | 1990-05-18 | 1991-08-20 | Odrich Ronald B | Ocular implant for controlling glaucoma |
| US5178604A (en) * | 1990-05-31 | 1993-01-12 | Iovision, Inc. | Glaucoma implant |
| US5397300A (en) * | 1990-05-31 | 1995-03-14 | Iovision, Inc. | Glaucoma implant |
| US5476445A (en) | 1990-05-31 | 1995-12-19 | Iovision, Inc. | Glaucoma implant with a temporary flow restricting seal |
| WO1992000112A1 (en) | 1990-06-25 | 1992-01-09 | Ungerleider Bruce A | Apparatus for reducing intraocular pressure |
| US5725529A (en) | 1990-09-25 | 1998-03-10 | Innovasive Devices, Inc. | Bone fastener |
| US5688261A (en) | 1990-11-07 | 1997-11-18 | Premier Laser Systems, Inc. | Transparent laser surgical probe |
| US5273530A (en) | 1990-11-14 | 1993-12-28 | The University Of Rochester | Intraretinal delivery and withdrawal instruments |
| DE4104702C2 (de) * | 1991-02-15 | 1996-01-18 | Malte Neuss | Implantate für Organwege in Wendelform |
| US5454796A (en) | 1991-04-09 | 1995-10-03 | Hood Laboratories | Device and method for controlling intraocular fluid pressure |
| US5312394A (en) | 1991-04-29 | 1994-05-17 | Hugh Beckman | Apparatus and method for surgically performing a filtering operation on an eye for glaucoma |
| US5246451A (en) | 1991-04-30 | 1993-09-21 | Medtronic, Inc. | Vascular prosthesis and method |
| US5358492A (en) | 1991-05-02 | 1994-10-25 | Feibus Miriam H | Woven surgical drain and method of making |
| US6007511A (en) | 1991-05-08 | 1999-12-28 | Prywes; Arnold S. | Shunt valve and therapeutic delivery system for treatment of glaucoma and methods and apparatus for its installation |
| US5300020A (en) * | 1991-05-31 | 1994-04-05 | Medflex Corporation | Surgically implantable device for glaucoma relief |
| US5326345A (en) | 1991-08-14 | 1994-07-05 | Price Jr Francis W | Eye filtration prostheses |
| US5171213A (en) | 1991-08-14 | 1992-12-15 | Price Jr Francis W | Technique for fistulization of the eye and an eye filtration prosthesis useful therefor |
| US5500013A (en) | 1991-10-04 | 1996-03-19 | Scimed Life Systems, Inc. | Biodegradable drug delivery vascular stent |
| US5464450A (en) * | 1991-10-04 | 1995-11-07 | Scimed Lifesystems Inc. | Biodegradable drug delivery vascular stent |
| GB2260585A (en) | 1991-10-09 | 1993-04-21 | Avdel Systems Ltd | Self-plugging blind rivet |
| US5290310A (en) | 1991-10-30 | 1994-03-01 | Howmedica, Inc. | Hemostatic implant introducer |
| US5360399A (en) * | 1992-01-10 | 1994-11-01 | Robert Stegmann | Method and apparatus for maintaining the normal intraocular pressure |
| US5207685A (en) * | 1992-02-11 | 1993-05-04 | Cinberg James Z | Tympanic ventilation tube and related technique |
| US5334137A (en) | 1992-02-21 | 1994-08-02 | Eagle Vision, Inc. | Lacrimal fluid control device |
| US5346464A (en) | 1992-03-10 | 1994-09-13 | Camras Carl B | Method and apparatus for reducing intraocular pressure |
| US5284476A (en) | 1992-03-20 | 1994-02-08 | Koch Paul S | Nuclear hydrolysis cannula |
| US5415666A (en) | 1992-03-23 | 1995-05-16 | Advanced Surgical, Inc. | Tethered clamp retractor |
| US5368601A (en) | 1992-04-30 | 1994-11-29 | Lasersurge, Inc. | Trocar wound closure device |
| KR100253515B1 (ko) | 1992-05-22 | 2000-05-01 | 요시다 쇼지 | 녹내장 치료용 의약 조성물 |
| US5370641A (en) | 1992-05-22 | 1994-12-06 | O'donnell, Jr.; Francis E. | Laser trabeculodissection |
| DE4219299C2 (de) | 1992-06-12 | 1994-03-24 | Leica Mikroskopie & Syst | Mikroskop |
| US5767079A (en) | 1992-07-08 | 1998-06-16 | Celtrix Pharmaceuticals, Inc. | Method of treating ophthalmic disorders using TGF -β |
| US5290295A (en) * | 1992-07-15 | 1994-03-01 | Querals & Fine, Inc. | Insertion tool for an intraluminal graft procedure |
| US6197056B1 (en) * | 1992-07-15 | 2001-03-06 | Ras Holding Corp. | Segmented scleral band for treatment of presbyopia and other eye disorders |
| JP3739411B2 (ja) * | 1992-09-08 | 2006-01-25 | 敬二 伊垣 | 脈管ステント及びその製造方法並びに脈管ステント装置 |
| US5318513A (en) * | 1992-09-24 | 1994-06-07 | Leib Martin L | Canalicular balloon fixation stent |
| US5370607A (en) | 1992-10-28 | 1994-12-06 | Annuit Coeptis, Inc. | Glaucoma implant device and method for implanting same |
| WO1994013234A1 (en) | 1992-12-17 | 1994-06-23 | Michael Andrew Coote | Implant device and method for treatment of glaucoma |
| US5338291A (en) | 1993-02-03 | 1994-08-16 | Pudenz-Schulte Medical Research Corporation | Glaucoma shunt and method for draining aqueous humor |
| CA2158443C (en) | 1993-03-16 | 2003-11-25 | Stephen E. Hughes | Method for preparation and transplantation of volute grafts and surgical instrument therefor |
| US5342370A (en) | 1993-03-19 | 1994-08-30 | University Of Miami | Method and apparatus for implanting an artifical meshwork in glaucoma surgery |
| IL105828A (en) | 1993-05-28 | 1999-06-20 | Medinol Ltd | Medical stent |
| US5731294A (en) | 1993-07-27 | 1998-03-24 | Hybridon, Inc. | Inhibition of neovasularization using VEGF-specific oligonucleotides |
| US6184250B1 (en) | 1993-08-03 | 2001-02-06 | Alcon Laboratories, Inc. | Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension |
| US5735892A (en) | 1993-08-18 | 1998-04-07 | W. L. Gore & Associates, Inc. | Intraluminal stent graft |
| US5653724A (en) | 1993-08-18 | 1997-08-05 | Imonti; Maurice M. | Angled phacoemulsifier tip |
| FR2710269A1 (fr) | 1993-09-22 | 1995-03-31 | Voir Vivre | Dispositif implantable pour le traitement des Óoedèmes . |
| FI934513A7 (fi) * | 1993-10-13 | 1995-04-14 | Leiras Oy | Implantaattien injektointiin tarkoitettu laite |
| US5639278A (en) * | 1993-10-21 | 1997-06-17 | Corvita Corporation | Expandable supportive bifurcated endoluminal grafts |
| US5695479A (en) | 1993-11-01 | 1997-12-09 | Jagpal; Ravindar | Instrument, system, kit and method for catheterization procedures |
| US5443505A (en) | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
| US5445637A (en) | 1993-12-06 | 1995-08-29 | American Cyanamid Company | Method and apparatus for preventing posterior capsular opacification |
| US6049772A (en) * | 1994-01-21 | 2000-04-11 | Fdi/Genesis | System for managing hedged investments for life insurance companies |
| KR100342025B1 (ko) * | 1994-02-07 | 2003-03-15 | 가부시키가이샤 이가키 이료 세케이 | 스텐트장치및스텐트공급시스템 |
| US5743868A (en) * | 1994-02-14 | 1998-04-28 | Brown; Reay H. | Corneal pressure-regulating implant device |
| US6135977A (en) | 1994-02-16 | 2000-10-24 | Possis Medical, Inc. | Rheolytic catheter |
| US5516522A (en) * | 1994-03-14 | 1996-05-14 | Board Of Supervisors Of Louisiana State University | Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same |
| US6165210A (en) | 1994-04-01 | 2000-12-26 | Gore Enterprise Holdings, Inc. | Self-expandable helical intravascular stent and stent-graft |
| WO1995026734A1 (en) | 1994-04-04 | 1995-10-12 | Freeman William R | Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure |
| US5716394A (en) * | 1994-04-29 | 1998-02-10 | W. L. Gore & Associates, Inc. | Blood contact surfaces using extracellular matrix synthesized in vitro |
| IL109499A (en) * | 1994-05-02 | 1998-01-04 | Univ Ramot | Implant device for draining excess intraocular fluid |
| FR2721499B1 (fr) | 1994-06-22 | 1997-01-03 | Opsia | Implant de trabéculectomie. |
| US6405732B1 (en) | 1994-06-24 | 2002-06-18 | Curon Medical, Inc. | Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors |
| US5725546A (en) | 1994-06-24 | 1998-03-10 | Target Therapeutics, Inc. | Detachable microcoil delivery catheter |
| US6177427B1 (en) | 1994-06-28 | 2001-01-23 | Alcon Laboratories, Inc. | Treatment of glaucoma and ocular hypertension |
| US5520631A (en) * | 1994-07-22 | 1996-05-28 | Wound Healing Of Oklahoma | Method and apparatus for lowering the intraocular pressure of an eye |
| US6102045A (en) | 1994-07-22 | 2000-08-15 | Premier Laser Systems, Inc. | Method and apparatus for lowering the intraocular pressure of an eye |
| US5704907A (en) * | 1994-07-22 | 1998-01-06 | Wound Healing Of Oklahoma | Method and apparatus for lowering the intraocular pressure of an eye |
| US5665114A (en) | 1994-08-12 | 1997-09-09 | Meadox Medicals, Inc. | Tubular expanded polytetrafluoroethylene implantable prostheses |
| SE9402816D0 (sv) | 1994-08-24 | 1994-08-24 | Pharmacia Ab | Method and meams for drug administration |
| US5462558A (en) | 1994-08-29 | 1995-10-31 | United States Surgical Corporation | Suture clip applier |
| DE4433104C1 (de) | 1994-09-16 | 1996-05-02 | Fraunhofer Ges Forschung | Einrichtung zur Messung mechanischer Eigenschaften von biologischem Gewebe |
| US5702419A (en) | 1994-09-21 | 1997-12-30 | Wake Forest University | Expandable, intraluminal stents |
| ES2235174T3 (es) * | 1994-10-17 | 2005-07-01 | Kabushikikaisha Igaki Iryo Sekkei | Stent liberador de medicamento. |
| US6063396A (en) * | 1994-10-26 | 2000-05-16 | Houston Biotechnology Incorporated | Methods and compositions for the modulation of cell proliferation and wound healing |
| US6063116A (en) * | 1994-10-26 | 2000-05-16 | Medarex, Inc. | Modulation of cell proliferation and wound healing |
| US5643321A (en) | 1994-11-10 | 1997-07-01 | Innovasive Devices | Suture anchor assembly and methods |
| JP3642812B2 (ja) * | 1994-11-17 | 2005-04-27 | 株式会社町田製作所 | 医療用観察装置 |
| US5601094A (en) * | 1994-11-22 | 1997-02-11 | Reiss; George R. | Ophthalmic shunt |
| US5602143A (en) | 1994-12-08 | 1997-02-11 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of guanylate cyclase inhibitors |
| US6228873B1 (en) * | 1994-12-09 | 2001-05-08 | The Regents Of The University Of California | Method for enhancing outflow of aqueous humor in treatment of glaucoma |
| US5725493A (en) * | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
| US5433701A (en) | 1994-12-21 | 1995-07-18 | Rubinstein; Mark H. | Apparatus for reducing ocular pressure |
| US5556400A (en) | 1994-12-27 | 1996-09-17 | Tunis; Scott W. | Methods of preparing and inserting flexible intraocular lenses and a configuration for flexible intraocular lenses |
| US5891084A (en) | 1994-12-27 | 1999-04-06 | Lee; Vincent W. | Multiple chamber catheter delivery system |
| US5558630A (en) | 1994-12-30 | 1996-09-24 | Fisher; Bret L. | Intrascleral implant and method for the regulation of intraocular pressure |
| GB2296663A (en) | 1995-01-03 | 1996-07-10 | Ahmed Salih Mahmud | Drainage device for alleviating excess ophthalmic fluid pressure |
| US5522797A (en) * | 1995-01-03 | 1996-06-04 | Ivy Laboratories, Inc. | Slide action veterinary implanter |
| CA2212412A1 (en) | 1995-02-10 | 1996-08-15 | The University Of Toronto Innovations Foundation | Deprenyl compounds for treatment of glaucoma |
| US5792099A (en) | 1995-02-14 | 1998-08-11 | Decamp; Dennis | Syringe and cannula for insertion of viscoelastic material into an eye and method of using same |
| US6059772A (en) | 1995-03-10 | 2000-05-09 | Candela Corporation | Apparatus and method for treating glaucoma using a gonioscopic laser trabecular ablation procedure |
| BE1009278A3 (fr) * | 1995-04-12 | 1997-01-07 | Corvita Europ | Tuteur auto-expansible pour dispositif medical a introduire dans une cavite d'un corps, et dispositif medical muni d'un tel tuteur. |
| US5626558A (en) | 1995-05-05 | 1997-05-06 | Suson; John | Adjustable flow rate glaucoma shunt and method of using same |
| DE69633074T2 (de) | 1995-05-14 | 2004-12-30 | Optonol Ltd. | Intraokulares implantat, einführgerät sowie implantierungsverfahren |
| IL113723A (en) * | 1995-05-14 | 2002-11-10 | Optonol Ltd | Intraocular implant |
| US5968058A (en) | 1996-03-27 | 1999-10-19 | Optonol Ltd. | Device for and method of implanting an intraocular implant |
| WO1996037167A1 (en) * | 1995-05-25 | 1996-11-28 | Raychem Corporation | Stent assembly |
| US5723005A (en) * | 1995-06-07 | 1998-03-03 | Herrick Family Limited Partnership | Punctum plug having a collapsible flared section and method |
| DE69630030T2 (de) * | 1995-06-08 | 2004-06-09 | Ave Galway Ltd. | Endovaskularer stent |
| US6194415B1 (en) | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
| US5913852A (en) | 1995-07-21 | 1999-06-22 | Nemours Foundation | Drain cannula |
| US5934285A (en) | 1995-07-27 | 1999-08-10 | Michiel S. Kritzinger | Method for reducing irregular astigmatism and debris/epithelium in the interface during lamellar corneal flap/cap surgery |
| US5766243A (en) * | 1995-08-21 | 1998-06-16 | Oasis Medical, Inc. | Abrasive polished canalicular implant |
| US5662600A (en) | 1995-09-29 | 1997-09-02 | Pudenz-Schulte Medical Research Corporation | Burr-hole flow control device |
| US5547993A (en) | 1995-10-24 | 1996-08-20 | Mitsubishi Chemical Corporation | Therapeutic agent for glaucoma |
| US5836939A (en) | 1995-10-25 | 1998-11-17 | Plc Medical Systems, Inc. | Surgical laser handpiece |
| US5742440A (en) * | 1995-10-25 | 1998-04-21 | Eastman Kodak Company | Actuator with reduced lens tilt error |
| US5741292A (en) | 1995-10-26 | 1998-04-21 | Eagle Vision | Punctum dilating and plug inserting instrument with push-button plug release |
| US6045557A (en) * | 1995-11-10 | 2000-04-04 | Baxter International Inc. | Delivery catheter and method for positioning an intraluminal graft |
| US5651783A (en) | 1995-12-20 | 1997-07-29 | Reynard; Michael | Fiber optic sleeve for surgical instruments |
| US5722948A (en) | 1996-02-14 | 1998-03-03 | Gross; Fredric J. | Covering for an ocular device |
| US5798380A (en) | 1996-02-21 | 1998-08-25 | Wisconsin Alumni Research Foundation | Cytoskeletal active agents for glaucoma therapy |
| US6299895B1 (en) | 1997-03-24 | 2001-10-09 | Neurotech S.A. | Device and method for treating ophthalmic diseases |
| US5807302A (en) * | 1996-04-01 | 1998-09-15 | Wandel; Thaddeus | Treatment of glaucoma |
| US6629981B2 (en) | 2000-07-06 | 2003-10-07 | Endocare, Inc. | Stent delivery system |
| US5830179A (en) * | 1996-04-09 | 1998-11-03 | Endocare, Inc. | Urological stent therapy system and method |
| US5865831A (en) * | 1996-04-17 | 1999-02-02 | Premier Laser Systems, Inc. | Laser surgical procedures for treatment of glaucoma |
| NL1002898C2 (nl) | 1996-04-18 | 1997-10-21 | Cordis Europ | Katheter met markeerhuls. |
| US5932299A (en) | 1996-04-23 | 1999-08-03 | Katoot; Mohammad W. | Method for modifying the surface of an object |
| US6530896B1 (en) * | 1996-05-13 | 2003-03-11 | James B. Elliott | Apparatus and method for introducing an implant |
| US6074872A (en) * | 1996-05-15 | 2000-06-13 | The Scripps Research Institute | Cortistatin: nucleic acids that encode these neuropeptides |
| US5670161A (en) | 1996-05-28 | 1997-09-23 | Healy; Kevin E. | Biodegradable stent |
| US5669501A (en) | 1996-06-05 | 1997-09-23 | Xomed Surgical Products, Inc. | Package and method for delivering a medical implant |
| US5681323A (en) * | 1996-07-15 | 1997-10-28 | Arick; Daniel S. | Emergency cricothyrotomy tube insertion |
| US5755682A (en) | 1996-08-13 | 1998-05-26 | Heartstent Corporation | Method and apparatus for performing coronary artery bypass surgery |
| US5830139A (en) | 1996-09-04 | 1998-11-03 | Abreu; Marcio M. | Tonometer system for measuring intraocular pressure by applanation and/or indentation |
| US6120460A (en) | 1996-09-04 | 2000-09-19 | Abreu; Marcio Marc | Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions |
| US5655548A (en) | 1996-09-16 | 1997-08-12 | Circulation, Inc. | Method for treatment of ischemic heart disease by providing transvenous myocardial perfusion |
| RU2143250C1 (ru) | 1996-09-25 | 1999-12-27 | Астахов Сергей Юрьевич | Способ лечения больных с сочетанием катаракты и глаукомы |
| US5733256A (en) | 1996-09-26 | 1998-03-31 | Micro Medical Devices | Integrated phacoemulsification system |
| US5886822A (en) * | 1996-10-08 | 1999-03-23 | The Microoptical Corporation | Image combining system for eyeglasses and face masks |
| US6007510A (en) | 1996-10-25 | 1999-12-28 | Anamed, Inc. | Implantable devices and methods for controlling the flow of fluids within the body |
| US6881197B1 (en) | 1996-10-25 | 2005-04-19 | Anamed, Inc. | Sutureless implantable device and method for treatment of glaucoma |
| US5925342A (en) | 1996-11-13 | 1999-07-20 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers |
| US5807244A (en) | 1996-11-15 | 1998-09-15 | Barot; Jagdish Shantilal | Single use disposable iris retractor |
| US5941250A (en) | 1996-11-21 | 1999-08-24 | University Of Louisville Research Foundation Inc. | Retinal tissue implantation method |
| AUPO394496A0 (en) | 1996-11-29 | 1997-01-02 | Lions Eye Institute | Biological microfistula tube and implantation method and apparatus |
| FR2757068B1 (fr) | 1996-12-13 | 1999-04-23 | Jussmann Alberto | Drain auto-fixant |
| DE19651951C2 (de) | 1996-12-16 | 2002-06-27 | Adeva Medical Ges Fuer Entwick | Shunt-Ventil |
| US6261256B1 (en) | 1996-12-20 | 2001-07-17 | Abdul Mateen Ahmed | Pocket medical valve & method |
| US5713844A (en) * | 1997-01-10 | 1998-02-03 | Peyman; Gholam A. | Device and method for regulating intraocular pressure |
| GB9700390D0 (en) | 1997-01-10 | 1997-02-26 | Biocompatibles Ltd | Device for use in the eye |
| US6780165B2 (en) | 1997-01-22 | 2004-08-24 | Advanced Medical Optics | Micro-burst ultrasonic power delivery |
| DE19705815C2 (de) | 1997-02-15 | 1999-02-11 | Heidelberg Engineering Optisch | Medizinisches Gerät zur Mikrochirurgie am Auge |
| FR2759577B1 (fr) | 1997-02-17 | 1999-08-06 | Corneal Ind | Implant de sclerectomie profonde |
| US6071286A (en) * | 1997-02-19 | 2000-06-06 | Mawad; Michel E. | Combination angioplasty balloon/stent deployment device |
| US5893837A (en) | 1997-02-28 | 1999-04-13 | Staar Surgical Company, Inc. | Glaucoma drain implanting device and method |
| US6059812A (en) * | 1997-03-21 | 2000-05-09 | Schneider (Usa) Inc. | Self-expanding medical device for centering radioactive treatment sources in body vessels |
| JP3827429B2 (ja) | 1997-04-03 | 2006-09-27 | オリンパス株式会社 | 手術用顕微鏡 |
| US5882327A (en) * | 1997-04-17 | 1999-03-16 | Jacob; Jean T. | Long-term glaucoma drainage implant |
| US6050970A (en) * | 1997-05-08 | 2000-04-18 | Pharmacia & Upjohn Company | Method and apparatus for inserting a glaucoma implant in an anterior and posterior segment of the eye |
| US5752928A (en) * | 1997-07-14 | 1998-05-19 | Rdo Medical, Inc. | Glaucoma pressure regulator |
| US5980928A (en) * | 1997-07-29 | 1999-11-09 | Terry; Paul B. | Implant for preventing conjunctivitis in cattle |
| US5830171A (en) | 1997-08-12 | 1998-11-03 | Odyssey Medical, Inc. | Punctal occluder |
| EP0898947A3 (de) | 1997-08-15 | 1999-09-08 | GRIESHABER & CO. AG SCHAFFHAUSEN | Verfahren und Vorrichtung zum Verbessern des Kammerwasserabflusses in einem Auge |
| US6004302A (en) | 1997-08-28 | 1999-12-21 | Brierley; Lawrence A. | Cannula |
| US6274138B1 (en) | 1997-09-03 | 2001-08-14 | Incyte Genomics, Inc. | Human mitochondrial malate dehydrogenase |
| US5980548A (en) * | 1997-10-29 | 1999-11-09 | Kensey Nash Corporation | Transmyocardial revascularization system |
| US6159458A (en) | 1997-11-04 | 2000-12-12 | Insite Vision | Sustained release ophthalmic compositions containing water soluble medicaments |
| US8313454B2 (en) | 1997-11-20 | 2012-11-20 | Optonol Ltd. | Fluid drainage device, delivery device, and associated methods of use and manufacture |
| US6203513B1 (en) | 1997-11-20 | 2001-03-20 | Optonol Ltd. | Flow regulating implant, method of manufacture, and delivery device |
| US6036682A (en) | 1997-12-02 | 2000-03-14 | Scimed Life Systems, Inc. | Catheter having a plurality of integral radiopaque bands |
| EP1039847A1 (en) | 1997-12-15 | 2000-10-04 | Prolifix Medical, Inc. | Vascular stent for reduction of restenosis |
| US5927585A (en) | 1997-12-17 | 1999-07-27 | Senco Products, Inc. | Electric multiple impact fastener driving tool |
| US6050999A (en) * | 1997-12-18 | 2000-04-18 | Keravision, Inc. | Corneal implant introducer and method of use |
| US7780623B2 (en) | 1998-01-29 | 2010-08-24 | Soltanpour David P | Implantable pump apparatuses |
| US6682500B2 (en) | 1998-01-29 | 2004-01-27 | David Soltanpour | Synthetic muscle based diaphragm pump apparatuses |
| US6589198B1 (en) | 1998-01-29 | 2003-07-08 | David Soltanpour | Implantable micro-pump assembly |
| US6168575B1 (en) * | 1998-01-29 | 2001-01-02 | David Pyam Soltanpour | Method and apparatus for controlling intraocular pressure |
| US6224570B1 (en) | 1998-02-06 | 2001-05-01 | Possis Medical, Inc. | Rheolytic thrombectomy catheter and method of using same |
| US6030416A (en) | 1998-02-13 | 2000-02-29 | Pharmacia & Upjohn Ab | Medical implants of stretch-crystallizable elastomers and methods of implantation |
| JP3732404B2 (ja) * | 1998-02-23 | 2006-01-05 | ニーモサイエンス ゲーエムベーハー | 形状記憶ポリマー組成物、形状記憶製品を形成する方法、および形状を記憶する組成物を形成する方法 |
| US6160084A (en) * | 1998-02-23 | 2000-12-12 | Massachusetts Institute Of Technology | Biodegradable shape memory polymers |
| JP2002512954A (ja) | 1998-04-24 | 2002-05-08 | マイトコー | ミトコンドリア関連疾患を処置するための化合物および方法 |
| US6371960B2 (en) | 1998-05-19 | 2002-04-16 | Bausch & Lomb Surgical, Inc. | Device for inserting a flexible intraocular lens |
| US6231853B1 (en) | 1998-06-01 | 2001-05-15 | Incyte Pharmaceuticals, Inc. | Human glutathione peroxidase-6 |
| US6306114B1 (en) | 1998-06-16 | 2001-10-23 | Eagle Vision, Inc. | Valved canalicular plug for lacrimal duct occlusion |
| US6077299A (en) * | 1998-06-22 | 2000-06-20 | Eyetronic, Llc | Non-invasively adjustable valve implant for the drainage of aqueous humor in glaucoma |
| US6319274B1 (en) | 1998-06-22 | 2001-11-20 | John H. Shadduck | Devices and techniques for light-mediated stimulation of trabecular meshwork in glaucoma therapy |
| US6402734B1 (en) | 1998-07-02 | 2002-06-11 | Jeffrey N. Weiss | Apparatus and method for cannulating retinal blood vessels |
| US6591838B2 (en) | 1998-07-06 | 2003-07-15 | Scimed Life Systems, Inc. | Implant system and method for bulking tissue |
| US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
| US6309374B1 (en) | 1998-08-03 | 2001-10-30 | Insite Vision Incorporated | Injection apparatus and method of using same |
| US6146387A (en) | 1998-08-26 | 2000-11-14 | Linvatec Corporation | Cannulated tissue anchor system |
| DE19840047B4 (de) | 1998-09-02 | 2004-07-08 | Neuhann, Thomas, Prof.Dr.med. | Vorrichtung zur gezielten Verbesserung und/oder dauerhaften Gewährleistung des Durchlässigkeitsvermögens für Augenkammerwasser durch das Trabekelwerk in den Schlemmschen Kanal |
| KR100300527B1 (ko) | 1998-09-03 | 2001-10-27 | 윤덕용 | 밀봉형무선압력측정소자및그제조방법 |
| US6290728B1 (en) | 1998-09-10 | 2001-09-18 | Percardia, Inc. | Designs for left ventricular conduit |
| ATE322230T1 (de) | 1998-09-10 | 2006-04-15 | Percardia Inc | Tmr vorrichtung |
| US6264668B1 (en) | 1998-09-16 | 2001-07-24 | Arnold S. Prywes | Ophthalmologic instrument for producing a fistula in the sclera |
| ES2237168T3 (es) | 1998-09-30 | 2005-07-16 | Bard Peripheral Vascular, Inc. | Mecanismo de suministro para stent implantable. |
| US6241721B1 (en) * | 1998-10-09 | 2001-06-05 | Colette Cozean | Laser surgical procedures for treatment of glaucoma |
| US6254612B1 (en) | 1998-10-22 | 2001-07-03 | Cordis Neurovascular, Inc. | Hydraulic stent deployment system |
| US6454787B1 (en) | 1998-12-11 | 2002-09-24 | C. R. Bard, Inc. | Collagen hemostatic foam |
| GB9827415D0 (en) * | 1998-12-11 | 1999-02-03 | Wild Andrew M | Surgical apparatus and method for occluding a body passageway |
| US6363938B2 (en) * | 1998-12-22 | 2002-04-02 | Angiotrax, Inc. | Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth |
| US6348042B1 (en) * | 1999-02-02 | 2002-02-19 | W. Lee Warren, Jr. | Bioactive shunt |
| US6074395A (en) | 1999-02-02 | 2000-06-13 | Linvatec Corporation | Cannulated tissue anchor insertion system |
| US6193656B1 (en) * | 1999-02-08 | 2001-02-27 | Robert E. Jeffries | Intraocular pressure monitoring/measuring apparatus and method |
| US6231597B1 (en) * | 1999-02-16 | 2001-05-15 | Mark E. Deem | Apparatus and methods for selectively stenting a portion of a vessel wall |
| US6217895B1 (en) * | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
| AU767526B2 (en) * | 1999-04-26 | 2003-11-13 | Gmp Vision Solutions, Inc. | Trabeculotomy device and method for treating glaucoma |
| US20050119601A9 (en) * | 1999-04-26 | 2005-06-02 | Lynch Mary G. | Shunt device and method for treating glaucoma |
| US6699210B2 (en) | 1999-04-27 | 2004-03-02 | The Arizona Board Of Regents | Glaucoma shunt and a method of making and surgically implanting the same |
| DE19920615A1 (de) | 1999-05-05 | 2000-12-07 | Tui Laser Ag | Vorrichtung zur Glaucornbehandlung des Auges |
| US6342058B1 (en) * | 1999-05-14 | 2002-01-29 | Valdemar Portney | Iris fixated intraocular lens and instrument for attaching same to an iris |
| US6558342B1 (en) | 1999-06-02 | 2003-05-06 | Optonol Ltd. | Flow control device, introducer and method of implanting |
| US6306132B1 (en) | 1999-06-17 | 2001-10-23 | Vivant Medical | Modular biopsy and microwave ablation needle delivery apparatus adapted to in situ assembly and method of use |
| US6221078B1 (en) | 1999-06-25 | 2001-04-24 | Stephen S. Bylsma | Surgical implantation apparatus |
| US20080277007A1 (en) | 1999-06-28 | 2008-11-13 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US7144616B1 (en) | 1999-06-28 | 2006-12-05 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US8550119B2 (en) | 1999-06-28 | 2013-10-08 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| IL147302A0 (en) | 1999-06-28 | 2002-08-14 | California Inst Of Techn | Microfabricated elastomeric valve and pump systems |
| US6899137B2 (en) | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US6201001B1 (en) | 1999-08-02 | 2001-03-13 | Abbott Laboratories | Imidazole antiproliferative agents |
| US7033603B2 (en) * | 1999-08-06 | 2006-04-25 | Board Of Regents The University Of Texas | Drug releasing biodegradable fiber for delivery of therapeutics |
| WO2001013832A1 (en) | 1999-08-23 | 2001-03-01 | Conceptus, Inc. | Insertion/deployment catheter system for intrafallopian contraception |
| US6605053B1 (en) | 1999-09-10 | 2003-08-12 | Percardia, Inc. | Conduit designs and related methods for optimal flow control |
| US6187016B1 (en) * | 1999-09-14 | 2001-02-13 | Daniel G. Hedges | Stent retrieval device |
| US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
| ATE283013T1 (de) | 1999-10-21 | 2004-12-15 | Alcon Inc | Medikamentenzuführvorrichtung |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| US6579235B1 (en) * | 1999-11-01 | 2003-06-17 | The Johns Hopkins University | Method for monitoring intraocular pressure using a passive intraocular pressure sensor and patient worn monitoring recorder |
| US7758624B2 (en) | 2000-11-13 | 2010-07-20 | C. R. Bard, Inc. | Implant delivery device |
| US6287313B1 (en) | 1999-11-23 | 2001-09-11 | Sdgi Holdings, Inc. | Screw delivery system and method |
| AU776599B2 (en) | 1999-11-24 | 2004-09-16 | Grieshaber & Co. Ag | Device for improving the aqueous humour outflow in the eye of a living thing |
| DE29920949U1 (de) | 1999-11-29 | 2000-04-27 | Bugge, Mogens, Göteborg | Saugrohr für chirurgische Zwecke |
| KR100769224B1 (ko) | 1999-12-10 | 2007-10-22 | 아이싸이언스 인터벤셔날 코포레이션 | 안 질환의 치료방법 |
| US6450937B1 (en) * | 1999-12-17 | 2002-09-17 | C. R. Bard, Inc. | Needle for implanting brachytherapy seeds |
| AU2626601A (en) | 2000-01-03 | 2001-07-16 | Johns Hopkins University, The | Device and method for manual retinal vein catheterization |
| WO2001049183A1 (en) | 2000-01-03 | 2001-07-12 | Johns Hopkins University | Intraoperative microsurgical ultrasonic device and methods |
| US6726676B2 (en) | 2000-01-05 | 2004-04-27 | Grieshaber & Co. Ag Schaffhausen | Method of and device for improving the flow of aqueous humor within the eye |
| US20050119737A1 (en) | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
| US20030212383A1 (en) | 2001-01-05 | 2003-11-13 | Dana Cote | System and methods for reducing intraocular pressure |
| BR0107591A (pt) | 2000-01-12 | 2004-07-27 | Becton Dickinson Co | Sistemas e processos para reduzir a pressão intraocular |
| US6589203B1 (en) * | 2000-01-26 | 2003-07-08 | Peter Mitrev | Glaucoma drainage device implant |
| US6375642B1 (en) * | 2000-02-15 | 2002-04-23 | Grieshaber & Co. Ag Schaffhausen | Method of and device for improving a drainage of aqueous humor within the eye |
| US6471666B1 (en) * | 2000-02-24 | 2002-10-29 | Steven A. Odrich | Injectable glaucoma device |
| US6623283B1 (en) | 2000-03-08 | 2003-09-23 | Autosplice, Inc. | Connector with base having channels to facilitate surface mount solder attachment |
| US7077848B1 (en) | 2000-03-11 | 2006-07-18 | John Hopkins University | Sutureless occular surgical methods and instruments for use in such methods |
| US6613343B2 (en) | 2000-04-12 | 2003-09-02 | Pharmacia Groningen Bv | Injectable intraocular accommodating lens |
| US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
| US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
| US20050049578A1 (en) * | 2000-04-14 | 2005-03-03 | Hosheng Tu | Implantable ocular pump to reduce intraocular pressure |
| US6533768B1 (en) * | 2000-04-14 | 2003-03-18 | The Regents Of The University Of California | Device for glaucoma treatment and methods thereof |
| US20030060752A1 (en) * | 2000-04-14 | 2003-03-27 | Olav Bergheim | Glaucoma device and methods thereof |
| US20050277864A1 (en) | 2000-04-14 | 2005-12-15 | David Haffner | Injectable gel implant for glaucoma treatment |
| US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
| US20020143284A1 (en) | 2001-04-03 | 2002-10-03 | Hosheng Tu | Drug-releasing trabecular implant for glaucoma treatment |
| US20040111050A1 (en) | 2000-04-14 | 2004-06-10 | Gregory Smedley | Implantable ocular pump to reduce intraocular pressure |
| GB0010871D0 (en) | 2000-05-06 | 2000-06-28 | Duckworth & Kent Ltd | Opthalmic injector |
| ATE464031T1 (de) | 2000-05-08 | 2010-04-15 | Optima Ltd I | Nicht penetrierende filtrationschirurgie |
| US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
| DE60131273T2 (de) * | 2000-05-19 | 2008-08-28 | Michael S. Beverly Hills Berlin | Laserapplikationssystem und methode zur verwendung im auge |
| US8679089B2 (en) | 2001-05-21 | 2014-03-25 | Michael S. Berlin | Glaucoma surgery methods and systems |
| US6561974B1 (en) | 2000-05-31 | 2003-05-13 | Grieshaber & Co. Ag Schaffhausen | Device for use in a surgical procedure on an eye of a living being, and method of retracting the iris |
| AU2001268253A1 (en) | 2000-06-19 | 2002-01-02 | Glaukos Corporation | Stented trabecular shunt and methods thereof |
| US6582453B1 (en) | 2000-07-14 | 2003-06-24 | Opus Medical, Inc. | Method and apparatus for attaching connective tissues to bone using a suture anchoring device |
| US6629992B2 (en) | 2000-08-04 | 2003-10-07 | Advanced Cardiovascular Systems, Inc. | Sheath for self-expanding stent |
| US6699211B2 (en) * | 2000-08-22 | 2004-03-02 | James A. Savage | Method and apparatus for treatment of glaucoma |
| FR2813521B1 (fr) | 2000-09-01 | 2003-06-13 | Ioltechnologie Production | Drain a glaucome |
| US6428501B1 (en) | 2000-09-19 | 2002-08-06 | K2 Limited Partnership U/A/D | Surgical instrument sleeve |
| US6730056B1 (en) * | 2000-09-21 | 2004-05-04 | Motorola, Inc. | Eye implant for treating glaucoma and method for manufacturing same |
| US6962573B1 (en) | 2000-10-18 | 2005-11-08 | Wilcox Michael J | C-shaped cross section tubular ophthalmic implant for reduction of intraocular pressure in glaucomatous eyes and method of use |
| US6428566B1 (en) | 2000-10-31 | 2002-08-06 | Advanced Cardiovascular Systems, Inc. | Flexible hoop and link sheath for a stent delivery system |
| AU2001261262A1 (en) | 2000-11-01 | 2002-05-15 | Glaukos Corporation | Glaucoma treatment device |
| FR2817912B1 (fr) | 2000-12-07 | 2003-01-17 | Hispano Suiza Sa | Reducteur reprenant les efforts axiaux generes par la soufflante d'un turboreacteur |
| DE10062478A1 (de) | 2000-12-14 | 2002-07-04 | Glautec Ag | Vorrichtung zur Glaukombehandlung |
| US6544208B2 (en) | 2000-12-29 | 2003-04-08 | C. Ross Ethier | Implantable shunt device |
| US6881198B2 (en) | 2001-01-09 | 2005-04-19 | J. David Brown | Glaucoma treatment device and method |
| US6595945B2 (en) | 2001-01-09 | 2003-07-22 | J. David Brown | Glaucoma treatment device and method |
| EP1351600A1 (de) | 2001-01-17 | 2003-10-15 | Humanoptics AG | Implantat zur bestimmung des augeninnendrucks |
| IL156831A0 (en) | 2001-01-18 | 2004-02-08 | Univ California | Minimally invasive glaucoma surgical instrument and method |
| US6827738B2 (en) | 2001-01-30 | 2004-12-07 | Timothy R. Willis | Refractive intraocular implant lens and method |
| ATE337766T1 (de) | 2001-02-23 | 2006-09-15 | Refocus Ocular Inc | Schneidegerät für sklerotikaimplantate |
| ATE492293T1 (de) | 2001-02-27 | 2011-01-15 | Senju Pharma Co | Arzneimittelfreisetzungssystem aus einem biologisch abbaubaren polymer |
| EP1367968A4 (en) | 2001-03-16 | 2006-12-13 | Glaukos Corp | APPLICATOR AND METHOD FOR SETTING A TRABECULAR SHUNT FOR GLUCKOM TREATMENT |
| US6585753B2 (en) * | 2001-03-28 | 2003-07-01 | Scimed Life Systems, Inc. | Expandable coil stent |
| US6981958B1 (en) | 2001-05-02 | 2006-01-03 | Glaukos Corporation | Implant with pressure sensor for glaucoma treatment |
| US6666841B2 (en) | 2001-05-02 | 2003-12-23 | Glaukos Corporation | Bifurcatable trabecular shunt for glaucoma treatment |
| AU2002258754B2 (en) | 2001-04-07 | 2006-08-17 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| US7488303B1 (en) | 2002-09-21 | 2009-02-10 | Glaukos Corporation | Ocular implant with anchor and multiple openings |
| DE10118933A1 (de) | 2001-04-18 | 2002-11-14 | Glautec Ag | Vorrichtung zur Glaukombehandlung |
| AT409586B (de) | 2001-04-26 | 2002-09-25 | Clemens Dr Vass | Drainageimplantat zur ableitung von kammerwasser aus der vorderen augenkammer in den schlemm'schen kanal |
| AU2002347269A1 (en) | 2001-05-01 | 2003-01-02 | Glaukos Corporation | Glaucoma device and methods thereof |
| US7678065B2 (en) | 2001-05-02 | 2010-03-16 | Glaukos Corporation | Implant with intraocular pressure sensor for glaucoma treatment |
| US6533769B2 (en) | 2001-05-03 | 2003-03-18 | Holmen Joergen | Method for use in cataract surgery |
| WO2002089699A2 (en) | 2001-05-03 | 2002-11-14 | Glaukos Corporation | Medical device and methods of use for glaucoma treatment |
| DE10127666A1 (de) | 2001-06-07 | 2003-01-09 | Glautec Ag | Vorrichtung zur Glaukombehandlung |
| US8267995B2 (en) | 2001-08-03 | 2012-09-18 | David Castillejos | Method and intra sclera implant for treatment of glaucoma and presbyopia |
| RU2197206C1 (ru) | 2001-08-15 | 2003-01-27 | Свадовский Александр Игоревич | Способ лечения глаукомы |
| EP1416985A2 (en) | 2001-08-16 | 2004-05-12 | Gmp Vision Solutions, Inc. | Improved shunt device and method for treating glaucoma |
| US7331984B2 (en) | 2001-08-28 | 2008-02-19 | Glaukos Corporation | Glaucoma stent for treating glaucoma and methods of use |
| IN2014DN10834A (https=) | 2001-09-17 | 2015-09-04 | Psivida Inc | |
| US6767346B2 (en) | 2001-09-20 | 2004-07-27 | Endocare, Inc. | Cryosurgical probe with bellows shaft |
| US20030097151A1 (en) * | 2001-10-25 | 2003-05-22 | Smedley Gregory T. | Apparatus and mitochondrial treatment for glaucoma |
| US7163543B2 (en) * | 2001-11-08 | 2007-01-16 | Glaukos Corporation | Combined treatment for cataract and glaucoma treatment |
| US20030093084A1 (en) | 2001-11-13 | 2003-05-15 | Optonol Ltd. | Delivery devices for flow regulating implants |
| IL161936A0 (en) | 2001-11-15 | 2005-11-20 | Optotech Ltd | Non-penetrating filtration surgery |
| US6802829B2 (en) | 2001-11-16 | 2004-10-12 | Infinite Vision, Llc | Spray device |
| CA2466835A1 (en) | 2001-11-21 | 2003-06-05 | Stanley R. Conston | Ophthalmic microsurgical system |
| DE50214560D1 (de) | 2001-11-22 | 2010-09-09 | Eduard Anton Haefliger | Vorrichtung und Verfahren zur Durchführung opthalmologischer Eingriffe |
| US20030105456A1 (en) | 2001-12-04 | 2003-06-05 | J.T. Lin | Apparatus and methods for prevention of age-related macular degeneration and other eye diseases |
| US6893413B2 (en) | 2002-01-07 | 2005-05-17 | Eric C. Martin | Two-piece stent combination for percutaneous arterialization of the coronary sinus and retrograde perfusion of the myocardium |
| US6966888B2 (en) | 2002-01-13 | 2005-11-22 | Eagle Vision, Inc. | Sinus valved glaucoma shunt |
| US20030153863A1 (en) | 2002-02-13 | 2003-08-14 | Patel Anilbhai S. | Implant system for glaucoma surgery |
| WO2003073968A2 (en) | 2002-02-28 | 2003-09-12 | Gmp Vision Solutions, Inc. | Device and method for monitoring aqueous flow within the eye |
| US20060200113A1 (en) | 2002-03-07 | 2006-09-07 | David Haffner | Liquid jet for glaucoma treatment |
| US7186232B1 (en) | 2002-03-07 | 2007-03-06 | Glaukoa Corporation | Fluid infusion methods for glaucoma treatment |
| US7951155B2 (en) | 2002-03-15 | 2011-05-31 | Glaukos Corporation | Combined treatment for cataract and glaucoma treatment |
| US20030229303A1 (en) | 2002-03-22 | 2003-12-11 | Haffner David S. | Expandable glaucoma implant and methods of use |
| US6902577B2 (en) | 2002-03-29 | 2005-06-07 | Isaac Lipshitz | Intraocular lens implant with mirror |
| US20040147870A1 (en) | 2002-04-08 | 2004-07-29 | Burns Thomas W. | Glaucoma treatment kit |
| US9301875B2 (en) | 2002-04-08 | 2016-04-05 | Glaukos Corporation | Ocular disorder treatment implants with multiple opening |
| US20030195438A1 (en) | 2002-04-12 | 2003-10-16 | Petillo Phillip J. | Method and apparatus to treat glaucoma |
| US20040024345A1 (en) * | 2002-04-19 | 2004-02-05 | Morteza Gharib | Glaucoma implant with valveless flow bias |
| US7041114B2 (en) | 2002-05-01 | 2006-05-09 | D.O.T. Dan Ophthalmic Technologies Ltd. | Surgical tool and method for extracting tissue from wall of an organ |
| ATE518499T1 (de) | 2002-05-20 | 2011-08-15 | Refocus Group Inc | System und verfahren zur bestimmung einer position für eine skleratasche für eine skleraprothese |
| US20050273033A1 (en) | 2002-05-29 | 2005-12-08 | Grahn Bruce H | Shunt and method treatment of glaucoma |
| ES2279156T3 (es) | 2002-06-11 | 2007-08-16 | Tyco Healthcare Group Lp | Tachuelas de mallas para hernias. |
| US20040243227A1 (en) | 2002-06-13 | 2004-12-02 | Guided Delivery Systems, Inc. | Delivery devices and methods for heart valve repair |
| US20030236483A1 (en) * | 2002-06-25 | 2003-12-25 | Ren David H | Dual drainage ocular shunt for glaucoma |
| US20070219632A1 (en) | 2002-08-02 | 2007-09-20 | David Castillejos | Method and intra-sclera implant for treatment of glaucoma and presbyopia |
| US7192412B1 (en) | 2002-09-14 | 2007-03-20 | Glaukos Corporation | Targeted stent placement and multi-stent therapy |
| EP1539066B1 (en) | 2002-09-17 | 2012-11-07 | Iscience Surgical Corporation | Apparatus surgical bypass of aqueous humor |
| US7468065B2 (en) | 2002-09-18 | 2008-12-23 | Allergan, Inc. | Apparatus for delivery of ocular implants |
| KR20050047118A (ko) | 2002-09-18 | 2005-05-19 | 알러간, 인코포레이티드 | 안과 임플란트의 수송을 위한 방법 및 장치 |
| US7192484B2 (en) | 2002-09-27 | 2007-03-20 | Surmodics, Inc. | Advanced coating apparatus and method |
| USRE40722E1 (en) | 2002-09-27 | 2009-06-09 | Surmodics, Inc. | Method and apparatus for coating of substrates |
| US7001426B2 (en) | 2002-11-18 | 2006-02-21 | The Institute For Eye Research | One-piece minicapsulorhexis valve |
| US20040102832A1 (en) * | 2002-11-21 | 2004-05-27 | Doty David R. | Stent delivery and retention apparatus |
| US7160264B2 (en) | 2002-12-19 | 2007-01-09 | Medtronic-Xomed, Inc. | Article and method for ocular aqueous drainage |
| US7544368B2 (en) | 2002-12-20 | 2009-06-09 | Life Spring Biotech Co., Ltd. | Structure for modulating intraocular pressure |
| JP2004208898A (ja) | 2002-12-27 | 2004-07-29 | Japan Science & Technology Agency | 緑内障治療用房水排出インプラント |
| US20040162545A1 (en) | 2003-02-14 | 2004-08-19 | Brown J. David | Bypass for glaucoma drainage device |
| US7354416B2 (en) | 2003-02-18 | 2008-04-08 | Hugo Quiroz-Mercado | Methods and devices for draining fluids and lowering intraocular pressure |
| US8012115B2 (en) | 2003-02-18 | 2011-09-06 | S.K. Pharmaceuticals, Inc. | Optic nerve implants |
| US7297154B2 (en) | 2003-02-24 | 2007-11-20 | Maxwell Sensors Inc. | Optical apparatus for detecting and treating vulnerable plaque |
| USD490152S1 (en) * | 2003-02-28 | 2004-05-18 | Glaukos Corporation | Surgical handpiece |
| US20050209672A1 (en) | 2004-03-02 | 2005-09-22 | Cardiomind, Inc. | Sliding restraint stent delivery systems |
| US20040193262A1 (en) * | 2003-03-29 | 2004-09-30 | Shadduck John H. | Implants for treating ocular hypertension, methods of use and methods of fabrication |
| US20040193095A1 (en) | 2003-03-29 | 2004-09-30 | Shadduck John H. | Implants for treating ocular hypertension, methods of use and methods of fabrication |
| ATE439107T1 (de) | 2003-04-16 | 2009-08-15 | Iscience Interventional Corp | Mikrochirurgische instrumente für die ophthalmologie |
| US20050038498A1 (en) | 2003-04-17 | 2005-02-17 | Nanosys, Inc. | Medical device applications of nanostructured surfaces |
| US7025740B2 (en) | 2003-04-22 | 2006-04-11 | Ahmed A Mateen | Device for treating glaucoma & method of manufacture |
| US20040236343A1 (en) | 2003-05-23 | 2004-11-25 | Taylor Jon B. | Insertion tool for ocular implant and method for using same |
| JP4611309B2 (ja) | 2003-06-10 | 2011-01-12 | ネオメディックス コーポレイション | 患者の体から組織片を切り取るための管状の切除装置及びその方法 |
| CA2528060C (en) | 2003-06-10 | 2012-12-11 | Microsurgical Technology, Inc. | Device and methods useable for treatment of glaucoma and other surgical procedures |
| EP2298184A1 (en) | 2003-06-13 | 2011-03-23 | Tyco Healthcare Group LP | Multiple member interconnect for surgical instrument and absorbable screw fastener |
| CA2529495C (en) | 2003-06-16 | 2013-02-05 | Solx, Inc. | Shunt for the treatment of glaucoma |
| US20050055075A1 (en) | 2003-09-08 | 2005-03-10 | Leonard Pinchuk | Methods for the manufacture of porous prostheses |
| ES2449496T3 (es) | 2003-12-05 | 2014-03-20 | Innfocus, Inc. | Dispositivo mejorado de implante para glaucoma |
| DE602004024577D1 (de) | 2003-12-15 | 2010-01-21 | Terumo Corp | Katheteranordnung |
| KR20060130648A (ko) | 2004-01-12 | 2006-12-19 | 아이싸이언스 인터벤셔날 코포레이션 | 점성 물질용 인젝터 |
| AU2005208820A1 (en) | 2004-01-22 | 2005-08-11 | Solx, Inc. | Glaucoma treatment method |
| DK1715827T3 (da) | 2004-01-23 | 2011-04-18 | Iscience Interventional Corp | Sammensat ophthalmisk mikrokanyle |
| US20050250788A1 (en) | 2004-01-30 | 2005-11-10 | Hosheng Tu | Aqueous outflow enhancement with vasodilated aqueous cavity |
| US20060036207A1 (en) | 2004-02-24 | 2006-02-16 | Koonmen James P | System and method for treating glaucoma |
| US7544176B2 (en) | 2005-06-21 | 2009-06-09 | Becton, Dickinson And Company | Glaucoma implant having MEMS flow module with flexing diaphragm for pressure regulation |
| US7384550B2 (en) | 2004-02-24 | 2008-06-10 | Becton, Dickinson And Company | Glaucoma implant having MEMS filter module |
| US7364564B2 (en) | 2004-03-02 | 2008-04-29 | Becton, Dickinson And Company | Implant having MEMS flow module with movable, flow-controlling baffle |
| US7803150B2 (en) | 2004-04-21 | 2010-09-28 | Acclarent, Inc. | Devices, systems and methods useable for treating sinusitis |
| US7156821B2 (en) | 2004-04-23 | 2007-01-02 | Massachusetts Eye & Ear Infirmary | Shunt with enclosed pressure-relief valve |
| US7758612B2 (en) | 2004-04-27 | 2010-07-20 | Tyco Healthcare Group Lp | Surgery delivery device and mesh anchor |
| US8114099B2 (en) | 2004-04-27 | 2012-02-14 | Tyco Healthcare Group Lp | Absorbable anchor for hernia mesh fixation |
| US20080058704A1 (en) | 2004-04-29 | 2008-03-06 | Michael Hee | Apparatus and Method for Ocular Treatment |
| ZA200609408B (en) | 2004-04-29 | 2008-02-27 | Iscience Interventional Corp | Apparatus and method for surgical enhancement of aqueous humor drainage |
| CN101052434A (zh) | 2004-04-29 | 2007-10-10 | I科学干预公司 | 用于治疗眼睛的装置和方法 |
| US20100173866A1 (en) | 2004-04-29 | 2010-07-08 | Iscience Interventional Corporation | Apparatus and method for ocular treatment |
| US8673341B2 (en) | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
| US20070179426A1 (en) | 2004-05-11 | 2007-08-02 | Selden Nathan R | Interfacial stent and method of maintaining patency of surgical fenestrations |
| US7357778B2 (en) | 2004-05-20 | 2008-04-15 | Ajay Bhalla | Aqueous drainage and flow regulating implant |
| US20050267398A1 (en) | 2004-05-27 | 2005-12-01 | Dimitri Protopsaltis | Glaucoma shunt |
| US20060293612A1 (en) | 2004-06-24 | 2006-12-28 | Boston Scientific Scimed, Inc. | Apparatus and method for treating occluded vasculature |
| US7862531B2 (en) | 2004-06-25 | 2011-01-04 | Optonol Ltd. | Flow regulating implants |
| US20060032507A1 (en) | 2004-08-11 | 2006-02-16 | Hosheng Tu | Contrast-enhanced ocular imaging |
| US8246569B1 (en) | 2004-08-17 | 2012-08-21 | California Institute Of Technology | Implantable intraocular pressure drain |
| US7905904B2 (en) | 2006-02-03 | 2011-03-15 | Biomet Sports Medicine, Llc | Soft tissue repair device and associated methods |
| US20060173397A1 (en) | 2004-11-23 | 2006-08-03 | Hosheng Tu | Ophthalmology implants and methods of manufacture |
| US7837644B2 (en) | 2004-12-03 | 2010-11-23 | Innfocus, Llc | Glaucoma implant device |
| US20070118065A1 (en) | 2004-12-03 | 2007-05-24 | Leonard Pinchuk | Glaucoma Implant Device |
| US7594899B2 (en) | 2004-12-03 | 2009-09-29 | Innfocus, Llc | Glaucoma implant device |
| US20060129129A1 (en) | 2004-12-10 | 2006-06-15 | Cloud Farm Associates, L.P. | Eye implant devices and method and device for implanting such devices for treatment of glaucoma |
| US20120010702A1 (en) | 2004-12-16 | 2012-01-12 | Iscience Interventional Corporation | Ophthalmic implant for treatment of glaucoma |
| EP2215996B1 (en) | 2004-12-16 | 2013-04-03 | Iscience Interventional Corporation | Ophthalmic implant for treatment of glaucoma |
| US7713228B2 (en) | 2005-01-28 | 2010-05-11 | Alcon, Inc. | Surgical method |
| AR054647A1 (es) | 2005-02-21 | 2007-07-11 | Maldonado Bas Arturo | Dispositivo para drenaje de humor acuoso en casos de glaucoma |
| US9186274B2 (en) | 2005-02-23 | 2015-11-17 | Camras Vision Inc. | Method and apparatus for reducing intraocular pressure |
| US7641627B2 (en) | 2005-02-23 | 2010-01-05 | Camras Carl B | Method and apparatus for reducing intraocular pressure |
| CA2598696A1 (en) | 2005-02-23 | 2006-08-31 | Surmodics, Inc. | Implantable medical articles having laminin coatings and methods of use |
| US20060217741A1 (en) | 2005-03-28 | 2006-09-28 | Ghannoum Ziad R | Irrigation tip |
| US20130079759A1 (en) | 2005-04-14 | 2013-03-28 | Robert S. Dotson | Ophthalmic Phototherapy Device and Associated Treatment Method |
| US20080269730A1 (en) | 2005-04-14 | 2008-10-30 | Dotson Robert S | Ophthalmic Phototherapy Device and Associated Treatment Method |
| WO2006122168A2 (en) | 2005-05-10 | 2006-11-16 | The Regents Of The University Of California | Self-clearing catheter for clinical implantation |
| JP4879897B2 (ja) | 2005-05-10 | 2012-02-22 | 卓也 片岡 | 眼科レーザー治療用器具 |
| US20070021653A1 (en) | 2005-06-27 | 2007-01-25 | Lars-Olof Hattenbach | Device for the injection of drugs into microvessels |
| US20090043365A1 (en) | 2005-07-18 | 2009-02-12 | Kolis Scientific, Inc. | Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma |
| US20080108932A1 (en) | 2005-08-24 | 2008-05-08 | Rodgers M Steven | MEMS filter module with multi-level filter traps |
| CA2621993A1 (en) | 2005-09-16 | 2007-03-29 | Bg Implant, Inc. | Glaucoma treatment devices and methods |
| US20070073390A1 (en) | 2005-09-23 | 2007-03-29 | Medlogics Device Corporation | Methods and devices for enhanced adhesion between metallic substrates and bioactive material-containing coatings |
| JP2009509650A (ja) | 2005-09-26 | 2009-03-12 | アテヌークス・テクノロジーズ・インコーポレーテッド | 圧力減衰デバイス |
| US7717872B2 (en) | 2005-09-28 | 2010-05-18 | Rajesh Kumar Shetty | Fluid shunting apparatus and methods |
| US7771388B2 (en) | 2005-10-12 | 2010-08-10 | Daniel Olsen | Steerable catheter system |
| US7655831B2 (en) | 2005-10-19 | 2010-02-02 | Prywes Arnold S | Method for fluid control in medical applications |
| US7959632B2 (en) | 2005-10-20 | 2011-06-14 | Fugo Richard J | Plasma incising device including disposable incising tips for performing surgical procedures |
| TW200733993A (en) | 2005-11-03 | 2007-09-16 | Reseal Internat Ltd Partnership | Continuously sealing one way valve assembly and fluid delivery system and formulations for use therein |
| US20070106200A1 (en) | 2005-11-08 | 2007-05-10 | Brian Levy | Intraocular shunt device and method |
| WO2007062306A2 (en) | 2005-11-18 | 2007-05-31 | The Board Of Regents Of The University Of Texas System | Methods for coating surfaces with antimicrobial agents |
| US20070161981A1 (en) | 2006-01-06 | 2007-07-12 | Arthrocare Corporation | Electrosurgical method and systems for treating glaucoma |
| EP3838236B1 (en) | 2006-01-17 | 2025-08-13 | Alcon Inc. | Glaucoma treatment device |
| US8585753B2 (en) | 2006-03-04 | 2013-11-19 | John James Scanlon | Fibrillated biodegradable prosthesis |
| EP1834636A1 (en) | 2006-03-08 | 2007-09-19 | Sahajanand Medical Technologies PVT. ltd | Compositions comprising porous articles and uses in implantable medical devices |
| CA2649721A1 (en) | 2006-04-18 | 2007-10-25 | Geoffrey B. Pardo | Intraocular pressure attenuation device |
| US7520876B2 (en) | 2006-04-21 | 2009-04-21 | Entellus Medical, Inc. | Device and method for treatment of sinusitis |
| US20080039931A1 (en) | 2006-04-25 | 2008-02-14 | Surmodics, Inc. | Hydrophilic shape memory insertable medical articles |
| EP2015671B1 (en) | 2006-04-26 | 2012-09-05 | Eastern Virginia Medical School | Systems for monitoring and controlling internal pressure of an eye or body part |
| US20070293807A1 (en) | 2006-05-01 | 2007-12-20 | Lynch Mary G | Dual drainage pathway shunt device and method for treating glaucoma |
| US7918814B2 (en) | 2006-05-02 | 2011-04-05 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
| US20070292470A1 (en) | 2006-06-15 | 2007-12-20 | Medtronic Vascular, Inc. | Implantable Medical Devices and Methods for Making the Same |
| US20070293873A1 (en) | 2006-06-19 | 2007-12-20 | Allergan, Inc. | Apparatus and methods for implanting particulate ocular implants |
| US8668676B2 (en) | 2006-06-19 | 2014-03-11 | Allergan, Inc. | Apparatus and methods for implanting particulate ocular implants |
| US7458953B2 (en) | 2006-06-20 | 2008-12-02 | Gholam A. Peyman | Ocular drainage device |
| US7909789B2 (en) | 2006-06-26 | 2011-03-22 | Sight Sciences, Inc. | Intraocular implants and methods and kits therefor |
| US8721702B2 (en) | 2010-11-15 | 2014-05-13 | Aquesys, Inc. | Intraocular shunt deployment devices |
| JP5396272B2 (ja) | 2006-06-30 | 2014-01-22 | アクエシス インコーポレイテッド | 臓器内圧力軽減のための方法、システムおよび装置 |
| US8663303B2 (en) | 2010-11-15 | 2014-03-04 | Aquesys, Inc. | Methods for deploying an intraocular shunt from a deployment device and into an eye |
| US20120197175A1 (en) | 2006-06-30 | 2012-08-02 | Aquesys, Inc. | Methods, systems and apparatus for relieving pressure in an organ |
| US8852137B2 (en) | 2010-11-15 | 2014-10-07 | Aquesys, Inc. | Methods for implanting a soft gel shunt in the suprachoroidal space |
| US8758290B2 (en) | 2010-11-15 | 2014-06-24 | Aquesys, Inc. | Devices and methods for implanting a shunt in the suprachoroidal space |
| AU2007273119A1 (en) | 2006-07-07 | 2008-01-17 | Surmodics, Inc. | Implantable medical articles having pro-healing coatings |
| CA2658168C (en) | 2006-07-11 | 2015-06-30 | Refocus Group, Inc. | Apparatus and method for securing ocular tissue |
| US9039761B2 (en) | 2006-08-04 | 2015-05-26 | Allergan, Inc. | Ocular implant delivery assemblies with distal caps |
| JP4977758B2 (ja) | 2006-08-10 | 2012-07-18 | カリフォルニア インスティテュート オブ テクノロジー | 自由な浮動部材を有するマイクロ流体バルブ及びその製造方法 |
| US20100262174A1 (en) | 2006-08-11 | 2010-10-14 | The Regents Of The University Of California | Microsurgery for Treatment of Glaucoma |
| US8043235B2 (en) | 2006-08-22 | 2011-10-25 | Schwartz Donald N | Ultrasonic treatment of glaucoma |
| CA2661352A1 (en) | 2006-08-22 | 2008-02-28 | Donald N. Schwartz | Ultrasonic treatment of glaucoma |
| US20080097214A1 (en) | 2006-09-05 | 2008-04-24 | Capistrano Labs, Inc. | Ophthalmic ultrasound probe assembly |
| EP2059282A4 (en) | 2006-09-06 | 2014-04-09 | Innfocus Inc | APPARATUS, METHODS AND DEVICES FOR THE TREATMENT OF OCULAR DISORDERS |
| US20080109037A1 (en) | 2006-11-03 | 2008-05-08 | Musculoskeletal Transplant Foundation | Press fit suture anchor and inserter assembly |
| US20080147083A1 (en) | 2006-11-09 | 2008-06-19 | Vold Steven D | Method and device for fixation of ophthalmic tissue |
| WO2008061043A2 (en) | 2006-11-10 | 2008-05-22 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
| US20080114440A1 (en) | 2006-11-13 | 2008-05-15 | Sage Medical Technologies, Inc | Methods and devices for deploying an implant in curved anatomy |
| FR2909883B1 (fr) | 2006-12-18 | 2012-11-30 | Commissariat Energie Atomique | Sonde a bras multiples et systeme pour neurostimulation electrique profonde comportant une telle sonde |
| AR058947A1 (es) | 2007-01-08 | 2008-03-05 | Consejo Nac Invest Cient Tec | Microaparato implantable en el ojo para aliviar glaucoma o enfermedad causante de sobrepresion ocular |
| US20080200923A1 (en) | 2007-01-09 | 2008-08-21 | Richard Beckman | Insertion tool for ocular implant and method for using same |
| CA2674891C (en) | 2007-01-09 | 2016-03-15 | Fovea Pharmaceuticals | Apparatus for intra-ocular injection |
| DE102007004906A1 (de) | 2007-01-25 | 2008-07-31 | Universität Rostock | Augenimplantat |
| US8066768B2 (en) | 2007-01-29 | 2011-11-29 | Werblin Research & Development Corp. | Intraocular lens system |
| US20080188860A1 (en) | 2007-02-07 | 2008-08-07 | Vold Steven D | Ophthalmic surgical apparatus |
| EP2764846A1 (en) | 2007-02-08 | 2014-08-13 | Kaneka Corporation | Injector for eye |
| USD606190S1 (en) | 2007-02-08 | 2009-12-15 | Aderans Research Institute, Inc. | Device for delivering cellular material and physiologic fluids to a subject |
| WO2008106421A2 (en) | 2007-02-27 | 2008-09-04 | Ast Products, Inc. | Instrument for injecting an ophthalmic device into an eye |
| WO2008112935A1 (en) | 2007-03-13 | 2008-09-18 | University Of Rochester | Intraocular pressure regulating device |
| US20080243247A1 (en) | 2007-03-26 | 2008-10-02 | Poley Brooks J | Method and apparatus for prevention and treatment of adult glaucoma |
| US20080243156A1 (en) | 2007-03-30 | 2008-10-02 | Thomas John | Ophthalmic surgical instrument & surgical methods |
| US20080255545A1 (en) | 2007-04-10 | 2008-10-16 | Mansfield John M | Apparatus and method for treating the inside of an eye |
| US7931660B2 (en) | 2007-05-10 | 2011-04-26 | Tyco Healthcare Group Lp | Powered tacker instrument |
| US20080306429A1 (en) | 2007-06-07 | 2008-12-11 | Shields Milton B | Uveoscleral drainage device |
| US8197418B2 (en) | 2007-06-08 | 2012-06-12 | Cornell University | Microprobes |
| WO2009012406A1 (en) | 2007-07-17 | 2009-01-22 | Transcend Medical, Inc. | Ocular implant with hydrogel expansion capabilities reference to priority document |
| US20090043242A1 (en) | 2007-08-07 | 2009-02-12 | Becton, Dickinson And Company | Instruments and methods for implanting corneal implant via extra-and intra-cameral routes |
| US8734377B2 (en) | 2007-09-24 | 2014-05-27 | Ivantis, Inc. | Ocular implants with asymmetric flexibility |
| US7740604B2 (en) | 2007-09-24 | 2010-06-22 | Ivantis, Inc. | Ocular implants for placement in schlemm's canal |
| US20090082862A1 (en) | 2007-09-24 | 2009-03-26 | Schieber Andrew T | Ocular Implant Architectures |
| US8945103B2 (en) | 2007-10-30 | 2015-02-03 | Iridex Corporation | Contact probe for the delivery of laser energy |
| US8083759B2 (en) | 2007-11-02 | 2011-12-27 | Refocus Ocular, Inc. | Apparatuses and methods for forming incisions in ocular tissue |
| US20090177138A1 (en) | 2007-11-07 | 2009-07-09 | Brown Reay H | Shunt Device for Glaucoma Treatment |
| USD592746S1 (en) | 2007-11-08 | 2009-05-19 | Alimera Sciences | Ocular implantation device |
| US9849027B2 (en) | 2007-11-08 | 2017-12-26 | Alimera Sciences, Inc. | Ocular implantation device |
| US20090124973A1 (en) | 2007-11-09 | 2009-05-14 | D Agostino Eduardo | Insertion mechanism for use with a syringe |
| US8512404B2 (en) | 2007-11-20 | 2013-08-20 | Ivantis, Inc. | Ocular implant delivery system and method |
| EP2417946A1 (en) | 2007-11-23 | 2012-02-15 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Non-invasively adjustable drainage device |
| US20090137992A1 (en) | 2007-11-27 | 2009-05-28 | Ravi Nallakrishnan | Apparatus and Method for Treating Glaucoma |
| DK2227257T3 (da) | 2008-01-07 | 2013-09-30 | Salutaris Medical Devices Inc | Anordninger til minimal-invasiv ekstraokular afgivelse af stråling til den posteriore del af øjet |
| US9539138B2 (en) | 2008-01-30 | 2017-01-10 | Takaya TANAKA | Method of ophthalmic surgery and kit therefor |
| US8109896B2 (en) | 2008-02-11 | 2012-02-07 | Optonol Ltd. | Devices and methods for opening fluid passageways |
| JP2011513002A (ja) | 2008-03-05 | 2011-04-28 | イバンティス インコーポレイテッド | 緑内障を治療する方法及び器具 |
| US20110082385A1 (en) | 2008-04-17 | 2011-04-07 | Yale University | Method for implanting intraocular pressure sensor |
| US20090287233A1 (en) | 2008-05-15 | 2009-11-19 | Huculak John C | Small Gauge Mechanical Tissue Cutter/Aspirator Probe For Glaucoma Surgery |
| CN103584948B (zh) | 2008-05-15 | 2016-06-01 | 脉诺斯细胞器械公司 | 用于囊切开术的眼外科手术设备 |
| US8157759B2 (en) | 2008-05-16 | 2012-04-17 | Ocumatrix, Inc. | Method and apparatus for fluid drainage of the eye |
| EP2334268B1 (en) | 2008-06-25 | 2017-08-02 | Novartis Ag | Ocular implant with shape change capabilities |
| US8628492B2 (en) | 2008-07-01 | 2014-01-14 | California Institute Of Technology | Implantable glaucoma drainage device |
| US20100056977A1 (en) | 2008-08-26 | 2010-03-04 | Thaddeus Wandel | Trans-corneal shunt and method |
| EP2180322A1 (en) | 2008-10-22 | 2010-04-28 | BRAHMS Aktiengesellschaft | Prognostic biomarkers for the progression of primary chronic kidney disease |
| US8353856B2 (en) | 2008-11-05 | 2013-01-15 | Abbott Medical Optics Inc. | Glaucoma drainage shunts and methods of use |
| US7695135B1 (en) | 2008-11-11 | 2010-04-13 | Boston Foundation For Sight | Scleral lens with scalloped channels or circumferential fenestrated channels |
| US8079972B2 (en) | 2008-11-20 | 2011-12-20 | Schocket Stanley S | Implant for use in surgery for glaucoma and a method |
| JP5520962B2 (ja) | 2008-12-05 | 2014-06-11 | イバンティス インコーポレイテッド | 眼内インプラントを眼球内に送出するための装置 |
| US20100158980A1 (en) | 2008-12-18 | 2010-06-24 | Casey Kopczynski | Drug delivery devices for delivery of therapeutic agents |
| CH700161A2 (de) | 2008-12-22 | 2010-06-30 | Grieshaber Ophthalmic Res Foun | Implantat zum einführen in den schlemmschen kanal eines auges. |
| US8545554B2 (en) | 2009-01-16 | 2013-10-01 | Allergan, Inc. | Intraocular injector |
| ES2817775T3 (es) | 2009-01-28 | 2021-04-08 | Alcon Inc | Implante ocular con calidades de rigidez |
| US8399006B2 (en) | 2009-01-29 | 2013-03-19 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| WO2010093945A2 (en) | 2009-02-13 | 2010-08-19 | Glaukos Corporation | Uveoscleral drug delivery implant and methods for implanting the same |
| US20100225061A1 (en) | 2009-03-09 | 2010-09-09 | Bath David L | System and method for gaming with an engagable projectile |
| US8702639B2 (en) | 2009-03-26 | 2014-04-22 | Abbott Medical Optics Inc. | Glaucoma shunts with flow management and improved surgical performance |
| WO2010115101A1 (en) | 2009-04-03 | 2010-10-07 | Transcend Medical, Inc. | Ocular implant delivery systems and methods |
| CA3186189A1 (en) | 2009-05-18 | 2010-11-25 | Dose Medical Corporation | Drug eluting ocular implant |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| US8764696B2 (en) | 2009-06-16 | 2014-07-01 | Mobius Therapeutics, Inc. | Medical drainage devices with carbon-based structures for inhibiting growth of fibroblasts |
| AU2010271218B2 (en) | 2009-07-09 | 2017-02-02 | Alcon Inc. | Ocular implants and methods for delivering ocular implants into the eye |
| JP5726186B2 (ja) | 2009-07-09 | 2015-05-27 | イバンティス インコーポレイテッド | 眼内インプラントを送出するための単オペレータデバイス |
| US20120130467A1 (en) | 2009-07-24 | 2012-05-24 | Selden Nathan R | Interfacial stent and method of maintaining patency of surgical fenestrations |
| US8535333B2 (en) | 2009-07-29 | 2013-09-17 | Transcend Medical, Inc. | Ocular implant applier and methods of use |
| US20110118835A1 (en) | 2009-08-13 | 2011-05-19 | Matthew Silvestrini | Branched ocular implant |
| US8951221B2 (en) | 2009-08-20 | 2015-02-10 | Grieshaber Ophthalmic Research Foundation | Method and device for the treatment of glaucoma |
| US8257295B2 (en) | 2009-09-21 | 2012-09-04 | Alcon Research, Ltd. | Intraocular pressure sensor with external pressure compensation |
| US8721580B2 (en) | 2009-09-21 | 2014-05-13 | Alcon Research, Ltd. | Power saving glaucoma drainage device |
| US8545431B2 (en) | 2009-09-21 | 2013-10-01 | Alcon Research, Ltd. | Lumen clearing valve for glaucoma drainage device |
| US20110071454A1 (en) | 2009-09-21 | 2011-03-24 | Alcon Research, Ltd. | Power Generator For Glaucoma Drainage Device |
| US8419673B2 (en) | 2009-09-21 | 2013-04-16 | Alcon Research, Ltd. | Glaucoma drainage device with pump |
| US9119951B2 (en) | 2009-10-12 | 2015-09-01 | Kona Medical, Inc. | Energetic modulation of nerves |
| WO2011046949A2 (en) | 2009-10-12 | 2011-04-21 | The Regents Of The University Of Colorado, A Body Corporate | Implants for reducing intraocular pressure |
| JP2013508096A (ja) | 2009-10-23 | 2013-03-07 | イバンティス インコーポレイテッド | 眼内移植システムおよび眼内移植方法 |
| US8771216B2 (en) | 2009-11-06 | 2014-07-08 | University Hospitals Of Cleveland | Fluid communication device and method of use thereof |
| US8845572B2 (en) | 2009-11-13 | 2014-09-30 | Grieshaber Ophthalmic Research Foundation | Method and device for the treatment of glaucoma |
| US20110144641A1 (en) | 2009-12-15 | 2011-06-16 | Alcon Research, Ltd. | High-Intensity Pulsed Electric Field Vitrectomy Apparatus |
| WO2011097408A1 (en) | 2010-02-05 | 2011-08-11 | Sight Sciences, Inc | Intraocular implants and related kits and methods |
| US20110202049A1 (en) | 2010-02-18 | 2011-08-18 | Alcon Research, Ltd. | Small Gauge Ablation Probe For Glaucoma Surgery |
| US20110230877A1 (en) | 2010-03-16 | 2011-09-22 | Alcon Research, Ltd. | Pulsed Electric Field Probe for Glaucoma Surgery |
| US20110245753A1 (en) | 2010-04-05 | 2011-10-06 | Sunalp Murad A | Apparatus and method for lowering intraocular pressure in an eye |
| US20110248671A1 (en) | 2010-04-08 | 2011-10-13 | Alcon Research, Ltd. | Power System Implantable in Eye |
| WO2011127395A1 (en) | 2010-04-08 | 2011-10-13 | Healionics Corporation | Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same |
| PT2575715E (pt) | 2010-05-27 | 2014-12-22 | Ellex Iscience Inc | Dispositivo para colocar implante circunferencial em canal de schlem |
| US8545430B2 (en) | 2010-06-09 | 2013-10-01 | Transcend Medical, Inc. | Expandable ocular devices |
| US8444589B2 (en) | 2010-06-09 | 2013-05-21 | Transcend Medical, Inc. | Ocular implant with fluid outflow pathways having microporous membranes |
| WO2011163505A1 (en) | 2010-06-23 | 2011-12-29 | Ivantis, Inc. | Ocular implants deployed in schlemm's canal of the eye |
| US10576304B2 (en) | 2010-06-29 | 2020-03-03 | Sunnybrook Research Institute | Thermal therapy apparatus and method using focused ultrasonic sound fields |
| US8449490B2 (en) | 2010-09-11 | 2013-05-28 | Aleeva Medical Inc. | Disc shunt delivery with stepped needle |
| US8915877B2 (en) | 2010-10-12 | 2014-12-23 | Emmett T. Cunningham, JR. | Glaucoma drainage device and uses thereof |
| US9370444B2 (en) | 2010-10-12 | 2016-06-21 | Emmett T. Cunningham, JR. | Subconjunctival conformer device and uses thereof |
| US20120271272A1 (en) | 2010-10-15 | 2012-10-25 | Iscience Interventional Corporation | Device for ocular access |
| US8585629B2 (en) | 2010-11-15 | 2013-11-19 | Aquesys, Inc. | Systems for deploying intraocular shunts |
| US9668915B2 (en) | 2010-11-24 | 2017-06-06 | Dose Medical Corporation | Drug eluting ocular implant |
| US20120238994A1 (en) | 2010-12-22 | 2012-09-20 | Martin Nazzaro | Two-piece injectable drug delivery device with heat-cured seal |
| US9101445B2 (en) | 2011-01-14 | 2015-08-11 | Ecole Polytechnique Federale De Lausanne (Epfl) | Apparatus and methods for treating excess intraocular fluid |
| US10390856B2 (en) | 2011-01-18 | 2019-08-27 | Minipumps, Llc | Surgical implantation instrument |
| EP2517619B1 (en) | 2011-04-27 | 2013-05-22 | Istar Medical | Improvements in or relating to glaucoma management and treatment |
| US20120283557A1 (en) | 2011-05-05 | 2012-11-08 | Berlin Michael S | Methods and Apparatuses for the Treatment of Glaucoma using visible and infrared ultrashort laser pulses |
| US8747299B2 (en) | 2011-06-02 | 2014-06-10 | Grieshaber Ophtalmic Research Foundation | Method and device for the pathology analysis of the Schlemm's canal |
| WO2012167167A2 (en) | 2011-06-02 | 2012-12-06 | Silvestrini Thomas A | Eye shunt with porous structure |
| US8657776B2 (en) | 2011-06-14 | 2014-02-25 | Ivantis, Inc. | Ocular implants for delivery into the eye |
| EP3659495B1 (en) | 2011-09-13 | 2022-12-14 | Dose Medical Corporation | Intraocular physiological sensor |
| US9072588B2 (en) | 2011-10-03 | 2015-07-07 | Alcon Research, Ltd. | Selectable varied control valve systems for IOP control systems |
| US8585631B2 (en) | 2011-10-18 | 2013-11-19 | Alcon Research, Ltd. | Active bimodal valve system for real-time IOP control |
| US8753305B2 (en) | 2011-12-06 | 2014-06-17 | Alcon Research, Ltd. | Bubble-driven IOP control system |
| US8771220B2 (en) | 2011-12-07 | 2014-07-08 | Alcon Research, Ltd. | Glaucoma active pressure regulation shunt |
| US8852136B2 (en) | 2011-12-08 | 2014-10-07 | Aquesys, Inc. | Methods for placing a shunt into the intra-scleral space |
| US8579848B2 (en) | 2011-12-09 | 2013-11-12 | Alcon Research, Ltd. | Active drainage systems with pressure-driven valves and electronically-driven pump |
| US8840578B2 (en) | 2011-12-09 | 2014-09-23 | Alcon Research, Ltd. | Multilayer membrane actuators |
| US20130150777A1 (en) | 2011-12-12 | 2013-06-13 | Sebastian Böhm | Glaucoma Drainage Devices Including Vario-Stable Valves and Associated Systems and Methods |
| US8585664B2 (en) | 2011-12-12 | 2013-11-19 | Alcon Research, Ltd | System and method for powering ocular implants |
| US8603024B2 (en) | 2011-12-12 | 2013-12-10 | Alcon Research, Ltd. | Glaucoma drainage devices including vario-stable valves and associated systems and methods |
| US9125721B2 (en) | 2011-12-13 | 2015-09-08 | Alcon Research, Ltd. | Active drainage systems with dual-input pressure-driven valves |
| US9339187B2 (en) | 2011-12-15 | 2016-05-17 | Alcon Research, Ltd. | External pressure measurement system and method for an intraocular implant |
| US8663150B2 (en) | 2011-12-19 | 2014-03-04 | Ivantis, Inc. | Delivering ocular implants into the eye |
| US9101444B2 (en) | 2012-01-12 | 2015-08-11 | Innfocus, Inc. | Method, surgical kit and device for treating glaucoma |
| JP6008992B2 (ja) | 2012-02-13 | 2016-10-19 | イリデックス・コーポレーション | 管状クリップを用いた眼の眼圧の低減 |
| US8986240B2 (en) | 2012-02-14 | 2015-03-24 | Alcon Research, Ltd. | Corrugated membrane actuators |
| US9173775B2 (en) | 2012-03-26 | 2015-11-03 | Glaukos Corporation | System for delivering multiple ocular implants |
| US8998838B2 (en) | 2012-03-29 | 2015-04-07 | Alcon Research, Ltd. | Adjustable valve for IOP control with reed valve |
| EP2854708B1 (en) | 2012-06-04 | 2016-10-19 | Alcon Pharmaceuticals Ltd. | Intraocular lens inserter and method for discharging an intraocular lens from a cartridge |
| US9308082B2 (en) | 2012-08-07 | 2016-04-12 | RegenEye, L.L.C. | Ocular collar stent for treating narrowing of the irideocorneal angle |
| US8864701B2 (en) | 2012-08-13 | 2014-10-21 | Alcon Research, Ltd. | Implantable MEMS device and method |
| US8956320B2 (en) | 2012-08-28 | 2015-02-17 | Alcon Research, Ltd. | Capillary valve |
| US9132034B2 (en) | 2012-10-01 | 2015-09-15 | Alcon Research, Ltd. | Valve position sensor |
| US9763829B2 (en) | 2012-11-14 | 2017-09-19 | Novartis Ag | Flow promoting ocular implant |
| US9592151B2 (en) | 2013-03-15 | 2017-03-14 | Glaukos Corporation | Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye |
| HK1219862A1 (zh) | 2013-03-15 | 2017-04-21 | Orasis Medical, Inc. | 水流动的增强 |
| US10517759B2 (en) | 2013-03-15 | 2019-12-31 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| US9226851B2 (en) | 2013-08-24 | 2016-01-05 | Novartis Ag | MEMS check valve chip and methods |
| US9289324B2 (en) | 2013-08-26 | 2016-03-22 | Novartis Ag | Externally adjustable passive drainage device |
| US9283115B2 (en) | 2013-08-26 | 2016-03-15 | Novartis Ag | Passive to active staged drainage device |
| CN103558851A (zh) | 2013-10-10 | 2014-02-05 | 杨松 | 精确感知室内活动的方法及装置 |
-
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015171553A (ja) * | 2009-05-18 | 2015-10-01 | ドーズ メディカル コーポレーションＤｏｓｅ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ | 薬剤溶出眼内インプラント |
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| EP1651291B1 (en) | 2013-03-13 |
| JP2014193366A (ja) | 2014-10-09 |
| EP2351589B1 (en) | 2013-11-06 |
| US20200155349A1 (en) | 2020-05-21 |
| JP2013009982A (ja) | 2013-01-17 |
| EP1651291A4 (en) | 2007-08-15 |
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| JP5698198B2 (ja) | 2015-04-08 |
| JP5886354B2 (ja) | 2016-03-16 |
| US10485701B2 (en) | 2019-11-26 |
| EP1651291A1 (en) | 2006-05-03 |
| US7879001B2 (en) | 2011-02-01 |
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| US20040254520A1 (en) | 2004-12-16 |
| US20070276315A1 (en) | 2007-11-29 |
| US9597230B2 (en) | 2017-03-21 |
| US7867186B2 (en) | 2011-01-11 |
| CA2530234A1 (en) | 2005-02-24 |
| US20130253404A1 (en) | 2013-09-26 |
| ES2413388T3 (es) | 2013-07-16 |
| US20040102729A1 (en) | 2004-05-27 |
| AU2004264913A1 (en) | 2005-02-24 |
| AU2004264913B2 (en) | 2011-08-25 |
| ES2445717T3 (es) | 2014-03-04 |
| US20070276316A1 (en) | 2007-11-29 |
| US20130253405A1 (en) | 2013-09-26 |
| US20180036172A1 (en) | 2018-02-08 |
| CA2530234C (en) | 2014-11-25 |
| WO2005016418A1 (en) | 2005-02-24 |
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