AU4589800A - 9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors - Google Patents

9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors

Info

Publication number
AU4589800A
AU4589800A AU45898/00A AU4589800A AU4589800A AU 4589800 A AU4589800 A AU 4589800A AU 45898/00 A AU45898/00 A AU 45898/00A AU 4589800 A AU4589800 A AU 4589800A AU 4589800 A AU4589800 A AU 4589800A
Authority
AU
Australia
Prior art keywords
dihydropurin
tetrahydronaphthalen
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45898/00A
Inventor
Richard John Davenport
Hazel Joan Dyke
Frances Celia Anne Galvin
Alan Findlay Haughan
Christopher Lowe
John Gary Montana
Catherine Louise Picken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9910371.5A external-priority patent/GB9910371D0/en
Priority claimed from GBGB9930199.6A external-priority patent/GB9930199D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of AU4589800A publication Critical patent/AU4589800A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU45898/00A 1999-05-05 2000-05-05 9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors Abandoned AU4589800A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9910371.5A GB9910371D0 (en) 1999-05-05 1999-05-05 Heterocyclic compounds and thier therapeutic agents
GB9910371 1999-05-05
GB9930199 1999-12-21
GBGB9930199.6A GB9930199D0 (en) 1999-12-21 1999-12-21 Heterocyclic compounds and their therapeutic use
PCT/GB2000/001709 WO2000068230A1 (en) 1999-05-05 2000-05-05 9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7 inhibitors

Publications (1)

Publication Number Publication Date
AU4589800A true AU4589800A (en) 2000-11-21

Family

ID=26315512

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45898/00A Abandoned AU4589800A (en) 1999-05-05 2000-05-05 9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors

Country Status (2)

Country Link
AU (1) AU4589800A (en)
WO (1) WO2000068230A1 (en)

Families Citing this family (35)

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DE19950647A1 (en) * 1999-10-21 2001-04-26 Merck Patent Gmbh Benzopyranoimidazolone and benzothiopyranoimidazolone derivatives as phosphodiesterase-VII inhibitors useful for treatment of e.g. asthma, psoriasis, osteoporosis, cachexia, sepsis, tumors and AIDS
EP2206703A1 (en) * 2008-12-30 2010-07-14 Bayer CropScience AG Pyrimidine derivatives and use thereof for combating undesired plant growth
US6903109B2 (en) 2001-04-18 2005-06-07 Ortho-Muniel Pharmaceutical, Inc. Arylindenopyridines and related therapeutic and prophylactic methods
US6958328B2 (en) 2001-04-18 2005-10-25 Ortho-Mcneil Pharmaceutical, Inc Arylindenopyridines and related therapeutic and prophylactic methods
WO2002088079A2 (en) * 2001-05-01 2002-11-07 Bristol-Myers Squibb Company Dual inhibitors of pde 7 and pde 4
PE20030008A1 (en) 2001-06-19 2003-01-22 Bristol Myers Squibb Co DUAL INHIBITORS OF PDE 7 AND PDE 4
EP2336133A1 (en) 2001-10-30 2011-06-22 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
BR0207215A (en) * 2001-12-13 2004-02-10 Daiichi Suntory Pharma Co Ltd Pyrazolopyriminone derivatives having pde7 inhibition action
WO2003064389A1 (en) * 2002-01-31 2003-08-07 Ono Pharmaceutical Co., Ltd. Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient
US20040127510A1 (en) 2002-04-16 2004-07-01 Heintzelman Geoffrey R. Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
EA010160B1 (en) 2003-09-18 2008-06-30 Конформа Терапьютикс Корпорейшн Novel heterocyclic compounds as hsp90-inhibitors
BRPI0609509A2 (en) 2005-03-30 2010-04-13 Conforma Therapeutics Corp pharmaceutically acceptable compound or a polymorph, solvate, tautomer, enantiomer, prodrug or salt thereof, pharmaceutical composition, and, use of the pharmaceutically acceptable compound, polymorph, solvate, tautomer, enantiomer, prodrug or salt
NZ568694A (en) 2005-11-09 2011-09-30 Zalicus Inc Method, compositions, and kits for the treatment of medical conditions
US8637528B2 (en) 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
CA2681650C (en) 2007-03-27 2016-11-22 Omeros Corporation The use of pde7 inhibitors for the treatment of movement disorders
RU2641648C1 (en) 2009-12-04 2018-01-19 Суновион Фармасьютикалз, Инк. Polycyclic compounds and methods for their use
KR102385359B1 (en) 2010-11-08 2022-04-11 오메로스 코포레이션 Treatment of addiction and impulse-control disorders using pde7 inhibitors
US9220715B2 (en) 2010-11-08 2015-12-29 Omeros Corporation Treatment of addiction and impulse-control disorders using PDE7 inhibitors
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
CN110087687A (en) 2016-07-29 2019-08-02 赛诺维信制药公司 Compound, composition and application thereof
UA125519C2 (en) 2016-07-29 2022-04-13 Суновіон Фармасьютікалз Інк. Compounds and compositions and uses thereof
IL268694B2 (en) 2017-02-16 2023-10-01 Sunovion Pharmaceuticals Inc Treatment of schizophrenia
US10357493B2 (en) 2017-03-10 2019-07-23 Selenity Therapeutics (Bermuda), Ltd. Metalloenzyme inhibitor compounds
JP7191085B2 (en) 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク Isochroman compounds and uses thereof
JP7453148B2 (en) 2018-02-16 2024-03-19 サノビオン ファーマシューティカルズ インク Salts, crystalline forms, and their production methods
US11136304B2 (en) 2019-03-14 2021-10-05 Sunovion Pharmaceuticals Inc. Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof
JP2023523569A (en) 2020-04-14 2023-06-06 サノビオン ファーマシューティカルズ インク Methods of treating neurological and psychiatric disorders
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
WO2022006456A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic pyridone compounds as jak2 v617f inhibitors
CR20230057A (en) 2020-07-02 2023-08-15 Incyte Corp Tricyclic urea compounds as jak2 v617f inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
US11958861B2 (en) 2021-02-25 2024-04-16 Incyte Corporation Spirocyclic lactams as JAK2 V617F inhibitors
WO2024038090A1 (en) 2022-08-18 2024-02-22 Mitodicure Gmbh Use of substituted benzoxazole and benzofuran compounds for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485917A (en) * 1966-04-14 1969-12-23 Janssen Pharmaceutica Nv Composition and method for combating fungus with imidazole carboxylates
GB1479544A (en) * 1974-02-07 1977-07-13 American Cyanamid Co 1,2,3,4-tetrahydro-1-naphthylurea derivatives their preparation and their use
US4201860A (en) * 1978-05-09 1980-05-06 Bristol-Myers Company Purine derivatives
US4172829A (en) * 1978-05-09 1979-10-30 Bristol-Myers Company 2,9-Disubstituted adenine derivatives and their use as non-adrenergic bronchodilators
EP0710239B1 (en) * 1993-07-23 1999-02-10 Merrell Pharmaceuticals Inc. Novel 9-n-bicyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines

Also Published As

Publication number Publication date
WO2000068230A1 (en) 2000-11-16

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase