UY37201A - Nuevos derivados de pirazolopirimidina - Google Patents

Nuevos derivados de pirazolopirimidina

Info

Publication number
UY37201A
UY37201A UY0001037201A UY37201A UY37201A UY 37201 A UY37201 A UY 37201A UY 0001037201 A UY0001037201 A UY 0001037201A UY 37201 A UY37201 A UY 37201A UY 37201 A UY37201 A UY 37201A
Authority
UY
Uruguay
Prior art keywords
compounds
pirazolopirimidina
new derivatives
preparing
pharmaceutical compositions
Prior art date
Application number
UY0001037201A
Other languages
English (en)
Inventor
Johannes Köbberling Dr
Adeline Köhler Dra
Claudia Welz Dra
Kirsten Börngen Dra
Daniel Kulke Dr
Dr Thomas Ilg Prof
Walter Hübsch Dr
Hans-Georg Schwarz Dr
Görgens Ulrich
Ulrich Ebbinghaus-Kintscher Dr
Maike Hink Dra
Dirk Nennstiel Dr
Klaus Raming Dr
Martin Adamczewski Dr
Böhm Claudia
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of UY37201A publication Critical patent/UY37201A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invención abarca compuestos pirazolopirimidina de fórmula general (I): en donde n, o, X, Y, R, Q, R1, R2, R3 y R4 son como se definen en la presente, métodos para preparar dichos compuestos, compuestos intermediarios útiles para preparar dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la fabricación de composiciones farmacéuticas para el tratamiento, control y/o prevención de enfermedades, en particular de infecciones helmínticas, como agente único o en combinación con otros ingredientes activos.
UY0001037201A 2016-04-15 2017-04-18 Nuevos derivados de pirazolopirimidina UY37201A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16165572 2016-04-15

Publications (1)

Publication Number Publication Date
UY37201A true UY37201A (es) 2017-11-30

Family

ID=55755480

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001037201A UY37201A (es) 2016-04-15 2017-04-18 Nuevos derivados de pirazolopirimidina

Country Status (22)

Country Link
US (3) US10604525B2 (es)
EP (1) EP3442974B8 (es)
JP (1) JP7051703B2 (es)
KR (1) KR102467347B1 (es)
CN (1) CN109071545B (es)
AR (1) AR108130A1 (es)
AU (1) AU2017251155B2 (es)
CA (1) CA3020793C (es)
CL (1) CL2018002920A1 (es)
CO (1) CO2018010966A2 (es)
DO (1) DOP2018000226A (es)
ES (1) ES2953467T3 (es)
IL (1) IL261885A (es)
MX (1) MX2018012544A (es)
PH (1) PH12018550173A1 (es)
PL (1) PL3442974T3 (es)
RU (1) RU2769448C2 (es)
SG (1) SG11201808214TA (es)
TW (1) TWI742067B (es)
UY (1) UY37201A (es)
WO (1) WO2017178416A1 (es)
ZA (1) ZA201807656B (es)

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JP2020533376A (ja) 2017-09-15 2020-11-19 アドゥロ バイオテック，インク． ピラゾロピリミジノン化合物およびその使用
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AR116909A1 (es) * 2018-12-18 2021-06-23 Elanco Tiergesundheit Ag Derivados bicíclicos
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US20200385398A1 (en) * 2019-06-07 2020-12-10 Elanco Tiergesundheit Ag New bicyclic derivatives
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TW202237600A (zh) 2020-12-04 2022-10-01 瑞士商禮藍動物保健股份有限公司 雙環衍生物
CA3203279A1 (en) 2020-12-11 2022-06-16 Intervet International B.V. Anthelmintic compounds comprising a thienopyridine structure
CN113252824B (zh) * 2021-06-17 2022-04-19 湖南农业大学 测定水体中三氟苯嘧啶含量的气相色谱-电子捕获检测器法
KR102660894B1 (ko) * 2021-09-17 2024-04-26 기초과학연구원 피리미딘-2-아민 화합물의 제조방법
CA3236894A1 (en) 2021-11-01 2023-05-04 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds

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Also Published As

Publication number Publication date
AU2017251155A1 (en) 2018-10-11
RU2769448C2 (ru) 2022-03-31
RU2018140092A (ru) 2020-05-15
SG11201808214TA (en) 2018-10-30
CA3020793A1 (en) 2017-10-19
WO2017178416A1 (en) 2017-10-19
ES2953467T3 (es) 2023-11-13
TWI742067B (zh) 2021-10-11
US20190071447A1 (en) 2019-03-07
US10604525B2 (en) 2020-03-31
RU2018140092A3 (es) 2020-06-25
AR108130A1 (es) 2018-07-18
MX2018012544A (es) 2019-01-31
CO2018010966A2 (es) 2018-10-22
IL261885A (en) 2018-10-31
US20200299299A1 (en) 2020-09-24
KR20180134966A (ko) 2018-12-19
PH12018550173A1 (en) 2019-07-15
CN109071545B (zh) 2021-08-03
US11001590B2 (en) 2021-05-11
US20200239482A1 (en) 2020-07-30
CN109071545A (zh) 2018-12-21
EP3442974B1 (en) 2023-06-07
EP3442974A1 (en) 2019-02-20
JP2019513776A (ja) 2019-05-30
DOP2018000226A (es) 2018-11-15
US10934301B2 (en) 2021-03-02
CA3020793C (en) 2024-05-21
KR102467347B1 (ko) 2022-11-14
PL3442974T3 (pl) 2023-12-04
JP7051703B2 (ja) 2022-04-11
TW201803874A (zh) 2018-02-01
CL2018002920A1 (es) 2019-02-01
AU2017251155B2 (en) 2021-08-05
ZA201807656B (en) 2024-06-26
EP3442974B8 (en) 2023-07-12
EP3442974C0 (en) 2023-06-07

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