JP5635605B2 - 眼内インプラント及び眼内インプラントを眼球内に送出するための方法 - Google Patents
眼内インプラント及び眼内インプラントを眼球内に送出するための方法 Download PDFInfo
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- JP5635605B2 JP5635605B2 JP2012519782A JP2012519782A JP5635605B2 JP 5635605 B2 JP5635605 B2 JP 5635605B2 JP 2012519782 A JP2012519782 A JP 2012519782A JP 2012519782 A JP2012519782 A JP 2012519782A JP 5635605 B2 JP5635605 B2 JP 5635605B2
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- intraocular implant
- implant
- scleral sinus
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- intraocular
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
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- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Description
長軸60及び短軸62の長さは、患者によって異なる。短軸62の長さは、多くの患者で、1μm乃至30μmである。長軸60の長さは、多くの患者で、250μm乃至350μmである。
図6は、この詳細な説明による眼内インプラントを示す斜視図である。図6の眼内インプラント126は、全体に湾曲した長さ方向中央軸線148に沿って延びる本体128を含む。図6の実施例では、本体128の曲率半径Rを、横方向中央軸線176と本体128との間を延びる矢印で示す。
図7Aの実施例では、眼内インプラント126の遠位部分は、強膜静脈洞SCに入った状態で示してある。眼内インプラント126の近位部分は、強膜静脈洞SCの外に線維柱体網TMを通って前眼房AC内に延びる状態で示してある。図7の眼内インプラント126は、第1主表面130及び第2主表面132を持つ本体を含む。図6を参照すると、眼内インプラント126の本体は、長さ方向中央軸線を中心として湾曲しており、第1主表面130は凹状表面を有し、第2主表面132は凸状表面を有するということは理解されよう。
図13にはプッシュチューブ180が示してある。図13では、プッシュチューブ180の遠位端がインプラント126の近位端と接触した状態で示してある。図13の実施例では、プッシュチューブ180は、シース120が形成する内腔122に配置されている。シース120は、近位部分150が通路124を形成し、遠位部分152が遠位穴154を形成する。インプラント126は、シース120が形成する内腔122内に配置されている。図13では、コア166は、インプラント126が形成するチャンネル138及びシース120の遠位部分152が形成する遠位穴154を通って延びる状態で示してある。
従って、平面図、側面図、及び底面図という用語は、添付の特許請求の範囲に記載された本明細書の範囲を限定するものと解釈されてはならない。
23 隅角レンズ
25 顕微鏡
30 虹彩
32 瞳孔
34 強膜
36 角膜
38 角膜縁
40 水晶体
42 毛様体小帯
100 送出システム
102 カニューレ
104 遠位開口部
124 通路
126 眼内インプラント
AC 前眼房
H ハンドル
P 患者
PC 後眼房
RH 右手
SC 強膜静脈洞
Claims (15)
- 瞳孔を形成する虹彩を持つ眼球の強膜静脈洞の一部に少なくとも一部が置かれるようになった眼内インプラントにおいて、
第1主表面、第2主表面、第1横方向範囲、及び第2横方向範囲を持つ本体を含み、前記第1横方向範囲の前記第2横方向範囲に対するアスペクト比は、2以上であり、
前記本体は、前記第1主表面が凹状表面を含み、前記第2主表面が凸状表面を含むように長さ方向中央軸線を中心として湾曲しており、
前記本体の遠位部分が、チャンネル開口部を持つ長さ方向チャンネルを形成し、前記チャンネル開口部は、前記凹状表面の中央部分と直径方向反対側に配置されており、
前記第1横方向範囲の前記第2横方向範囲に対する前記アスペクト比は、前記眼内インプラントを強膜静脈洞に配置したとき、前記チャンネル開口部が強膜静脈洞の主側部と隣接する配向を前記眼内インプラントがとるように適合且つ構成されている、眼内インプラント。 - 請求項1に記載の眼内インプラントにおいて、
前記チャンネルは、前記チャンネル開口部が強膜静脈洞の外主側部と隣接したとき、瞳孔から遠ざかる方向に開放しており、前記外主側部は、前記強膜静脈洞の内主側部よりも前記瞳孔から遠い、眼内インプラント。 - 請求項1に記載の眼内インプラントにおいて、
前記チャンネルは所定の幅及び深さを有し、
前記幅の前記深さに対するアスペクト比は、前記眼内インプラントが強膜静脈洞に配置されたとき、前記チャンネル開口部が強膜静脈洞の主側部と隣接する配向を前記眼内インプラントがとるようなアスペクト比である、眼内インプラント。 - 請求項3に記載の眼内インプラントにおいて、
前記幅の前記深さに対するアスペクト比は、1よりも大きい、眼内インプラント。 - 請求項4に記載の眼内インプラントにおいて、
前記幅の前記深さに対するアスペクト比は、約2である、眼内インプラント。 - 請求項1に記載の眼内インプラントにおいて、
前記本体は、前記長さ方向中央軸線を中心として湾曲しているため、前記本体の前記遠位部分は、180°よりも小さい角度に亘って延びている、眼内インプラント。 - 請求項1に記載の眼内インプラントにおいて、
前記本体には、前記チャンネルと流体連通した追加の開口部が形成されており、前記インプラントの前記本体は、前記本体に形成された開口部により、50%よりも大きく開放している、眼内インプラント。 - 請求項1に記載の眼内インプラントにおいて、更に、
前記本体に付着した治療剤を含む、眼内インプラント。 - 請求項8に記載の眼内インプラントにおいて、
前記治療剤は、抗緑内障薬を含む、眼内インプラント。 - 請求項9に記載の眼内インプラントにおいて、
前記抗緑内障薬は、プロスタグランジン類似体を含む、眼内インプラント。 - 請求項10に記載の眼内インプラントにおいて、
前記プロスタグランジン類似体は、ラタノプロストを含む、眼内インプラント。 - 請求項1に記載の眼内インプラントにおいて、
前記本体は横方向中央軸線を中心として湾曲しており、前記本体の長さ方向軸線が平面を形成する、眼内インプラント。 - 請求項12に記載の眼内インプラントにおいて、
前記本体は、前記横方向中央軸線と前記本体の外範囲との間を延びる横方向曲率半径を有する、眼内インプラント。 - 請求項13に記載の眼内インプラントにおいて、
前記横方向曲率半径は実質的に一定である、眼内インプラント。 - 請求項13に記載の眼内インプラントにおいて、
前記横方向曲率半径は前記本体の長さに沿って変化する、眼内インプラント。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US22415809P | 2009-07-09 | 2009-07-09 | |
US61/224,158 | 2009-07-09 | ||
PCT/US2010/041589 WO2011006113A1 (en) | 2009-07-09 | 2010-07-09 | Ocular implants and methods for delivering ocular implants into the eye |
Publications (3)
Publication Number | Publication Date |
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JP2012532700A JP2012532700A (ja) | 2012-12-20 |
JP2012532700A5 JP2012532700A5 (ja) | 2013-08-15 |
JP5635605B2 true JP5635605B2 (ja) | 2014-12-03 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2012519782A Active JP5635605B2 (ja) | 2009-07-09 | 2010-07-09 | 眼内インプラント及び眼内インプラントを眼球内に送出するための方法 |
Country Status (7)
Country | Link |
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US (5) | US8425449B2 (ja) |
EP (1) | EP2451503B1 (ja) |
JP (1) | JP5635605B2 (ja) |
CN (1) | CN102481404B (ja) |
AU (2) | AU2010271218B2 (ja) |
CA (1) | CA2766192C (ja) |
WO (1) | WO2011006113A1 (ja) |
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AU2017202552B2 (en) | 2019-07-04 |
EP2451503A1 (en) | 2012-05-16 |
CN102481404B (zh) | 2014-03-05 |
US20160051406A1 (en) | 2016-02-25 |
US20130231603A1 (en) | 2013-09-05 |
AU2010271218B2 (en) | 2017-02-02 |
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US10406025B2 (en) | 2019-09-10 |
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AU2010271218A1 (en) | 2012-01-19 |
CA2766192A1 (en) | 2011-01-13 |
US20230165711A1 (en) | 2023-06-01 |
US20110009958A1 (en) | 2011-01-13 |
JP2012532700A (ja) | 2012-12-20 |
CN102481404A (zh) | 2012-05-30 |
AU2017202552A1 (en) | 2017-05-11 |
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