|
GB984365A
(en)
|
1961-10-03 |
1965-02-24 |
Ici Ltd |
Pyrimidine derivatives
|
|
US3470179A
(en)
|
1966-06-14 |
1969-09-30 |
Sandoz Ag |
4-substituted-3,4-dihydroquinazolines
|
|
US3549624A
(en)
|
1967-08-17 |
1970-12-22 |
Pfizer & Co C |
2-substituted-2-delta**2-tetrahydropyrimidines and delta**2-im
|
|
US3438995A
(en)
|
1968-01-08 |
1969-04-15 |
Melville Sahyun |
Diazaheterocyclic substituted benz-oxaheterocyclic compounds
|
|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3551427A
(en)
|
1969-05-09 |
1970-12-29 |
Sandoz Ag |
4-thienyl-2-(1h)-quinazolones
|
|
US4223151A
(en)
*
|
1972-05-16 |
1980-09-16 |
American Home Products Corporation |
Process for preparing polycyclic heterocycles having a pyran ring
|
|
US4036842A
(en)
|
1972-05-16 |
1977-07-19 |
American Home Products Corporation |
Process for preparing polycyclic heterocycles having a pyran ring
|
|
US4021451A
(en)
*
|
1972-05-16 |
1977-05-03 |
American Home Products Corporation |
Process for preparing polycyclic heterocycles having a pyran ring
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
JPS51125287A
(en)
*
|
1974-12-04 |
1976-11-01 |
Takeda Chem Ind Ltd |
Aprocess for preparing heterocyclic compounds
|
|
US4021452A
(en)
|
1975-04-23 |
1977-05-03 |
American Cyanamid Company |
2,5-Dihydro-2,5-dialkoxyfuran derivatives
|
|
JPS541910Y2
(enExample)
|
1975-12-12 |
1979-01-26 |
|
|
|
JPS5919549B2
(ja)
*
|
1976-01-01 |
1984-05-07 |
武田薬品工業株式会社 |
異節環状化合物
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
GB1552004A
(en)
|
1976-05-26 |
1979-09-05 |
Takeda Chemical Industries Ltd |
Isochroman derivatives
|
|
US4127665A
(en)
|
1978-01-18 |
1978-11-28 |
Pfizer Inc. |
Thienohydantoin derivatives
|
|
US4556656A
(en)
*
|
1978-10-23 |
1985-12-03 |
The Upjohn Company |
2-Benzoxepins
|
|
FR2459239A1
(fr)
|
1979-06-20 |
1981-01-09 |
Logeais Labor Jacques |
Nouveaux derives amines du benzothiazole, leur procede de preparation et leur application en therapeutique
|
|
US4500543A
(en)
|
1982-06-01 |
1985-02-19 |
Abbott Laboratories |
Substituted 1-aminomethyl-phthalans
|
|
US4518779A
(en)
*
|
1982-09-27 |
1985-05-21 |
Pennwalt Corporation |
1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines
|
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
|
PH30676A
(en)
|
1986-07-22 |
1997-09-16 |
Boehringer Ingelhein Kg |
Hetrazepine compounds which have useful pharmaceutical utility
|
|
JPH049367Y2
(enExample)
|
1986-12-27 |
1992-03-09 |
|
|
|
JPS646267A
(en)
*
|
1987-02-04 |
1989-01-10 |
Daiichi Seiyaku Co |
2-benzopyran derivative
|
|
EP0305332A3
(de)
*
|
1987-08-26 |
1990-04-04 |
Ciba-Geigy Ag |
Imidazol-Derivate
|
|
AU616488B2
(en)
|
1988-03-16 |
1991-10-31 |
Dr. Lo Zambeletti S.P.A. |
Heterocyclic derivatives
|
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
|
DE3827727A1
(de)
|
1988-08-16 |
1990-02-22 |
Boehringer Ingelheim Kg |
Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
|
|
GB8824400D0
(en)
|
1988-10-18 |
1988-11-23 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP0368175A1
(de)
|
1988-11-06 |
1990-05-16 |
Boehringer Ingelheim Kg |
3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.
|
|
GB8827479D0
(en)
|
1988-11-24 |
1988-12-29 |
Zambeletti Spa L |
Novel compounds
|
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
|
US4994486A
(en)
|
1989-05-31 |
1991-02-19 |
Abbott Laboratories |
Dopaminergic compounds
|
|
US4963568A
(en)
*
|
1989-05-31 |
1990-10-16 |
Abbott Laboratories |
Dopamine agonists
|
|
US5621133A
(en)
|
1989-05-31 |
1997-04-15 |
Deninno; Michael P. |
Dopamine agonists
|
|
EP0416740A3
(en)
|
1989-08-08 |
1991-08-28 |
Beecham Group P.L.C. |
Novel compounds with renin-inhibiting activity
|
|
JPH0735373B2
(ja)
|
1989-08-11 |
1995-04-19 |
三共株式会社 |
カルボン酸アミド化合物
|
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
|
GB8926560D0
(en)
|
1989-11-24 |
1990-01-17 |
Zambeletti Spa L |
Pharmaceuticals
|
|
DE3940477A1
(de)
|
1989-12-07 |
1991-06-13 |
Bayer Ag |
Hetaryl-substituierte pyridinylpyrimidin-derivate
|
|
US5032598A
(en)
|
1989-12-08 |
1991-07-16 |
Merck & Co., Inc. |
Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
|
|
GB8927872D0
(en)
|
1989-12-08 |
1990-02-14 |
Beecham Group Plc |
Pharmaceuticals
|
|
US5420151A
(en)
|
1989-12-22 |
1995-05-30 |
Aktiebolaget Astra |
Chroman derivatives
|
|
JPH03223277A
(ja)
|
1989-12-29 |
1991-10-02 |
Yoshitomi Pharmaceut Ind Ltd |
ベンゾチオフェン誘導体
|
|
KR0166088B1
(ko)
|
1990-01-23 |
1999-01-15 |
. |
수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
|
|
JPH0735373Y2
(ja)
|
1990-02-22 |
1995-08-09 |
松下電器産業株式会社 |
トランス
|
|
ZA912744B
(en)
|
1990-03-23 |
1992-02-26 |
Zambeletti Spa L |
Pharmaceuticals
|
|
JPH049367A
(ja)
|
1990-04-26 |
1992-01-14 |
Zeria Pharmaceut Co Ltd |
アリールアルカノイル誘導体，該化合物の製造中間体及びそれらを含有する医薬
|
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
|
US5238939A
(en)
|
1990-05-25 |
1993-08-24 |
Akzo N.V. |
Isochromane derivatives
|
|
GB9018139D0
(en)
|
1990-08-17 |
1990-10-03 |
Pfizer Ltd |
Therapeutic agents
|
|
NZ240155A
(en)
|
1990-10-29 |
1992-10-28 |
Ishihara Sangyo Kaisha |
Heterocyclyl acyl and (hexahydro) indanyl acyl substituted hydrazine derivatives, preparation thereof and pesticidal compositions
|
|
DE4104257A1
(de)
|
1991-02-13 |
1992-08-20 |
Boehringer Ingelheim Kg |
Verwendung von anellierten tetrahydropyridinessigsaeurederivaten fuer die behandlung neurologischer erkrankungen
|
|
GB9104839D0
(en)
|
1991-03-07 |
1991-04-17 |
Zambeletti Spa L |
Novel compounds
|
|
JPH0826011B2
(ja)
*
|
1991-04-25 |
1996-03-13 |
アサヒビール株式会社 |
アミノメチルイソクロマン誘導体およびその製造方法
|
|
NZ243065A
(en)
|
1991-06-13 |
1995-07-26 |
Lundbeck & Co As H |
Piperidine derivatives and pharmaceutical compositions
|
|
US5288749A
(en)
*
|
1991-12-20 |
1994-02-22 |
Abbott Laboratories |
Tertiary and secondary amines as alpha-2 antagonists and serotonin uptake inhibitors
|
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
|
PH31294A
(en)
|
1992-02-13 |
1998-07-06 |
Thomae Gmbh Dr K |
Benzimidazolyl derivatives, pharmaceutical compositions containing these compounds and process for preparing them.
|
|
JP3223277B2
(ja)
|
1992-04-10 |
2001-10-29 |
カシオ計算機株式会社 |
楽音制御装置
|
|
FR2692264B1
(fr)
|
1992-06-12 |
1994-08-05 |
Adir |
Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
|
|
IT1255178B
(it)
|
1992-06-26 |
1995-10-20 |
Pierrel Spa |
N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica
|
|
ATE169179T1
(de)
|
1992-12-02 |
1998-08-15 |
Ciba Geigy Ag |
Selektiv-herbizides mittel
|
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
|
TW334423B
(en)
|
1993-10-22 |
1998-06-21 |
Hoffmann La Roche |
Tricyclic 1-aminoethylpyrrole-derivatives
|
|
JP3163068B2
(ja)
|
1993-12-27 |
2001-05-08 |
日本建工株式会社 |
野縁取付け金具
|
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
|
FR2723091B1
(fr)
|
1994-07-29 |
1996-11-08 |
Esteve Labor Dr |
Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles
|
|
WO1996038435A1
(en)
*
|
1995-05-30 |
1996-12-05 |
Abbott Laboratories |
Dopamine agonists
|
|
FR2734819B1
(fr)
|
1995-05-31 |
1997-07-04 |
Adir |
Nouveaux composes de la piperazine, de la piperidine et de la 1,2,5,6-tetrahydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant
|
|
SE9702563D0
(sv)
|
1997-07-02 |
1997-07-02 |
Astra Ab |
Compounds
|
|
DE19751949A1
(de)
|
1997-11-24 |
1999-05-27 |
Bayer Ag |
Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
|
|
WO1999046267A1
(en)
|
1998-03-12 |
1999-09-16 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases (ptpases)
|
|
CA2323493A1
(en)
|
1998-03-12 |
1999-09-16 |
Todd Kevin Jones |
Modulators of protein tyrosine phosphatases (ptpases)
|
|
JP2004500308A
(ja)
|
1998-03-12 |
2004-01-08 |
ノボ ノルディスク アクティーゼルスカブ |
プロテインチロシンホスアターゼのモジュレーター
|
|
US6262044B1
(en)
|
1998-03-12 |
2001-07-17 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases (PTPASES)
|
|
DE19817262A1
(de)
|
1998-04-18 |
1999-10-21 |
Bayer Ag |
Neue 2-heterocyclisch substituierte Dihydropyrimidine
|
|
DE19817265A1
(de)
|
1998-04-18 |
1999-10-21 |
Bayer Ag |
Verwendung von Dihydropyrimidinen als Arzneimittel und neue Stoffe
|
|
DE69912279T2
(de)
|
1998-06-30 |
2004-07-29 |
Eli Lilly And Co., Indianapolis |
5-ht1f agonisten
|
|
EP1123292A1
(en)
|
1998-10-21 |
2001-08-16 |
Novo Nordisk A/S |
New compounds, their preparation and use
|
|
CZ20012130A3
(cs)
|
1998-12-14 |
2001-10-17 |
Fujisawa Pharmaceutical Co., Ltd. |
Piperazinový derivát, způsob jeho výroby a pouľití
|
|
EP1147113B1
(en)
|
1999-01-19 |
2006-06-07 |
Neurosearch A/S |
Fused heterocyclic compounds and their use in the treatment of neurodegenerative diseases
|
|
US6313309B1
(en)
|
1999-04-05 |
2001-11-06 |
Ortho-Mcneil Pharmaceutical, Inc. |
4-thionaphthyl—1H—imidazoles which are usefulα22-adrenoceptoR agonists/ antagonists
|
|
WO2000068230A1
(en)
|
1999-05-05 |
2000-11-16 |
Darwin Discovery Limited |
9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7 inhibitors
|
|
GB9914025D0
(en)
|
1999-06-17 |
1999-08-18 |
Zeneca Ltd |
Chemical compounds
|
|
US7019026B1
(en)
|
1999-09-10 |
2006-03-28 |
Novo Nordisk A/S |
Modulators of Protein Tyrosine Phosphatases (PTPases)
|
|
EP1214060A2
(en)
|
1999-09-10 |
2002-06-19 |
Novo Nordisk A/S |
Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48
|
|
AU7961200A
(en)
|
1999-10-29 |
2001-05-14 |
Kaken Pharmaceutical Co., Ltd. |
Urea derivative, process for producing the same, and medicine containing the urea derivative
|
|
AR030537A1
(es)
|
1999-11-05 |
2003-08-27 |
Abbott Lab |
Acidos quinolincarboxilicos y naftiridincarboxilico antibacterianos
|
|
CN1438890A
(zh)
|
2000-02-25 |
2003-08-27 |
弗·哈夫曼-拉罗切有限公司 |
腺苷受体调制剂
|
|
JP5074653B2
(ja)
|
2000-03-29 |
2012-11-14 |
サイクラセル リミテッド |
２−置換４−ヘテロアリール−ピリミジンおよび増殖性障害におけるその使用
|
|
IL152023A0
(en)
|
2000-04-26 |
2003-04-10 |
Eisai Co Ltd |
Compounds having adenosine a2 receptor antagonism and pharmaceutical compositions containing the same
|
|
AU2001277731A1
(en)
|
2000-08-09 |
2002-02-18 |
Welfide Corporation |
Fused bicyclic amide compounds and medicinal use thereof
|
|
WO2002022614A1
(en)
|
2000-09-12 |
2002-03-21 |
Sankyo Company,Limited |
Quinolizine derivatives
|
|
US6660731B2
(en)
|
2000-09-15 |
2003-12-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
WO2002066443A2
(en)
|
2001-02-21 |
2002-08-29 |
Ono Pharmaceutical Co., Ltd. |
2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives
|
|
JP2004535381A
(ja)
|
2001-04-13 |
2004-11-25 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ｃ−ＪｕｎＮ末端キナーゼ（ＪＮＫ）および他のプロテインキナーゼのインヒビター
|
|
WO2002102387A1
(en)
|
2001-06-18 |
2002-12-27 |
H. Lundbeck A/S |
Treatment of neuropathic pain
|
|
EP1409476B1
(en)
|
2001-07-11 |
2004-12-15 |
Eli Lilly And Company |
Pharmaceutical compounds with serotonin receptor activity
|
|
US20040180883A1
(en)
|
2001-07-11 |
2004-09-16 |
Jeremy Gilmore |
Pharmaceutical compounds with serotonin receptor activity
|
|
IL161576A0
(en)
|
2001-10-26 |
2004-09-27 |
Aventis Pharma Inc |
Benzimidazoles and analogues and their use as protein kinases inhibitors
|
|
JP2003261566A
(ja)
|
2002-03-11 |
2003-09-19 |
Sankyo Co Ltd |
キノリジンを含有する医薬
|
|
MXPA04009747A
(es)
|
2002-04-10 |
2004-12-13 |
Dongbu Hannong Chemical Co Ltd |
Derivados de benzopirano sustituidos con aminas secundarias que incluyen tetrazol, metodo para la preparacion de los mismos y composiciones farmaceuticas que los contienen.
|
|
TW200930291A
(en)
|
2002-04-29 |
2009-07-16 |
Bayer Cropscience Ag |
Pesticidal heterocycles
|
|
US7276522B2
(en)
|
2002-05-21 |
2007-10-02 |
Allergan, Inc. |
4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones, 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
|
|
US7091232B2
(en)
|
2002-05-21 |
2006-08-15 |
Allergan, Inc. |
4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
|
|
US7358269B2
(en)
|
2002-05-21 |
2008-04-15 |
Allergan, Inc. |
2-((2-Thioxo-2,3-dihydro-1H-imidazol-4-yl)methyl)-3,4-dihydronapthalen-1(2H)-one
|
|
US7323485B2
(en)
|
2002-05-21 |
2008-01-29 |
Allergan, Inc. |
4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds
|
|
SE0202134D0
(sv)
|
2002-07-08 |
2002-07-08 |
Astrazeneca Ab |
Therapeutic agents
|
|
MXPA05004033A
(es)
|
2002-10-16 |
2005-06-08 |
Isis Innovation |
Hidroxilasas de asparaginil y moduladores de las mismas.
|
|
EP1587482A4
(en)
|
2003-01-31 |
2010-08-25 |
Technion Res & Dev Foundation |
INFLAMMATORY COMPOSITIONS AND ITS USES
|
|
EP2527326B1
(en)
|
2003-03-07 |
2014-10-08 |
Santen Pharmaceutical Co., Ltd |
Novel compounds having 4-pyridylalkylthio group as substituent
|
|
JP2004269449A
(ja)
|
2003-03-11 |
2004-09-30 |
Ishihara Sangyo Kaisha Ltd |
ベンズアミド誘導体、それらの製造方法及びそれらを含有する有害生物防除剤
|
|
US7205318B2
(en)
|
2003-03-18 |
2007-04-17 |
Bristol-Myers Squibb Company |
Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors
|
|
WO2004087680A1
(en)
|
2003-03-31 |
2004-10-14 |
Taisho Pharmaceutical Co., Ltd. |
Novel quinazoline derivatives and methods of treatment related to the use thereof
|
|
CA2521271C
(en)
|
2003-04-04 |
2011-01-04 |
Novartis Ag |
Quinoline-2-one-derivatives for the treatment of airways diseases
|
|
GB0308466D0
(en)
|
2003-04-11 |
2003-05-21 |
Novartis Ag |
Organic compounds
|
|
WO2004112719A2
(en)
|
2003-06-19 |
2004-12-29 |
Smithkline Beecham Corporation |
Chemical compounds
|
|
US20050032873A1
(en)
|
2003-07-30 |
2005-02-10 |
Wyeth |
3-Amino chroman and 2-amino tetralin derivatives
|
|
DE10347385A1
(de)
|
2003-10-08 |
2005-05-12 |
Schering Ag |
Umgelagerte Pentanole, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
JP2005145859A
(ja)
|
2003-11-13 |
2005-06-09 |
Nippon Steel Chem Co Ltd |
脱水素化方法及び芳香族複素環化合物の製造方法
|
|
DE10360793A1
(de)
|
2003-12-23 |
2005-07-28 |
Grünenthal GmbH |
Spirocyclische Cyclohexan-Derivate
|
|
EP1715855A4
(en)
|
2004-01-29 |
2010-06-16 |
Elixir Pharmaceuticals Inc |
ANTIVIRAL DRUGS
|
|
DE102004004974A1
(de)
|
2004-01-31 |
2005-08-18 |
Aventis Pharma Deutschland Gmbh |
Thieno-Iminosäure-Derivate als Inhibitoren von Matrix-Metalloproteinasen
|
|
GB0403155D0
(en)
|
2004-02-12 |
2004-03-17 |
Vernalis Res Ltd |
Chemical compounds
|
|
EP1734961A2
(en)
|
2004-03-09 |
2006-12-27 |
Elan Pharmaceuticals, Inc. |
Methods of treatment of amyloidosis using bi-cyclic aspartyl protease inhibitors
|
|
KR100553398B1
(ko)
|
2004-03-12 |
2006-02-16 |
한미약품 주식회사 |
티에노[3,2-ｃ]피리딘 유도체의 제조 방법 및 이에사용되는 중간체
|
|
WO2005095326A2
(en)
|
2004-03-25 |
2005-10-13 |
Elan Pharmaceuticals, Inc. |
2-amino- and 2-thio-substituted 1,3-diaminopropanes
|
|
ES2342083T3
(es)
|
2004-04-29 |
2010-07-01 |
Aventis Pharmaceuticals Inc. |
3-piperidinilisocroman-5-oles como agonistas de dopamina.
|
|
JP2008508314A
(ja)
|
2004-07-28 |
2008-03-21 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
ステロイドホルモン核内受容体のモジュレーターとしての化合物および組成物
|
|
SE0401970D0
(sv)
|
2004-08-02 |
2004-08-02 |
Astrazeneca Ab |
Novel compounds
|
|
SE0401971D0
(sv)
|
2004-08-02 |
2004-08-02 |
Astrazeneca Ab |
Piperidne derivatives
|
|
EP1634873A1
(en)
|
2004-08-27 |
2006-03-15 |
Laboratorios Del Dr. Esteve, S.A. |
Sigma receptor inhibitors
|
|
FR2875230A1
(fr)
|
2004-09-13 |
2006-03-17 |
Sanofi Aventis Sa |
Derives de pyrazole condense, leur preparation et leur application en therapeutique
|
|
JP2006117568A
(ja)
|
2004-10-20 |
2006-05-11 |
Mitsubishi Pharma Corp |
チオフェン環を有する新規アミド誘導体及びその医薬としての用途
|
|
US7214704B2
(en)
|
2004-11-15 |
2007-05-08 |
Bristol-Myers Squibb Company |
2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors
|
|
CN101115749B
(zh)
|
2004-12-17 |
2011-06-22 |
安姆根有限公司 |
氨基嘧啶化合物和使用方法
|
|
DE102004063227A1
(de)
|
2004-12-22 |
2006-07-06 |
Schering Ag |
Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
|
|
EP1856126A2
(en)
|
2005-02-17 |
2007-11-21 |
Wyeth a Corporation of the State of Delaware |
Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
|
|
US7884109B2
(en)
|
2005-04-05 |
2011-02-08 |
Wyeth Llc |
Purine and imidazopyridine derivatives for immunosuppression
|
|
PE20061297A1
(es)
|
2005-04-22 |
2006-12-24 |
Wyeth Corp |
Compuestos derivados de cromano y cromeno moduladores del receptor de serotonina 5-ht2c
|
|
CA2605594A1
(en)
|
2005-04-22 |
2006-11-02 |
Daiichi Sankyo Company, Limited |
Heterocyclic compound
|
|
WO2006117305A1
(en)
|
2005-05-04 |
2006-11-09 |
F. Hoffmann-La Roche Ag |
(3,4-dihydro-quinazolin-2-yl)-(2-aryloxy-ethyl)-amines having an activity on the 5-ht receptor
|
|
CN101228121A
(zh)
*
|
2005-05-23 |
2008-07-23 |
阿斯利康(瑞典)有限公司 |
调节5ht6受体的新的8-磺酰基-3-氨基取代的苯并二氢吡喃或四氢化萘衍生物
|
|
WO2007001939A1
(en)
|
2005-06-27 |
2007-01-04 |
Janssen Pharmaceutica N.V. |
Tetrahydro-pyranopyrazole compounds displaying cannabinoid modulating activities
|
|
WO2007002681A2
(en)
|
2005-06-27 |
2007-01-04 |
E. I. Du Pont De Nemours And Company |
Electrically conductive polymer compositions
|
|
JP2009505948A
(ja)
|
2005-07-11 |
2009-02-12 |
デブジェン エヌブイ |
キナーゼ阻害剤としてのアミド誘導体
|
|
US7598255B2
(en)
|
2005-08-04 |
2009-10-06 |
Janssen Pharmaceutica Nv |
Pyrimidine compounds as serotonin receptor modulators
|
|
TW200800201A
(en)
|
2005-11-18 |
2008-01-01 |
Lilly Co Eli |
Pyrimidinyl benzothiophene compounds
|
|
US7745484B2
(en)
|
2005-11-21 |
2010-06-29 |
Amgen Inc. |
Beta-secretase modulators and methods of use
|
|
WO2007095586A2
(en)
|
2006-02-14 |
2007-08-23 |
The Trustees Of Columbia University In The City Of New York |
Neuronal pain pathway modulators
|
|
US20080027087A1
(en)
|
2006-02-21 |
2008-01-31 |
Ampla Pharmaceuticals, Inc. |
CB1 antagonists and inverse agonists
|
|
EP1829869A1
(en)
|
2006-03-02 |
2007-09-05 |
Laboratorios Del Dr. Esteve, S.A. |
4,5,6,7-Tetrahydrobenzo[b]thiophene derivatives and their use as sigma receptor ligands
|
|
BRPI0709817A2
(pt)
|
2006-04-12 |
2011-07-26 |
Wyeth Corp |
composto da fàrmula i; mÉtodo para o tratamento de um distérbio do sistema nervoso central relacionado ou afetado pelo receptor de 5-ht6 em um paciente que necessita deste; composiÇço farmacÊutica; e processo para a preparaÇço de um composto da fàrmula i
|
|
US20090318690A1
(en)
|
2006-04-28 |
2009-12-24 |
Eisai R&D Management Co., Ltd. |
Benzisoxazole Compound
|
|
CA2658764A1
(en)
|
2006-07-20 |
2008-01-24 |
Mehmet Kahraman |
Benzothiophene inhibitors of rho kinase
|
|
WO2008042422A2
(en)
|
2006-10-04 |
2008-04-10 |
Schering Corporation |
Bicyclic and tricyclic derivatives as thrombin receptor antagonists
|
|
US7960569B2
(en)
|
2006-10-17 |
2011-06-14 |
Bristol-Myers Squibb Company |
Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
|
|
CA2670259A1
(en)
|
2006-11-15 |
2008-05-22 |
Genetic Technologies Limited |
Compounds, compositions and methods for controlling invertebrate pests
|
|
WO2009008906A2
(en)
|
2007-02-06 |
2009-01-15 |
The Trustees Of The University Of Pennsylvania |
Therapeutic compounds for blocking dna synthesis of pox viruses
|
|
JP5283846B2
(ja)
|
2007-02-09 |
2013-09-04 |
三菱レイヨン株式会社 |
成形体とその製造方法
|
|
EP2111231A4
(en)
|
2007-02-13 |
2010-12-15 |
Univ Northeastern |
METHOD AND COMPOSITIONS FOR IMPROVING IMMUNE REACTIONS
|
|
US8012986B2
(en)
|
2007-04-02 |
2011-09-06 |
Hoffmann-La Roche Inc. |
Pyridine and pyrimidine derivatives as MGLUR2 antagonists
|
|
US7598417B2
(en)
|
2007-04-12 |
2009-10-06 |
Allergan, Inc. |
Substituted fluoroethyl ureas as alpha 2 adrenergic agents
|
|
EP1982987A1
(en)
|
2007-04-16 |
2008-10-22 |
Laboratorios del Dr. Esteve S.A. |
Spiro-pyrano-pyrazole derivatives
|
|
EP1982714A1
(en)
|
2007-04-16 |
2008-10-22 |
Laboratorios del Dr. Esteve S.A. |
Pyrano-pyrazole-amines
|
|
EP2020414A1
(en)
|
2007-06-20 |
2009-02-04 |
Laboratorios del Dr. Esteve S.A. |
spiro[piperidine-4,4'-thieno[3,2-c]pyran] derivatives and related compounds as inhibitors of the sigma receptor for the treatment of psychosis
|
|
US8338623B2
(en)
|
2007-07-09 |
2012-12-25 |
Abbvie Inc. |
Compounds as cannabinoid receptor ligands
|
|
US8022209B2
(en)
|
2007-09-12 |
2011-09-20 |
Janssen Pharmaceutica Nv |
Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor
|
|
KR101103118B1
(ko)
|
2007-11-02 |
2012-01-04 |
동아제약주식회사 |
신규한 1,3-디히드로-5-이소벤조퓨란카르보니트릴 유도체 화합물 및 이를 함유하는 조루증 치료용 약학조성물
|
|
ES2469824T3
(es)
|
2007-11-21 |
2014-06-20 |
Janssen Pharmaceutica N.V. |
Espiropiperidinas para su uso como inhibidores de la triptasa
|
|
US7973051B2
(en)
|
2007-11-30 |
2011-07-05 |
Hoffman-La Roche Inc. |
Aminothiazoles as FBPase inhibitors for diabetes
|
|
US8268754B2
(en)
|
2007-12-07 |
2012-09-18 |
Nissan Chemical Industries, Ltd. |
Substituted dihydroazole compound and pest control agent
|
|
CN101468987B
(zh)
|
2007-12-26 |
2011-06-08 |
香港南北兄弟国际投资有限公司 |
2-杂环取代的二氢嘧啶消旋化合物的拆分方法
|
|
CN101468986B
(zh)
|
2007-12-26 |
2010-12-29 |
香港南北兄弟国际投资有限公司 |
一种二氢嘧啶消旋化合物的拆分方法
|
|
WO2009085256A1
(en)
|
2007-12-27 |
2009-07-09 |
Panacos Pharmaceuticals, Inc. |
Anti-hiv compounds
|
|
CN101759710B
(zh)
|
2008-10-06 |
2011-10-05 |
山东轩竹医药科技有限公司 |
含有取代的氮杂环的头孢菌素衍生物
|
|
WO2010053583A2
(en)
|
2008-11-10 |
2010-05-14 |
Dana Farber Cancer Institute |
Small molecule cd4 mimetics and uses thereof
|
|
US9139589B2
(en)
|
2009-01-30 |
2015-09-22 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
AR075442A1
(es)
|
2009-02-16 |
2011-03-30 |
Abbott Gmbh & Co Kg |
Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia
|
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
|
US8673920B2
(en)
*
|
2009-05-06 |
2014-03-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
TW201041757A
(en)
|
2009-05-20 |
2010-12-01 |
Univ Nat Taiwan Science Tech |
Method for simulating, fabricating or duplicating an oil painting
|
|
US9284307B2
(en)
|
2009-08-05 |
2016-03-15 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors
|
|
WO2011036889A1
(ja)
|
2009-09-25 |
2011-03-31 |
武田薬品工業株式会社 |
複素環化合物
|
|
MX2012005690A
(es)
|
2009-11-16 |
2012-06-13 |
Lilly Co Eli |
Compuestos de espiropiperidina como antagonista del receptor orl-1.
|
|
UA107943C2
(xx)
|
2009-11-16 |
2015-03-10 |
Lilly Co Eli |
Сполуки спіропіперидину як антагоністи рецептора orl-1
|
|
KR102074089B1
(ko)
|
2009-12-04 |
2020-02-05 |
선오비온 파마슈티컬스 인코포레이티드 |
다환형 화합물 및 이의 사용 방법
|
|
JP5794922B2
(ja)
|
2009-12-28 |
2015-10-14 |
一般社団法人ファルマバレープロジェクト支援機構 |
１，３，４−オキサジアゾール−２−カルボキサミド化合物
|
|
EP2531804B1
(en)
|
2010-02-01 |
2018-08-29 |
SGL Carbon SE |
Ceramic based armor and process for producing said armor
|
|
EP2377850A1
(en)
|
2010-03-30 |
2011-10-19 |
Pharmeste S.r.l. |
TRPV1 vanilloid receptor antagonists with a bicyclic portion
|
|
EP2560636A4
(en)
|
2010-04-23 |
2013-11-27 |
Kineta Inc |
ANTIVIRAL CONNECTIONS
|
|
US9051280B2
(en)
|
2010-08-13 |
2015-06-09 |
AbbVie Deutschland GmbH & Co. KG |
Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US8883839B2
(en)
|
2010-08-13 |
2014-11-11 |
Abbott Laboratories |
Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
EP3053925A1
(en)
|
2010-12-16 |
2016-08-10 |
F. Hoffmann-La Roche AG |
Tricyclic pi3k inhibitor compounds and methods of use
|
|
US8569339B2
(en)
|
2011-03-10 |
2013-10-29 |
Boehringer Ingelheim International Gmbh |
Soluble guanylate cyclase activators
|
|
CN102731574B
(zh)
|
2011-03-30 |
2016-03-02 |
中国人民解放军军事医学科学院毒物药物研究所 |
噻吩并吡啶类α-胺基苄基膦酸酯、其制备方法及用途
|
|
WO2013010453A1
(en)
|
2011-07-15 |
2013-01-24 |
Abbott Laboratories |
Chemoking receptor antagonists
|
|
WO2013067248A1
(en)
|
2011-11-04 |
2013-05-10 |
Vertex Pharmaceuticals Incorporated |
Benzoxazines as modulators of ion channels
|
|
JP6250561B2
(ja)
|
2012-02-08 |
2017-12-20 |
サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． |
ヘテロアリール化合物およびそれらの使用方法
|
|
MX2014014911A
(es)
|
2012-06-20 |
2015-05-15 |
Univ Vanderbilt |
Análogos de alcoxi pirazol bicíclico sustituido como moduladores alostéricos de receptores de mglur5.
|
|
RU2664541C2
(ru)
|
2012-11-13 |
2018-08-20 |
Эррэй Биофарма Инк. |
Бициклические соединения мочевины, тиомочевины, гуанидина и цианогуанидина, пригодные для лечения боли
|
|
WO2014106238A1
(en)
|
2012-12-31 |
2014-07-03 |
Fang, Qun, Kevin |
Heterocyclic compounds and methods of use thereof
|
|
JP2014214130A
(ja)
|
2013-04-26 |
2014-11-17 |
大正製薬株式会社 |
ジヒドロイミダゾオキサゾール誘導体を含有する医薬
|
|
CN111925360B
(zh)
*
|
2015-02-11 |
2024-03-22 |
赛诺维信制药公司 |
用于治疗cns障碍的1-杂环基异苯并二氢吡喃基化合物和类似物
|
|
KR102623321B1
(ko)
|
2015-02-11 |
2024-01-09 |
선오비온 파마슈티컬스 인코포레이티드 |
중추 신경계 질환을 치료하기 위한 융합된 다이하이드로-4h-피라졸로[5,1-c][1,4]옥사진일 화합물 및 유사체
|
|
EP3490607A4
(en)
|
2016-07-29 |
2020-04-08 |
Sunovion Pharmaceuticals Inc. |
COMPOUNDS AND COMPOSITIONS, AND USES THEREOF
|
|
JP7187437B2
(ja)
|
2016-07-29 |
2022-12-12 |
サノビオン ファーマシューティカルズ インク |
化合物および組成物ならびにそれらの使用
|
|
GB2560198B
(en)
|
2017-03-03 |
2020-10-07 |
Guala Closures Int B V |
Tamper evident closure
|
|
SG11202000669VA
(en)
*
|
2017-08-02 |
2020-02-27 |
Sunovion Pharmaceuticals Inc |
Isochroman compounds and uses thereof
|
|
KR20210139376A
(ko)
|
2019-03-14 |
2021-11-22 |
선오비온 파마슈티컬스 인코포레이티드 |
이소크로마닐 화합물의 염, 및 이의 결정성 형태, 제조방법, 치료 용도 및 약제학적 조성물
|
|
US20240190835A1
(en)
*
|
2021-04-08 |
2024-06-13 |
Sunovion Pharmaceuticals Inc. |
Isochroman derivatives and compositions and uses thereof
|