DK3256466T3 - 1-heterocyclyl-isochromanylforbindelser og analoger til behandling af cns-forstyrrelser - Google Patents
1-heterocyclyl-isochromanylforbindelser og analoger til behandling af cns-forstyrrelser Download PDFInfo
- Publication number
- DK3256466T3 DK3256466T3 DK16708262.7T DK16708262T DK3256466T3 DK 3256466 T3 DK3256466 T3 DK 3256466T3 DK 16708262 T DK16708262 T DK 16708262T DK 3256466 T3 DK3256466 T3 DK 3256466T3
- Authority
- DK
- Denmark
- Prior art keywords
- isochromanyl
- heterocyclyl
- analogs
- compounds
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562115064P | 2015-02-11 | 2015-02-11 | |
| PCT/US2016/017539 WO2016130796A1 (en) | 2015-02-11 | 2016-02-11 | 1-heterocyclyl isochromanyl compounds and analogs for treating cns disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3256466T3 true DK3256466T3 (da) | 2022-05-02 |
Family
ID=55456908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16708262.7T DK3256466T3 (da) | 2015-02-11 | 2016-02-11 | 1-heterocyclyl-isochromanylforbindelser og analoger til behandling af cns-forstyrrelser |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US9856238B2 (da) |
| EP (2) | EP4046995B1 (da) |
| JP (3) | JP6657241B2 (da) |
| KR (1) | KR102601972B1 (da) |
| CN (2) | CN107531674B (da) |
| AU (1) | AU2016219253C1 (da) |
| CA (1) | CA2976095C (da) |
| DK (1) | DK3256466T3 (da) |
| EA (1) | EA201791804A1 (da) |
| ES (1) | ES2911910T3 (da) |
| HU (1) | HUE058698T2 (da) |
| IL (1) | IL253914B (da) |
| MX (2) | MX371404B (da) |
| MY (1) | MY188160A (da) |
| NZ (1) | NZ735011A (da) |
| PH (1) | PH12017501422A1 (da) |
| PL (1) | PL3256466T3 (da) |
| PT (1) | PT3256466T (da) |
| SG (2) | SG10201806809QA (da) |
| UA (1) | UA122222C2 (da) |
| WO (1) | WO2016130796A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX371404B (es) * | 2015-02-11 | 2020-01-29 | Sunovion Pharmaceuticals Inc | Compuestos y analogos de 1-heterociclil isocromanilo para el tratamiento de trastornos del sistema nervioso central (snc). |
| BR112017017349B1 (pt) * | 2015-02-11 | 2024-01-23 | Pgi Drug Discovery Llc | Composto e seu uso, composição, processo para preparar um composto e processo para separar um composto |
| EA201990399A1 (ru) | 2016-07-29 | 2019-07-31 | Суновион Фармасьютикалз, Инк. | Соединения, композиции и их применение |
| CN116283877A (zh) * | 2016-07-29 | 2023-06-23 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
| MX2019015150A (es) | 2017-06-30 | 2020-08-13 | Chase Therapeutics Corp | Composiciones antagonistas de nk-1 y métodos para su uso en el tratamiento de la depresión. |
| EA202090414A1 (ru) | 2017-08-02 | 2020-05-28 | Суновион Фармасьютикалз Инк. | Соединения и их применение |
| AU2020236225A1 (en) | 2019-03-14 | 2021-09-16 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3438995A (en) | 1968-01-08 | 1969-04-15 | Melville Sahyun | Diazaheterocyclic substituted benz-oxaheterocyclic compounds |
| US4963568A (en) | 1989-05-31 | 1990-10-16 | Abbott Laboratories | Dopamine agonists |
| US5621133A (en) | 1989-05-31 | 1997-04-15 | Deninno; Michael P. | Dopamine agonists |
| IE73232B1 (en) * | 1990-05-25 | 1997-05-21 | Akzo Nv | Isochromane derivatives |
| US5238939A (en) * | 1990-05-25 | 1993-08-24 | Akzo N.V. | Isochromane derivatives |
| EP1089993B1 (en) | 1998-06-30 | 2003-10-22 | Eli Lilly And Company | 5-ht1f agonists |
| SE9902267D0 (sv) | 1999-06-16 | 1999-06-16 | Astra Ab | New compounds |
| KR20050043776A (ko) * | 2001-11-08 | 2005-05-11 | 세프라코 아이엔시. | 거울상 이성질체로 농축된, 시탈로프람의 데스메틸 및디데스메틸 대사물을 이용한 우울증 및 다른 중추신경계질환 치료방법 |
| RU2396266C2 (ru) * | 2004-12-21 | 2010-08-10 | Ф. Хоффманн-Ля Рош Аг | Производные хромана и их применения при лечении заболеваний цнс |
| EP1874756A1 (en) | 2005-04-22 | 2008-01-09 | Wyeth | Chromane and chromene derivatives and uses thereof |
| RU2440344C2 (ru) * | 2006-01-27 | 2012-01-20 | Ф.Хоффманн-Ля Рош Аг | Применение 2-имидазолов для лечения расстройств цнс |
| KR101103118B1 (ko) | 2007-11-02 | 2012-01-04 | 동아제약주식회사 | 신규한 1,3-디히드로-5-이소벤조퓨란카르보니트릴 유도체 화합물 및 이를 함유하는 조루증 치료용 약학조성물 |
| CN102762575B (zh) | 2009-12-04 | 2015-04-15 | 桑诺维恩药品公司 | 多环化合物及其使用方法 |
| WO2012122340A1 (en) | 2011-03-10 | 2012-09-13 | Boehringer Ingelheim International Gmbh | Soluble guanylate cyclase activators |
| AR090557A1 (es) | 2012-04-02 | 2014-11-19 | Orion Corp | DERIVADOS IMIDAZOLICOS AGONISTAS ADRENERGICOS a2 |
| CA2896871A1 (en) * | 2012-12-31 | 2014-07-03 | Kerry L. Spear | Heterocyclic compounds and methods of use thereof |
| MX371404B (es) * | 2015-02-11 | 2020-01-29 | Sunovion Pharmaceuticals Inc | Compuestos y analogos de 1-heterociclil isocromanilo para el tratamiento de trastornos del sistema nervioso central (snc). |
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2016
- 2016-02-11 MX MX2017010363A patent/MX371404B/es active IP Right Grant
- 2016-02-11 JP JP2017542401A patent/JP6657241B2/ja active Active
- 2016-02-11 WO PCT/US2016/017539 patent/WO2016130796A1/en active Application Filing
- 2016-02-11 EA EA201791804A patent/EA201791804A1/ru unknown
- 2016-02-11 DK DK16708262.7T patent/DK3256466T3/da active
- 2016-02-11 PT PT167082627T patent/PT3256466T/pt unknown
- 2016-02-11 EP EP22166538.3A patent/EP4046995B1/en active Active
- 2016-02-11 UA UAA201708945A patent/UA122222C2/uk unknown
- 2016-02-11 PL PL16708262T patent/PL3256466T3/pl unknown
- 2016-02-11 AU AU2016219253A patent/AU2016219253C1/en active Active
- 2016-02-11 ES ES16708262T patent/ES2911910T3/es active Active
- 2016-02-11 HU HUE16708262A patent/HUE058698T2/hu unknown
- 2016-02-11 SG SG10201806809QA patent/SG10201806809QA/en unknown
- 2016-02-11 MY MYPI2017702923A patent/MY188160A/en unknown
- 2016-02-11 SG SG11201706515QA patent/SG11201706515QA/en unknown
- 2016-02-11 CA CA2976095A patent/CA2976095C/en active Active
- 2016-02-11 NZ NZ735011A patent/NZ735011A/en unknown
- 2016-02-11 CN CN201680018639.XA patent/CN107531674B/zh active Active
- 2016-02-11 EP EP16708262.7A patent/EP3256466B9/en active Active
- 2016-02-11 KR KR1020177025290A patent/KR102601972B1/ko active IP Right Grant
- 2016-02-11 US US15/041,852 patent/US9856238B2/en active Active
- 2016-02-11 MX MX2020001157A patent/MX2020001157A/es unknown
- 2016-02-11 CN CN202010607608.6A patent/CN111925360B/zh active Active
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2017
- 2017-08-08 IL IL253914A patent/IL253914B/en unknown
- 2017-08-09 PH PH12017501422A patent/PH12017501422A1/en unknown
- 2017-11-21 US US15/819,372 patent/US10336732B2/en active Active
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2019
- 2019-05-06 US US16/403,698 patent/US11192885B2/en active Active
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2020
- 2020-02-05 JP JP2020018081A patent/JP7023994B2/ja active Active
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2021
- 2021-10-29 US US17/452,786 patent/US20220185799A1/en active Pending
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2022
- 2022-02-09 JP JP2022018580A patent/JP2022065050A/ja active Pending
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