JP3768232B2 - ２，６‐ジアミノプリン誘導体 - Google Patents

２，６‐ジアミノプリン誘導体 Download PDF

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Publication number
JP3768232B2
JP3768232B2 JP51665294A JP51665294A JP3768232B2 JP 3768232 B2 JP3768232 B2 JP 3768232B2 JP 51665294 A JP51665294 A JP 51665294A JP 51665294 A JP51665294 A JP 51665294A JP 3768232 B2 JP3768232 B2 JP 3768232B2
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JP
Japan
Prior art keywords
amino
ethyl
diphenylethyl
deoxy
ribofuranuronamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP51665294A
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English (en)
Japanese (ja)
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JPH08505864A (ja
Inventor
グレグソン，マイケル
エドワード エアズ，バリー
ブランチ イワン，ジョージ
エリス，フランク
ナイト，ジョン
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Glaxo Group Ltd
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Glaxo Group Ltd
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Publication of JPH08505864A publication Critical patent/JPH08505864A/ja
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Publication of JP3768232B2 publication Critical patent/JP3768232B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
JP51665294A 1993-01-20 1994-01-18 ２，６‐ジアミノプリン誘導体 Expired - Fee Related JP3768232B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939301000A GB9301000D0 (en) 1993-01-20 1993-01-20 Chemical compounds
GB9301000.7 1993-01-20
PCT/EP1994/000145 WO1994017090A1 (en) 1993-01-20 1994-01-18 2,6-diaminopurine derivatives

Publications (2)

Publication Number Publication Date
JPH08505864A JPH08505864A (ja) 1996-06-25
JP3768232B2 true JP3768232B2 (ja) 2006-04-19

Family

ID=10728948

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51665294A Expired - Fee Related JP3768232B2 (ja) 1993-01-20 1994-01-18 ２，６‐ジアミノプリン誘導体

Country Status (29)

Country Link
US (2) US5925624A (show.php)
EP (1) EP0680488B1 (show.php)
JP (1) JP3768232B2 (show.php)
KR (1) KR960700261A (show.php)
CN (1) CN1043997C (show.php)
AP (1) AP457A (show.php)
AT (1) ATE164849T1 (show.php)
AU (1) AU679714B2 (show.php)
CA (1) CA2153688A1 (show.php)
CZ (1) CZ187995A3 (show.php)
DE (1) DE69409503T2 (show.php)
DK (1) DK0680488T3 (show.php)
EC (1) ECSP941104A (show.php)
ES (1) ES2117249T3 (show.php)
FI (1) FI953489A7 (show.php)
GB (1) GB9301000D0 (show.php)
HU (1) HU211914A9 (show.php)
IL (1) IL108372A (show.php)
IS (1) IS4121A (show.php)
NO (1) NO305603B1 (show.php)
NZ (1) NZ259880A (show.php)
PE (1) PE54194A1 (show.php)
PL (1) PL309975A1 (show.php)
RU (1) RU2129561C1 (show.php)
SI (1) SI9400021A (show.php)
SK (1) SK281229B6 (show.php)
TW (1) TW267168B (show.php)
WO (1) WO1994017090A1 (show.php)
ZA (1) ZA94335B (show.php)

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IL108372A0 (en) 1994-04-12
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GB9301000D0 (en) 1993-03-10
CN1043997C (zh) 1999-07-07
NO952872L (no) 1995-09-13
AP9400613A0 (en) 1994-01-31
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AP457A (en) 1996-02-01
ATE164849T1 (de) 1998-04-15
ZA94335B (en) 1994-10-24
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DK0680488T3 (da) 1999-01-25
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CZ187995A3 (en) 1996-01-17
EP0680488A1 (en) 1995-11-08
WO1994017090A1 (en) 1994-08-04
IL108372A (en) 1998-06-15
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US5925624A (en) 1999-07-20
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US5889178A (en) 1999-03-30
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