JP2019513776A5 - - Google Patents
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- JP2019513776A5 JP2019513776A5 JP2018553486A JP2018553486A JP2019513776A5 JP 2019513776 A5 JP2019513776 A5 JP 2019513776A5 JP 2018553486 A JP2018553486 A JP 2018553486A JP 2018553486 A JP2018553486 A JP 2018553486A JP 2019513776 A5 JP2019513776 A5 JP 2019513776A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- hydrogen
- formula
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- TXIOGJHPPVXTOY-UHFFFAOYSA-N CCN1CCN(C)CC1 Chemical compound CCN1CCN(C)CC1 TXIOGJHPPVXTOY-UHFFFAOYSA-N 0.000 description 1
- HVCNXQOWACZAFN-UHFFFAOYSA-N CCN1CCOCC1 Chemical compound CCN1CCOCC1 HVCNXQOWACZAFN-UHFFFAOYSA-N 0.000 description 1
- YASSUAIJFUESOY-UHFFFAOYSA-N CN(C1)CC1(F)F Chemical compound CN(C1)CC1(F)F YASSUAIJFUESOY-UHFFFAOYSA-N 0.000 description 1
- DERXELLTUOVDQH-UHFFFAOYSA-N CN(C1)CC1F Chemical compound CN(C1)CC1F DERXELLTUOVDQH-UHFFFAOYSA-N 0.000 description 1
- SJRJJKPEHAURKC-UHFFFAOYSA-N CN1CCOCC1 Chemical compound CN1CCOCC1 SJRJJKPEHAURKC-UHFFFAOYSA-N 0.000 description 1
- WBYNAIWXICBRLD-UHFFFAOYSA-N Cc(c(N)c(c(N)c1N)N)c1N Chemical compound Cc(c(N)c(c(N)c1N)N)c1N WBYNAIWXICBRLD-UHFFFAOYSA-N 0.000 description 1
- 0 Cc1c(C)c(*)c(*)nc1C Chemical compound Cc1c(C)c(*)c(*)nc1C 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16165572 | 2016-04-15 | ||
| EP16165572.5 | 2016-04-15 | ||
| PCT/EP2017/058519 WO2017178416A1 (en) | 2016-04-15 | 2017-04-10 | Pyrazolopyrimidine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019513776A JP2019513776A (ja) | 2019-05-30 |
| JP2019513776A5 true JP2019513776A5 (enExample) | 2020-05-21 |
| JP7051703B2 JP7051703B2 (ja) | 2022-04-11 |
Family
ID=55755480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018553486A Active JP7051703B2 (ja) | 2016-04-15 | 2017-04-10 | ピラゾロピリミジン誘導体 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10604525B2 (enExample) |
| EP (1) | EP3442974B8 (enExample) |
| JP (1) | JP7051703B2 (enExample) |
| KR (1) | KR102467347B1 (enExample) |
| CN (1) | CN109071545B (enExample) |
| AR (1) | AR108130A1 (enExample) |
| AU (1) | AU2017251155B2 (enExample) |
| CA (1) | CA3020793C (enExample) |
| CL (1) | CL2018002920A1 (enExample) |
| CO (1) | CO2018010966A2 (enExample) |
| DO (1) | DOP2018000226A (enExample) |
| ES (1) | ES2953467T3 (enExample) |
| IL (1) | IL261885A (enExample) |
| MX (1) | MX389697B (enExample) |
| PH (1) | PH12018550173A1 (enExample) |
| PL (1) | PL3442974T3 (enExample) |
| RU (1) | RU2769448C2 (enExample) |
| SG (1) | SG11201808214TA (enExample) |
| TW (1) | TWI742067B (enExample) |
| UY (1) | UY37201A (enExample) |
| WO (1) | WO2017178416A1 (enExample) |
| ZA (1) | ZA201807656B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016022066A1 (en) | 2014-08-04 | 2016-02-11 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| RS60302B1 (sr) | 2016-04-15 | 2020-07-31 | Abbvie Inc | Inhibitori bromodomena |
| PL3442974T3 (pl) * | 2016-04-15 | 2023-12-04 | Elanco Animal Health Gmbh | Pochodne pirazolopirymidyny |
| CN118021814A (zh) | 2017-04-21 | 2024-05-14 | Epizyme股份有限公司 | 用ehmt2抑制剂进行的组合疗法 |
| CA3061406A1 (en) * | 2017-04-27 | 2018-11-01 | Bayer Animal Health Gmbh | New bicyclic pyrazole derivatives |
| MX2020002869A (es) | 2017-09-15 | 2020-07-24 | Aduro Biotech Inc | Compuestos de pirazolopirimidinona y usos de los mismos. |
| KR20250057155A (ko) | 2017-12-15 | 2025-04-28 | 타르서스 파마수티칼스, 아이엔씨. | 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법 |
| CA3099610A1 (en) | 2018-05-09 | 2019-11-14 | Bayer Animal Health Gmbh | New quinoline derivatives |
| MX2021000293A (es) | 2018-07-09 | 2021-07-15 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos antihelminticos. |
| EP3643711A1 (en) | 2018-10-24 | 2020-04-29 | Bayer Animal Health GmbH | New anthelmintic compounds |
| PL3897842T3 (pl) * | 2018-12-18 | 2025-05-19 | Elanco Tiergesundheit Ag | Pochodne bicykliczne |
| US20220064160A1 (en) * | 2018-12-18 | 2022-03-03 | Elanco Tiergesundheit Ag | Bicyclic derivatives |
| BR112021018631A2 (pt) * | 2019-03-19 | 2021-11-23 | Boehringer Ingelheim Animal Health Usa Inc | Compostos anti-helmínticos de aza-benzotiofeno e aza-benzofurano |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| CN114206860B (zh) * | 2019-06-07 | 2025-02-18 | 礼蓝动物保健有限公司 | 用于治疗体内寄生虫的双环衍生物 |
| TWI865563B (zh) | 2019-07-30 | 2024-12-11 | 德商拜耳動物保健有限公司 | 新穎異喹啉衍生物 |
| WO2021122911A1 (en) | 2019-12-18 | 2021-06-24 | Intervet International B.V. | Anthelmintic compounds comprising a quinoline structure |
| MX2022007671A (es) * | 2019-12-18 | 2022-07-19 | Intervet Int Bv | Compuestos antihelminticos que comprenden una estructura de azaindoles. |
| WO2021242581A1 (en) * | 2020-05-29 | 2021-12-02 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic heterocyclic compounds |
| CN116685584A (zh) * | 2020-11-18 | 2023-09-01 | 礼蓝动物保健有限公司 | 用于治疗心丝虫感染的n-(2,3-二氢-1,4-苯并噁嗪-4-基)-3-异丙基-7-(2,3,5-三氟苯基)苯并噻吩-2-甲酰胺衍生物和类似化合物 |
| WO2022106469A2 (en) | 2020-11-18 | 2022-05-27 | Elanco Tiergesundheit Ag | N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections |
| TW202237600A (zh) | 2020-12-04 | 2022-10-01 | 瑞士商禮藍動物保健股份有限公司 | 雙環衍生物 |
| AU2021395477A1 (en) * | 2020-12-11 | 2023-06-22 | Intervet International B.V. | Anthelmintic compounds comprising a thienopyridine structure |
| CN113252824B (zh) * | 2021-06-17 | 2022-04-19 | 湖南农业大学 | 测定水体中三氟苯嘧啶含量的气相色谱-电子捕获检测器法 |
| KR102660894B1 (ko) * | 2021-09-17 | 2024-04-26 | 기초과학연구원 | 피리미딘-2-아민 화합물의 제조방법 |
| UY39995A (es) | 2021-11-01 | 2023-05-15 | Boehringer Ingelheim Vetmedica GmbH | Compuestos de pirrolopiridazina como antihelmínticos |
| WO2024213752A1 (en) | 2023-04-14 | 2024-10-17 | Elanco Animal Health Gmbh | Long-term prevention and/or treatment of a disease by slo-1 inhibitors |
| CN121620507A (zh) | 2023-08-02 | 2026-03-06 | 英特维特国际股份有限公司 | 具有驱虫活性的甲酰胺-4-喹啉化合物 |
| CN119139315B (zh) * | 2024-09-23 | 2026-03-10 | 大连大学 | D724-0491在制备治疗乳腺癌药物中的应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY125533A (en) | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
| RU15525U1 (ru) | 2000-07-04 | 2000-10-20 | Федеральный научно-производственный центр закрытое акционерное общество "Научно-производственный концерн (объединение) "ЭНЕРГИЯ" | Электродвигатель постоянного тока |
| US7662826B2 (en) * | 2002-04-23 | 2010-02-16 | Shionogi & Co., Ltd. | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same |
| GB0213715D0 (en) | 2002-06-14 | 2002-07-24 | Syngenta Ltd | Chemical compounds |
| TWI312272B (en) | 2003-05-12 | 2009-07-21 | Sumitomo Chemical Co | Pyrimidine compound and pests controlling composition containing the same |
| EA009517B1 (ru) * | 2003-06-27 | 2008-02-28 | Байер Кропсайенс Аг | Пиразолопиримидины |
| CA2530378A1 (en) | 2003-06-27 | 2005-01-06 | Bayer Cropscience Ag | Pyrazolopyrimidines |
| GB0414438D0 (en) | 2004-06-28 | 2004-07-28 | Syngenta Participations Ag | Chemical compounds |
| RU2394819C2 (ru) | 2004-10-20 | 2010-07-20 | Кумиай Кемикал Индастри Ко., Лтд. | Инсектицид, акарицид и нематоцид, содержащие в качестве активного компонента производное 3-триазолилфенилсульфида |
| BRPI0616667B1 (pt) | 2005-10-06 | 2017-07-18 | Nippon Soda Co. , Ltd. | Compounds of cyclical amine or salts thereof or non-oxides thereof, and agents for control of fever |
| EP1918291A1 (en) * | 2006-10-30 | 2008-05-07 | Novartis AG | 3-Aminocarbonyl-substituted fused pyrazolo-derivatives as protein kinase modulators |
| CA2670083A1 (en) * | 2006-11-20 | 2008-05-29 | Alantos Pharmaceuticals Holding, Inc. | Heterobicyclic metalloprotease inhibitors |
| US8729264B2 (en) | 2007-09-28 | 2014-05-20 | Kyowa Hakko Kirin Co., Ltd. | Agent for prevention and/or treatment of skin diseases |
| JP5268461B2 (ja) | 2008-07-14 | 2013-08-21 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | Ｐｆ１３６４物質、その製造方法、生産菌株、及び、それを有効成分とする農園芸用殺虫剤 |
| CN101337937B (zh) | 2008-08-12 | 2010-12-22 | 国家农药创制工程技术研究中心 | 具有杀虫活性的n-苯基-5-取代氨基吡唑类化合物 |
| CN101337940B (zh) | 2008-08-12 | 2012-05-02 | 国家农药创制工程技术研究中心 | 具杀虫活性的含氮杂环二氯烯丙醚类化合物 |
| CN101715774A (zh) | 2008-10-09 | 2010-06-02 | 浙江化工科技集团有限公司 | 一个具有杀虫活性化合物制备及用途 |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| GB0820344D0 (en) | 2008-11-06 | 2008-12-17 | Syngenta Ltd | Herbicidal compositions |
| US8007468B2 (en) | 2009-07-13 | 2011-08-30 | Navilyst Medical, Inc. | Method to secure an elastic component in a valve |
| WO2011085575A1 (zh) | 2010-01-15 | 2011-07-21 | 江苏省农药研究所股份有限公司 | 邻杂环甲酰苯胺类化合物及其合成方法和应用 |
| PE20131380A1 (es) | 2010-08-31 | 2014-01-05 | Meiji Seika Pharma Co Ltd | Agente de control de plagas |
| CN101967139B (zh) | 2010-09-14 | 2013-06-05 | 中化蓝天集团有限公司 | 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用 |
| WO2012112363A1 (en) | 2011-02-14 | 2012-08-23 | Merck Sharp & Dohme Corp. | Cathepsin cysteine protease inhibitors |
| WO2013050317A1 (en) | 2011-10-03 | 2013-04-11 | Syngenta Limited | Polymorphs of an isoxazoline derivative |
| CN102391261A (zh) | 2011-10-14 | 2012-03-28 | 上海交通大学 | 一种n-取代噁二嗪类化合物及其制备方法和应用 |
| US9334238B2 (en) | 2012-03-30 | 2016-05-10 | Basf Se | N-substituted pyridinylidenes for combating animal pests |
| EP2647626A1 (en) | 2012-04-03 | 2013-10-09 | Syngenta Participations AG. | 1-Aza-spiro[4.5]dec-3-ene and 1,8-diaza-spiro[4.5]dec-3-ene derivatives as pesticides |
| NZ700595A (en) | 2012-04-27 | 2016-04-29 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| WO2014070978A1 (en) | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| CN103232431B (zh) | 2013-01-25 | 2014-11-05 | 青岛科技大学 | 一种二卤代吡唑酰胺类化合物及其应用 |
| CN103109816B (zh) | 2013-01-25 | 2014-09-10 | 青岛科技大学 | 硫代苯甲酰胺类化合物及其应用 |
| US20140275503A1 (en) | 2013-03-13 | 2014-09-18 | Dow Agrosciences Llc | Process for the preparation of certain triaryl rhamnose carbamates |
| CN103265527B (zh) | 2013-06-07 | 2014-08-13 | 江苏省农用激素工程技术研究中心有限公司 | 邻氨基苯甲酰胺化合物及其制备方法和应用 |
| CN103524422B (zh) | 2013-10-11 | 2015-05-27 | 中国农业科学院植物保护研究所 | 苯并咪唑衍生物及其制备方法和用途 |
| CA2925873A1 (en) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| MX2016004942A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
| UY36196A (es) * | 2014-07-25 | 2016-02-29 | Bayer Animal Health Gmbh | Compuestos para usar en el tratamiento antihelmíntico |
| PL3442974T3 (pl) | 2016-04-15 | 2023-12-04 | Elanco Animal Health Gmbh | Pochodne pirazolopirymidyny |
-
2017
- 2017-04-10 PL PL17715204.8T patent/PL3442974T3/pl unknown
- 2017-04-10 US US16/093,565 patent/US10604525B2/en active Active
- 2017-04-10 ES ES17715204T patent/ES2953467T3/es active Active
- 2017-04-10 CN CN201780023855.8A patent/CN109071545B/zh active Active
- 2017-04-10 CA CA3020793A patent/CA3020793C/en active Active
- 2017-04-10 WO PCT/EP2017/058519 patent/WO2017178416A1/en not_active Ceased
- 2017-04-10 SG SG11201808214TA patent/SG11201808214TA/en unknown
- 2017-04-10 AU AU2017251155A patent/AU2017251155B2/en active Active
- 2017-04-10 MX MX2018012544A patent/MX389697B/es unknown
- 2017-04-10 KR KR1020187032684A patent/KR102467347B1/ko active Active
- 2017-04-10 EP EP17715204.8A patent/EP3442974B8/en active Active
- 2017-04-10 JP JP2018553486A patent/JP7051703B2/ja active Active
- 2017-04-10 RU RU2018140092A patent/RU2769448C2/ru active
- 2017-04-12 AR ARP170100939A patent/AR108130A1/es active IP Right Grant
- 2017-04-13 TW TW106112313A patent/TWI742067B/zh active
- 2017-04-18 UY UY0001037201A patent/UY37201A/es not_active Application Discontinuation
-
2018
- 2018-09-20 IL IL261885A patent/IL261885A/en unknown
- 2018-10-12 CL CL2018002920A patent/CL2018002920A1/es unknown
- 2018-10-12 DO DO2018000226A patent/DOP2018000226A/es unknown
- 2018-10-12 CO CONC2018/0010966A patent/CO2018010966A2/es unknown
- 2018-10-15 PH PH12018550173A patent/PH12018550173A1/en unknown
- 2018-11-14 ZA ZA2018/07656A patent/ZA201807656B/en unknown
-
2020
- 2020-01-29 US US16/776,374 patent/US11001590B2/en active Active
- 2020-01-29 US US16/776,377 patent/US10934301B2/en active Active
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