US3439675A - Deformable needle assembly - Google Patents

Deformable needle assembly Download PDF

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US3439675A
US3439675A US3439675DA US3439675A US 3439675 A US3439675 A US 3439675A US 3439675D A US3439675D A US 3439675DA US 3439675 A US3439675 A US 3439675A
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Prior art keywords
needle assembly
cannula
sheath
end
use
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Expired - Lifetime
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Martin Bruce Cohen
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Becton Dickinson and Co
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Becton Dickinson and Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M2005/341Constructions for connecting the needle, e.g. to syringe nozzle or needle hub angularly adjustable or angled away from the axis of the injector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291Shafts with additional lateral openings

Description

April22, 1969 M- B COHEN DEFORMABLE NEEDLE ASSEMBLY Filed June 14, 1966 INVENTOR.

#4 7/0 520:! cabana ATI R /S United States Patent 3,439,675 DEFORMABLE NEEDLE ASSEMBLY Martin Bruce Cohen, Maywood, N.J., assignor to Becton Dickinson and Company, Rutherford, N.J., a corporation of New Jersey Filed June 14, 1966, Ser. No. 557,533 Int. Cl. A61m /32 US. Cl. 128-239 3 Claims ABSTRACT OF THE DISCLOSURE This invention relates to an improved needle assembly usable with any one of a number of syringes and, more particularly, to an ophthalmic needle assembly of this type capable of being economically produced and efficiently shaped for the desired use by merely bending it by hand preparatory to use, while being sufliciently low in cost thereby permitting complete disposability of the entire syringe unit after a single use.

Normally, the needle assemblies available for opthalmic use are costly to manufacture because they are delicately constructed and generally fabricated with a special blunt tip and surrounding areas. A needle assembly of any other type could have adverse effects and lead to permanent damage. The special blunt tip of the typical ophthalmic needle assembly has been carefully manufactured to avoid undesirable sharp edges and yet still possess the desired characteristics for use in ophthalmic applications. Certain ophthalmic needle assemblies are preformed into special shapes and curvature to satisfy particular requirements. In the case of prior art needle assemblies, this unfortunately has resulted in increased costs to an extent that it would be unreasonable to dispose of at least the needle assembly after a single use.

It has been proposed by the prior art to construct the needle assembly of a bendable material thereby permitting it to be formed into the desired shape prior to use. However, contamination of an otherwise sterile needle assembly has frequently occurred during the bending process.

With the foregoing in mind, it has been demonstrated that there is a need for a needle assembly for ophthalmic use in which the required special tip may be economically produced, the needle assembly may be constructed of a bendable material capable of being bent by hand without danger of contamination while also being capable of use with many types of syringes, and the resulting needle assembly may be economically produced and efficiently used so as to lend itself to disposability after single use.

It is, therefore, an object of this invention to provide a disposable ophthalmic needle assembly which incorporates an inexpensive, unpointed cannula, covered by a plastic sheath and which can be economically manufactured.

Another object of this invention is to produce a needle assembly of this type with a shield whereby the assembly may be bent by hand into the desired shape immediately prior to use and before removal of the shield, thereby eliminating the danger of contamination of the needle assembly during handling and the bending process.

Still another object of this invention is to provide a needle assembly of this type usable with many types of 3,439,675 Patented Apr. 22, 1969 syringes, including a prefilled disposable ophthalmic syringe thereby providing a completely marketable and disposable unit.

With these and other objects in mind, reference is had to the attached drawings of the invention in which:

FIG. 1 is a longitudinal sectional view showing the needle assembly of the invention connected to one of a wide variety of available syringes, the combination having particular application as an ophthalmic syringe;

FIG. 2 is an enlarged fragmentary sectional side view of the needle assembly of FIG. 1 with phantom lines depicting the assembly in the process of bending to the desired shape;

FIG. 3 is a similar enlarged fragmentary sectional side view showing the shape of the cannula and sheath after it has been bent by hand and the shield has been removed;

FIG. 4 is an enlarged cross-sectional view of the needle assembly taken along the plane of line 4-4 of FIG. 2;

FIG. 5 is an enlarged sectional end view of the cannula and plastic sheath only taken along the plane of line 5-5 of FIG. 2; and

FIG. 6 is a longitudinal sectional view showing the needle assembly of the invention mounted on a conventional hub.

In FIG. 1, a needle assembly 20 of this invention is shown attached to one of the many types of syringes with which it may be used. The illustrated exemplary embodiment embraces a by-pass syringe 21 adapted to store and then release the fluid for use. The syringe 21 includes a barrel 22 which contains an elongated by-pass slot 23 cooperable with a forward stopper 24, an open rear end 25 closed by rear plunger 26 and a forward discharge end 27. The chamber 28 between stopper 24 and plunger 26 is adapted to receive the selected medicament.

The illustrated needle assembly 20 is secured to the forward end 27 of the barrel but it should be understood that any one of a number of fixed or detachable connecting structures may be employed in associating the needle assembly 20 with the typical forward reduced boss 29 con taining bore 30. With this in mind, the needle assembly 20 of the illustrated embodiment is comprised of a hollow, tubular cannula 31 having an unpointed end 32 and its entire exposed outer surface covered by a tubular plastic sheath 33. The shank end 40 of the cannula 31 fits into and is held in bore 30 of the reduced cylindrical boss 29 extending forwardly of the barrel 22. The sheath 33 abuts against the tip of the cylindrical extension 29 of the barrel 22. The sheath 33 also extends beyond the unpointed end of the cannula 31, where it forms a rounded closed blunt end 35. A pair of small diametrically opposed holes 36 in the sheath 33 and at right angles to the axis of the cannula 31 are located between the tip of the cannula 31 and the end 35 of the sheath 33. Under these circumstances, the medicament, when released from chamber 28 through by-pass slot 23, will pass through bore 30 into the lumen 41 of the cannula 31 and, finally, through the two small holes 36 in the sheath 33.

The needle assembly 20 is protected by a plastic tubular shield 37. The open rear end of the shield 37 is mounted on the outer surface of the cylindrical boss 29 of the barrel 22. The other end of the shield is closed and defines a substantially hemispherical configuration. By grasping the shield 37 before its removal, the needle assembly 20 may be bent to substantially any desired or prescribed shape typified by the curvature illustrated in FIG. 3. In this connection, any of a variety of metals or plastics may be used for cannula 31 capable of being manually bent and of retaining the induced shape. Naturally, this manual bending is most advantageously accomplished while the shield 37 is still mounted over the needle assembly 20 3 thereby avoiding the danger of contamination of the exposed parts of the needle assembly 20.

In reference to FIG. 6, it can be seen that the needle assembly 20 may be mounted on a conventional type of hub 46 and fixed in position by any common adhesive compound known to the art. The needle assembly 20 with hub 46 may be. associated with a syringe. In this manner, the needle assembly 20 with hub 46 may be independently packaged and used with a variety of difi'erent syringes, ampoules and the like.

The elements of the needle assembly 20 in FIG. 6 correspond to the elements of the needle assembly 20 depicted in FIGS. 1-5. Accordingly, they Will be similarly numbered.

Basically, this invention provides an economically manufactured low-cost needle assembly for ophthalmic use which may be used with many types of syringes, whether prefilled or not, to form a completely disposable ophthalmic syringe assembly. Economy of production allows for complete disposability after single use, whereas, in the past, ophthalmic needle assemblies simply did not lend themselves to disposability mainly because of their high cost. As will be appreciated, the needle assembly of this invention is also efiicient to use in that it may be bent by hand into any desired shape by merely grasping and bending the protective shield 37 covering the associated cannula 31 and sheath 33. In this manner, contamina tion of the needle assembly is prevented because the needle assembly 20 is not required to be touched at any time prior to use to conform it to the desired shape.

Thus, the above-mentioned objects of the invention, among others, are achieved. The range and scope of the invention are defined in the appended claims.

I claim:

1. A disposable needle assembly for ophthalmic use comprising an unpointed metal cannula, having a shank and unpointed end, a plastic sheath covering said cannula, extending from its shank to its unpointed end, said sheath extending beyond the unpointed end terminating in a rounded sealed surface, and at least one hole in the sheath intermediate the unpointed end of the cannula and the rounded sealed end of the sheath thereby providing a needle assembly of low cost construction which is economical to produce, both said cannula and sheath being bendable so as to be bent to a selected configuration, bending means surrounding the needle assembly and adapted to be manually grasped to facilitate bending of the needle assembly to a selected configuration without contaminating the needle assembly, and said cannula and sheath being constructed of such material as to maintain said selected shape after said bending means is released.

2. A needle assembly in accordance with claim 1 wherein the bending means includes a bendable, hollow, cylindrical shield covering the needle assembly, said shield having a rounded sealed end adjacent the rounded sealed end of the needle assembly, the opposite open end of the shield adapted to fit and seal itself to the barrel of the syringe.

3. A needle assembly in accordance with claim 1 wherein said needle assembly is attached to a prefilled by-pass syringe.

References Cited UNITED STATES PATENTS 1,125,887 1/1915 Schimmel 128-221 1,155,848 10/1915 Tyrrell 128-239 XR 2,705,008 3/1955 Melton.

3,094,122 6/ 1963 Gauthier et al 128-221 3,225,763 12/ 1965 Waterman 128-261 XR 3,330,282 7/1967 Visser et al 128-218 XR RICHARD A. GAUDET, Primary Examiner.

M. F. MAJESTIC, Assistant Examiner.

US. Cl. X.R.

US3439675D 1966-06-14 1966-06-14 Deformable needle assembly Expired - Lifetime US3439675A (en)

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Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4573979A (en) * 1984-08-23 1986-03-04 Innovative Surgical Products, Inc. Irrigation/aspiration tip
FR2597743A1 (en) * 1986-04-23 1987-10-30 Nissho Kk Cannula for application of a surgical adhesive
US4753636A (en) * 1983-08-02 1988-06-28 Endocon, Inc. Subcutaneous implant kit
US4990140A (en) * 1989-11-13 1991-02-05 Johnson & Johnson Medical, Inc. Flexible spray tip for syringe
US4993941A (en) * 1987-05-07 1991-02-19 Nissho Corporation Dental irrigating needle
US5053020A (en) * 1990-04-06 1991-10-01 The Upjohn Company Applicator having two cannulas
US5067944A (en) * 1988-07-05 1991-11-26 Jerry Robles Hypodermic needle guard
US5092854A (en) * 1989-11-13 1992-03-03 Johnson & Johnson Medical, Inc. Two-part flexible swivel spray tip for syringe
US6135984A (en) * 1999-01-06 2000-10-24 Dishler; Jon G. Cannula for use in corrective laser eye surgery
US6413245B1 (en) 1999-10-21 2002-07-02 Alcon Universal Ltd. Sub-tenon drug delivery
US20040147880A1 (en) * 2003-01-24 2004-07-29 Niall Duffy Device for protecting a distal portion of a catheter system during shipment and storage
US20050271704A1 (en) * 2002-04-08 2005-12-08 Hosheng Tu Injectable glaucoma implants with multiple openings
US7153316B1 (en) 2001-11-09 2006-12-26 Mcdonald Marguerite B Surgical instruments and method for corneal reformation
US20070244442A1 (en) * 2004-12-22 2007-10-18 Chowhan Masood A Device for Ophthalmic Drug Delivery
US7285107B1 (en) * 2002-10-17 2007-10-23 Alcon, Inc. Vitreoretinal instrument
US20090093789A1 (en) * 2007-10-09 2009-04-09 Alcon Research, Ltd. Method of Delivering A Rate And Temperature - Dependent Substance Into The Eye
US20090093788A1 (en) * 2007-10-09 2009-04-09 Alcon Research, Ltd. Thermal Coefficient Driven Drug Pellet Size For Ophthalmic Injection
US20090137983A1 (en) * 2000-04-14 2009-05-28 Glaukos Corporation Implant delivery device and methods thereof for treatment of ocular disorders
US20100286654A1 (en) * 2009-05-06 2010-11-11 Cesario Pereira Dos Santos Multiple Thermal Sensors in a Multiple Processor Environment for Temperature Control in a Drug Delivery Device
US20110028883A1 (en) * 2006-01-17 2011-02-03 Juan Jr Eugene De Glaucoma treatment device
US20110028884A1 (en) * 2003-11-14 2011-02-03 Minas Theodore Coroneo Ocular pressure regulation
US20110092878A1 (en) * 2001-04-07 2011-04-21 Glaukos Corporation Ocular implant delivery system and methods thereof
US20110152767A1 (en) * 2009-12-22 2011-06-23 Pinedjian Raffi S Method and Apparatus for Drug Delivery
USD641078S1 (en) 2008-12-29 2011-07-05 Ucb Pharma, S.A. Medical syringe with needle tip cap
US20110245787A1 (en) * 2010-03-30 2011-10-06 Zica Michael A Viscous fluid extraction
US20120035559A1 (en) * 2010-08-09 2012-02-09 Rucinski Paul J Device and Method for Abscess Irrigation
US8579866B2 (en) 2008-01-11 2013-11-12 Ucb Pharma, S.A. Systems and methods for administering medication
US8945038B2 (en) 2003-05-05 2015-02-03 Transcend Medical, Inc. Internal shunt and method for treating glaucoma
US9155656B2 (en) 2012-04-24 2015-10-13 Transcend Medical, Inc. Delivery system for ocular implant
US9333305B2 (en) 2008-07-18 2016-05-10 Ucb Biopharma Sprl Systems for automatically administering medication
US9480598B2 (en) 2012-09-17 2016-11-01 Novartis Ag Expanding ocular implant devices and methods
US9554940B2 (en) 2012-03-26 2017-01-31 Glaukos Corporation System and method for delivering multiple ocular implants
US9561131B2 (en) 2001-08-28 2017-02-07 Glaukos Corporation Implant delivery system and methods thereof for treating ocular disorders
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
US9597230B2 (en) 2002-04-08 2017-03-21 Glaukos Corporation Devices and methods for glaucoma treatment
US9763829B2 (en) 2012-11-14 2017-09-19 Novartis Ag Flow promoting ocular implant
US9763828B2 (en) 2009-01-28 2017-09-19 Novartis Ag Ocular implant with stiffness qualities, methods of implantation and system
US9962290B2 (en) 2006-11-10 2018-05-08 Glaukos Corporation Uveoscleral shunt and methods for implanting same
US9987163B2 (en) 2013-04-16 2018-06-05 Novartis Ag Device for dispensing intraocular substances
US10085633B2 (en) 2012-04-19 2018-10-02 Novartis Ag Direct visualization system for glaucoma treatment
USD846738S1 (en) 2017-10-27 2019-04-23 Glaukos Corporation Implant delivery apparatus

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US1125887A (en) * 1914-04-08 1915-01-19 Gustav R Schimmel Hypodermic syringe.
US1155848A (en) * 1914-09-17 1915-10-05 Charles A Tyrrell Rectal syringe.
US2705008A (en) * 1947-09-30 1955-03-29 Morton Newburger Medication cartridge-needle-needle guard unit for hypodermic syringe
US3094122A (en) * 1961-01-18 1963-06-18 Theophile E Gauthier Flexible cannula and intravenous needle combined
US3225763A (en) * 1962-06-18 1965-12-28 Chesebrough Ponds Medicinal injector
US3330282A (en) * 1964-08-21 1967-07-11 Upjohn Co Combination syringe and vial mixing container

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1125887A (en) * 1914-04-08 1915-01-19 Gustav R Schimmel Hypodermic syringe.
US1155848A (en) * 1914-09-17 1915-10-05 Charles A Tyrrell Rectal syringe.
US2705008A (en) * 1947-09-30 1955-03-29 Morton Newburger Medication cartridge-needle-needle guard unit for hypodermic syringe
US3094122A (en) * 1961-01-18 1963-06-18 Theophile E Gauthier Flexible cannula and intravenous needle combined
US3225763A (en) * 1962-06-18 1965-12-28 Chesebrough Ponds Medicinal injector
US3330282A (en) * 1964-08-21 1967-07-11 Upjohn Co Combination syringe and vial mixing container

Cited By (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753636A (en) * 1983-08-02 1988-06-28 Endocon, Inc. Subcutaneous implant kit
US4573979A (en) * 1984-08-23 1986-03-04 Innovative Surgical Products, Inc. Irrigation/aspiration tip
FR2597743A1 (en) * 1986-04-23 1987-10-30 Nissho Kk Cannula for application of a surgical adhesive
US4813928A (en) * 1986-04-23 1989-03-21 Hoechst Japan Limited Nozzle for tissue adhesive
US4993941A (en) * 1987-05-07 1991-02-19 Nissho Corporation Dental irrigating needle
US5067944A (en) * 1988-07-05 1991-11-26 Jerry Robles Hypodermic needle guard
AU629705B2 (en) * 1989-11-13 1992-10-08 Johnson & Johnson Medical, Inc. Flexible spray tip for syringe
EP0428378A2 (en) * 1989-11-13 1991-05-22 JOHNSON & JOHNSON MEDICAL, INC. Flexible spray tip for syringe
EP0428378A3 (en) * 1989-11-13 1992-06-03 Johnson & Johnson Medical, Inc. Flexible spray tip for syringe
US5092854A (en) * 1989-11-13 1992-03-03 Johnson & Johnson Medical, Inc. Two-part flexible swivel spray tip for syringe
US4990140A (en) * 1989-11-13 1991-02-05 Johnson & Johnson Medical, Inc. Flexible spray tip for syringe
US5053020A (en) * 1990-04-06 1991-10-01 The Upjohn Company Applicator having two cannulas
US6135984A (en) * 1999-01-06 2000-10-24 Dishler; Jon G. Cannula for use in corrective laser eye surgery
US6413245B1 (en) 1999-10-21 2002-07-02 Alcon Universal Ltd. Sub-tenon drug delivery
US20090138081A1 (en) * 2000-04-14 2009-05-28 Glaukos Copporation Ocular implant with anchor and methods thereof
US10485702B2 (en) 2000-04-14 2019-11-26 Glaukos Corporation System and method for treating an ocular disorder
US20090137983A1 (en) * 2000-04-14 2009-05-28 Glaukos Corporation Implant delivery device and methods thereof for treatment of ocular disorders
US8814820B2 (en) 2000-04-14 2014-08-26 Glaukos Corporation Ocular implant with therapeutic agent and methods thereof
US8808219B2 (en) 2000-04-14 2014-08-19 Glaukos Corporation Implant delivery device and methods thereof for treatment of ocular disorders
US8801648B2 (en) 2000-04-14 2014-08-12 Glaukos Corporation Ocular implant with anchor and methods thereof
US9993368B2 (en) 2000-04-14 2018-06-12 Glaukos Corporation System and method for treating an ocular disorder
US20110105987A1 (en) * 2000-04-14 2011-05-05 Glaukos Corporation System and method for treating an ocular disorder
US9572963B2 (en) 2001-04-07 2017-02-21 Glaukos Corporation Ocular disorder treatment methods and systems
US20110092878A1 (en) * 2001-04-07 2011-04-21 Glaukos Corporation Ocular implant delivery system and methods thereof
US9987472B2 (en) 2001-04-07 2018-06-05 Glaukos Corporation Ocular implant delivery systems
US10285856B2 (en) 2001-08-28 2019-05-14 Glaukos Corporation Implant delivery system and methods thereof for treating ocular disorders
US9561131B2 (en) 2001-08-28 2017-02-07 Glaukos Corporation Implant delivery system and methods thereof for treating ocular disorders
US7153316B1 (en) 2001-11-09 2006-12-26 Mcdonald Marguerite B Surgical instruments and method for corneal reformation
US9301875B2 (en) 2002-04-08 2016-04-05 Glaukos Corporation Ocular disorder treatment implants with multiple opening
US20050271704A1 (en) * 2002-04-08 2005-12-08 Hosheng Tu Injectable glaucoma implants with multiple openings
US9597230B2 (en) 2002-04-08 2017-03-21 Glaukos Corporation Devices and methods for glaucoma treatment
US10485701B2 (en) 2002-04-08 2019-11-26 Glaukos Corporation Devices and methods for glaucoma treatment
US7285107B1 (en) * 2002-10-17 2007-10-23 Alcon, Inc. Vitreoretinal instrument
US7108682B2 (en) * 2003-01-24 2006-09-19 Medtronic Vascular, Inc. Device for protecting a distal portion of a catheter system during shipment and storage
US20040147880A1 (en) * 2003-01-24 2004-07-29 Niall Duffy Device for protecting a distal portion of a catheter system during shipment and storage
US9844462B2 (en) 2003-05-05 2017-12-19 Novartis Ag Internal shunt and method for treating glaucoma
US8945038B2 (en) 2003-05-05 2015-02-03 Transcend Medical, Inc. Internal shunt and method for treating glaucoma
US8808220B2 (en) 2003-11-14 2014-08-19 Transcend Medical, Inc. Ocular pressure regulation
US10226380B2 (en) 2003-11-14 2019-03-12 Novartis Ag Ocular pressure regulation
US9351873B2 (en) 2003-11-14 2016-05-31 Transcend Medical, Inc. Ocular pressure regulation
US20110028884A1 (en) * 2003-11-14 2011-02-03 Minas Theodore Coroneo Ocular pressure regulation
US20070244442A1 (en) * 2004-12-22 2007-10-18 Chowhan Masood A Device for Ophthalmic Drug Delivery
US9789000B2 (en) 2006-01-17 2017-10-17 Novartis Ag Glaucoma treatment device
US8801649B2 (en) 2006-01-17 2014-08-12 Transcend Medical, Inc. Glaucoma treatment device
US9398977B2 (en) 2006-01-17 2016-07-26 Transcend Medical, Inc. Glaucoma treatment device
US9421130B2 (en) 2006-01-17 2016-08-23 Novartis Ag. Glaucoma treatment device
US20110028883A1 (en) * 2006-01-17 2011-02-03 Juan Jr Eugene De Glaucoma treatment device
US20110098629A1 (en) * 2006-01-17 2011-04-28 Juan Jr Eugene De Glaucoma treatment device
US8814819B2 (en) 2006-01-17 2014-08-26 Transcend Medical, Inc. Glaucoma treatment device
US9962290B2 (en) 2006-11-10 2018-05-08 Glaukos Corporation Uveoscleral shunt and methods for implanting same
US20090093789A1 (en) * 2007-10-09 2009-04-09 Alcon Research, Ltd. Method of Delivering A Rate And Temperature - Dependent Substance Into The Eye
US20090093788A1 (en) * 2007-10-09 2009-04-09 Alcon Research, Ltd. Thermal Coefficient Driven Drug Pellet Size For Ophthalmic Injection
US9901686B2 (en) 2008-01-11 2018-02-27 Ucb Biopharma Sprl Systems and methods for administering medication
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